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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 10
2021
Rieunier, Guillaume; Wu, Xiaoning; Harris, Letitia E.; Mills, Jack V.; Nandakumar, Ashwin; Colling, Laura; Seraia, Elena; Hatch, Stephanie B.; Ebner, Daniel V.; Folkes, Lisa K.; Weyer-Czernilofsky, Ulrike; Bogenrieder, Thomas; Ryan, Anderson J. und Macaulay, Valentine M.
(2021):
Targeting IGF Perturbs Global Replication through Ribonucleotide Reductase Dysfunction.
In: Cancer Research, Bd. 81, Nr. 8: S. 2128-2141
Wu, Xiaoning; Seraia, Elena; Hatch, Stephanie B.; Wan, Xiao; Ebner, Daniel V.; Aroldi, Francesca; Jiang, Yanyan; Ryan, Anderson J.; Bogenrieder, Thomas; Weyer-Czernilofsky, Ulrike; Rieunier, Guillaume und Macaulay, Valentine M.
(2021):
CHK1 inhibition exacerbates replication stress induced by IGF blockade.
In: Oncogene, Bd. 41, Nr. 4: S. 476-488
2020
de Bono, Johann; Lin, Chia-Chi; Chen, Li-Tzong; Corral, Jesus; Michalarea, Vasiliki; Rihawi, Karim; Ong, Michael; Lee, Jih-Hsiang; Hsu, Chih-Hung; Yang, James Chih-Hsin; Shiah, Her-Shyong; Yen, Chia-Jui; Anthoney, Alan; Jove, Maria; Buschke, Susanne; Fuertig, Rene; Schmid, Ulrike; Goeldner, Rainer-Georg; Strelkowa, Natalja; Huang, Dennis Chin-Lun; Bogenrieder, Thomas; Twelves, Chris und Cheng, Ann-Lii
(2020):
Two first-in-human studies of xentuzumab, a humanised insulin-like growth factor (IGF)-neutralising antibody, in patients with advanced solid tumours.
In: British Journal of Cancer, Bd. 122, Nr. 9: S. 1324-1332
Weyer-Czernilofsky, Ulrike; Hofmann, Marco H.; Friedbichler, Katrin; Baumgartinger, Rosa; Adam, Paul J.; Solca, Flavio; Kraut, Norbert; Nguyen, Holly M.; Corey, Eva; Liu, Gang; Sprenger, Cynthia C.; Plymate, Stephen R. und Bogenrieder, Thomas
(2020):
Antitumor Activity of the IGF-1/IGF-2-Neutralizing Antibody Xentuzumab (BI 836845) in Combination with Enzalutamide in Prostate Cancer Models.
In: Molecular Cancer Therapeutics, Bd. 19, Nr. 4: S. 1059-1069
2019
Rieunier, Guillaume; Wu, Xiaoning; Macaulay, Valentine M.; Lee, Adrian V.; Weyer-Czernilofsky, Ulrike und Bogenrieder, Thomas
(2019):
Bad to the Bone: The Role of the Insulin-Like Growth Factor Axis in Osseous Metastasis.
In: Clinical Cancer Research, Bd. 25, Nr. 12: S. 3479-3485
2018
Ireland, Lucy; Santos, Almudena; Campbell, Fiona; Figueiredo, Carlos; Hammond, Dean; Ellies, Lesley G.; Weyer-Czernilofsky, Ulrike; Bogenrieder, Thomas; Schmid, Michael und Mielgo, Ainhoa
(2018):
Blockade of insulin-like growth factors increases efficacy of paclitaxel in metastatic breast cancer.
In: Oncogene, Bd. 37, Nr. 15: S. 2022-2036
Aleksic, Tamara; Gray, Nicki; Wu, Xiaoning; Rieunier, Guillaume; Osher, Eliot; Mills, Jack; Verrill, Clare; Bryant, Richard J.; Han, Cheng; Hutchinson, Kathryn; Lambert, Adam G.; Kumar, Rajeev; Hamdy, Freddie C.; Weyer-Czernilofsky, Ulrike; Sanderson, Michael P.; Bogenrieder, Thomas; Taylor, Stephen und Macaulay, Valentine M.
(2018):
Nuclear IGF1R Interacts with Regulatory Regions of Chromatin to Promote RNA Polymerase II Recruitment and Gene Expression Associated with Advanced Tumor Stage.
In: Cancer Research, Bd. 78, Nr. 13: S. 3497-3509
Jeong, Inhye; Kang, Sun Kyoung; Kwon, Woo Sun; Kim, Hyun Jeong; Kim, Kyoo Hyun; Kim, Hyun Myong; Lee, Andre; Lee, Suk Kyeong; Bogenrieder, Thomas; Chung, Hyun Cheol und Rha, Sun Young
(2018):
Regulation of proliferation and invasion by the IGF signalling pathway in Epstein-Barr virus-positive gastric cancer.
In: Journal of Cellular and Molecular Medicine, Bd. 22, Nr. 12: S. 5899-5908
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2017
Simpson, Aaron; Petnga, Wilfride; Macaulay, Valentine M.; Weyer-Czernilofsky, Ulrike und Bogenrieder, Thomas
(2017):
Insulin-Like Growth Factor (IGF) Pathway Targeting in Cancer: Role of the IGF Axis and Opportunities for Future Combination Studies.
In: Targeted Oncology, Bd. 12, Nr. 5: S. 571-597
2016
Ireland, Lucy; Santos, Almudena; Ahmed, Muhammad S.; Rainer, Carolyn; Nielsen, Sebastian R.; Quaranta, Valeria; Weyer-Czernilofsky, Ulrike; Engle, Danielle D.; Perez-Mancera, Pedro A.; Coupland, Sarah E.; Taktak, Azzam; Bogenrieder, Thomas; Tuveson, David A.; Campbell, Fiona; Schmid, Michael C. und Mielgo, Ainhoa
(2016):
Chemoresistance in Pancreatic Cancer Is Driven by Stroma-Derived Insulin-Like Growth Factors.
In: Cancer Research, Bd. 76, Nr. 23: S. 6851-6863