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Zeitschriftenartikel
Jocher, Georg 
ORCID: https://orcid.org/0000-0002-7089-3487; Ozcelik, Gozde; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Hsia, Hung-En; Lastra Osua, Miranda; Hofmann, Laura I.; Aßfalg, Marlene; Dinkel, Lina ORCID: https://orcid.org/0000-0002-5380-3152; Feng, Xiaoqi ORCID: https://orcid.org/0000-0002-3421-220X; Schlepckow, Kai; Willem, Michael; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Tahirovic, Sabina ORCID: https://orcid.org/0000-0003-4403-9559; Blobel, Carl P. ORCID: https://orcid.org/0000-0001-5053-3137 und Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575
(2025):
The late-onset Alzheimer’s disease risk factor RHBDF2 is a modifier of microglial TREM2 proteolysis.
In: Life Science Alliance, Bd. 8, Nr. 5, e202403080
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-7089-3487; Ozcelik, Gozde; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Hsia, Hung-En; Lastra Osua, Miranda; Hofmann, Laura I.; Aßfalg, Marlene; Dinkel, Lina ORCID: https://orcid.org/0000-0002-5380-3152; Feng, Xiaoqi ORCID: https://orcid.org/0000-0002-3421-220X; Schlepckow, Kai; Willem, Michael; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Tahirovic, Sabina ORCID: https://orcid.org/0000-0003-4403-9559; Blobel, Carl P. ORCID: https://orcid.org/0000-0001-5053-3137 und Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575
(2025):
The late-onset Alzheimer’s disease risk factor RHBDF2 is a modifier of microglial TREM2 proteolysis.
In: Life Science Alliance, Bd. 8, Nr. 5, e202403080
[PDF, 2MB]
Dinkel, Lina ORCID: https://orcid.org/0000-0002-5380-3152; Hummel, Selina ORCID: https://orcid.org/0009-0001-2902-6082; Zenatti, Valerio ORCID: https://orcid.org/0009-0007-2127-6267; Malara, Mariagiovanna ORCID: https://orcid.org/0000-0001-6417-9685; Tillmann, Yannik; Colombo, Alessio; Monasor, Laura Sebastian ORCID: https://orcid.org/0000-0001-7864-7400; Suh, Jung H. ORCID: https://orcid.org/0000-0001-8119-326X; Logan, Todd ORCID: https://orcid.org/0000-0003-2081-782X; Roth, Stefan ORCID: https://orcid.org/0000-0001-6823-2981; Paeger, Lars ORCID: https://orcid.org/0000-0001-8716-3483; Hoffelner, Patricia ORCID: https://orcid.org/0009-0009-9728-8162; Bludau, Oliver ORCID: https://orcid.org/0009-0005-9426-0325; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Schifferer, Martina ORCID: https://orcid.org/0000-0002-0500-8218; Nuscher, Brigitte; Njavro, Jasenka Rudan; Prestel, Matthias; Bartos, Laura M. ORCID: https://orcid.org/0009-0007-6158-319X; Wind-Mark, Karin ORCID: https://orcid.org/0000-0002-5461-1873; Slemann, Luna; Hoermann, Leonie ORCID: https://orcid.org/0009-0006-9074-3474; Kunte, Sebastian T. ORCID: https://orcid.org/0009-0007-3543-5329; Gnörich, Johannes ORCID: https://orcid.org/0000-0003-1554-7765; Lindner, Simon ORCID: https://orcid.org/0009-0007-4379-4436; Simons, Mikael; Herms, Jochen; Paquet, Dominik ORCID: https://orcid.org/0000-0003-2065-1639; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Bartenstein, Peter ORCID: https://orcid.org/0009-0005-0734-4994; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283; Liesz, Arthur ORCID: https://orcid.org/0000-0002-9069-2594; Grosche, Antje ORCID: https://orcid.org/0000-0003-0338-7530; Bremova-Ertl, Tatiana ORCID: https://orcid.org/0000-0002-7397-045X; Catarino, Claudia ORCID: https://orcid.org/0000-0002-6528-7570; Beblo, Skadi; Bergner, Caroline; Schneider, Susanne A.; Strupp, Michael ORCID: https://orcid.org/0000-0002-9544-2279; Di Paolo, Gilbert ORCID: https://orcid.org/0000-0003-1032-1265; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843 und Tahirovic, Sabina ORCID: https://orcid.org/0000-0003-4403-9559
(2024):
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
In: Science Translational Medicine, Bd. 16, Nr. 776, eadl4616
ORCID: https://orcid.org/0000-0002-5380-3152; Hummel, Selina ORCID: https://orcid.org/0009-0001-2902-6082; Zenatti, Valerio ORCID: https://orcid.org/0009-0007-2127-6267; Malara, Mariagiovanna ORCID: https://orcid.org/0000-0001-6417-9685; Tillmann, Yannik; Colombo, Alessio; Monasor, Laura Sebastian ORCID: https://orcid.org/0000-0001-7864-7400; Suh, Jung H. ORCID: https://orcid.org/0000-0001-8119-326X; Logan, Todd ORCID: https://orcid.org/0000-0003-2081-782X; Roth, Stefan ORCID: https://orcid.org/0000-0001-6823-2981; Paeger, Lars ORCID: https://orcid.org/0000-0001-8716-3483; Hoffelner, Patricia ORCID: https://orcid.org/0009-0009-9728-8162; Bludau, Oliver ORCID: https://orcid.org/0009-0005-9426-0325; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Schifferer, Martina ORCID: https://orcid.org/0000-0002-0500-8218; Nuscher, Brigitte; Njavro, Jasenka Rudan; Prestel, Matthias; Bartos, Laura M. ORCID: https://orcid.org/0009-0007-6158-319X; Wind-Mark, Karin ORCID: https://orcid.org/0000-0002-5461-1873; Slemann, Luna; Hoermann, Leonie ORCID: https://orcid.org/0009-0006-9074-3474; Kunte, Sebastian T. ORCID: https://orcid.org/0009-0007-3543-5329; Gnörich, Johannes ORCID: https://orcid.org/0000-0003-1554-7765; Lindner, Simon ORCID: https://orcid.org/0009-0007-4379-4436; Simons, Mikael; Herms, Jochen; Paquet, Dominik ORCID: https://orcid.org/0000-0003-2065-1639; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Bartenstein, Peter ORCID: https://orcid.org/0009-0005-0734-4994; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283; Liesz, Arthur ORCID: https://orcid.org/0000-0002-9069-2594; Grosche, Antje ORCID: https://orcid.org/0000-0003-0338-7530; Bremova-Ertl, Tatiana ORCID: https://orcid.org/0000-0002-7397-045X; Catarino, Claudia ORCID: https://orcid.org/0000-0002-6528-7570; Beblo, Skadi; Bergner, Caroline; Schneider, Susanne A.; Strupp, Michael ORCID: https://orcid.org/0000-0002-9544-2279; Di Paolo, Gilbert ORCID: https://orcid.org/0000-0003-1032-1265; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843 und Tahirovic, Sabina ORCID: https://orcid.org/0000-0003-4403-9559
(2024):
Myeloid cell–specific loss of NPC1 in mice recapitulates microgliosis and neurodegeneration in patients with Niemann-Pick type C disease.
In: Science Translational Medicine, Bd. 16, Nr. 776, eadl4616
Kunze, Lea Helena; Ruch, Francois; Biechele, Gloria; Eckenweber, Florian; Wind-Mark, Karin; Dinkel, Lina; Feyen, Paul; Bartenstein, Peter; Ziegler, Sibylle; Paeger, Lars; Tahirovic, Sabina; Herms, Jochen und Brendel, Matthias
(2023):
Long-Term Pioglitazone Treatment Has No Significant Impact on Microglial Activation and Tau Pathology in P301S Mice.
In: International Journal of Molecular Sciences, Bd. 24, Nr. 12, 10106
[PDF, 1MB]
Njavro, Jasenka Rudan; Vukicevic, Marija; Fiorini, Emma; Dinkel, Lina; Mueller, Stephan A.; Berghofer, Anna; Bordier, Chiara; Kozlov, Stanislav; Halle, Annett; Buschmann, Katrin; Capell, Anja; Giudici, Camilla; Willem, Michael; Feederle, Regina; Lichtenthaler, Stefan F.; Babolin, Chiara; Montanari, Paolo; Pfeifer, Andrea; Kosco-Vilbois, Marie und Tahirovic, Sabina
(2023):
Beneficial Effect of ACI-24 Vaccination on Aβ Plaque Pathology and Microglial Phenotypes in an Amyloidosis Mouse Model.
In: Cells, Bd. 12, Nr. 1, 79
[PDF, 17MB]
Colombo, Alessio; Dinkel, Lina; Mueller, Stephan A.; Monasor, Laura Sebastian; Schifferer, Martina; Cantuti-Castelvetri, Ludovico; Koenig, Jasmin; Vidatic, Lea; Bremova-Ertl, Tatiana; Lieberman, Andrew P.; Hecimovic, Silva; Simons, Mikael; Lichtenthaler, Stefan F.; Strupp, Michael; Schneider, Susanne A. und Tahirovic, Sabina
(2021):
Loss of NPC1 enhances phagocytic uptake and impairs lipid trafficking in microglia.
In: Nature Communications, Bd. 12, Nr. 1, 1158
[PDF, 7MB]