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Number of items: 9.
2025
Ouologuem, Lina; Kübler, Anna; Ouologuem, Sarah; Hadzic, Amar; Stöckl, Jan B.; Siciliano, Anna Chiara; Forciniti, Stefania; Nigro, Salvatore; Iuele, Helena; Onesto, Valentina; Nguyen, Anny; Matzek, Dana; Abrahamian, Carla; Grimm, Christian; Popper, Bastian; Gigli, Giuseppe; del Mercato, Loretta L.; Merkel, Olivia M.; Fröhlich, Thomas; Theurich, Sebastian und Bartel, Karin
(2025):
Loss of two-pore channel 2 enhances CD8+ T cell cytotoxicity and directly impairs tumour growth via MAPK axis in HCC.
In: Frontiers in Immunology, Vol. 16, 1668066
[PDF, 16MB]
2024
Abrahamian, Carla; Tang, Rachel; Deutsch, Rebecca; Ouologuem, Lina; Weiden, Eva-Maria; Kudrina, Veronika; Blenninger, Julia; Rilling, Julia; Feldmann, Colin; Kuss, Solveig; Stepanov, Youli; Rosato, Anna Scotto; Calvo, Guadalupe T.; Soengas, Maria S.; Mayr, Doris; Fröhlich, Thomas; Gudermann, Thomas; Biel, Martin; Wahl-Schott, Christian; Chen, Cheng-Chang; Bartel, Karin und Grimm, Christian
(2024):
Rab7a is an enhancer of TPC2 activity regulating melanoma progression through modulation of the GSK3β/β-Catenin/MITF-axis.
In: Nature Communications, Vol. 15, 10008
[PDF, 2MB]
2022
Scotto Rosato, Anna; Krogsaeter, Einar K; Jaślan, Dawid; Abrahamian, Carla; Montefusco, Sandro; Soldati, Chiara; Spix, Barbara; Pizzo, Maria Teresa; Grieco, Giuseppina; Böck, Julia; Wyatt, Amanda; Wünkhaus, Daniela; Passon, Marcel; Stieglitz, Marc; Keller, Marco; Hermey, Guido; Markmann, Sandra; Gruber‐Schoffnegger, Doris; Cotman, Susan; Johannes, Ludger; Crusius, Dennis; Boehm, Ulrich; Wahl-Schott, Christian; Biel, Martin; Bracher, Franz; De Leonibus, Elvira; Polishchuk, Elena; Medina, Diego L; Paquet, Dominik und Grimm, Christian
(5. August 2022):
TPC2 rescues lysosomal storage in mucolipidosis type IV , Niemann–Pick type C1, and Batten disease.
In: EMBO Molecular Medicine, Vol. 14, No. 9
[PDF, 27MB]
Yuan, Yu; Jaslan, Dawid; Rahman, Taufiq; Bolsover, Stephen R.; Arige, Vikas; Wagner, Larry E.; Abrahamian, Carla; Tang, Rachel; Keller, Marco; Hartmann, Jonas; Rosato, Anna S.; Weiden, Eva-Maria; Bracher, Franz; Yule, David I.; Grimm, Christian und Patel, Sandip
(2022):
Segregated cation flux by TPC2 biases Ca2+ signaling through lysosomes.
In: Nature Communications, Vol. 13, No. 1, 4481
2021
Rühl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Günter; Schaefer, Michael; Bracher, Franz 
ORCID: https://orcid.org/0000-0003-0009-8629 und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific reports, Vol. 11, No. 1, 8313
[PDF, 7MB]
ORCID: https://orcid.org/0000-0003-0009-8629 und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific reports, Vol. 11, No. 1, 8313
[PDF, 7MB]
Netcharoensirisuk, Ponsawan; Abrahamian, Carla; Tang, Rachel; Chen, Cheng-Chang; Rosato, Anna Scotto; Beyers, Wyatt; Chao, Yu-Kai; Filippini, Antonio; Di Pietro, Santiago; Bartel, Karin; Biel, Martin; Vollmar, Angelika M.; Umehara, Kaoru; De-Eknamkul, Wanchai und Grimm, Christian
(2021):
Flavonoids increase melanin production and reduce proliferation, migration and invasion of melanoma cells by blocking endolysosomal/melanosomal TPC2.
In: Scientific reports, Vol. 11, No. 1, 8515
[PDF, 4MB]
Abrahamian, Carla und Grimm, Christian
(2021):
Endolysosomal Cation Channels and MITF in Melanocytes and Melanoma.
In: Biomolecules, Vol. 11, No. 7, 1021
Ruehl, Philipp; Rosato, Anna Scotto; Urban, Nicole; Gerndt, Susanne; Tang, Rachel; Abrahamian, Carla; Leser, Charlotte; Sheng, Jiansong; Jha, Archana; Vollmer, Guenter; Schaefer, Michael; Bracher, Franz und Grimm, Christian
(2021):
Estradiol analogs attenuate autophagy, cell migration and invasion by direct and selective inhibition of TRPML1, independent of estrogen receptors.
In: Scientific Reports, Vol. 11, No. 1, 8313
2020
Spix, Barbara; Chao, Yu-Kai; Abrahamian, Carla; Chen, Cheng-Chang und Grimm, Christian
(February 2020):
TRPML Cation Channels in Inflammation and Immunity.
In: Frontiers in Immunology, Vol. 11, 225: pp. 1-9
[PDF, 747kB]