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Anzahl der Publikationen: 19
Zeitschriftenartikel
Vos, Winnie G.; van Os, Bram W.; den Toom, Myrthe; Beckers, Linda; van Roomen, Cindy P. A. A.; van Tiel, Claudia M.; Mohapatra, Bhopal C.; Band, Hamid; Nitz, Katrin; Weber, Christian; Atzler, Dorothee; de Winther, Menno P. J.; Bosmans, Laura A.; Lutgens, Esther und Seijkens, Tom T. P.
(2024):
T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.
In: Frontiers in Immunology, Bd. 15, 1297893
[PDF, 3MB]
van Os, Bram W 
ORCID: https://orcid.org/0000-0002-2327-0527; Vos, Winnie G; Bosmans, Laura A; van Tiel, Claudia M; Lith, Sanne C; den Toom, Myrthe S; Beckers, Linda; Levels, Johannes H M; van Wouw, Suzanne A E; Zelcer, Noam; Zaal, Esther A; Berkers, Celia R; van der Lest, Chris H A; Helms, J Bernd; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Atzler, Dorothee; de Winther, Menno P J; Baardman, Jeroen; Lutgens, Esther und Ketelhuth, Daniel FJ
(2023):
Hyperlipidaemia elicits an atypical, T helper 1–like CD4+ T-cell response: a key role for very low-density lipoprotein.
In: European Heart Journal Open, Bd. 3, Nr. 2
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-2327-0527; Vos, Winnie G; Bosmans, Laura A; van Tiel, Claudia M; Lith, Sanne C; den Toom, Myrthe S; Beckers, Linda; Levels, Johannes H M; van Wouw, Suzanne A E; Zelcer, Noam; Zaal, Esther A; Berkers, Celia R; van der Lest, Chris H A; Helms, J Bernd; Weber, Christian ORCID: https://orcid.org/0000-0003-4610-8714; Atzler, Dorothee; de Winther, Menno P J; Baardman, Jeroen; Lutgens, Esther und Ketelhuth, Daniel FJ
(2023):
Hyperlipidaemia elicits an atypical, T helper 1–like CD4+ T-cell response: a key role for very low-density lipoprotein.
In: European Heart Journal Open, Bd. 3, Nr. 2
[PDF, 2MB]
Bosmans, Laura A.; Tiel, Claudia M. van; Aarts, Suzanne A. B. M.; Willemsen, Lisa; Baardman, Jeroen; Os, Bram W. van; Toom, Myrthe den; Beckers, Linda; Ahern, David J.; Levels, Johannes H. M.; Jongejan, Aldo; Moerland, Perry D.; Verberk, Sanne G. S.; Bossche, Jan van den; Winther, Menno M. P. J. de; Weber, Christian; Atzler, Dorothee; Monaco, Claudia; Gerdes, Norbert; Shami, Annelie und Lutgens, Esther
(2022):
Myeloid CD40 deficiency reduces atherosclerosis by impairing macrophages' transition into a pro-inflammatory state.
In: Cardiovascular Research, Bd. 119, Nr. 5: S. 1146-1160
[PDF, 1MB]
Kane, Jamie; Jansen, Matthijs; Hendrix, Sebastian; Bosmans, Laura A.; Beckers, Linda; Tiel, Claudia van; Gijbels, Marion; Zelcer, Noam; Vries, Carlie J. de; Hundelshausen, Philipp von; Vervloet, Marc; Eringa, Ed; Horrevoets, Anton J.; Royen, Niels van und Lutgens, Esther
(2022):
Anti-Galectin-2 Antibody Treatment Reduces Atherosclerotic Plaque Size and Alters Macrophage Polarity.
In: Thrombosis and Haemostasis, Bd. 122, Nr. 6: S. 1047-1057
Aarts, Suzanne A. B. M.; Seijkens, Tom T. P.; Kusters, Pascal J. H.; van Tiel, Claudia M.; Reiche, Myrthe E.; den Toom, Myrthe; Beckers, Linda; van Roomen, Cindy P. A. A.; de Winther, Menno P. J.; Kooij, Gijs und Lutgens, Esther
(2019):
Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis.
In: Journal of Pathology, Bd. 247, Nr. 4: S. 471-480
Aarts, Suzanne; Reiche, Myrthe; Toom, Myrthe den; Gijbels, Marion; Beckers, Linda; Gerdes, Norbert und Lutgens, Esther
(2019):
Depletion of CD40 on CD11c(+) cells worsens the metabolic syndrome and ameliorates hepatic inflammation during NASH.
In: Scientific Reports, Bd. 9, 14702
[PDF, 4MB]
Beldman, Thijs J.; Malinova, Tsveta S.; Desclos, Emilie; Grootemaat, Anita E.; Misiak, Aresh L. S.; van der Velden, Saskia; van Roomen, Cindy P. A. A.; Beckers, Linda; van Veen, Henk A.; Krawczyk, Przemyslaw M.; Hoebe, Ron A.; Sluimer, Judith C.; Neele, Annette E.; de Winther, Menno P. J.; van der Wel, Nicole N.; Lutgens, Esther; Mulder, Willem J. M.; Huveneers, Stephan und Kluza, Ewelina
(2019):
Nanoparticle-Aided Characterization of Arterial Endothelial Architecture during Atherosclerosis Progression and Metabolic Therapy.
In: ACS Nano, Bd. 13, Nr. 12: S. 13759-13774
Seijkens, Tom T. P.; Tiel, Claudia M. van; Kusters, Pascal J. H.; Atzler, Dorothee; Soehnlein, Oliver; Zarzycka, Barbara; Aarts, Suzanne A. B. M.; Lameijer, Marnix; Gijbels, Marion J.; Beckers, Linda; Toom, Myrthe den; Slutter, Bram; Kuiper, Johan; Duchene, Johan; Aslani, Maria; Megens, Remco T. A.; Veer, Cornelis van 't; Kooij, Gijs; Schrijver, Roy; Hoeksema, Marten A.; Boon, Louis; Fay, Francois; Tang, Jun; Baxter, Samantha; Jongejan, Aldo; Moerland, Perry D.; Vriend, Gert; Bleijlevens, Boris; Fisher, Edward A.; Duivenvoorden, Raphael; Gerdes, Norbert; Winther, Menno P. J. de; Nicolaes, Gerry A.; Mulder, Willem J. M.; Weber, Christian und Lutgens, Esther
(2018):
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
In: Journal of the American College of Cardiology, Bd. 71, Nr. 5: S. 527-542
Kusters, Pascal J. H.; Seijkens, Tom T. P.; Beckers, Linda; Lievens, Dirk; Winkels, Holger; Waard, Vivian de; Duijvestijn, Adriaan; Liljeqvist, Moritz Lindquist; Roy, Joy; Daugherty, Alan; Newby, Andrew; Gerdes, Norbert und Lutgens, Esther
(2018):
CD40L Deficiency Protects Against Aneurysm Formation.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 5: S. 1076-1085
[PDF, 1MB]
Berg, Susan M. van den; Dam, Andrea D. van; Kusters, Pascal J. H.; Beckers, Linda; Toom, Myrthe den; Velden, Saskia van der; Bossche, Jan van den; Die, Irma van; Boon, Mariette R.; Rensen, Patrick C. N.; Lutgens, Esther und Winther, Menno P. J. de
(2017):
Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.
In: Journal of Molecular Endocrinology, Bd. 59, Nr. 3: S. 245-255
Kusters, Pascal; Seijkens, Tom; Bürger, Christina; Legein, Bart; Winkels, Holger; Gijbels, Marion; Barthels, Christian; Bennett, Remy; Beckers, Linda; Atzler, Dorothee; Biessen, Erik; Brocker, Thomas; Weber, Christian; Gerdes, Norbert und Lutgens, Esther
(2017):
Constitutive CD40 Signaling in Dendritic Cells Limits Atherosclerosis by Provoking Inflammatory Bowel Disease and Ensuing Cholesterol Malabsorption.
In: American Journal of Pathology, Bd. 187, Nr. 12: S. 2912-2919
Aarts, Suzanne A. B. M.; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Pol, Susanne M. A. van der; Zarzycka, Barbara; Heijnen, Priscilla D. A. M.; Beckers, Linda; Toom, Myrthe den; Gijbels, Marion J. J.; Boon, Louis; Weber, Christian; Vries, Helga E. de; Nicolaes, Gerry A. F.; Dijkstra, Christine D.; Kooij, Gijs und Lutgens, Esther
(2017):
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.
In: Journal of Neuroinflammation
14:105
[PDF, 3MB]
Winkels, Holger; Meiler, Svenja; Smeets, Esther; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Rinne, Petteri; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Bossche, Jan van den; Holdt, Lesca M.; Megens, Remco T. A.; Schmitt, Martin M.; Winther, Menno de; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD70 limits atherosclerosis and promotes macrophage function.
In: Thrombosis and Haemostasis, Bd. 117, Nr. 1: S. 164-175
Winkels, Holger; Meiler, Svenja; Lievens, Dirk; Engel, David; Spitz, Charlotte; Bürger, Christina; Beckers, Linda; Dandl, Angelika; Reim, Sigrid; Ahmadsei, Maiwand; Hartwig, Helene; Holdt, Lesca M.; Hristov, Michael; Megens, Remco T. A.; Schmitt, Martin M.; Biessen, Eric A.; Borst, Jannie; Faussner, Alexander; Weber, Christian; Lutgens, Esther und Gerdes, Norbert
(2017):
CD27 co-stimulation increases the abundance of regulatory T cells and reduces atherosclerosis in hyperlipidaemic mice.
In: European Heart Journal, Bd. 38, Nr. 48:
3590-U42
Berg, Susan M. van den; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Beckers, Linda; Toom, Myrthe; den Smeets, Esther; Levels, Johannes; Winther, Menno P. J. de und Lutgens, Esther
(2016):
Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow.
In: FASEB Journal, Bd. 30, Nr. 5: S. 1779-1788
Meiler, Svenja; Smeets, Esther; Winkels, Holger; Shami, Annelie; Pascutti, Maria Fernanda; Nolte, Martijn A.; Beckers, Linda; Weber, Christian; Gerdes, Norbert und Lutgens, Esther
(2016):
Constitutive GITR Activation Reduces Atherosclerosis by Promoting Regulatory CD4(+) T-Cell ResponsesBrief Report.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 9: S. 1748-1752
Gerdes, Norbert; Seijkens, Tom; Lievens, Dirk; Kuijpers, Marijke J. E.; Winkels, Holger; Projahn, Delia; Hartwig, Helene; Beckers, Linda; Megens, Remco T. A.; Boon, Louis; Noelle, Randolph J.; Soehnlein, Oliver; Heemskerk, Johan W. M.; Weber, Christian und Lutgens, Esther
(2016):
Platelet CD40 Exacerbates Atherosclerosis by Transcellular Activation of Endothelial Cells and Leukocytes.
In: Arteriosclerosis thrombosis and Vascular Biology, Bd. 36, Nr. 3: S. 482-490
Braster, Quinte; Roig, Carlos Silvestre; Hartwig, Helene; Beckers, Linda; den Toom, Myrthe; Döring, Yvonne; Deemen, Mat J.; Lutgens, Esther und Soehnlein, Oliver
(2016):
Inhibition of NET Release Fails to Reduce Adipose Tissue Inflammation in Mice.
In: PLOS ONE 11(10), e0163922 [PDF, 1MB]
In: PLOS ONE 11(10), e0163922 [PDF, 1MB]
Hartwig, Helene; Silvestre-Roig, Carlos; Hendrikse, Jeffrey; Beckers, Linda; Paulin, Nicole; Heiden, Kim van der; Braster, Quinte; Drechsler, Maik; Daemen, Mat J.; Lutgens, Esther und Soehnlein, Oliver
(2015):
Atherosclerotic Plaque Destabilization in Mice: A Comparative Study.
In: PLOS ONE 10(10), e0141019 [PDF, 2MB]
In: PLOS ONE 10(10), e0141019 [PDF, 2MB]