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Gehlen, Heidrun; Inerle, Katharina; Utrich, Sebastian; Lehmann, Beatrice und Straubinger, Reinhard K. (2021): Anaplasmose beim Pferd – Ein Literaturreview unter Berücksichtigung aktueller Diagnose- und Therapieverfahren sowie möglicher Präventionsmaßnahmen. In: Pferdeheilkunde, Bd. 37, Nr. 1: S. 25-33

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Abstract

Equine diseases transmitted by ticks in Germany include Lyme borreliosis (infectious agent Borrelia burgdorferi sensu lato complex), granulocytic anaplasmosis (EGA, caused by Anaplasma phagocytophilum, Ap), tick-borne encephalitis (TBE-virus), and piroplasmosis (Babesia caballi, Theileria equi). EGA is not contagious so that only single animals are affected within a herd. Disease severity depends on the age of the horse and the duration of the disease. Apathy and fever are common clinical signs. Young horses (< 4 years) are mostly affected less severe. Most horses show a subclinical (in particular in endemic areas) or mild course of the disease. Small feral mammals serve as a reservoir. The diagnosis of EGA is based on the epizootic history (typical season and region, exposition to ticks), clinical and laboratory findings (PCR, granular inclusion bodies detected by cytology, culture). Also, serologic measures, including ELISA and immunofluorescence essay, are used. Fourfold increasing antibody levels assure the diagnosis. Antibodies can be detected 14 days post infection for up to two years. Effective antibiotic therapy for EGA is available, reducing the duration and severity of clinical signs. As Ap is an intracellular pathogen, tetracyclines are the antibiotics of choice (oxytetracycline IV 7 mg/kg BW SID for 5-7 days). No vaccine is available, therefore, prophylaxis includes tick control only.

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