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Gruppiert nach: Dokumententyp | Veröffentlichungsdatum
Anzahl der Publikationen: 14 .

Zeitschriftenartikel

Pfizer, Jose; Assfalg-Machleidt, Irmgard; Machleidt, Werner; Schaschke, Norbert (2008): Inhibition of human μ-calpain by conformationally constrained calpastatin peptides. In: Biological Chemistry, Vol. 389, Nr. 1: S. 83-90 [PDF, 216kB]

Fernández-Montalván, Amaury; Assfalg-Machleidt, Irmgard; Pfeiler, Dietmar; Fritz, Hans; Jochum, Marianne; Machleidt, Werner (2006): μ-calpain binds to lipid bilayers via the exposed hydrophobic surface of its Ca2+-activated conformation. In: Biological Chemistry, Vol. 387, Nr. 5: S. 617-627 [PDF, 226kB]

Krol, Janna; Sato, Sumito; Rettenberger, Peter; Assfalg-Machleidt, Irmgard; Schmitt, Manfred; Magdolen, Viktor; Magdolen, Ulla (2003): Novel bi- and trifunctional inhibitors of tumor-associated proteolytic systems. In: Biological Chemistry, Vol. 384, Nr. 7: S. 1085-1096 [PDF, 313kB]

Hoffmann, D.; Assfalg-Machleidt, Irmgard; Nitschko, H.; Helm, K. von der; Koszinowski, U.; Machleidt, Werner (2003): Rapid enzymatic test for phenotypic HIV protease drug resistance. In: Biological Chemistry, Vol. 384, Nr. 7: S. 1109-1117 [PDF, 128kB]

Gil-Parrado, S.; Assfalg-Machleidt, Irmgard; Fiorino, F.; Deluca, D.; Pfeiler, D.; Schaschke, N.; Moroder, L.; Machleidt, Werner (2003): Calpastatin exon 1B-derived peptide, a selective inhibitor of calpain: Enhancing cell permeability by conjugation with penetratin. In: Biological Chemistry, Vol. 384, Nr. 3: S. 395-402 [PDF, 128kB]

Schaschke, Norbert; Deluca, Dominga; Assfalg-Machleidt, Irmgard; Höhneke, Clara; Sommerhoff, Christian P.; Machleidt, Werner (2002): Epoxysuccinyl peptide-derived cathepsin B inhibitors: Modulating membrane permeability by conjugation with the C-terminal heptapeptide segment of penetratin. In: Biological Chemistry, Vol. 383, Nr. 5: S. 849-852 [PDF, 121kB]

Gabrijelcic-Geiger, Dusica; Mentele, Reinhard; Meisel, Barbara; Hinz, Heide; Assfalg-Machleidt, Irmgard; Machleidt, Werner; Möller, Achim; Auerswald, Ennes A. (2001): Human μ-calpain: Simple isolation from erythrocytes and characterization of autolysis fragments. In: Biological Chemistry, Vol. 382, Nr. 12: S. 1733-1737 [PDF, 188kB]

García Diaz, Beatriz; Gross, Stefan; Assfalg-Machleidt, Irmgard; Pfeiler, Dietmar; Gollmitzer, Nicole; Gabrijelcic-Geiger, Dusica; Stubbs, Milton T.; Fritz, Hans; Auerswald, Ennes A.; Machleidt, Werner (2001): Cystatins as calpain inhibitors: Engineered chicken cystatin- and stefin B-kininogen domain 2 hybrids support a cystatin-like mode of interaction with the catalytic subunit of μ-calpain. In: Biological Chemistry, Vol. 382, Nr. 1: S. 97-107 [PDF, 219kB]

Machleidt, W.; Assfalg-Machleidt, Irmgard; Jochum, Marianne; Jänicke, F.; Schmitt, M. (1992): Lysosomal cysteine proteinases as mediators of inflammation and tumor spread. Control of their extracellular proteolytic activity. In: Fibronolysis, Vol. 6, Nr. Sup.4: S. 125-129 [PDF, 1MB]

Billing, A.; Fröhlich, D.; Assfalg-Machleidt, Irmgard; Machleidt, W.; Jochum, Marianne (1991): Proteolysis of defensive proteins in peritonitis exudate. Pathobiochemical aspects and therapeutical approach. In: Biomedica biochimica acta, Vol. 50, Nr. 4-6: S. 399-402 [PDF, 794kB]

Assfalg-Machleidt, Irmgard; Jochum, Marianne; Nast-Kolb, Dieter; Siebeck, Matthias; Billing, Arend; Joka, Theo; Rothe, Gregor; Valet, Günter; Zauner, Rita; Scheuber, Heinz- Peter; Machleidt, Werner (1990): Cathepsin B - indicator for the release of lysosomal cyasteine proteinases in severe trauma and inflammation. In: Biological chemistry Hoppe-Seyler, Vol. 371, Nr. Supple: S. 211-222 [PDF, 1MB]

Assfalg-Machleidt, Irmgard; Jochum, Marianne; Klaubert, W.; Inthorn, D.; Machleidt, W. (1988): Enzymatically active cathepsin B dissociating from its inhibitor complexes is elevated in blood plasma of patients wih septic shock and some malignant tumors. In: Biological chemistry Hoppe-Seyler, Vol. 369, Nr. Suppl.: S. 263-269

Buchbeitrag

Machleidt, W.; Assfalg-Machleidt, Irmgard; Billing, A.; Fröhlich, D.; Jochum, Marianne; Joka, T.; Nast-Kolb, Dieter (1993): The role of lysosomal cysteine proteinases as markers of macrophage activation and as non-specific mediators of inflammation. In: Faist, E.; Meakins, J.; Schildberg, F. W. (Hrsg.): Host Defence Dysfunction in Trauma, Shock and Sepsis. Berlin, Heidelberg: Springer. S. 459-463 [PDF, 1MB]

Konferenzbeitrag

Jochum, Marianne; Assfalg-Machleidt, Irmgard; Inthorn, D.; Nast-Kolb, Dieter; Waydhas, Christian; Fritz, Hans (1990): Leukozytäre Proteinasen und Hämostasestörung bei der Sepsis. 32. Hamburger Symposium über Blutgerinnung, 26. - 27. Mai 1989, Hamburg. [PDF, 1MB]

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