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Gruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 12
2022
Bluemel, Oliver; Pavlistic, Andraz; Likozar, Blaz; Rodrigues, Miguel A.; Geraldes, Vitor; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
Computational fluid dynamic simulations of temperature, cryoconcentration, and stress time during large-scale freezing and thawing of monoclonal antibody solutions.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 177: S. 107-112
Bluemel, Oliver; Anuschek, Moritz; Buecheler, Jakob W.; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - Part 1: Higher molecular weight species and subvisible particle formation.
In: International Journal of Pharmaceutics: X, Bd. 4, 100108
Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
The effect of mAb and excipient cryoconcentration on long-term frozen storage stability - part 2: Aggregate formation and oxidation.
In: International Journal of Pharmaceutics: X, Bd. 4, 100109
Bluemel, Oliver; Rodrigues, A. Miguel; Buecheler, W. Jakob; Geraldes, Vitor; Hoelzl, Georg; Hauptmann, Astrid; Bechtold-Peters, Karoline und Friess, Wolfgang
(2022):
Evaluation of Two Novel Scale-Down Devices for Testing Monoclonal Antibody Aggregation During Large-Scale Freezing.
In: Journal of Pharmaceutical Sciences, Bd. 111, Nr. 7: S. 1973-1983
2021
Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Frieß, Wolfgang
(2021):
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients.
In: Pharmaceutical research, Bd. 38, Nr. 11: S. 1977-1989
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Bluemel, Oliver; Buecheler, Jakob W.; Hauptmann, Astrid; Hoelzl, Georg; Bechtold-Peters, Karoline und Frieß, Wolfgang
(2021):
Scaling Down Large-Scale Thawing of Monoclonal Antibody Solutions: 3D Temperature Profiles, Changes in Concentration, and Density Gradients.
In: Pharmaceutical Research, Bd. 38, Nr. 11: S. 1977-1989
2020
Bluemel, Oliver; Buecheler, Jakob W.; Rodrigues, Miguel A.; Geraldes, Vitor; Hoelzl, Georg; Bechtold-Peters, Karoline und Friess, Wolfgang
(2020):
Cryoconcentration and 3D Temperature Profiles During Freezing of mAb Solutions in Large-Scale PET Bottles and a Novel Scale-Down Device.
In: Pharmaceutical Research, Bd. 37, Nr. 9, 179
2018
Saller, Verena; Hediger, Constanze; Matilainen, Julia; Grauschopf, Ulla; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2018):
Influence of particle shedding from silicone tubing on antibody stability.
In: Journal of Pharmacy and Pharmacology, Bd. 70, Nr. 5: S. 675-685
2017
Saller, Verena; Matilainen, Julia; Rothkopf, Christian; Serafin, Daniel; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2017):
Preservative loss from silicone tubing during filling processes.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 112: S. 109-118
2016
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2016):
Optimization of the bake-on siliconization of cartridges. Part I: Optimization of the spray-on parameters.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 104: S. 200-215
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian; Vetter, Florian; Müller, Christoph; Bracher, Franz und Friess, Wolfgang
(2016):
Optimization of the bake-on siliconization of cartridges. Part II: Investigations into burn-in time and temperature.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 105: S. 209-222
Funke, Stefanie; Matilainen, Julia; Nalenz, Heiko; Bechtold-Peters, Karoline; Mahler, Hanns-Christian und Friess, Wolfgang
(2016):
Silicone Migration From Baked-on Silicone Layers. Particle Characterization in Placebo and Protein Solutions.
In: Journal of Pharmaceutical Sciences, Bd. 105, Nr. 12: S. 3520-3531