Nucleophilic Reactivities of Thiophenolates

Justel, Patrick M.; Pignot, Cedric D. and Ofial, Armin R. (2021): Nucleophilic Reactivities of Thiophenolates. In: Journal of Organic Chemistry, Vol. 86, No. 8: pp. 5965-5972

Abstract

The nucleophilic reactivities of substituted thiophenolates were determined by following the kinetics of their reactions with a series of quinone methides (reference electrophiles) in DMSO at 20 degrees C. The experimentally determined second-order rate constants were analyzed according to the Mayr-Patz equation log k = s(N)(N + E) to derive the nucleophile-specific reactivity parameters N and sN for ten thiophenolate ions.

• Item Type: Journal article
• Faculties: Chemistry and Pharmacy > Department of Chemistry
• Subjects: 500 Science > 540 Chemistry
• ISSN: 0022-3263
• Language: English