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Anzahl der Publikationen: 44
Zeitschriftenartikel
Jansen, Ris E.; Lee, Sven J. van der; Gomez-Fonseca, Duber; Rojas, Itziar de; Dalmasso, Maria Carolina; Grenier-Boley, Benjamin; Zettergren, Anna; Mishra, Aniket; Ali, Muhammad; Andrade, Victor; Bellenguez, Celine; Kleineidam, Luca; Kucukali, Fahri; Sung, Yun Ju; Tesi, Niccolo; Vromen, Ellen M.; Wightman, Douglas P.; Alcolea, Daniel; Alegret, Montserrat; Alvarez, Ignacio; Amouyel, Philippe; Athanasiu, Lavinia; Bahrami, Shahram; Bailly, Henri; Belbin, Olivia; Bergh, Sverre; Bertram, Lars; Biessels, Geert Jan; Blennow, Kaj; Blesa, Rafael; Boada, Merce; Boland, Anne; Buerger, Katharina; Carracedo, Angel; Cervera-Carles, Laura; Chene, Genevieve; Claassen, Jürgen A. H. R.; Debette, Stephanie; Deleuze, Jean-Francois; de Deyn, Peter Paul; Diehl-Schmid, Janine; Djurovic, Srdjan; Dols-Icardo, Oriol; Dufouil, Carole; Duron, Emmanuelle; Duezel, Emrah; Fladby, Tormod; Fortea, Juan; Frölich, Lutz; Garcia-Gonzalez, Pablo; Garcia-Martinez, Maria; Giegling, Ina; Goldhardt, Oliver; Gobom, Johan; Grimmer, Timo; Haapasalo, Annakaisa; Hampel, Harald; Hanon, Olivier; Hausner, Lucrezia; Heilmann-Heimbach, Stefanie; Helisalmi, Seppo; Heneka, Michael T.; Hernandez, Isabel; Herukka, Sanna-Kaisa; Holstege, Henne; Jarholm, Jonas; Kern, Silke; Knapskog, Anne-Brita; Koivisto, Anne M.; Kornhuber, Johannes; Kuulasmaa, Teemu; Lage, Carmen; Laske, Christoph; Leinonen, Ville; Lewczuk, Piotr; Lleo, Alberto; Lopez de Munain, Adolfo; Lopez-Garcia, Sara; Maier, Wolfgang; Marquie, Marta; Mol, Merel O.; Montrreal, Laura; Moreno, Fermin; Moreno-Grau, Sonia; Nicolas, Gael; Nothen, Markus M.; Orellana, Adelina; Palhaugen, Lene; Papma, Janne M.; Pasquier, Florence; Perneczky, Robert; Peters, Oliver; Pijnenburg, Yolande A. L.; Popp, Julius; Posthuma, Danielle; Pozueta, Ana; Priller, Josef; Puerta, Raquel; Quintela, Ines; Ramakers, Inez; Rodriguez-Rodriguez, Eloy; Rujescu, Dan; Saltvedt, Ingvild; Sanchez-Juan, Pascual; Scheltens, Philip; Scherbaum, Norbert; Schmid, Matthias; Schneider, Anja; Selbaek, Geir; Selnes, Per; Shadrin, Alexey; Skoog, Ingmar; Soininen, Hilkka; Tarraga, Lluis; Teipel, Stefan; Tijms, Betty; Tsolaki, Magda; Broeckhoven, Christine van; Dongen, Jasper van; Swieten, John C. van; Vandenberghe, Rik; Vidal, Jean-Sebastien; Visser, Pieter J.; Vogelgsang, Jonathan; Waern, Margda; Wagner, Michael; Wiltfang, Jens; Wittens, Mandy M. J.; Zetterberg, Henrik; Zulaica, Miren; Duijn, Cornelia M. van; Bjerke, Maria; Engelborghs, Sebastiaan; Jessen, Frank; Teunissen, Charlotte E.; Pastor, Pau; Hiltunen, Mikko; Ingelsson, Martin; Andreassen, Ole A.; Clarimon, Jordi; Sleegers, Kristel; Ruiz, Agustin; Ramirez, Alfredo; Cruchaga, Carlos; Lambert, Jean-Charles und Flier, Wiesje van der
(2022):
Genome-wide meta-analysis for Alzheimer's disease cerebrospinal fluid biomarkers.
In: Acta Neuropathologica, Bd. 144, Nr. 5: S. 821-842
Lim, Yen Ying; Maruff, Paul; Barthelemy, Nicolas R.; Goate, Alison; Hassenstab, Jason; Sato, Chihiro; Fagan, Anne M.; Benzinger, Tammie L. S.; Xiong, Chengjie; Cruchaga, Carlos; Levin, Johannes; Farlow, Martin R.; Graff-Radford, Neill R.; Laske, Christoph; Masters, Colin L.; Salloway, Stephen; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und McDade, Eric
(2022):
Association of BDNF Val66Met With Tau Hyperphosphorylation and Cognition in Dominantly Inherited Alzheimer Disease.
In: JAMA Neurology, Bd. 79, Nr. 3: S. 261-270
Luckett, Patrick H.; Chen, Charlie; Gordon, Brian A.; Wisch, Julie; Berman, Sarah B.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Jucker, Mathias; Levin, Johannes; Masters, Colin L.; Mori, Hiroshi; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Fulham, Michael J.; Ghetti, Bernardino; Jack, Clifford R.; Voeglein, Jonathan; Klunk, William E.; Koeppe, Robert; Su, Yi; Weiner, Michael; Wang, Qing; Marcus, Daniel; Koudelis, Deborah; Joseph-Mathurin, Nelly; Cash, Lisa; Hornbeck, Russ; Xiong, Chengjie; Perrin, Richard J.; Karch, Celeste M.; Hassenstab, Jason; McDade, Eric; Morris, John C.; Benzinger, Tammie L. S.; Bateman, Randall J. und Ances, Beau M.
(2022):
Biomarker clustering in autosomal dominant Alzheimer's disease.
In: Alzheimer'S & Dementia, Bd. 19, Nr. 1: S. 274-284
Chatterjee, Pratishtha; Vermunt, Lisa; Gordon, Brian A.; Pedrini, Steve; Boonkamp, Lynn; Armstrong, Nicola J.; Xiong, Chengjie; Singh, Abhay K.; Li, Yan; Sohrabi, Hamid R.; Taddei, Kevin; Molloy, Mark; Benzinger, Tammie L. S.; Morris, John C.; Karch, Celeste; Berman, Sarah; Chhatwal, Jasmeer; Cruchaga, Carlos; Graff-Radford, Neill R.; Day, Gregory S.; Farlow, Martin; Fox, Nick; Goate, Alison; Hassenstab, Jason; Lee, Jae-Hong; Levin, Johannes; McDade, Eric; Mori, Hiroshi; Perrin, Richard; Sanchez-Valle, Raquel; Schofield, Peter R.; Levey, Allan; Jucker, Mathias; Masters, Colin L.; Fagan, Anne M.; Bateman, Randall J.; Martins, Ralph N. und Teunissen, Charlotte
(2022):
Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with A beta-PET, neurodegeneration, and cognition.
In: Alzheimer'S & Dementia, Bd. 19, Nr. 7: S. 2790-2804
Joseph-Mathurin, Nelly; Llibre-Guerra, Jorge J.; Li, Yan; McCullough, Austin A.; Hofmann, Carsten; Wojtowicz, Jakub; Park, Ethan; Wang, Guoqiao; Preboske, Gregory M.; Wang, Qing; Gordon, Brian A.; Chen, Charles D.; Flores, Shaney; Aggarwal, Neelum T.; Berman, Sarah B.; Bird, Thomas D.; Black, Sandra E.; Borowski, Bret; Brooks, William S.; Chhatwal, Jasmeer P.; Clarnette, Roger; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin; Fox, Nick C.; Gauthier, Serge; Hassenstab, Jason; Hobbs, Diana A.; Holdridge, Karen C.; Honig, Lawrence S.; Hornbeck, Russ C.; Hsiung, Ging-Yuek R.; Jack, Clifford R.; Jimenez-Velazquez, Ivonne Z.; Jucker, Mathias; Klein, Gregory; Levin, Johannes; Mancini, Michele; Masellis, Mario; McKay, Nicole S.; Mummery, Catherine J.; Ringman, John M.; Shimada, Hiroyuki; Snider, B. Joy; Suzuki, Kazushi; Wallon, David; Xiong, Chengjie; Yaari, Roy; McDade, Eric; Perrin, Richard J.; Bateman, Randall J.; Salloway, Stephen P.; Benzinger, Tammie L. S. und Clifford, David B.
(2022):
Amyloid-Related Imaging Abnormalities in the DIAN-TU-001 Trial of Gantenerumab and Solanezumab: Lessons from a Trial in Dominantly Inherited Alzheimer Disease.
In: Annals of Neurology, Bd. 92, Nr. 5: S. 729-744
Chhatwal, Jasmeer P.; Schultz, Stephanie A.; McDade, Eric; Schultz, Aaron P.; Liu, Lei; Hanseeuw, Bernard J.; Joseph-Mathurin, Nelly; Feldman, Rebecca; Fitzpatrick, Colleen; Sparks, Kathryn P.; Levin, Johannes; Berman, Sarah B.; Renton, Alan E.; Esposito, Bianca; Fernandez, Maria Vitoria; Sung, Yun Ju; Lee, Jae Hong; Klunk, William E.; Hofmann, Anna; Noble, James M.; Graff-Radford, Neill; Mori, Hiroshi; Salloway, Steven M.; Masters, Colin L.; Martins, Ralph; Karch, Celeste M.; Xiong, Chengjie; Cruchaga, Carlos; Perrin, Richard J.; Gordon, Brian A.; Benzinger, Tammie L. S.; Fox, Nick C.; Schofield, Peter R.; Fagan, Anne M.; Goate, Alison M.; Morris, John C.; Bateman, Randall J.; Johnson, Keith A. und Sperling, Reisa A.
(2022):
Variant-dependent heterogeneity in amyloid beta burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.
In: Lancet Neurology, Bd. 21, Nr. 2: S. 140-152
Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C.; Kamanu, Frederick K.; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K.; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C.; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R.; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V.; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Carcel-Marquez, Jara; Nygaard, Marianne; Leonard, Hampton L.; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J.; Lewis, Adam J.; Judy, Renae L.; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D.; Bakker, Mark K.; Bartz, Traci M.; Bennett, David A.; Bis, Joshua C.; Bordes, Constance; Borte, Sigrid; Cain, Anael; Ridker, Paul M.; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W.; Jager, Phil L. de; Cid, Rafael de; Endres, Matthias; Ferreira, Leslie E.; Geerlings, Mirjam I.; Gasca, Natalie C.; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K.; Ho, Yuk-Lam; Havulinna, Aki S.; Hopewell, Jemma C.; Hyacinth, Hyacinth I.; Inouye, Michael; Jacob, Mina A.; Jeon, Christina E.; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L.; Kitazono, Takanari; Kittner, Steven J.; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J.; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S.; Marston, Nicholas A.; Meitinger, Thomas; Mitchell, Braxton D.; Montellano, Felipe A.; Morisaki, Takayuki; Mosley, Thomas H.; Nalls, Mike A.; Nordestgaard, Borge G.; O'Donnell, Martin J.; Okada, Yukinori; Onland-Moret, N. Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M.; Rich, Stephen S.; Rosand, Jonathan; Sabatine, Marc S.; Sacco, Ralph L.; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L.; Schmidt, Carsten O.; Shimizu, Atsushi; Smith, Nicholas L.; Sloane, Kelly L.; Sutoh, Yoichi; Sun, Yan V.; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P.; Tiwari, Hemant K.; Tregouet, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjaerg-Hansen, Anne; Vugt, Marion van; Vibo, Riina; Verma, Shefali S.; Wiggins, Kerri L.; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W. F.; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon; Bis, Joshua C.; Bis, Joshua C.; Lee, Jin-Moo; Cheng, Yu-Ching; Meschia, James F.; Chen, Wei Min; Sale, Michele M.; Zonderman, Alan B.; Evans, Michele K.; Wilson, James G.; Correa, Adolfo; Traylor, Matthew; Lewis, Cathryn M.; Carty, Cara L.; Reiner, Alexander; Haessler, Jeffrey; Langefeld, Carl D.; Gottesman, Rebecca F.; Yaffe, Kristine; Liu, Yong Mei; Kooperberg, Charles; Lange, Leslie A.; Furie, Karen L.; Arnett, Donna K.; Benavente, Oscar R.; Grewal, Raji P.; Peddareddygari, Leema Reddy; Kooperberg, Charles; Kooperberg, Charles; Hveem, Kristian; Lindstrom, Sara; Wang, Lu; Smith, Erin N.; Gordon, William; Hylckama Vlieg, Astrid van; de Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Brumpton, Ben M.; Suchon, Pierre; Chen, Ming-Huei; Frazer, Kelly A.; Turman, Constance; Germain, Marine; MacDonald, James; Braekkan, Sigrid K.; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rebecca D.; Nielsen, Jonas B.; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; McCauley, Bryan M.; Taylor, Kent D.; Pankow, James S.; Reiner, Alexander P.; Gabrielsen, Maiken E.; Deleuze, Jean-Francois; O'Donnell, Chris J.; Kim, Jihye; McKnight, Barbara; Kraft, Peter; Hansen, John-Bjarne; Rosendaal, Frits R.; Heit, John A.; Tang, Weihong; Morange, Pierre-Emmanuel; Johnson, Andrew D.; Kabrhel, Christopher; Dijk, Ewoud J. van; Dijk, Ewoud J. van; Koudstaal, Peter J.; Luijckx, Gert-Jan; Nederkoorn, Paul J.; Oostenbrugge, Robert J. van; Visser, Marieke C.; Wermer, Marieke J. H.; Kappelle, L. Jaap; Esko, Tonu; Esko, Tonu; Metspalu, Andres; Magi, Reedik; Nelis, Mari; Irvin, Marguerite R.; Irvin, Marguerite R.; de Leeuw, Frank-Erik; Levi, Christopher R.; Maguire, Jane; Jimenez-Conde, Jordi; Sharma, Pankaj; Sudlow, Cathie L. M.; Rannikmae, Kristiina; Schmidt, Reinhold; Slowik, Agnieszka; Pera, Joanna; Thijs, Vincent N. S.; Lindgren, Arne G.; Ilinca, Andreea; Melander, Olle; Engstrom, Gunnar; Rexrode, Kathryn M.; Rothwell, Peter M.; Stanne, Tara M.; Johnson, Julie A.; Danesh, John; Butterworth, Adam S.; Heitsch, Laura; Boncoraglio, Giorgio B.; Kubo, Michiaki; Pezzini, Alessandro; Rolfs, Arndt; Giese, Anne-Katrin; Weir, David; Jackson, Rebecca D.; Ross, Owen A.; Lemmons, Robin; Soderholm, Martin; Cushman, Mary; Jood, Katarina; McDonough, Caitrin W.; Bell, Steven; Linkohr, Birgit; Lee, Tsong-Hai; Putaala, Jukka; Anderson, Christopher D.; Anderson, Christopher D.; Lopez, Oscar L.; Jian, Xueqiu; Schminke, Ulf; Cullell, Natalia; Delgado, Pilar; Ibanez, Laura; Krupinski, Jerzy; Lioutas, Vasileios; Matsuda, Koichi; Montaner, Joan; Muino, Elena; Roquer, Jaume; Sarnowski, Chloe; Sattar, Naveed; Sibolt, Gerli; Teumer, Alexander; Rutten-Jacobs, Loes; Kanai, Masahiro; Giese, Anne-Katrin; Gretarsdottir, Solveig; Rost, Natalia S.; Yusuf, Salim; Almgren, Peter; Ay, Hakan; Bevan, Steve; Brown, Robert D.; Carrera, Caty; Buring, Julie E.; Chen, Wei-Min; Cotlarciuc, Ioana; de Bakker, Paul I. W.; DeStefano, Anita L.; Hoed, Marcel den; Duan, Qing; Engelter, Stefan T.; Falcone, Guido J.; Gottesman, Rebecca F.; Gustafsson, Stefan; Hassan, Ahamad; Holliday, Elizabeth G.; Howard, George; Hsu, Fang-Chi; Ingelsson, Erik; Harris, Tamara B.; Kissela, Brett M.; Kleindorfer, Dawn O.; Langenberg, Claudia; Lemmens, Robin; Leys, Didier; Lin, Wei-Yu; Lorentzen, Erik; Magnusson, Patrik K.; McArdle, Patrick F.; Pulit, Sara L.; Rice, Kenneth; Sakaue, Saori; Sapkota, Bishwa R.; Tanislav, Christian; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tzourio, Christophe; Duijn, Cornelia M. van; Walters, Matthew; Wareham, Nicholas J.; Amin, Najaf; Aparicio, Hugo J.; Attia, John; Beiser, Alexa S.; Berr, Claudine; Bustamante, Mariana; Caso, Valeria; Choi, Seung Hoan; Chowhan, Ayesha; Dartigues, Jean-Francois; Delavaran, Hossein; Dorr, Marcus; Ford, Ian; Gurpreet, Wander S.; Hamsten, Anders; Hozawa, Atsushi; Ingelsson, Martin; Iwasaki, Motoki; Kaffashian, Sara; Kalra, Lalit; Kjartansson, Olafur; Kloss, Manja; Labovitz, Daniel L.; Laurie, Cathy C.; Li, Linxin; Lind, Lars; Lindgren, Cecilia M.; Makoto, Hirata; Minegishi, Naoko; Morris, Andrew P.; Müller-Nurasyid, Martina; Norrving, Bo; Ogishima, Soichi; Parati, Eugenio A.; Pedersen, Nancy L.; Perola, Markus; Jousilahti, Pekka; Pileggi, Silvana; Rabionet, Raquel; Riba-Llena, Iolanda; Ribases, Marta; Romero, Jose R.; Rudd, Anthony G.; Sarin, Antti-Pekka; Sarju, Ralhan; Satoh, Mamoru; Sawada, Norie; Sigurdsson, Asgeir; Smith, Albert; Stine, O. Colin; Stott, David J.; Strauch, Konstantin; Takai, Takako; Tanaka, Hideo; Touze, Emmanuel; Tsugane, Shoichiro; Uitterlinden, Andre G.; Valdimarsson, Einar M.; Lee, Sven J. van der; Wakai, Kenji; Williams, Stephen R.; Wolfe, Charles D. A.; Wong, Quenna; Yamaji, Taiki; Sanghera, Dharambir K.; Stefansson, Kari; Taylor, Kent D.; Martinez-Majander, Nicolas; Sobue, Kenji; Soriano-Tarraga, Carolina; Volzke, Henry; Akpa, Onoja; Akpa, Onoja; Sarfo, Fred S.; Akpalu, Albert; Obiako, Reginald; Wahab, Kolawole; Osaigbovo, Godwin; Owolabi, Lukman; Komolafe, Morenikeji; Jenkins, Carolyn; Arulogun, Oyedunni; Ogbole, Godwin; Adeoye, Abiodun M.; Akinyemi, Joshua; Agunloye, Atinuke; Fakunle, Adekunle G.; Uvere, Ezinne; Olalere, Abimbola; Adebajo, Olayinka J.; Chen, Junshi; Chen, Junshi; Clarke, Robert; Collins, Rory; Guo, Yu; Wang, Chen; Lv, Jun; Peto, Richard; Chen, Yiping; Fairhurst-Hunter, Zammy; Hill, Michael; Pozarickij, Alfred; Schmidt, Dan; Stevens, Becky; Turnbull, Iain; Yu, Canqing; Le Grand, Quentin; Le Grand, Quentin; Ferreira, Leslie E.; Nagai, Akiko; Nagai, Akiko; Murakami, Yoishinori; Geerlings, Mirjam I.; Geerlings, Mirjam I.; Gasca, Natalie C.; Gudnason, Vilmundur; Vugt, Marion van; Gottesman, Rebecca F.; Shiroma, Eric J.; Sigurdsson, Sigurdur; Ghanbari, Mohsen; Boerwinkle, Eric; Beiser, Alexa S.; Fongang, Bernard; Wang, Ruiqi; Ikram, Mohammad K.; Volker, Uwe; de Jager, Phil L.; de Jager, Phil L.; de Cid, Rafael; Nordestgaard, Borge G.; Sargurupremraj, Muralidharan; Verma, Shefali S.; de Laat, Karlijn F.; de Laat, Karlijn F.; Norden, Anouk G. W. van; de Kort, Paul L.; Vermeer, Sarah E.; Brouwers, Paul J. A. M.; Gons, Rob A. R.; Nederkoorn, Paul J.; den Heijer, Tom; Dijk, Gert W. van; Rooij, Frank G. W. van; Aamodt, Anne H.; Aamodt, Anne H.; Skogholt, Anne H.; Brumpton, Ben M.; Willer, Cristen J.; Heuch, Ingrid; Hagen, Knut; Fritsche, Lars G.; Pedersen, Linda M.; Gabrielsen, Maiken E.; Ellekjaer, Hanne; Zhou, Wei; Martinsen, Amy E.; Kristoffersen, Espen S.; Nielsen, Jonas B.; Hveem, Kristian; Thomas, Laurent F.; Kleinschnitz, Christoph; Kleinschnitz, Christoph; Frantz, Stefan; Ungethum, Kathrin; Gallego-Fabrega, Cristina; Gallego-Fabrega, Cristina; Lledos, Miquel; Llucia-Carol, Laia; Sobrino, Tomas; Campos, Francisco; Castillo, Jose; Freijo, Marimar; Arenillas, Juan Francisco; Obach, Victor; Alvarez-Sabin, Jose; Molina, Carlos A.; Ribo, Marc; Munoz-Narbona, Lucia; Lopez-Cancio, Elena; Millan, Monica; Diaz-Navarro, Rosa; Vives-Bauza, Cristofol; Serrano-Heras, Gemma; Segura, Tomas; Delgado, Pilar; Dhar, Rajat; Delgado-Mederos, Raquel; Prats-Sanchez, Luis; Camps-Renom, Pol; Blay, Natalia; Sumoy, Lauro; Marti-Fabregas, Joan; Schnohr, Peter; Schnohr, Peter; Jensen, Gorm B.; Benn, Marianne; Afzal, Shoaib; Kamstrup, Pia R.; Setten, Jessica van; Laan, Sander W. van der; Vonk, Jet M. J.; Kim, Bong-Jo; Kim, Bong-Jo; Curtze, Sami; Curtze, Sami; Tiainen, Marjaana; Kinnunen, Janne; Menon, Vilas; Menon, Vilas; Sung, Yun Ju; Yang, Chengran; Saillour-Glenisson, Florence; Gravel, Simon; Onland-Moret, N. Charlotte; Onland-Moret, N. Charlotte; Heath, Alicia K.; Millwood, Iona Y.; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J.; Jukema, J. Wouter; Rissanen, Ina L.; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M. M.; Irvin, Marguerite R.; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A.; Rundek, Tatjana; Worrall, Bradford B.; Lathrop, G. Mark; Riaz, Moeen; Simonsick, Eleanor M.; Korv, Janika; Franca, Paulo H. C.; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M.; Heuschmann, Peter Ulrich; Longstreth, W. T.; Jung, Keum Ji; Bastarache, Lisa; Pare, Guillaume; Damrauer, Scott M.; Chasman, Daniel I.; Rotter, Jerome I.; Anderson, Christopher D.; Zwart, John-Anker; Niiranen, Teemu J.; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernandez-Cadenas, Israel; Walters, Robin G.; Ruff, Christian T.; Owolabi, Mayowa O.; Huffman, Jennifer E.; Milani, Lili; Kamatani, Yoichiro; Dichgans, Martin und Debette, Stephanie
(2022):
Stroke genetics informs drug discovery and risk prediction across ancestries.
In: Nature, Bd. 611, Nr. 7934: S. 115-123
Morris, John C.; Weiner, Michael; Xiong, Chengjie; Beckett, Laurel; Coble, Dean; Saito, Naomi; Aisen, Paul S.; Allegri, Ricardo; Benzinger, Tammie L. S.; Berman, Sarah B.; Cairns, Nigel J.; Carrillo, Maria C.; Chui, Helena C.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin; Fox, Nick C.; Ghetti, Bernardino; Goate, Alison M.; Gordon, Brian A.; Graff-Radford, Neill; Day, Gregory S.; Hassenstab, Jason; Ikeuchi, Takeshi; Jack, Clifford R.; Jagust, William J.; Jucker, Mathias; Levin, Johannes; Massoumzadeh, Parinaz; Masters, Colin L.; Martins, Ralph; McDade, Eric; Mori, Hiroshi; Noble, James M.; Petersen, Ronald C.; Ringman, John M.; Salloway, Stephen; Saykin, Andrew J.; Schofield, Peter R.; Shaw, Leslie M.; Toga, Arthur W.; Trojanowski, John Q.; Voeglein, Jonathan; Weninger, Stacie; Bateman, Randall J. und Buckles, Virginia D.
(2022):
Autosomal dominant and sporadic late onset Alzheimer's disease share a common in vivo pathophysiology.
In: Brain, Bd. 145, Nr. 10: S. 3594-3607
Luo, Jingqin; Agboola, Folasade; Grant, Elizabeth; Morris, John C.; Masters, Colin L.; Albert, Marilyn S.; Johnson, Sterling C.; McDade, Eric M.; Fagan, Anne M.; Benzinger, Tammie L. S.; Hassenstab, Jason; Bateman, Randall J.; Perrin, Richard J.; Wang, Guoqiao; Li, Yan; Gordon, Brian; Cruchaga, Carlos; Day, Gregory S.; Levin, Johannes; Voeglein, Jonathan; Ikeuchi, Takeshi; Suzuki, Kazushi; Allegri, Ricardo F. und Xiong, Chengjie
(2022):
Accelerated longitudinal changes and ordering of Alzheimer disease biomarkers across the adult lifespan.
In: Brain, Bd. 145, Nr. 12: S. 4459-4473
Jaworek, Thomas; Xu, Huichun; Gaynor, Brady J.; Cole, John W.; Rannikmae, Kristiina; Stanne, Tara M.; Tomppo, Liisa; Abedi, Vida; Amouyel, Philippe; Armstrong, Nicole D.; Attia, John; Bell, Steven; Benavente, Oscar R.; Boncoraglio, Giorgio B.; Butterworth, Adam; Carcel-Marquez, Jara; Chen, Zhengming; Chong, Michael; Cruchaga, Carlos; Cushman, Mary; Danesh, John; Debette, Stephanie; Duggan, David J.; Durda, Jon Peter; Engstrom, Gunnar; Enzinger, Chris; Faul, Jessica D.; Fecteau, Natalie S.; Fernandez-Cadenas, Israel; Gieger, Christian; Giese, Anne-Katrin; Grewal, Raji P.; Grittner, Ulrike; Havulinna, Aki S.; Heitsch, Laura; Hochberg, Marc C.; Holliday, Elizabeth; Hu, Jie; Ilinca, Andreea; Irvin, Marguerite R.; Jackson, Rebecca D.; Jacob, Mina A.; Rabionet, Raquel; Jimenez-Conde, Jordi; Johnson, Julie A.; Kamatani, Yoichiro; Kardia, Sharon L. R.; Koido, Masaru; Kubo, Michiaki; Lange, Leslie; Lee, Jin-Moo; Lemmens, Robin; Levi, Christopher R.; Li, Jiang; Li, Liming; Lin, Kuang; Lopez, Haley; Luke, Sothear; Maguire, Jane; McArdle, Patrick F.; McDonough, Caitrin W.; Meschia, James F.; Metso, Tiina; Müller-Nurasyid, Martina; O'Connor, Timothy D.; O'Donnell, Martin; Peddareddygari, Leema R.; Pera, Joanna; Perry, James A.; Peters, Annette; Putaala, Jukka; Ray, Debashree; Rexrode, Kathryn; Ribases, Marta; Rosand, Jonathan; Rothwell, Peter M.; Rundek, Tatjana; Ryan, Kathleen A.; Sacco, Ralph L.; Salomaa, Veikko; Sanchez-Mora, Cristina; Schmidt, Reinhold; Sharma, Pankaj; Slowik, Agnieszka; Smith, Jennifer A.; Smith, Nicholas L.; Wassertheil-Smoller, Sylvia; Soderholm, Martin; Stine, O. Colin; Strbian, Daniel; Sudlow, Cathie L. M.; Tatlisumak, Turgut; Terao, Chikashi; Thijs, Vincent; Torres-Aguila, Nuria P.; Tregouet, David-Alexandre; Tuladhar, Anil M.; Veldink, Jan H.; Walters, Robin G.; Weir, David R.; Woo, Daniel; Worrall, Bradford B.; Hong, Charles C.; Ross, Owen A.; Zand, Ramin; Leeuw, Frank-Erik de; Lindgren, Arne G.; Pare, Guillaume; Anderson, Christopher D.; Markus, Hugh S.; Jern, Christina; Malik, Rainer; Dichgans, Martin; Mitchell, Braxton D. und Kittner, Steven J.
(2022):
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.
In: Neurology, Bd. 99, Nr. 16, E1738-E1754
Ali, Muhammad M.; Sung, Yun Ju; Wang, Fengxian; Fernandez, Maria; Morris, John M.; Fagan, Anne; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella R.; Kleinberger, Gernot J.; Haass, Christian; Ewers, Michael; Levin, Johannes; Farlow, Martin; Perrin, Richard und Cruchaga, Carlos
(2022):
Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.
In: PLOS One 17(5), e0267298
In: PLOS One 17(5), e0267298
Montal, Victor; Vilaplana, Eduard; Pegueroles, Jordi; Bejanin, Alexandre; Alcolea, Daniel; Carmona-Iragui, Maria; Clarimon, Jordi; Levin, Johannes; Cruchaga, Carlos; Graff-Radford, Neill R.; Noble, James M.; Lee, Jae-Hong; Allegri, Ricardo; Karch, Celeste M.; Laske, Christoph; Schofield, Peter R.; Salloway, Stephen; Ances, Beau; Benzinger, Tammie; McDale, Eric; Bateman, Randall; Blesa, Rafael; Sanchez-Valle, Raquel; Lleo, Alberto und Fortea, Juan
(2021):
Biphasic cortical macro- and microstructural changes in autosomal dominant Alzheimer's disease.
In: Alzheimers & Dementia, Bd. 17, Nr. 4: S. 618-628
Luckett, Patrick H.; McCullough, Austin; Gordon, Brian A.; Strain, Jeremy; Flores, Shaney; Dincer, Aylin; McCarthy, John; Kuffner, Todd; Stern, Ari; Meeker, Karin L.; Berman, Sarah B.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fagan, Anne M.; Farlow, Martin R.; Fox, Nick C.; Jucker, Mathias; Levin, Johannes; Masters, Colin L.; Mori, Hiroshi; Noble, James M.; Salloway, Stephen; Schofield, Peter R.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Fulham, Michael J.; Ghetti, Bernardino; Jack, Clifford R.; Vöglein, Jonathan; Klunk, William; Koeppe, Robert; Oh, Hwamee; Su, Yi; Weiner, Michael; Wang, Qing; Swisher, Laura; Marcus, Dan; Koudelis, Deborah; Joseph-Mathurin, Nelly; Cash, Lisa; Hornbeck, Russ; Xiong, Chengjie; Perrin, Richard J.; Karch, Celeste M.; Hassenstab, Jason; McDade, Eric; Morris, John C.; Benzinger, Tammie L. S.; Bateman, Randall J. und Ances, Beau M.
(2021):
Modeling autosomal dominant Alzheimer's disease with machine learning.
In: Alzheimers & Dementia, Bd. 17, Nr. 6: S. 1005-1016
Joseph-Mathurin, Nelly; Wang, Guoqiao; Kantarci, Kejal; Jr, Clifford R. Jack; McDade, Eric; Hassenstab, Jason; Blazey, Tyler M.; Gordon, Brian A.; Su, Yi; Chen, Gengsheng; Massoumzadeh, Parinaz; Hornbeck, Russ C.; Allegri, Ricardo F.; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Chui, Helena C.; Correia, Stephen; Cruchaga, Carlos; Farlow, Martin R.; Fox, Nick C.; Fulham, Michael; Ghetti, Bernardino; Graff-Radford, Neill R.; Johnson, Keith A.; Karch, Celeste M.; Laske, Christoph; Lee, Athene K. W.; Levin, Johannes; Masters, Colin L.; Noble, James M.; O'Connor, Antoinette; Perrin, Richard J.; Preboske, Gregory M.; Ringman, John M.; Rowe, Christopher C.; Salloway, Stephen; Saykin, Andrew J.; Schofield, Peter R.; Shimada, Hiroyuki; Shoji, Mikio; Suzuki, Kazushi; Villemagne, Victor L.; Xiong, Chengjie; Yakushev, Igor; Morris, John C.; Bateman, Randall J. und Benzinger, Tammie L. S.
(2021):
Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease.
In: Neurology, Bd. 96, Nr. 12, E1632-E1645
Ewers, Michael; Luan, Ying; Frontzkowski, Lukas; Neitzel, Julia; Rubinski, Anna; Dichgans, Martin; Hassenstab, Jason; Gordon, Brian A.; Chhatwal, Jasmeer P.; Levin, Johannes; Schofield, Peter; Benzinger, Tammie L. S.; Morris, John C.; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Allegri, Ricardo; Berman, Sarah; Chui, Helena; Cruchaga, Carlos; Farlow, Marty; Graff-Radford, Neill; Jucker, Mathias; Lee, Jae-Hong; Martins, Ralph N.; Mori, Hiroshi; Perrin, Richard; Xiong, Chengjie; Rossor, Martin; Fox, Nick C.; O'Connor, Antoinette; Salloway, Stephen; Danek, Adrian; Buerger, Katharina; Bateman, Randall J.; Habeck, Christian; Stern, Yaakov und Franzmeier, Nicolai
(2021):
Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease.
In: Brain, Bd. 144: S. 2176-2185
Castillo-Barnes, Diego; Su, Li; Ramirez, Javier; Salas-Gonzalez, Diego; Martinez-Murcia, Francisco J.; Illan, Ignacio A.; Segovia, Fermin; Ortiz, Andres; Cruchaga, Carlos; Farlow, Martin R.; Xiong, Chengjie; Graff-Radford, Neil R.; Schofield, Peter R.; Masters, Colin L.; Salloway, Stephen; Jucker, Mathias; Mori, Hiroshi; Levin, Johannes und Gorriz, Juan M.
(2020):
Autosomal dominantly inherited alzheimer disease: Analysis of genetic subgroups by machine learning.
In: Information Fusion, Bd. 58: S. 153-167
Luo, Jingqin; Agboola, Folasade; Grant, Elizabeth; Masters, Colin L.; Albert, Marilyn S.; Johnson, Sterling C.; McDade, Eric M.; Voglein, Jonathan; Fagan, Anne M.; Benzinger, Tammie; Massoumzadeh, Parinaz; Hassenstab, Jason; Bateman, Randall J.; Morris, John C.; Perrin, Richard J.; Chhatwal, Jasmeer; Jucker, Mathias; Ghetti, Bernardino; Cruchaga, Carlos; Graff-Radford, Neill R.; Schofield, Peter R.; Mori, Hiroshi und Xiong, Chengjie
(2020):
Sequence of Alzheimer disease biomarker changes in cognitively normal adults A cross-sectional study.
In: Neurology, Bd. 95, Nr. 23, E3104-E3116
Keene, Keith L.; Hyacinth, Hyacinth I.; Bis, Joshua C.; Kittner, Steven J.; Mitchell, Braxton D.; Cheng, Yu-Ching; Pare, Guillaume; Chong, Michael; O'Donnell, Martin; Meschia, James F.; Chen, Wei-Min; Sale, Michele M.; Rich, Stephen S.; Nalls, Mike A.; Zonderman, Alan B.; Evans, Michele K.; Wilson, James G.; Correa, Adolfo; Markus, Hugh S.; Traylor, Matthew; Lewis, Cathryn M.; Carty, Cara L.; Reiner, Alexander; Haessler, Jeff; Langefeld, Carl D.; Gottesman, Rebecca; Mosley, Thomas H.; Woo, Daniel; Yaffe, Kristine; Liu, YongMei; Longstreth, William T.; Psaty, Bruce M.; Kooperberg, Charles; Lange, Leslie A.; Sacco, Ralph; Rundek, Tatjana; Lee, Jin-Moo; Cruchaga, Carlos; Furie, Karen L.; Arnett, Donna K.; Benavente, Oscar R.; Grewal, Raji P.; Peddareddygari, Leema Reddy; Dichgans, Martin; Malik, Rainer; Worrall, Bradford B. und Fornage, Myriam
(2020):
Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
In: Stroke, Bd. 51, Nr. 8: S. 2454-2463
Vermunt, Lisa; Dicks, Ellen; Wang, Guoqiao; Dincer, Aylin; Flores, Shaney; Keefe, Sarah J.; Berman, Sarah B.; Cash, David M.; Chhatwal, Jasmeer P.; Cruchaga, Carlos; Fox, Nick C.; Ghetti, Bernardino; Graff-Radford, Neill R.; Hassenstab, Jason; Karch, Celeste M.; Laske, Christoph; Levin, Johannes; Masters, Colin L.; McDade, Eric; Mori, Hiroshi; Morris, John C.; Noble, James M.; Perrin, Richard J.; Schofield, Peter R.; Xiong, Chengjie; Scheltens, Philip; Visser, Pieter Jelle; Bateman, Randall J.; Benzinger, Tammie L. S.; Tijms, Betty M. und Gordon, Brian A.
(2020):
Single-subject grey matter network trajectories over the disease course of autosomal dominant Alzheimer's disease.
In: Brain Communications, Bd. 2, Nr. 2, 102
Gao, Yixin; Wang, Ting; Yu, Xinghao; Zhao, Huashuo; Zeng, Ping; Ferrari, Raffaele; Hernandez, Dena G.; Nails, Michael A.; Rohrers, Jonathan D.; Ramasamys, Adaikalavan; Kwok, John B. J.; Dobson-Stone, Carol; Brooks, William S.; Schofield, Peter R.; Halliday, Glenda M.; Hodges, John R.; Piguet, Olivier; Bartley, Lauren; Thompson, Elizabeth; Haan, Eric; Hernandez, Isabel; Ruiz, Agustin; Boada, Merce; Borronils, Barbara; Padovani, Alessandro; Cruchaga, Carlos; Cairns, Nigel J.; Benussi, Luisa; Binetti, Giuliano; Ghidoni, Roberta; Forloni, Gianluigi; Albani, Diego; Galimberti, Daniela; Fenoglio, Chiara; Serpente, Maria; Scarpini, Elio; Clarim, Jordi; Lie, Alberto; Blesa, Rafael; Waldo, Maria Landqvist; Nilsson, Karin; Nilsson, Christer; Mackenzie, Ian R. A.; Hsiung, Ging-Yuek R.; Mann, David M. A.; Grafman, Jordan; Morris, Christopher M.; Attems, Johannes; Griffiths, Timothy D.; McKeith, Ian G.; Thomas, Alan J.; Pietrini, Pietro; Huey, Edward D.; Wassermann, Eric M.; Baborie, Atik; Jaros, Evelyn; Tierney, Michael C.; Pastor, Pau; Razquin, Cristina; Ortega-Cubero, Sara; Alonso, Elena; Perneczky, Robert; Diehl-Schmid, Janine; Alexopoulos, Panagiotis; Kurz, Alexander; Rainero, Innocenzo; Rubino, Elisa; Pinessi, Lorenzo; Rogaeva, Ekaterina; St George-Hyslop, Peter; Rossi, Giacomina; Tagliavini, Fabrizio; Giacconen, Giorgio; Rowe, James B.; Schlachetzki, Johannes C. M.; Uphill, James; Collinge, John; Mead, Simon; Danek, Adrian; Deerlin, Vivienne M. van; Grossman, Murray; Trojanowski, John Q.; Zee, Julie van der; Cruts, Marc; Broeckhoven, Christine van; Cappa, Stefano F.; Leber, Isabelle; Hannequin, Didier; Golfier, Veronique; Vercelletto, Martine; Brice, Alexis; Nacmias, Benedetta; Sorbi, Sandro; Bagnoli, Silvia; Piaceri, Irene; Nielsen, Jorgen E.; Hjermind, Lena E.; Riemenschneider, Matthias; Mayhaus, Manuel; Ibach, Bernd; Gasparoni, Gilles; Pichler, Sabrina; Gu, Wei; Rossor, Martin N.; Fox, Nick C.; Warren, Jason D.; Spillantini, Maria Grazia; Morris, Huw R.; Rizzu, Patrizia; Heutink, Peter; Snowden, Julie S.; Rollinson, Sara; Richardson, Anna; Gerhard, Alexander; Bruni, Amalie C.; Maletta, Raffaele; Frangipane, Francesca; Cupidi, Chiara; Bernardi, Livia; Anfossi, Maria; Gallo, Maura; Conidi, Maria Elena; Smirne, Nicoletta; Rademakers, Rosa; Baker, Matt; Dickson, Dennis W.; Graff-Radford, Neill R.; Petersen, Ronald C.; Knopman, David; Josephs, Keith A.; Boeve, Bradley F.; Parisi, Joseph E.; Seeley, William W.; Miller, Bruce L.; Karydas, Anna M.; Rosen, Howard; Swieten, John C. van; Dopper, Elise G. P.; Seelaar, Harro; Pijnenburg, Yolande A. L.; Scheltens, Philip; Logroscino, Giancarlo; Capozzo, Rosa; Novelli, Valeria; Puca, Annibale A.; Franceschi, Massimo; Postiglione, Alfredo; Milan, Graziella; Sorrentino, Paolo; Kristiansen, Mark; Huei-Hsin, G.; Graff, Chian Caroline; Pasquier, Florence; Rollin, Adeline; Deramecourt, Vincent; Lebouvier, Thibaud; Ferrucci, Luigi; Pickering-Brown, Stuart; Singleton, Andrew B.; Hardy, John und Momeni, Parastoo
(2020):
Mendelian randomization implies no direct causal association between leukocyte telomere length and amyotrophic lateral sclerosis.
In: Scientific Reports, Bd. 10, Nr. 1, 12184
[PDF, 1MB]
Barthelemy, Nicolas R.; Li, Yan; Joseph-Mathurin, Nelly; Gordon, Brian A.; Hassenstab, Jason; Benzinger, Tammie. L. S.; Buckles, Virginia; Fagan, Anne M.; Perrin, Richard J.; Goate, Alison M.; Morris, John C.; Karch, Celeste M.; Xiong, Chengjie; Allegri, Ricardo; Mendez, Patricio Chrem; Berman, Sarah B.; Ikeuchi, Takeshi; Mori, Hiroshi; Shimada, Hiroyuki; Shoji, Mikio; Suzuki, Kazushi; Noble, James; Farlow, Martin; Chhatwal, Jasmeer; Graff-Radford, Neill R.; Salloway, Stephen; Schofield, Peter R.; Masters, Colin L.; Martins, Ralph N.; O'Connor, Antoinette; Fox, Nick C.; Levin, Johannes; Jucker, Mathias; Gabelle, Audrey; Lehmann, Sylvain; Sato, Chihiro; Bateman, Randall J.; McDade, Eric; Allegri, Ricardo; Allegri, Ricardo; Bateman, Randy; Bechara, Jacob; Benzinger, Tammie; Berman, Sarah; Bodge, Courtney; Brandon, Susan; Brooks, William; Buck, Jill; Buckles, Virginia; Chea, Sochenda; Chhatwal, Jasmeer; Mendez, Patricio; Chui, Helena; Cinco, Jake; Clifford, Jack; Cruchaga, Carlos; Donahue, Tamara; Douglas, Jane; Edigo, Noelia; Erekin-Taner, Nilufer; Fagan, Anne; Farlow, Martin; Fitzpatrick, Colleen; Flynn, Gigi; Fox, Nick; Franklin, Erin; Fujii, Hisako; Gant, Cortaiga; Gardener, Samantha; Ghetti, Bernardino; Goate, Alison; Goldman, Jill; Gordon, Brian; Graff-Radford, Neill; Gray, Julia; Groves, Alexander; Hassenstab, Jason; Hoechst-Swisher, Laura; Holtzman, David; Hornbeck, Russ; DiBari, Siri Houeland; Ikeuchi, Takeshi; Ikonomovic, Snezana; Jerome, Gina; Jucker, Mathias; Karch, Celeste; Kasuga, Kensaku; Kawarabayashi, Takeshi; Klunk, William; Koeppe, Robert; Kuder-Buletta, Elke; Laske, Christoph; Lee, Jae-Hong; Levin, Johannes; Martins, Ralph; Mason, Neal Scott; Masters, Colin; Maue-Dreyfus, Denise; McDade, Eric; Mori, Hiroshi; Morris, John; Nagamatsu, Akem; Neimeyer, Katie; Noble, James; Norton, Joanne; Perrin, Richard; Raichle, Marc; Renton, Alan; Ringman, John; Roh, Jee Hoon; Salloway, Stephen; Schofield, Peter; Shimada, Hiroyuki; Sigurdson, Wendy; Sohrabi, Hamid; Sparks, Paige; Suzuki, Kazushi; Taddei, Kevin; Wang, Peter; Xiong, Chengjie und Xu, Xiong
(2020):
A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease.
In: Nature Medicine, Bd. 26, Nr. 3: S. 398-407
Schultz, Stephanie A.; Strain, Jeremy F.; Adedokun, Adedamola; Wang, Qing; Preische, Oliver; Kuhle, Jens; Flores, Shaney; Keefe, Sarah; Dincer, Aylin; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Cash, David M.; Chhatwal, Jasmeer; Cruchaga, Carlos; Ewers, Michael; Fox, Nick N.; Ghetti, Bernardino; Goate, Alison; Graff-Radford, Neill R.; Hassenstab, Jason J.; Hornbeck, Russ; Jack, Clifford; Johnson, Keith; Joseph-Mathurin, Nelly; Karch, Celeste M.; Koeppe, Robert A.; Lee, Athene K. W.; Levin, Johannes; Masters, Colin; McDade, Eric; Perrin, Richard J.; Rowe, Christopher C.; Salloway, Stephen; Saykin, Andrew J.; Sperling, Reisa; Su, Yi; Villemagne, Victor L.; Voeglein, Jonathan; Weiner, Michael; Xiong, Chengjie; Fagan, Anne M.; Morris, John C.; Bateman, Randall J.; Benzinger, Tammie L. S.; Jucker, Mathias und Gordon, Brian A.
(2020):
Serum neurofilament light chain levels are associated with white matter integrity in autosomal dominant Alzheimer's disease.
In: Neurobiology of Disease, Bd. 142, 104960
Aschenbrenner, Andrew J.; James, Bryan D.; McDade, Eric; Wang, Guoqiao; Lim, Yen Ying; Benzinger, Tammie L. S.; Cruchaga, Carlos; Goate, Alison; Xiong, Chengjie; Perrin, Richard; Buckles, Virginia; Allegri, Ricardo; Berman, Sarah B.; Chhatwal, Jasmeer P.; Fagan, Anne; Farlow, Martin; O'Connor, Antoinette; Ghetti, Bernardino; Graff-Radford, Neill; Goldman, Jill; Graeber, Susanne; Karch, Celeste M.; Lee, Jae-Hong; Levin, Johannes; Martins, Ralph N.; Masters, Colin; Mori, Hiroshi; Noble, James; Salloway, Stephen; Schofield, Peter; Morris, John C.; Bateman, Randall J. und Hassenstab, Jason
(2020):
Awareness of genetic risk in the Dominantly Inherited Alzheimer Network (DIAN).
In: Alzheimer's and Dementia, Bd. 16, Nr. 1: S. 219-228
Ewers, Michael; Biechele, Gloria; Suarez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO Molecular Medicine, Bd. 12, Nr. 9, e12308
Ewers, Michael; Biechele, Gloria; Suárez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627 und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
[PDF, 1MB]
Ewers, Michael; Franzmeier, Nicolai; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Caballero, Miguel Angel Araque; Kleinberger, Gernot; Piccio, Laura; Cruchaga, Carlos; Deming, Yuetiva; Dichgans, Martin; Trojanowski, John Q.; Shaw, Leslie M.; Weiner, Michael W. und Haass, Christian
(2019):
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
In: Science Translational Medicine, Bd. 11, Nr. 507, eaav6221
Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jörge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura und Cruchaga, Carlos
(2019):
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
In: Science Translational Medicine, Bd. 11, Nr. 505, eaau2291
Baker, Emily; Sims, Rebecca; Leonenko, Ganna; Frizzati, Aura; Harwood, Janet C.; Grozeva, Detelina; Morgan, Kevin; Passmore, Peter; Holmes, Clive; Powell, John; Brayne, Carol; Gill, Michael; Mead, Simon; Bossu, Paola; Spalletta, Gianfranco; Cruchaga, Carlos; Maier, Wolfgang; Heun, Reinhard; Jessen, Frank; Peters, Oliver; Dichgans, Martin; Frölich, Lutz; Ramirez, Alfredo; Jones, Lesley; Hardy, John; Ivanov, Dobril; Hill, Matthew; Holmans, Peter; Allen, Nicholas D.; Morgan, B. Paul; Seshadri, Sudha; Schellenberg, Gerard D.; Amouyel, Philippe; Williams, Julie und Escott-Price, Valentina
(2019):
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
In: PLOS One 14(7), e0218111 [PDF, 905kB]
In: PLOS One 14(7), e0218111 [PDF, 905kB]
Pottier, Cyril; Ren, Yingxue; Perkerson, Ralph B.; Baker, Matt; Jenkins, Gregory D.; Blitterswijk, Marka van; DeJesus-Hernandez, Mariely; van Rooij, Jeroen G. J.; Murray, Melissa E.; Christopher, Elizabeth; McDonnell, Shannon K.; Fogarty, Zachary; Batzler, Anthony; Tian, Shulan; Vicente, Cristina T.; Matchett, Billie; Karydas, Anna M.; Hsiung, Ging-Yuek Robin; Seelaar, Harro; Mol, Merel O.; Finger, Elizabeth C.; Graff, Caroline; Oijerstedt, Linn; Neumann, Manuela; Heutink, Peter; Synofzik, Matthis; Wilke, Carlo; Prudlo, Johannes; Rizzu, Patrizia; Simon-Sanchez, Javier; Edbauer, Dieter; Roeber, Sigrun; Diehl-Schmid, Janine; Evers, Bret M.; King, Andrew; Mesulam, M. Marsel; Weintraub, Sandra; Geula, Changiz; Bieniek, Kevin F.; Petrucelli, Leonard; Ahern, Geoffrey L.; Reiman, Eric M.; Woodruff, Bryan K.; Caselli, Richard J.; Huey, Edward D.; Farlow, Martin R.; Grafman, Jordan; Mead, Simon; Grinberg, Lea T.; Spina, Salvatore; Grossman, Murray; Irwin, David J.; Lee, Edward B.; Suh, EunRan; Snowden, Julie; Mann, David; Ertekin-Taner, Nilufer; Uitti, Ryan J.; Wszolek, Zbigniew K.; Josephs, Keith A.; Parisi, Joseph E.; Knopman, David S.; Petersen, Ronald C.; Hodges, John R.; Piguet, Olivier; Geier, Ethan G.; Yokoyama, Jennifer S.; Rissman, Robert A.; Rogaeva, Ekaterina; Keith, Julia; Zinman, Lorne; Tartaglia, Maria Carmela; Cairns, Nigel J.; Cruchaga, Carlos; Ghetti, Bernardino; Kofler, Julia; Lopez, Oscar L.; Beach, Thomas G.; Arzberger, Thomas; Herms, Jochen; Honig, Lawrence S.; Vonsattel, Jean Paul; Halliday, Glenda M.; Kwok, John B.; White, Charles L.; Gearing, Marla; Glass, Jonathan; Rollinson, Sara; Pickering-Brown, Stuart; Rohrer, Jonathan D.; Trojanowski, John Q.; Van Deerlin, Vivianna; Bigio, Eileen H.; Troakes, Claire; Al-Sarraj, Safa; Asmann, Yan; Miller, Bruce L.; Graff-Radford, Neill R.; Boeve, Bradley F.; Seeley, William W.; Mackenzie, Ian R. A.; van Swieten, John C.; Dickson, Dennis W.; Biernacka, Joanna M. und Rademakers, Rosa
(2019):
Genome-wide analyses as part of the international FTLD-TDP whole-genome sequencing consortium reveals novel disease risk factors and increases support for immune dysfunction in FTLD.
In: Acta Neuropathologica, Bd. 137, Nr. 6: S. 879-899
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Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates A beta, tau, immunity and lipid processing.
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Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer's disease.
In: Nature Medicine, Bd. 25, Nr. 2
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Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology.
In: Molecular Neurodegeneration, Bd. 14, 1
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Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia.
In: Nature Medicine, Bd. 25, Nr. 1
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Emerging cerebrospinal fluid biomarkers in autosomal dominant Alzheimer's disease.
In: Alzheimers & Dementia, Bd. 15, Nr. 5: S. 655-665
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Effect of BDNFVal66Met on disease markers in dominantly inherited Alzheimer's disease.
In: Annals of Neurology, Bd. 84, Nr. 3: S. 424-435
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Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
In: Lancet Neurology, Bd. 17, Nr. 6: S. 548-558
Suarez-Calvet, Marc; Capell, Anja; Caballero, Miguel Angel Araque; Morenas-Rodriguez, Estrella; Fellerer, Katrin; Franzmeier, Nicolai; Kleinberger, Gernot; Eren, Erden; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Paumier, Katrina; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Jucker, Mathias; Masters, Colin L.; Rossor, Martin N.; Ringman, John M.; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
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CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
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Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
In: Nature Genetics, Bd. 50, Nr. 4: S. 524-537
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Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease.
In: Nature Genetics, Bd. 49, Nr. 9: S. 1373-1384
Carrera, Caty; Jiménez-Conde, Jordi; Derdak, Sophia; Rabionet, Kelly; Vives-Bauza, Cristofol; Soriano-Tarrega, Carolina; Giralt-Steinhauer, Eva; Mola-Caminal, Marina; Diaz-Navarro, Rosa M.; Tur, Silvia; Muiño, Elena; Gallego-Fabrega, Cristina; Beltran, Sergi; Roquer, Jaume; Ruiz, Agustin; Sotolongo-Grau, Oscar; Krupinski, Jurek; Lee, Jin-Moo; Cruchaga, Carlos; Delgado, Pilar; Malik, Rainer; Worrall, Brad B.; Seshadri, Sudha; Montaner, Joan und Fernández-Cadenas, Israel
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Whole exome sequencing analysis reveals TRPV3 as a risk factor for cardioembolic stroke.
In: Thrombosis and Haemostasis, Bd. 116, Nr. 6: S. 1165-1171
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BDNF Val66Met moderates memory impairment, hippocampal function and tau in preclinical autosomal dominant Alzheimer's disease.
In: Brain, Bd. 139: S. 2766-2777
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A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease.
In: Science Translational Medicine, Bd. 8, Nr. 341, 341ra76
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Gene-Wide Analysis Detects Two New Susceptibility Genes for Alzheimer's Disease.
In: PLOS ONE 9(6), e94661 [PDF, 1MB]
In: PLOS ONE 9(6), e94661 [PDF, 1MB]
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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer's disease.
In: PLOS ONE 5(11), e13950 [PDF, 151kB]
In: PLOS ONE 5(11), e13950 [PDF, 151kB]