Abstract
BACKGROUND: Intrasaccular flow-disruption represents a new paradigmin endovascular treatment of wide-necked bifurcation aneurysms. OBJECTIVE: To retrospectively compare Woven Endobridge ( WEB) embolization with microsurgical clipping for unruptured anterior circulation aneurysms using propensity score adjustment. METHODS: A total of 63 patients treated with WEB and 103 patients treated with clipping were compared based on the intention-to-treat principle. The primary outcome measures were immediate technical treatment success, major adverse events, and 6-mo complete aneurysm occlusion. RESULTS: The technical success rates were 83% for WEB and 100% for clipping. Procedu-rerelated complications occurred more often in the clipping group (13%) than the WEB group (6%, adjusted P < .01). However, the rates of major adverse events were comparable in both groups (WEB: 3%, clip: 4%, adjusted P = .53). At the 6-mo follow-up, favorable functional outcomes were achieved in 98% of the WEB embolization group and 99% of the clipping group (adjusted P = .19). Six-month complete aneurysmocclusion was obtained in 75% of the WEB group and 94% of the clipping group (adjusted P < .01). CONCLUSION: Microsurgical clipping was associated with higher technical success and complete occlusion rates, whereas WEB had a lower complication rate. Favorable functional outcomes were achieved in >= 98% of both groups. The decision to use a specific treatment modality should be made on an individual basis and in accordance with the patient's preferences.
| Dokumententyp: | Zeitschriftenartikel |
|---|---|
| Fakultät: | Medizin |
| Themengebiete: | 600 Technik, Medizin, angewandte Wissenschaften > 610 Medizin und Gesundheit |
| ISSN: | 0148-396X |
| Sprache: | Englisch |
| Dokumenten ID: | 98468 |
| Datum der Veröffentlichung auf Open Access LMU: | 05. Jun. 2023, 15:29 |
| Letzte Änderungen: | 17. Okt. 2023, 14:58 |
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