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Anzahl der Publikationen: 21
Zeitschriftenartikel
Carnevale, Julia; Shifrut, Eric; Kale, Nupura; Nyberg, William A.; Blaeschke, Franziska; Chen, Yan Yi; Li, Zhongmei; Bapat, Sagar P.; Diolaiti, Morgan E.; O'Leary, Patrick; Vedova, Shane; Belk, Julia; Daniel, Bence; Roth, Theodore L.; Bachl, Stefanie; Anido, Alejandro Allo; Prinzing, Brooke; Ibanez-Vega, Jorge; Lange, Shannon; Haydar, Dalia; Luetke-Eversloh, Marie; Born-Bony, Maelys; Hegde, Bindu; Kogan, Scott; Feuchtinger, Tobias; Okada, Hideho; Satpathy, Ansuman T.; Shannon, Kevin; Gottschalk, Stephen; Eyquem, Justin; Krenciute, Giedre; Ashworth, Alan und Marson, Alexander
(2022):
RASA2 ablation in T cells boosts antigen sensitivity and long-term function.
In: Nature, Bd. 609, Nr. 7925: S. 174-182
Stief, Tanja A.; Kaeuferle, Theresa; Müller, Thomas R.; Doring, Michaela; Jablonowski, Lena M.; Schober, Kilian; Feucht, Judith; Dennehy, Kevin M.; Willier, Semjon; Blaeschke, Franziska; Handgretinger, Rupert; Lang, Peter; Busch, Dirk H. und Feuchtinger, Tobias
(2022):
Protective T cell receptor identification for orthotopic reprogramming of immunity in refractory virus infections.
In: Molecular Therapy, Bd. 30, Nr. 1: S. 198-208
Blaeschke, Franziska; Ortner, Eva; Stenger, Dana; Mahdawi, Jasmin; Apfelbeck, Antonia; Habjan, Nicola; Weisser, Tanja; Käuferle, Theresa; Willier, Semjon; Kobold, Sebastian und Feuchtinger, Tobias
(2022):
Design and Evaluation of TIM-3-CD28 Checkpoint Fusion Proteins to Improve Anti-CD19 CAR T-Cell Function.
In: Frontiers in Immunology, Bd. 13
[PDF, 2MB]
Willier, Semjon; Rothamel, Paula; Hastreiter, Maximilian; Wilhelm, Jonas; Stenger, Dana; Blaeschke, Franziska; Rohlfs, Meino; Kaeuferle, Theresa; Schmid, Irene; Albert, Michael H.; Binder, Vera; Subklewe, Marion; Klein, Christoph und Feuchtinger, Tobias
(2021):
CLEC12A and CD33 coexpression as a preferential target for pediatric AML combinatorial immunotherapy.
In: Blood, Bd. 137, Nr. 8: S. 1037-1049
Cordes, Nicole; Kolbe, Carolin; Lock, Dominik; Holzer, Tatjana; Althoff, Deborah; Schaefer, Daniel; Blaeschke, Franziska; Kotter, Bettina; Karitzky, Sandra; Rossig, Claudia; Cathomen, Toni; Feuchtinger, Tobias; Buerger, Iris; Assenmacher, Mario; Schaser, Thomas und Kaiser, Andrew D.
(2021):
Anti-CD19 CARs displayed at the surface of lentiviral vector particles promote transduction of target-expressing cells.
In: Molecular Therapy-Methods & Clinical Development, Bd. 21: S. 42-53
Stenger, Dana; Stief, Tanja A.; Kaeuferle, Theresa; Willier, Semjon; Rataj, Felicitas; Schober, Kilian; Vick, Binje; Lotfi, Ramin; Wagner, Beate; Grünewald, Thomas G. P.; Kobold, Sebastian; Busch, Dirk H.; Jeremias, Irmela; Blaeschke, Franziska und Feuchtinger, Tobias
(2020):
Endogenous TCR promotes in vivo persistence of CD19-CAR-T cells compared to a CRISPR/Cas9-mediated TCR knockout CAR.
In: Blood, Bd. 136, Nr. 12: S. 1407-1418
Willier, Semjon; Raedler, Johannes; Blaeschke, Franziska; Stenger, Dana; Escudero, Montserrat Pazos; Jurgeleit, Florian; Grunewald, Thomas G. P.; Binder, Vera; Schmid, Irene; Albert, Michael H.; Wolf, Armin und Feuchtinger, Tobias
(2020):
Leukemia escape in immune desert: intraocular relapse of pediatric pro-B-ALL during systemic control by CD19-CAR T cells.
In: Journal for Immunotherapy of Cancer, Bd. 8, Nr. 2, e001052
Blaeschke, Franziska; Willier, Semjon; Stenger, Dana; Lepenies, Mareike; Horstmann, Martin A.; Escherich, Gabriele; Zimmermann, Martin; Ringeling, Francisca Rojas; Canzar, Stefan; Kaeuferle, Theresa; Rohlfs, Meino; Binder, Vera; Klein, Christoph und Feuchtinger, Tobias
(2020):
Leukemia-induced dysfunctional TIM-3(+)CD4(+) bone marrow T cells increase risk of relapse in pediatric B-precursor ALL patients.
In: Leukemia, Bd. 34, Nr. 10: S. 2607-2620
Kaeuferle, Theresa; Deisenberger, Larissa; Jablonowski, Lena; Stief, Tanja A.; Blaeschke, Franziska; Willier, Semjon und Feuchtinger, Tobias
(2020):
CRISPR-Cas9-Mediated Glucocorticoid Resistance in Virus-Specific T Cells for Adoptive T Cell Therapy Posttransplantation.
In: Molecular Therapy, Bd. 28, Nr. 9: S. 1965-1973
Blaeschke, Franziska; Paul, Milan Cedric; Schuhmann, Martin Ulrich; Rabsteyn, Armin; Schröder, Christopher; Casadei, Nicolas; Matthes, Jakob; Mohr, Christopher; Lotfi, Ramin; Wagner, Beate; Kaeuferle, Theresa; Feucht, Judith; Willier, Semjon; Handgretinger, Rupert; Stevanovic, Stefan; Lang, Peter und Feuchtinger, Tobias
(2019):
Low mutational load in pediatric medulloblastoma still translates into neoantigens as targets for specific T-cell immunotherapy.
In: Cytotherapy, Bd. 21, Nr. 9: S. 973-986
Kaeuferle, Theresa; Krauss, Ramona; Blaeschke, Franziska; Willier, Semjon und Feuchtinger, Tobias
(2019):
Strategies of adoptive T -cell transfer to treat refractory viral infections post allogeneic stem cell transplantation.
In: Journal of Hematology & Oncology, Bd. 12, 13
Willier, Semjon; Cabanillas Stanchi, Karin Melanie; Have, Martina von; Binder, Vera; Blaeschke, Franziska; Feucht, Judith; Feuchtinger, Tobias und Döring, Michaela
(2019):
Efficacy, safety and feasibility of fosaprepitant for the prevention of chemotherapy-induced nausea and vomiting in pediatric patients receiving moderately and highly emetogenic chemotherapy - results of a non-interventional observation study.
In: BMC Cancer, Bd. 19, Nr. 1, 1118
Baldauf, Michaela C.; Gerke, Julia S.; Kirschner, Andreas; Blaeschke, Franziska; Effenberger, Manuel; Schober, Kilian; Rubio, Rebeca Alba; Kanaseki, Takayuki; Kiran, Merve M.; Dallmayer, Marlene; Musa, Julian; Akpolat, Nurset; Akatli, Ayse N.; Rosman, Fernando C.; Ozen, Ozlem; Sugita, Shintaro; Hasegawa, Tadashi; Sugimura, Haruhiko; Baumhoer, Daniel; Knott, Maximilian M. L.; Sannino, Giuseppina; Marchetto, Aruna; Li, Jing; Busch, Dirk H.; Feuchtinger, Tobias; Ohmura, Shunya; Orth, Martin F.; Thiel, Uwe; Kirchner, Thomas und Gruenewald, Thomas G. P.
(2018):
Systematic identification of cancer-specific MHC-binding peptides with RAVEN.
In: Oncoimmunology, Bd. 7, Nr. 9, e1481558
Blaeschke, Franziska; Stenger, Dana; Kaeuferle, Theresa; Willier, Semjon; Lotfi, Ramin; Kaiser, Andrew Didier; Assenmacher, Mario; Doering, Michaela; Feucht, Judith und Feuchtinger, Tobias
(2018):
Induction of a central memory and stem cell memory phenotype in functionally active CD4(+) and CD8(+) CAR T cells produced in an automated good manufacturing practice system for the treatment of CD19(+) acute lymphoblastic leukemia.
In: Cancer Immunology Immunotherapy, Bd. 67, Nr. 7: S. 1053-1066
Thiel, Uwe; Schober, Sebastian J.; Einspieler, Ingo; Kirschner, Andreas; Thiede, Melanie; Schirmer, David; Gall, Katja; Blaeschke, Franziska; Schmidt, Oxana; Jabar, Susanne; Ranft, Andreas; Rubio, Rebeca Alba; Dirksen, Uta; Grunewald, Thomas G. P.; Sorensen, Poul H.; Richter, Günther H. S.; Teichert von Lüttichau, Irene; Busch, Dirk H. und Burdach, Stefan E. G.
(2017):
Ewing sarcoma partial regression without GvHD by chondromodulin-I/HLA-A*02:01-specific allorestricted T cell receptor transgenic T cells.
In: Oncoimmunology, Bd. 6, Nr. 5, e1312239
Döring, Michaela; Stanchi, Karin Melanie Cabanillas; Klinker, Hartwig; Eikemeier, Melinda; Feucht, Judith; Blaeschke, Franziska; Schwarze, Carl-Philipp; Ebinger, Martin; Feuchtinger, Tobias; Handgretinger, Rupert und Heinz, Werner J.
(2017):
Posaconazole plasma concentrations in pediatric patients receiving antifungal prophylaxis during neutropenia.
In: Medical Mycology, Bd. 55, Nr. 4: S. 375-384
Döring, Michaela; Stanchi, Karin Melanie Cabanillas; Queudeville, Manon; Feucht, Judith; Blaeschke, Franziska; Schlegel, Patrick; Feuchtinger, Tobias; Lang, Peter; Müller, Ingo; Handgretinger, Rupert und Heinz, Werner J.
(2017):
Efficacy, safety and feasibility of antifungal prophylaxis with posaconazole tablet in paediatric patients after haematopoietic stem cell transplantation.
In: Journal of Cancer Research and Clinical Oncology, Bd. 143, Nr. 7: S. 1281-1292
Kirschner, Andreas; Thiede, Melanie; Blaeschke, Franziska; Richter, Günther H. S.; Gerke, Julia S.; Baldauf, Michaela C.; Grünewald, Thomas G. P.; Busch, Dirk H.; Burdach, Stefan und Thiel, Uwe
(2016):
Lysosome-associated membrane glycoprotein 1 predicts fratricide amongst T cell receptor transgenic CD8(+) T cells directed against tumor-associated antigens.
In: Oncotarget, Bd. 7, Nr. 35: S. 56584-56597
Blaeschke, Franziska; Thiel, Uwe; Kirschner, Andreas; Thiede, Melanie; Rubio, Rebeca Alba; Schirmer, David; Kirchner, Thomas; Richter, Günther H. S.; Mall, Sabine; Klar, Richard; Riddell, Stanley; Busch, Dirk H.; Krackhardt, Angela; Grunewald, Thomas G. P. und Burdach, Stefan
(2016):
Human HLA-A*02:01/CHM1(+) allo-restricted T cell receptor transgenic CD8(+) T Cells specifically inhibit Ewing sarcoma growth in vitro and in vivo.
In: Oncotarget, Bd. 7, Nr. 28: S. 43267-43280
Feucht, Judith; Kayser, Simone; Gorodezki, David; Hamieh, Mohamad; Döring, Michaela; Blaeschke, Franziska; Schlegel, Patrick; Bösmüller, Hans; Quintanilla-Fend, Leticia; Ebinger, Martin; Lang, Peter; Handgretinger, Rupert und Feuchtinger, Tobias
(2016):
T-cell responses against CD19(+) pediatric acute lymphoblastic leukemia mediated by bispecific T-cell engager (BiTE) are regulated contrarily by PD-L1 and CD80/CD86 on leukemic blasts.
In: Oncotarget, Bd. 7, Nr. 47: S. 76902-76919
Thiel, Uwe; Wawer, Angela; Luettichau, Irene von; Bender, Hans-Ulrich; Blaeschke, Franziska; Grunewald, Thomas G. P.; Steinborn, Marc; Röper, Barbara; Bonig, Halvard; Klingebiel, Thomas; Bader, Peter; Koscielniak, Ewa; Paulussen, Michael; Dirksen, Uta; Juergens, Heribert; Kolb, Hans-Jochem und Burdach, Stefan E. G.
(2016):
Bone marrow involvement identifies a subgroup of advanced Ewing sarcoma patients with fatal outcome irrespective of therapy in contrast to curable patients with multiple bone metastases but unaffected marrow.
In: Oncotarget, Bd. 7, Nr. 43: S. 70959-70968