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Francuzik, W.; Kraft, M.; Hofmeier, K. Scherer; Rueff, F.; Pfohler, C.; Treudler, R.; Lang, R.; Hawranek, T.; Wagner, N. und Worm, M. (2021): Anaphylaxie im mittleren Lebensalter. In: Allergologie, Bd. 44, Nr. 4: S. 297-305

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Abstract

Age is one of the most important factors influencing the course of anaphylaxis: moreover, the frequency of elicitors of anaphylaxis is age-associated. We analyzed 8,465 anaphylactic episodes in adult patients in three age groups with a focus on patients in the middle-age group (35 - 65 years old). Insect venom was the most frequent trigger in this age group (51.2%) followed by drugs (22.8%) and food (17.3%). Severe reactions were observed in 40.1% of middle-aged patients and occurred more frequently in this age group than in patients below 35 years (27.6%) and less frequently than in patients over 65 years (55.6%). The symptoms and comorbidity profile also changed with age, most significantly regarding the increase in rates of concomitant cardiologic diseases and (severe) cardiovascular symptoms.

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