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Anzahl der Publikationen: 16
Zeitschriftenartikel
Lorenzini, Theo 
ORCID: https://orcid.org/0000-0003-3377-032X; Cadilha, Bruno L. ORCID: https://orcid.org/0000-0001-7045-3898; Obeck, Hannah; Benmebarek, Mohamed-Reda; Märkl, Florian ORCID: https://orcid.org/0000-0003-4285-0380; Michaelides, Stefanos; Strzalkowski, Thaddäus; Briukhovetska, Daria; Müller, Philipp Jie; Nandi, Sayantan; Winter, Pia; Majed, Lina; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Seifert, Matthias ORCID: https://orcid.org/0000-0002-6581-6196; Rausch, Svenja; Feuchtinger, Tobias ORCID: https://orcid.org/0000-0002-8517-9681; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2023):
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy.
In: British Journal of Cancer, Bd. 129, Nr. 4: S. 696-705
[PDF, 2MB]
ORCID: https://orcid.org/0000-0003-3377-032X; Cadilha, Bruno L. ORCID: https://orcid.org/0000-0001-7045-3898; Obeck, Hannah; Benmebarek, Mohamed-Reda; Märkl, Florian ORCID: https://orcid.org/0000-0003-4285-0380; Michaelides, Stefanos; Strzalkowski, Thaddäus; Briukhovetska, Daria; Müller, Philipp Jie; Nandi, Sayantan; Winter, Pia; Majed, Lina; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Seifert, Matthias ORCID: https://orcid.org/0000-0002-6581-6196; Rausch, Svenja; Feuchtinger, Tobias ORCID: https://orcid.org/0000-0002-8517-9681; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2023):
Rational design of PD-1-CD28 immunostimulatory fusion proteins for CAR T cell therapy.
In: British Journal of Cancer, Bd. 129, Nr. 4: S. 696-705
[PDF, 2MB]
Gottschlich, Adrian; Thomas, Moritz; Gruenmeier, Ruth; Lesch, Stefanie; Rohrbacher, Lisa; Igl, Veronika; Briukhovetska, Daria; Benmebarek, Mohamed-Reda; Vick, Binje; Dede, Sertac; Mueller, Katharina; Xu, Tao; Dhoqina, Dario; Maerkl, Florian; Robinson, Sophie; Sendelhofert, Andrea; Schulz, Heiko; Umut, Oeykue; Kavaka, Vladyslav; Tsiverioti, Christina Angeliki; Carlini, Emanuele; Nandi, Sayantan; Strzalkowski, Thaddaeus; Lorenzini, Theo; Stock, Sophia; Mueller, Philipp Jie; Doerr, Janina; Seifert, Matthias; Cadilha, Bruno L.; Brabenec, Ruben; Roeder, Natalie; Rataj, Felicitas; Nueesch, Manuel; Modemann, Franziska; Wellbrock, Jasmin; Fiedler, Walter; Kellner, Christian; Beltran, Eduardo; Herold, Tobias; Paquet, Dominik; Jeremias, Irmela; von Baumgarten, Louisa; Endres, Stefan; Subklewe, Marion; Marr, Carsten und Kobold, Sebastian
(2023):
Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
In: Nature Biotechnology, Bd. 41, Nr. 11:
1618-+
[PDF, 7MB]
Seifert, Matthias; Benmebarek, Mohamed-Reda; Briukhovetska, Daria; Märkl, Florian; Dörr, Janina; Cadilha, Bruno L.; Jobst, Jakob; Stock, Sophia ORCID: https://orcid.org/0000-0002-5072-5013; Andreu-Sanz, David; Lorenzini, Theo; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Oner, Arman; Obeck, Hannah; Majed, Lina; Dhoqina, Dario; Feinendegen, Manouk; Gottschlich, Adrian ORCID: https://orcid.org/0000-0002-2898-4182; Zhang, Jin; Schindler, Ulrike; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Impact of the selective A2(A)R and A2(B)R dual antagonist AB928/etrumadenant on CAR T cell function.
In: British Journal of Cancer, Bd. 127, Nr. 12: S. 2175-2185
[PDF, 845kB]
ORCID: https://orcid.org/0000-0002-5072-5013; Andreu-Sanz, David; Lorenzini, Theo; Grünmeier, Ruth ORCID: https://orcid.org/0000-0002-9044-3600; Oner, Arman; Obeck, Hannah; Majed, Lina; Dhoqina, Dario; Feinendegen, Manouk; Gottschlich, Adrian ORCID: https://orcid.org/0000-0002-2898-4182; Zhang, Jin; Schindler, Ulrike; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Impact of the selective A2(A)R and A2(B)R dual antagonist AB928/etrumadenant on CAR T cell function.
In: British Journal of Cancer, Bd. 127, Nr. 12: S. 2175-2185
[PDF, 845kB]
Stock, Sophia ORCID: https://orcid.org/0000-0002-5072-5013; Benmebarek, Mohamed-Reda ORCID: https://orcid.org/0000-0002-1201-7067; Kluever, Anna-Kristina ORCID: https://orcid.org/0000-0001-6246-6082; Darowski, Diana ORCID: https://orcid.org/0000-0002-8778-7920; Jost, Christian ORCID: https://orcid.org/0000-0002-4169-5879; Stubenrauch, Kay-Gunnar; Benz, Joerg; Freimoser-Grundschober, Anne ORCID: https://orcid.org/0000-0001-5715-3639; Moessner, Ekkehard; Umana, Pablo; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
In: Journal for ImmunoTherapy of Cancer, Bd. 10, Nr. 7, e005054
[PDF, 17MB]
ORCID: https://orcid.org/0000-0002-5072-5013; Benmebarek, Mohamed-Reda ORCID: https://orcid.org/0000-0002-1201-7067; Kluever, Anna-Kristina ORCID: https://orcid.org/0000-0001-6246-6082; Darowski, Diana ORCID: https://orcid.org/0000-0002-8778-7920; Jost, Christian ORCID: https://orcid.org/0000-0002-4169-5879; Stubenrauch, Kay-Gunnar; Benz, Joerg; Freimoser-Grundschober, Anne ORCID: https://orcid.org/0000-0001-5715-3639; Moessner, Ekkehard; Umana, Pablo; Subklewe, Marion ORCID: https://orcid.org/0000-0001-9154-9469; Endres, Stefan ORCID: https://orcid.org/0000-0002-4703-537X; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2022):
Chimeric antigen receptor T cells engineered to recognize the P329G-mutated Fc part of effector-silenced tumor antigen-targeting human IgG1 antibodies enable modular targeting of solid tumors.
In: Journal for ImmunoTherapy of Cancer, Bd. 10, Nr. 7, e005054
[PDF, 17MB]
Dezfouli, Ali Bashiri; Yazdi, Mina; Benmebarek, Mohamed-Reda; Schwab, Melissa; Michaelides, Stefanos; Micciche, Arianna; Geerts, Dirk; Stangl, Stefan; Klapproth, Sarah; Wagner, Ernst; Kobold, Sebastian und Multhoff, Gabriele
(2022):
CAR T Cells Targeting Membrane-Bound Hsp70 on Tumor Cells Mimic Hsp70-Primed NK Cells.
In: Frontiers in Immunology, Bd. 13, 883694
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
ORCID: https://orcid.org/0000-0001-7594-7280; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter ORCID: https://orcid.org/0000-0002-4528-8357 und Kobold, Sebastian ORCID: https://orcid.org/0000-0002-5612-4673
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35: S. 2243-2257
[PDF, 5MB]
Schwerdtfeger, Melanie; Benmebarek, Mohamed-Reda; Endres, Stefan; Subklewe, Marion; Desiderio, Vincenzo und Kobold, Sebastian
(2021):
Chimeric Antigen Receptor-Modified T Cells and T Cell-Engaging Bispecific Antibodies: Different Tools for the Same Job.
In: Current hematologic malignancy reports, Bd. 16, Nr. 2: S. 218-233
[PDF, 1MB]
Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Herrmann, Monika; Lesch, Stefanie; Schmitt, Saskia; Stoiber, Stefan; Darwich, Abbass; Augsberger, Christian; Brauchle, Bettina; Rohrbacher, Lisa; Oner, Arman; Seifert, Matthias; Schwerdtfeger, Melanie; Gottschlich, Adrian; Rataj, Felicitas; Fenn, Nadja C.; Klein, Christian; Subklewe, Marion; Endres, Stefan; Hopfner, Karl-Peter und Kobold, Sebastian
(2021):
A modular and controllable T cell therapy platform for acute myeloid leukemia.
In: Leukemia, Bd. 35, Nr. 8: S. 2243-2257
Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Dorman, Klara; Oner, Arman; Lorenzini, Theo; Obeck, Hannah; Vaenttinen, Mira; Di Pilato, Mauro; Pruessmann, Jasper N.; Stoiber, Stefan; Duc, Huynh; Maerkl, Florian; Seifert, Matthias; Manske, Katrin; Suarez-Gosalvez, Javier; Zeng, Yi; Lesch, Stefanie; Karches, Clara H.; Heise, Constanze; Gottschlich, Adrian; Thomas, Moritz; Marr, Carsten; Zhang, Jin; Pandey, Dharmendra; Feuchtinger, Tobias; Subklewe, Marion; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
In: Science Advances, Bd. 7, Nr. 24, eabi5781
Darwich, Abbass; Silvestri, Alessandra; Benmebarek, Mohamed-Reda; Mouries, Juliette; Cadilha, Bruno; Melacarne, Alessia; Morelli, Lapo; Supino, Domenico; Taleb, Alexandre; Obeck, Hannah; Sustmann, Claudio; Losurdo, Agnese; Masci, Giovanna; Curigliano, Giuseppe; Kobold, Sebastian; Penna, Giuseppe und Rescigno, Maria
(2021):
Paralysis of the cytotoxic granule machinery is a new cancer immune evasion mechanism mediated by chitinase 3-like-1.
In: Journal for Immunotherapy of Cancer, Bd. 9, Nr. 11, e003224
Lesch, Stefanie; Blumenberg, Viktoria; Stoiber, Stefan; Gottschlich, Adrian; Ogonek, Justyna; Cadilha, Bruno L.; Dantes, Zahra; Rataj, Felicitas; Dorman, Klara; Lutz, Johannes; Karches, Clara H.; Heise, Constanze; Kurzay, Mathias; Larimer, Benjamin M.; Grassmann, Simon; Rapp, Moritz; Nottebrock, Alessia; Kruger, Stephan; Tokarew, Nicholas; Metzger, Philipp; Hoerth, Christine; Benmebarek, Mohamed-Reda; Dhoqina, Dario; Grunmeier, Ruth; Seifert, Matthias; Oener, Arman; Umut, Oyku; Joaquina, Sandy; Vimeux, Lene; Tran, Thi; Hank, Thomas; Baba, Taisuke; Huynh, Duc; Megens, Remco T. A.; Janssen, Klaus-Peter; Jastroch, Martin; Lamp, Daniel; Ruehland, Svenja; Di Pilato, Mauro; Pruessmann, Jasper N.; Thomas, Moritz; Marr, Carsten; Ormanns, Steffen; Reischer, Anna; Hristov, Michael; Tartour, Eric; Donnadieu, Emmanuel; Rothenfusser, Simon; Duewell, Peter; Konig, Lars M.; Schnurr, Max; Subklewe, Marion; Liss, Andrew S.; Halama, Niels; Reichert, Maximilian; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
In: Nature Biomedical Engineering, Bd. 5, Nr. 11
Schwerdtfeger, Melanie; Benmebarek, Mohamed-Reda; Endres, Stefan; Subklewe, Marion; Desiderio, Vincenzo und Kobold, Sebastian
(2021):
Chimeric Antigen Receptor-Modified T Cells and T Cell-Engaging Bispecific Antibodies: Different Tools for the Same Job.
In: Current Hematologic Malignancy Reports, Bd. 16, Nr. 2: S. 218-233
Lesch, Stefanie; Benmebarek, Mohamed-Reda; Cadilha, Bruno L.; Stoiber, Stefan; Subklewe, Marion; Endres, Stefan und Kobold, Sebastian
(2020):
Determinants of response and resistance to CAR T cell therapy.
In: Seminars in Cancer Biology, Bd. 65: S. 80-90
Karches, Clara H.; Benmebarek, Mohamed-Reda; Schmidbauer, Moritz L.; Kurzay, Mathias; Klaus, Richard; Geiger, Martina; Rataj, Felicitas; Cadilha, Bruno L.; Lesch, Stefanie; Heise, Constanze; Murr, Ramona; vom Berg, Johannes; Jastroch, Martin; Lamp, Daniel; Ding, Jian; Duewell, Peter; Niederfellner, Gerhard; Sustmann, Claudio; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy.
In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5890-5900
Stoiber, Stefan; Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Lesch, Stefanie; Endres, Stefan und Kobold, Sebastian
(2019):
Limitations in the Design of Chimeric Antigen Receptors for Cancer Therapy.
In: Cells, Bd. 8, Nr. 5, 472
Benmebarek, Mohamed-Reda; Karches, Clara Helke; Cadilha, Bruno Loureiro; Lesch, Stefanie; Endres, Stefan und Kobold, Sebastian
(2019):
Killing Mechanisms of Chimeric Antigen Receptor (CAR) T Cells.
In: International Journal of Molecular Sciences, Bd. 20, Nr. 6, 1283