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Anzahl der Publikationen: 15
Zeitschriftenartikel
Njavro, Jasenka Rudan; Vukicevic, Marija; Fiorini, Emma; Dinkel, Lina; Mueller, Stephan A.; Berghofer, Anna; Bordier, Chiara; Kozlov, Stanislav; Halle, Annett; Buschmann, Katrin; Capell, Anja; Giudici, Camilla; Willem, Michael; Feederle, Regina; Lichtenthaler, Stefan F.; Babolin, Chiara; Montanari, Paolo; Pfeifer, Andrea; Kosco-Vilbois, Marie und Tahirovic, Sabina
(2023):
Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.
In: Cells, Bd. 12, Nr. 1, 79
[PDF, 17MB]
Gnoerich, Johannes; Reifschneider, Anika; Wind, Karin; Zatcepin, Artem; Kunte, Sebastian T.; Beumers, Philipp; Bartos, Laura M.; Wiedemann, Thomas; Grosch, Maximilian; Xiang, Xianyuan; Fard, Maryam K.; Ruch, Francois; Werner, Georg; Koehler, Mara; Slemann, Luna; Hummel, Selina; Briel, Nils; Blume, Tanja; Shi, Yuan; Biechele, Gloria; Beyer, Leonie; Eckenweber, Florian; Scheifele, Maximilian; Bartenstein, Peter; Albert, Nathalie L.; Herms, Jochen; Tahirovic, Sabina; Haass, Christian; Capell, Anja; Ziegler, Sibylle und Brendel, Matthias
(2023):
Depletion and activation of microglia impact metabolic connectivity of the mouse brain.
In: Journal of Neuroinflammation, Bd. 20, Nr. 1, 47
[PDF, 9MB]
van Lengerich, Bettina; Zhan, Lihong; Xia, Dan; Chan, Darren; Joy, David; Park, Joshua I.; Tatarakis, David; Calvert, Meredith; Hummel, Selina; Lianoglou, Steve; Pizzo, Michelle E.; Prorok, Rachel; Thomsen, Elliot; Bartos, Laura M.; Beumers, Philipp; Capell, Anja; Davis, Sonnet S.; de Weerd, Lis; Dugas, Jason C.; Duque, Joseph; Earr, Timothy; Gadkar, Kapil; Giese, Tina; Gill, Audrey; Gnoerich, Johannes; Ha, Connie; Kannuswamy, Malavika; Kim, Do Jin; Kunte, Sebastian T.; Kunze, Lea H.; Lac, Diana; Lechtenberg, Kendra; Leung, Amy Wing-Sze; Liang, Chun-Chi; Lopez, Isabel; McQuade, Paul; Modi, Anuja; Torres, Vanessa O.; Nguyen, Hoang N.; Pesaemaa, Ida; Propson, Nicholas; Reich, Marvin; Robles-Colmenares, Yaneth; Schlepckow, Kai; Slemann, Luna; Solanoy, Hilda; Suh, Jung H.; Thorne, Robert G.; Vieira, Chandler; Wind-Mark, Karin; Xiong, Ken; Zuchero, Y. Joy Yu; Diaz, Dolo; Dennis, Mark S.; Huang, Fen; Scearce-Levie, Kimberly; Watts, Ryan J.; Haass, Christian; Lewcock, Joseph W.; Di Paolo, Gilbert; Brendel, Matthias; Sanchez, Pascal E. und Monroe, Kathryn M.
(2023):
A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.
In: Nature Neuroscience, Bd. 26, Nr. 3:
416-+
[PDF, 13MB]
Reifschneider, Anika; Robinson, Sophie; Lengerich, Bettina van; Gnörich, Johannes; Logan, Todd; Heindl, Steffanie; Vogt, Miriam A.; Weidinger, Endy; Riedl, Lina; Wind, Karin; Zatcepin, Artem; Pesaemaa, Ida; Haberl, Sophie; Nuscher, Brigitte; Kleinberger, Gernot; Klimmt, Julien; Götzl, Julia K.; Liesz, Arthur; Bürger, Katharina; Brendel, Matthias; Levin, Johannes; Diehl-Schmid, Janine; Suh, Jung; Di Paolo, Gilbert; Lewcock, Joseph W.; Monroe, Kathryn M.; Paquet, Dominik; Capell, Anja und Haass, Christian
(2022):
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.
In: EMBO Journal, Bd. 41, Nr. 4, e109108
[PDF, 3MB]
Lüningschöor, Patrick; Wemer, Georg; Stroobants, Stijn; Kakuta, Soichiro; Dombert, Benjamin; Sinske, Daniela; Wanner, Renate; Luellmann-Rauch, Renate; Wefers, Benedikt; Wurst, Wolfgang; D'Hooge, Rudi; Uchiyama, Yasuo; Sendtner, Michael; Haass, Christian; Saftig, Paul; Knöll, Bernd; Capell, Anja und Damme, Markus
(2020):
The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.
In: Cell Reports, Bd. 30, Nr. 10: S. 3506-3519
[PDF, 7MB]
Werner, Georg; Damme, Markus; Schludi, Martin; Gnoerich, Johannes; Wind, Karin; Fellerer, Katrin; Wefers, Benedikt; Wurst, Wolfgang; Edbauer, Dieter; Brendel, Matthias; Haass, Christian und Capell, Anja
(2020):
Loss ofTMEM106B potentiates lysosomal andFTLD-like pathology in progranulin-deficient mice.
In: EMBO Reports, Bd. 21, Nr. 10, e50241
[PDF, 4MB]
Götzl, Julia K.; Brendel, Matthias; Werner, Georg; Parhizkar, Samira; Monasor, Laura Sebastian; Kleinberger, Gernot; Colombo, Alessio‐Vittorio; Deussing, Maximilian; Wagner, Matias; Winkelmann, Juliane; Diehl‐Schmid, Janine; Levin, Johannes; Fellerer, Katrin; Reifschneider, Anika; Bultmann, Sebastian; Bartenstein, Peter; Rominger, Axel; Tahirovic, Sabina; Smith, Scott T.; Madore, Charlotte; Butovsky, Oleg; Capell, Anja und Haass, Christian
(2019):
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
In: Embo Molecular Medicine, Bd. 11, Nr. 6
[PDF, 1MB]
Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Schlepckow, Kai; Caballero, Miguel Angel Araque; Franzmeier, Nicolai; Capell, Anja; Fellerer, Katrin; Nuscher, Brigitte; Eren, Erden; Levin, Johannes; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian
(2019):
Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology.
In: Molecular Neurodegeneration, Bd. 14, 1
[PDF, 1MB]
Suarez-Calvet, Marc; Capell, Anja; Caballero, Miguel Angel Araque; Morenas-Rodriguez, Estrella; Fellerer, Katrin; Franzmeier, Nicolai; Kleinberger, Gernot; Eren, Erden; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Paumier, Katrina; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Jucker, Mathias; Masters, Colin L.; Rossor, Martin N.; Ringman, John M.; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
Blauwendraat, Cornelis; Wilke, Carlo; Simon-Sanchez, Javier; Jansen, Iris E.; Reifschneider, Anika; Capell, Anja; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Castillo-Lizardo, Melissa; Biskup, Saskia; Maetzler, Walter; Rizzu, Patrizia; Heutink, Peter und Synofzik, Matthis
(2018):
The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects.
In: Genetics in Medicine, Bd. 20, Nr. 2: S. 240-249
ORCID: https://orcid.org/0000-0002-4869-1627; Castillo-Lizardo, Melissa; Biskup, Saskia; Maetzler, Walter; Rizzu, Patrizia; Heutink, Peter und Synofzik, Matthis
(2018):
The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects.
In: Genetics in Medicine, Bd. 20, Nr. 2: S. 240-249
Götzl, Julia K.; Colombo, Alessio-Vittorio; Fellerer, Katrin; Reifschneider, Anika; Werner, Georg; Tahirovic, Sabina; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja
(2018):
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
In: Molecular Neurodegeneration
13:48
[PDF, 4MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja
(2018):
Early lysosomal maturation deficits in microglia triggers enhanced lysosomal activity in other brain cells of progranulin knockout mice.
In: Molecular Neurodegeneration
13:48
[PDF, 4MB]
Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
Xiang, Xianyuan; Werner, Georg; Bohrmann, Bernd; Liesz, Arthur; Mazaheri, Fargol; Capell, Anja; Feederle, Regina; Knuesel, Irene; Kleinberger, Gernot und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004
[PDF, 1MB]
Götzl, Julia K.; Lang, Christina M.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja
(2016):
Impaired protein degradation in FTLD and related disorders.
In: Ageing Research Reviews, Bd. 32: S. 122-139
ORCID: https://orcid.org/0000-0002-4869-1627 und Capell, Anja
(2016):
Impaired protein degradation in FTLD and related disorders.
In: Ageing Research Reviews, Bd. 32: S. 122-139
Kleinberger, Gernot; Capell, Anja; Brouwers, Nathalie; Fellerer, Katrin; Sleegers, Kristel; Cruts, Marc; Broeckhoven, Christine van und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin.
In: Neurobiology of Aging, Bd. 39, 220.e17
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin.
In: Neurobiology of Aging, Bd. 39, 220.e17