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Anzahl der Publikationen: 24
Zeitschriftenartikel
Blume, Tanja; Filser, Severin; Sgobio, Carmelo; Peters, Finn; Neumann, Ulf; Shimshek, Derya; Saito, Takashi; Saido, Takaomi C.; Brendel, Matthias und Herms, Jochen
(22. Juli 2022):
β-secretase inhibition prevents structural spine plasticity deficits in AppNL-G-F mice.
In: Frontiers in Aging Neuroscience, Bd. 14
[PDF, 2MB]
Blume, Tanja; Deussing, Maximilian; Biechele, Gloria; Peters, Finn; Zott, Benedikt; Schmidt, Claudio; Franzmeier, Nicolai; Wind, Karin; Eckenweber, Florian; Sacher, Christian; Shi, Yuan; Ochs, Katharina; Kleinberger, Gernot; Xiang, Xianyuan; Focke, Carola; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; Baumann, Karlheinz; Adelsberger, Helmuth; Rominger, Axel; Cumming, Paul; Willem, Michael; Dorostkar, Mario M.; Herms, Jochen und Brendel, Matthias
(30. März 2022):
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
In: Frontiers in Aging Neuroscience, Bd. 14
[PDF, 7MB]
Biechele, Gloria; Monasor, Laura Sebastian; Wind, Karin; Blume, Tanja; Parhizkar, Samira; Arzberger, Thomas; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen; Lichtenthaler, Stefan F.; Haass, Christian; Tahirovic, Sabina und Brendel, Matthias
(2022):
Glitter in the Darkness? Nonfibrillar beta-Amyloid Plaque Components Significantly Impact the beta-Amyloid PET Signal in Mouse Models of Alzheimer Disease.
In: Journal of Nuclear Medicine, Bd. 63, Nr. 1: S. 117-124
Xiang, Xianyuan; Wind, Karin; Wiedemann, Thomas; Blume, Tanja; Shi, Yuan; Briel, Nils; Beyer, Leonie; Biechele, Gloria; Eckenweber, Florian; Zatcepin, Artem; Lammich, Sven; Ribicic, Sara; Tahirovic, Sabina; Willem, Michael; Deussing, Maximilian; Palleis, Carla; Rauchmann, Boris-Stephan; Gildehaus, Franz-Josef; Lindner, Simon; Spitz, Charlotte; Franzmeier, Nicolai; Baumann, Karlheinz; Rominger, Axel; Bartenstein, Peter; Ziegler, Sibylle; Drzezga, Alexander; Respondek, Gesine; Buerger, Katharina; Perneczky, Robert; Levin, Johannes; Hoeglinger, Guenter U.; Herms, Jochen; Haass, Christian und Brendel, Matthias
(2021):
Microglial activation states drive glucose uptake and FDG-PET alterations in neurodegenerative diseases.
In: Science Translational Medicine, Bd. 13, Nr. 615, eabe5640
Biechele, Gloria; Wind, Karin; Blume, Tanja; Sacher, Christian; Beyer, Leonie; Eckenweber, Florian; Franzmeier, Nicolai; Ewers, Michael; Zott, Benedikt; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Tahirovic, Sabina; Willem, Michael; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2021):
Microglial activation in the right amygdala-entorhinal-hippocampal complex is associated with preserved spatial learning in mice.
In: Neuroimage, Bd. 230, 117707
Biechele, Gloria; Blume, Tanja; Deussing, Maximilian; Zott, Benedikt; Shi, Yuan; Xiang, Xianyuan; Franzmeier, Nicolai; Kleinberger, Gernot; Peters, Finn; Ochs, Katharina; Focke, Carola; Sacher, Christian; Wind, Karin; Schmidt, Claudio; Lindner, Simon; Gildehaus, Franz-Josef; Eckenweber, Florian; Beyer, Leonie; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Baumann, Karlheinz; Dorostkar, Mario M.; Rominger, Axel; Cumming, Paul; Willem, Michael; Adelsberger, Helmuth; Herms, Jochen und Brendel, Matthias
(2021):
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
In: Theranostics, Bd. 11, Nr. 18: S. 8964-8976
Sacher, Christian; Blume, Tanja; Beyer, Leonie; Biechele, Gloria; Sauerbeck, Julia; Eckenweber, Florian; Deussing, Maximilian; Focke, Carola; Parhizkar, Samira; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Tahirovic, Sabina; Kleinberger, Gernot; Willem, Michael; Haass, Christian; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2020):
Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models.
In: Journal of Nuclear Medicine, Bd. 61, Nr. 12
Biechele, Gloria; Franzmeier, Nicolai; Blume, Tanja; Ewers, Michael; Luque, Jose Medina; Eckenweber, Florian; Sacher, Christian; Beyer, Leonie; Ruch-Rubinstein, Francois; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Cumming, Paul; Bartenstein, Peter; Rominger, Axel; Höglinger, Günter U.; Herms, Jochen und Brendel, Matthias
(2020):
Glial activation is moderated by sex in response to amyloidosis but not to tau pathology in mouse models of neurodegenerative diseases.
In: Journal of Neuroinflammation, Bd. 17, Nr. 1, 374
Ewers, Michael; Biechele, Gloria; Suárez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627 und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
[PDF, 1MB]
Eckenweber, Florian; Medina-Luque, Jose; Blume, Tanja; Sacher, Christian; Biechele, Gloria; Wind, Karin; Deussing, Maximilian; Briel, Nils; Lindner, Simon; Boening, Guido; Ungern-Sternberg, Barbara von; Unterrainer, Marcus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Höglinger, Günter U.; Herms, Jochen und Brendel, Matthias
(2020):
Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning.
In: Journal of Neuroinflammation, Bd. 17, Nr. 1, 208
ORCID: https://orcid.org/0000-0003-0953-7624; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Höglinger, Günter U.; Herms, Jochen und Brendel, Matthias
(2020):
Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning.
In: Journal of Neuroinflammation, Bd. 17, Nr. 1, 208
Palleis, Carla; Sauerbeck, Julia; Beyer, Leonie; Harris, Stefanie; Schmitt, Julia; Morenas-Rodriguez, Estrella; Finze, Anika; Nitschmann, Alexander; Ruch-Rubinstein, Francois; Eckenweber, Florian; Biechele, Gloria; Blume, Tanja; Shi, Yuan; Weidinger, Endy; Prix, Catharina; Bötzel, Kai; Danek, Adrian; Rauchmann, Boris-Stephan; Stoecklein, Sophia; Lindner, Simon; Unterrainer, Marcus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Wetzel, Christian; Rupprecht, Rainer; Rominger, Axel; Bartenstein, Peter; Herms, Jochen; Perneczky, Robert; Haass, Christian; Levin, Johannes; Höglinger, Günter U. und Brendel, Matthias
(2020):
In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies.
In: Movement Disorders, Bd. 36, Nr. 4: S. 883-894
ORCID: https://orcid.org/0000-0003-0953-7624; Wetzel, Christian; Rupprecht, Rainer; Rominger, Axel; Bartenstein, Peter; Herms, Jochen; Perneczky, Robert; Haass, Christian; Levin, Johannes; Höglinger, Günter U. und Brendel, Matthias
(2020):
In Vivo Assessment of Neuroinflammation in 4-Repeat Tauopathies.
In: Movement Disorders, Bd. 36, Nr. 4: S. 883-894
Ewers, Michael; Biechele, Gloria; Suarez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO Molecular Medicine, Bd. 12, Nr. 9, e12308
Focke, Carola; Blume, Tanja; Zott, Benedikt; Shi, Yuan; Deussing, Maximilian; Peters, Finn; Schmidt, Claudio; Kleinberger, Gernot; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Ozmen, Laurence; Baumann, Karlheinz; Dorostkar, Mario M.; Haass, Christian; Adelsberger, Helmuth; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2019):
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.
In: Journal of Nuclear Medicine, Bd. 60, Nr. 4: S. 548-554
Brendel, Matthias; Deussing, Maximilian; Blume, Tanja; Kaiser, Lena; Probst, Federico; Overhoff, Felix; Peters, Finn; Ungern-Sternberg, Barbara von; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Yakushev, Igor; Cumming, Paul; Boening, Guido; Ziegler, Sibylle; Herms, Jochen; Giese, Armin und Rominger, Axel
(2019):
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau.
In: Alzheimers Research & Therapy, Bd. 11, 67
Sacher, Christian; Blume, Tanja; Beyer, Leonie; Peters, Finn; Eckenweber, Florian; Sgobio, Carmelo; Deussing, Maximilian; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Unterrainer, Marcus; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Brzak, Irena; Neumann, Ulf; Saito, Takashi; Saido, Takaomi C.; Bartenstein, Peter; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2019):
Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-beta Mouse Model.
In: Journal of Nuclear Medicine, Bd. 60, Nr. 12: S. 1787-1793
ORCID: https://orcid.org/0000-0003-0953-7624; Unterrainer, Marcus; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Brzak, Irena; Neumann, Ulf; Saito, Takashi; Saido, Takaomi C.; Bartenstein, Peter; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2019):
Longitudinal PET Monitoring of Amyloidosis and Microglial Activation in a Second-Generation Amyloid-beta Mouse Model.
In: Journal of Nuclear Medicine, Bd. 60, Nr. 12: S. 1787-1793
Blume, Tanja; Focke, Carola; Peters, Finn; Deussing, Maximilian; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Ozmen, Laurence; Baumann, Karlheinz; Bartenstein, Peter; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2018):
Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo PET-study.
In: Journal of Neuroinflammation
15:307
[PDF, 5MB]
ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Ozmen, Laurence; Baumann, Karlheinz; Bartenstein, Peter; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2018):
Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo PET-study.
In: Journal of Neuroinflammation
15:307
[PDF, 5MB]
Blume, Tanja; Filser, Severin; Jaworska, Anna; Blain, Jean-Francois; König, Gerhard; Moschke, Katrin; Lichtenthaler, Stefan F. und Herms, Jochen
(2018):
BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines.
In: Frontiers in Aging Neuroscience, Bd. 10, 229
[PDF, 1MB]
Peters, Finn; Salihoglu, Hazal; Rodrigues, Eva; Herzog, Etienne; Blume, Tanja; Filser, Severin; Dorostkar, Mario; Shimshek, Derya R.; Brose, Nils; Neumann, Ulf und Herms, Jochen
(2018):
BACE1 inhibition more effectively suppresses initiation than progression of beta-amyloid pathology.
In: Acta Neuropathologica, Bd. 135, Nr. 5: S. 695-710
Brendel, Matthias; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Probst, Federico; Gildehaus, Franz-Josef; Bartenstein, Peter; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Bohrmann, Bernd; Herms, Jochen; Willem, Michael und Rominger, Axel
(2018):
Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional A beta deposition rate and plaque burden at treatment initiation.
In: Theranostics, Bd. 8, Nr. 18: S. 4957-4968
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-4869-1627; Bohrmann, Bernd; Herms, Jochen; Willem, Michael und Rominger, Axel
(2018):
Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional A beta deposition rate and plaque burden at treatment initiation.
In: Theranostics, Bd. 8, Nr. 18: S. 4957-4968
[PDF, 3MB]
Deussing, Maximilian; Blume, Tanja; Vomacka, Lena; Mahler, Christoph; Focke, Carola; Todica, Andrei; Unterrainer, Marcus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2018):
Data on specificity of [F-18]GE180 uptake for TSPO expression in rodent brain and myocardium.
In: Data in Brief, Bd. 19: S. 331-336
[PDF, 1MB]
ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2018):
Data on specificity of [F-18]GE180 uptake for TSPO expression in rodent brain and myocardium.
In: Data in Brief, Bd. 19: S. 331-336
[PDF, 1MB]
Deussing, Maximilian; Blume, Tanja; Vomacka, Lena; Mahler, Christoph; Focke, Carola; Todica, Andrei; Unterrainer, Marcus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2018):
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [F-18]GE180 PET quantification.
In: Neuroimage, Bd. 165: S. 83-91
ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2018):
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [F-18]GE180 PET quantification.
In: Neuroimage, Bd. 165: S. 83-91
Brendel, Matthias; Yousefi, Behrooz H.; Blume, Tanja; Herz, Michael; Focke, Carola; Deussing, Maximilian; Peters, Finn; Lindner, Simon; Ungern-Sternberg, Barbara von; Drzezga, Alexander; Bartenstein, Peter; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Okamura, Nobuyuki; Herms, Jochen; Yakushev, Igor und Rominger, Axel
(2018):
Comparison of F-18-T807 and F-18-THK5117 PET in a Mouse Mode of Tau Pathology.
In: Frontiers in Aging Neuroscience, Bd. 10, 174
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627; Okamura, Nobuyuki; Herms, Jochen; Yakushev, Igor und Rominger, Axel
(2018):
Comparison of F-18-T807 and F-18-THK5117 PET in a Mouse Mode of Tau Pathology.
In: Frontiers in Aging Neuroscience, Bd. 10, 174
[PDF, 1MB]
Brendel, Matthias; Kleinberger, Gernot; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Albert, Nathalie L.; Carlsen, Janette; Lindner, Simon; Gildehaus, Franz Josef; Ozmen, Laurence; Suarez-Calvet, Marc; Bartenstein, Peter; Baumann, Karlheinz; Ewers, Michael; Herms, Jochen; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel
(Januar 2017):
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
In: Frontiers in aging neuroscience, Bd. 9, 8
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel
(Januar 2017):
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
In: Frontiers in aging neuroscience, Bd. 9, 8
[PDF, 2MB]
Brendel, Matthias; Focke, Carola; Blume, Tanja; Peters, Finn; Deussing, Maximilian; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Kleinberger, Gernot; Herms, Jochen und Rominger, Axel
(2017):
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
In: Journal of Nuclear Medicine, Bd. 58, Nr. 12: S. 1984-1990
ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Kleinberger, Gernot; Herms, Jochen und Rominger, Axel
(2017):
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
In: Journal of Nuclear Medicine, Bd. 58, Nr. 12: S. 1984-1990