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Anzahl der Publikationen: 18
Zeitschriftenartikel
Orth, Martin F.; Surdez, Didier; Faehling, Tobias; Ehlers, Anna C.; Marchetto, Aruna; Grossetete, Sandrine; Volckmann, Richard; Zwijnenburg, Danny A.; Gerke, Julia S.; Zaidi, Sakina; Alonso, Javier; Sastre, Ana; Baulande, Sylvain; Sill, Martin; Cidre-Aranaz, Florencia; Ohmura, Shunya; Kirchner, Thomas; Hauck, Stefanie M.; Reischl, Eva; Gymrek, Melissa; Pfister, Stefan M.; Strauch, Konstantin; Koster, Jan; Delattre, Olivier und Grunewald, Thomas G. . P.
(2022):
Systematic multi-omics cell line profiling uncovers principles of Ewing sarcoma fusion oncogene-mediated gene regulation.
In: Cell Reports, Bd. 41, Nr. 10, 111761
Hoelting, Tilman L. B.; Cidre-Aranaz, Florencia; Matzek, Dana; Popper, Bastian; Jacobi, Severin J.; Funk, Cornelius M.; Geyer, Florian H.; Li, Jing; Piseddu, Ignazio; Cadilha, Bruno L.; Ledderose, Stephan; Zwilling, Jennifer; Ohmura, Shunya; Anz, David; Kuenkele, Annette; Klauschen, Frederick; Gruenewald, Thomas G. P. und Knott, Maximilian M. L.
(2022):
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma.
In: Molecular Cancer, Bd. 21, Nr. 1, 199
Deng, Qu; Natesan, Ramakrishnan; Cidre-Aranaz, Florencia; Arif, Shehbeel; Liu, Ying; Rasool, Reyaz ur; Wang, Pei; Mitchell-Velasquez, Erick; Das, Chandan Kanta; Vinca, Endrit; Cramer, Zvi; Grohar, Patrick J.; Chou, Margaret; Kumar-Sinha, Chandan; Weber, Kristy; Eisinger-Mathason, T. S. Karin; Grillet, Nicolas; Gruenewald, Thomas und Asangani, Irfan A.
(2022):
Oncofusion-driven de novo enhancer assembly promotes malignancy in Ewing sarcoma via aberrant expression of the stereociliary protein LOXHD1.
In: Cell Reports, Bd. 39, Nr. 11, 110971
Cidre-Aranaz, Florencia; Li, Jing; Hoelting, Tilman L. B.; Orth, Martin F.; Imle, Roland; Kutschmann, Stefanie; Ammirati, Giuli; Ceranski, Katharina; Carreno-Gonzalez, Martha Julia; Kasan, Merve; Marchetto, Aruna; Funk, Cornelius M.; Bestvater, Felix; Bersini, Simone; Arrigoni, Chiara; Moretti, Matteo; Thiel, Uwe; Baumhoer, Daniel; Sahm, Felix; Pfister, Stefan M.; Hartmann, Wolfgang; Dirksen, Uta; Romero-Perez, Laura; Banito, Ana; Ohmura, Shunya; Musa, Julian; Kirchner, Thomas; Knott, Maximilian M. L. und Grunewald, Thomas G. P.
(2022):
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma.
In: Molecular Cancer, Bd. 21, Nr. 1, 1
Li, Jing; Ohmura, Shunya; Marchetto, Aruna; Orth, Martin F.; Imle, Roland; Dallmayer, Marlene; Musa, Julian; Knott, Maximilian M. L.; Holting, Tilman L. B.; Stein, Stefanie; Funk, Cornelius M.; Sastre, Ana; Alonso, Javier; Bestvater, Felix; Kasan, Merve; Romero-Perez, Laura; Hartmann, Wolfgang; Ranft, Andreas; Banito, Ana; Dirksen, Uta; Kirchner, Thomas; Cidre-Aranaz, Florencia und Gruenewald, Thomas G. P.
(2021):
Therapeutic targeting of the PLK1-PRC1-axis triggers cell death in genomically silent childhood cancer.
In: Nature Communications, Bd. 12, Nr. 1, 5356
Marchetto, Aruna; Ohmura, Shunya; Orth, Martin F.; Knott, Maximilian M. L.; Colombo, Maria V.; Arrigoni, Chiara; Bardinet, Victor; Saucier, David; Wehweck, Fabienne S.; Li, Jing; Stein, Stefanie; Gerke, Julia S.; Baldauf, Michaela C.; Musa, Julian; Dallmayer, Marlene; Romero-Perez, Laura; Hoelting, Tilman L. B.; Amatruda, James F.; Cossarizza, Andrea; Henssen, Anton G.; Kirchner, Thomas; Moretti, Matteo; Cidre-Aranaz, Florencia; Sannino, Giuseppina und Grünewald, Thomas G. P.
(2020):
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
In: Nature Communications, Bd. 11, Nr. 1, 2423
[PDF, 2MB]
Grunewald, Thomas G. P.; Alonso, Marta; Avnet, Sofia; Banito, Ana; Burdach, Stefan; Cidre-Aranaz, Florencia; Di Pompo, Gemma; Distel, Martin; Dorado-Garcia, Heathcliff; Garcia-Castro, Javier; Gonzalez-Gonzalez, Laura; Grigoriadis, Agamemnon E.; Kasan, Merve; Koelsche, Christian; Krumbholz, Manuela; Lecanda, Fernando; Lemma, Silvia; Longo, Dario L.; Madrigal-Esquivel, Claudia; Morales-Molina, Alvaro; Musa, Julian; Ohmura, Shunya; Ory, Benjamin; Pereira-Silva, Miguel; Perut, Francesca; Rodriguez, Rene; Seeling, Carolin; Al Shaaili, Nada; Shaabani, Shabnam; Shiavone, Kristina; Sinha, Snehadri; Tomazou, Eleni M.; Trautmann, Marcel; Vela, Maria; Versleijen-Jonkers, Yvonne M. H.; Visgauss, Julia; Zalacain, Marta; Schober, Sebastian J.; Lissat, Andrej; English, William R.; Baldini, Nicola und Heymann, Dominique
(2020):
Sarcoma treatment in the era of molecular medicine.
In: EMBO Molecular Medicine, Bd. 12, Nr. 11, e11131
Orth, Martin F.; Hoelting, Tilman L. B.; Dallmayer, Marlene; Wehweck, Fabienne S.; Paul, Tanja; Musa, Julian; Baldauf, Michaela C.; Surdez, Didier; Delattre, Olivier; Knott, Maximilian M. L.; Romero-Perez, Laura; Kasan, Merve; Cidre-Aranaz, Florencia; Gerke, Julia S.; Ohmura, Shunya; Li, Jing; Marchetto, Aruna; Henssen, Anton G.; Oezen, Oezlem; Sugita, Shintaro; Hasegawa, Tadashi; Kanaseki, Takayuki; Bertram, Stefanie; Dirksen, Uta; Hartmann, Wolfgang; Kirchner, Thomas und Grünewald, Thomas G. P.
(2020):
High Specificity of BCL11B and GLG1 for EWSR1-FLI1 and EWSR1-ERG Positive Ewing Sarcoma.
In: Cancers, Bd. 12, Nr. 3, 644
Orth, Martin F.; Buecklein, Veit Leonhard; Kampmann, Eric; Subklewe, Marion; Noessner, Elfriede; Cidre-Aranaz, Florencia; Romero-Perez, Laura; Wehweck, Fabienne Sophie; Lindner, Lars; Issels, Rolf; Kirchner, Thomas; Altendorf-Hofmann, Annelore; Grunewald, Thomas G. P. und Knösel, Thomas
(2020):
A comparative view on the expression patterns of PD-L1 and PD-1 in soft tissue sarcomas.
In: Cancer Immunology Immunotherapy, Bd. 69, Nr. 7: S. 1353-1362
Dallmayer, Marlene; Li, Jing; Ohmura, Shunya; Rubio, Rebeca Alba; Baldauf, Michaela C.; Hoelting, Tilman L. B.; Musa, Julian; Knott, Max M. L.; Stein, Stefanie; Cidre-Aranaz, Florencia; Wehweck, Fabienne S.; Romero-Perez, Laura; Gerke, Julia S.; Orth, Martin F.; Marchetto, Aruna; Kirchner, Thomas; Bach, Horacio; Sannino, Giuseppina und Grünewald, Thomas G. P.
(2019):
Targeting the CALCB/RAMP1 axis inhibits growth of Ewing sarcoma.
In: Cell Death & Disease, Bd. 10, 116
Orth, Martin F.; Gerke, Julia S.; Knoesel, Thomas; Altendorf-Hofmann, Annelore; Musa, Julian; Alba-Rubio, Rebeca; Stein, Stefanie; Hoelting, Tilman L. B.; Cidre-Aranaz, Florencia; Romero-Perez, Laura; Dallmayer, Marlene; Baldauf, Michaela C.; Marchetto, Aruna; Sannino, Giuseppina; Knott, Maximilian M. L.; Wehweck, Fabienne; Ohmura, Shunya; Li, Jing; Hakozaki, Michiyuki; Kirchner, Thomas; Dandekar, Thomas; Butt, Elke und Grünewald, Thomas G. P.
(2019):
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma.
In: International Journal of Cancer, Bd. 144, Nr. 4: S. 859-867
Sannino, Giuseppina; Marchetto, Aruna; Ranft, Andreas; Jabar, Susanne; Zacherl, Constanze; Alba-Rubio, Rebeca; Stein, Stefanie; Wehweck, Fabienne S.; Kiran, Merve M.; Hoelting, Tilman L. B.; Musa, Julian; Romero-Perez, Laura; Cidre-Aranaz, Florencia; Knott, Maximilian M. L.; Li, Jing; Jürgens, Heribert; Sastre, Ana; Alonso, Javier; Da Silveira, Willian; Hardiman, Gary; Gerke, Julia S.; Orth, Martin F.; Hartmann, Wolfgang; Kirchner, Thomas; Ohmura, Shunya; Dirksen, Uta und Grünewald, Thomas G. P.
(2019):
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients.
In: Ebiomedicine, Bd. 47: S. 156-162
Musa, Julian; Cidre-Aranaz, Florencia; Aynaud, Marie-Ming; Orth, Martin F.; Knott, Maximilian M. L.; Mirabeau, Olivier; Mazor, Gal; Varon, Mor; Hoelting, Tilman L. B.; Grossetete, Sandrine; Gartlgruber, Moritz; Surdez, Didier; Gerke, Julia S.; Ohmura, Shunya; Marchetto, Aruna; Dallmayer, Marlene; Baldauf, Michaela C.; Stein, Stefanie; Sannino, Giuseppina; Li, Jing; Romero-Perez, Laura; Westermann, Frank; Hartmann, Wolfgang; Dirksen, Uta; Gymrek, Melissa; Anderson, Nathaniel D.; Shlien, Adam; Rotblat, Barak; Kirchner, Thomas; Delattre, Olivier und Grünewald, Thomas G. P.
(2019):
Cooperation of cancer drivers with regulatory germline variants shapes clinical outcomes.
In: Nature Communications, Bd. 10, 4128
[PDF, 2MB]
Knott, Maximilian M. L.; Hölting, Tilman L. B.; Ohmura, Shunya; Kirchner, Thomas; Cidre-Aranaz, Florencia und Grünewald, Thomas G. P.
(2019):
Targeting the undruggable: exploiting neomorphic features of fusion oncoproteins in childhood sarcomas for innovative therapies.
In: Cancer metastasis reviews, Bd. 38, Nr. 4: S. 625-642
[PDF, 978kB]
Gruenewald, Thomas G. P.; Cidre-Aranaz, Florencia; Surdez, Didier; Tomazou, Eleni M.; Alava, Enrique de; Kovar, Heinrich; Sorensen, Poul H.; Delattre, Olivier und Dirksen, Uta
(2018):
Ewing sarcoma.
In: Nature Reviews Disease Primers, Bd. 4, 5
Kovar, Heinrich; Amatruda, James; Brunet, Erika; Burdach, Stefan; Cidre-Aranaz, Florencia; de Alava, Enrique; Dirksen, Uta; Ent, Wietske van der; Grohar, Patrick; Grünewald, Thomas G. P.; Helman, Lee; Houghton, Peter; Iljin, Kristiina; Korsching, Eberhard; Ladanyi, Marc; Lawlor, Elizabeth; Lessnick, Stephen; Ludwig, Joseph; Meltzer, Paul; Metzler, Markus; Mora, Jaume; Moriggl, Richard; Nakamura, Takuro; Papamarkou, Theodore; Sarikas, Branka Radic; Rédini, Francoise; Richter, Guenther H. S.; Rossig, Claudia; Schadler, Keri; Schäfer, Beat W.; Scotlandi, Katia; Sheffield, Nathan C.; Shelat, Anang; Snaar-Jagalska, Ewa; Sorensen, Poul; Stegmaier, Kimberly; Stewart, Elizabeth; Sweet-Cordero, Alejandro; Szuhai, Karoly; Tirado, Oscar M.; Tirode, Franck; Toretsky, Jeffrey; Tsafou, Kalliopi; Üren, Aykut; Zinovyev, Andrei und Delattre, Olivier
(2016):
The second European interdisciplinary Ewing sarcoma research summit - A joint effort to deconstructing the multiple layers of a complex disease.
In: Oncotarget, Bd. 7, Nr. 8: S. 8613-8624
Buchbeitrag
Knott, Maximilian M. L. und Cidre-Aranaz, Florencia
(2020):
Ewing Sarcoma-Specific (Re)expression Models.
In:
Ewing Sarcoma. Methods in Molecular Biology, Bd. 2226. S. 119-138
Hölting, Tilman L. B. und Knott, Maximilian M. L.
(2020):
Analysis of Regulatory DNA Sequences by Dual-Luciferase Reporter Assays in Ewing Sarcoma.
In: Cidre-Aranaz, Florencia und Grünewald, Thomas G. P. (Hrsg.):
Ewing Sarcoma. Methods in Molecular Biology, Bd. 2226. S. 139-149