Anzahl der Publikationen: 10
Zeitschriftenartikel
Schmidt, Henrik; Raj, Timsse; O'Neill, Thomas J.; Muschaweckh, Andreas; Giesert, Florian; Negraschus, Arlinda; Hoefig, Kai P.; Behrens, Gesine; Esser, Lena; Baumann, Christina; Feederle, Regina; Plaza-Sirvent, Carlos; Geerlof, Arie; Gewies, Andreas; Isay, Sophie E.; Ruland, Juergen; Schmitz, Ingo; Wurst, Wolfgang; Korn, Thomas; Krappmann, Daniel und Heissmeyer, Vigo
(2023):
Unrestrained cleavage of Roquin-1 by MALT1 induces spontaneous T cell activation and the development of autoimmunity.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 120, Nr. 48, e2309205120
[PDF, 2MB]
Hoefig, Kai P.; Reim, Alexander; Gallus, Christian; Wong, Elaine H.; Behrens, Gesine; Conrad, Christine; Xu, Meng; Kifinger, Lisa; Ito-Kureha, Taku; Defourny, Kyra A. Y.; Geerlof, Arie; Mautner, Josef; Hauck, Stefanie M.; Baumjohann, Dirk; Feederle, Regina; Mann, Matthias; Wierer, Michael; Glasmacher, Elke und Heissmeyer, Vigo
(2021):
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
In: Nature Communications, Bd. 12, 5208
[PDF, 16MB]
Behrens, Gesine; Edelmann, Stephanie L.; Raj, Timsse; Kronbeck, Nina; Monecke, Thomas; Davydova, Elena; Wong, Elaine H.; Kifinger, Lisa; Giesert, Florian; Kirmaier, Martin E.; Hohn, Christine; de Jonge, Laura S.; Pisfil, Mariano Gonzalez; Fu, Mingui; Theurich, Sebastian; Feske, Stefan; Kawakami, Naoto; Wurst, Wolfgang; Niessing, Dierk und Heissmeyer, Vigo
(2021):
Disrupting Roquin-1 interaction with Regnase-1 induces autoimmunity and enhances antitumor responses.
In: Nature Immunology, Bd. 22, Nr. 12: S. 1563-1576
Hoefig, Kai P.; Reim, Alexander; Gallus, Christian; Wong, Elaine H.; Behrens, Gesine; Conrad, Christine; Xu, Meng; Kifinger, Lisa; Ito-Kureha, Taku; Defourny, Kyra A. Y.; Geerlof, Arie; Mautner, Josef; Hauck, Stefanie M.; Baumjohann, Dirk; Feederle, Regina; Mann, Matthias; Wierer, Michael; Glasmacher, Elke und Heissmeyer, Vigo
(2021):
Defining the RBPome of primary T helper cells to elucidate higher-order Roquin-mediated mRNA regulation.
In: Nature Communications, Bd. 12, Nr. 1, 5208
Gamm, Matthias von; Schaub, Annalisa; Jones, Alisha N.; Wolf, Christine; Behrens, Gesine; Lichti, Johannes; Essig, Katharina; Macht, Anna; Pircher, Joachim; Ehrlich, Andreas; Davari, Kathrin; Chauhan, Dhruv; Busch, Benjamin; Wurst, Wolfgang; Feederle, Regina; Feuchtinger, Annette; Tschoep, Matthias H.; Friedel, Caroline C.; Hauck, Stefanie M.; Sattler, Michael; Geerlof, Arie; Hornung, Veit; Heissmeyer, Vigo; Schulz, Christian; Heikenwalder, Mathias und Glasmacher, Elke
(2019):
Immune homeostasis and regulation of the interferon pathway require myeloid-derived Regnase-3.
In: Journal of Experimental Medicine, Bd. 216, Nr. 7: S. 1700-1723
[PDF, 6MB]
Rehage, Nina; Davydova, Elena; Conrad, Christine; Behrens, Gesine; Maiser, Andreas; Stehklein, Jenny E.; Brenner, Sven; Klein, Juliane; Jeridi, Aicha; Hoffmann, Anne; Lee, Eunhae; Dianzani, Umberto; Willemsen, Rob; Feederle, Regina; Reiche, Kristin; Hackermüller, Jörg; Leonhardt, Heinrich; Sharma, Sonia; Niessing, Dierk und Heissmeyer, Vigo
(2018):
Binding of NUFIP2 to Roquin promotes recognition and regulation of ICOS mRNA.
In: Nature Communications, Bd. 9, 299
[PDF, 3MB]
Essig, Katharina; Kronbeck, Nina; Guimaraes, Joao C.; Lohs, Claudia; Schlundt, Andreas; Hoffmann, Anne; Behrens, Gesine; Brenner, Sven; Kowalska, Joanna; Lopez-Rodriguez, Cristina; Jemielity, Jacek; Holtmann, Helmut; Reiche, Kristin; Hackermüller, Jörg; Sattler, Michael; Zavolan, Mihaela und Heissmeyer, Vigo
(2018):
Roquin targets mRNAs in a 3 '-UTR-specific manner by different modes of regulation.
In: Nature Communications, Bd. 9, 3810
[PDF, 3MB]
Behrens, Gesine; Winzen, Reinhard; Rehage, Nina; Dörrie, Anneke; Barsch, Monika; Hoffmann, Anne; Hackermüller, Jörg; Tiedje, Christopher; Heissmeyer, Vigo und Holtmann, Helmut
(2018):
A translational silencing function of MCPIP1/Regnase-1 specified by the target site context.
In: Nucleic Acids Research, Bd. 46, Nr. 8: S. 4256-4270
[PDF, 2MB]
Essig, Katharina; Hu, Desheng; Guimaraes, Joao C.; Alterauge, Dominik; Edelmann, Stephanie; Raj, Timsse; Kranich, Jan; Behrens, Gesine; Heiseke, Alexander; Floess, Stefan; Klein, Juliane; Maiser, Andreas; Marschall, Susan; Hrabe de Angelis, Martin; Leonhardt, Heinrich; Calkhoven, Cornelis F.; Noessner, Elfriede; Brocker, Thomas; Huehn, Jochen; Krug, Anne B.; Zavolan, Mihaela; Baumjohann, Dirk und Heissmeyer, Vigo
(2017):
Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells.
In: Immunity, Bd. 47, Nr. 6: S. 1067-1082
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