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Anzahl der Publikationen: 33

Zeitschriftenartikel

Kavaka, Vladyslav ORCID logoORCID: https://orcid.org/0009-0004-5837-3384; Mutschler, Luisa; Rosa del Val, Clara de la ORCID logoORCID: https://orcid.org/0000-0002-1344-0844; Eglseer, Klara; Gómez Martínez, Ana M.; Flierl-Hecht, Andrea ORCID logoORCID: https://orcid.org/0000-0002-2359-1128; Ertl-Wagner, Birgit B ORCID logoORCID: https://orcid.org/0000-0002-7896-7049; Keeser, Daniel ORCID logoORCID: https://orcid.org/0000-0002-0244-1024; Mortazavi, Martin ORCID logoORCID: https://orcid.org/0000-0002-0826-7661; Seelos, Klaus ORCID logoORCID: https://orcid.org/0009-0009-0350-1293; Zimmermann, Hanna ORCID logoORCID: https://orcid.org/0000-0002-1476-3477; Haas, Jürgen ORCID logoORCID: https://orcid.org/0000-0002-2314-7465; Wildemann, Brigitte ORCID logoORCID: https://orcid.org/0000-0002-5389-3338; Kümpfel, Tania ORCID logoORCID: https://orcid.org/0000-0001-7509-5268; Dornmair, Klaus ORCID logoORCID: https://orcid.org/0000-0003-0342-5373; Korn, Thomas ORCID logoORCID: https://orcid.org/0000-0002-3633-0955; Hohlfeld, Reinhard ORCID logoORCID: https://orcid.org/0000-0002-6302-1488; Kerschensteiner, Martin ORCID logoORCID: https://orcid.org/0000-0003-4898-9383; Gerdes, Lisa Ann ORCID logoORCID: https://orcid.org/0000-0002-7053-3924 und Beltrán, Eduardo ORCID logoORCID: https://orcid.org/0000-0002-7266-4098 (2024): Twin study identifies early immunological and metabolic dysregulation of CD8 + T cells in multiple sclerosis. In: Science Immunology, Bd. 9, Nr. 99, eadj8094

Huth, Alina; Ayoub, Ikram; Barateau, Lucie; Gerdes, Lisa Ann; Severac, Dany; Krebs, Stefan; Blum, Helmut; Tumani, Hayrettin; Haas, Jürgen; Wildemann, Brigitte; Kümpfel, Tania ORCID logoORCID: https://orcid.org/0000-0001-7509-5268; Beltrán, Eduardo; Liblau, Roland S.; Dauvilliers, Yves und Dornmair, Klaus (2024): Single cell transcriptomics of cerebrospinal fluid cells from patients with recent-onset narcolepsy. In: Journal of Autoimmunity, Bd. 146, 103234 [PDF, 12MB]

Agrafiotis, Andreas; Dizerens, Raphael; Vincenti, Ilena; Wagner, Ingrid; Kuhn, Raphael; Shlesinger, Danielle; Manero-Carranza, Marcos; Cotet, Tudor-Stefan; Hong, Kai-Lin; Page, Nicolas; Fonta, Nicolas; Shammas, Ghazal; Mariotte, Alexandre; Piccinno, Margot; Kreutzfeldt, Mario; Gruntz, Benedikt; Ehling, Roy; Genovese, Alessandro; Pedrioli, Alessandro; Dounas, Andreas; Franzenburg, Soeren; Tumani, Hayrettin; Kuempfel, Tania; Kavaka, Vladyslav; Gerdes, Lisa Ann; Dornmair, Klaus; Beltran, Eduardo; Oxenius, Annette; Reddy, Sai T. T.; Merkler, Doron und Yermanos, Alexander (2023): Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS. In: Acta Neuropathologica, Bd. 145, Nr. 3: S. 335-355 [PDF, 10MB]

Kendirli, Arek; de la Rosa, Clara; Laemmle, Katrin F.; Eglseer, Klara; Bauer, Isabel J.; Kavaka, Vladyslav; Winklmeier, Stephan; Zhuo, La; Wichmann, Christian; Gerdes, Lisa Ann; Kuempfel, Tania; Dornmair, Klaus; Beltran, Eduardo; Kerschensteiner, Martin und Kawakami, Naoto (2023): A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model. In: Nature Neuroscience, Bd. 26, Nr. 10: 1713-+ [PDF, 16MB]

Wang, Zhihua; Zhang, Xi; Lu, Shu; Zhang, Chuankai; Ma, Zhe; Su, Rui; Li, Yuanfang; Sun, Ting; Li, Yutao; Hong, Mingyang; Deng, Xinyi; Monjezi, Mohammad Rafiee; Hristov, Michael; Steffens, Sabine; Santovito, Donato; Dornmair, Klaus; Ley, Klaus; Weber, Christian; Mohanta, Sarajo K.; Habenicht, Andreas J. R. und Yin, Changjun (2023): Pairing of single-cell RNA analysis and T cell antigen receptor profiling indicates breakdown of T cell tolerance checkpoints in atherosclerosis. In: Nature Cardiovascular Research, Bd. 2, Nr. 3: 290-+ [PDF, 27MB]

Cobo, Maria Fernanda Lammoglia; Welters, Carlotta; Rosenberger, Leonie; Leisegang, Matthias; Dietze, Kerstin; Pircher, Christian; Penter, Livius; Gary, Regina; Bullinger, Lars; Takvorian, Anna; Moosmann, Andreas; Dornmair, Klaus; Blankenstein, Thomas; Kammertons, Thomas; Gerbitz, Armin und Hansmann, Leo (2022): Rapid single-cell identification of Epstein-Barr virus-specific T-cell receptors for cellular therapy. In: Cytotherapy, Bd. 24, Nr. 8: S. 818-826

Welters, Carlotta; Cobo, Maria Fernanda Lammoglia; Stein, Christian Alexander; Hsu, Meng-Tung; Ben Hamza, Amin; Penter, Livius; Chen, Xiaojing; Buccitelli, Christopher; Popp, Oliver; Mertins, Philipp; Dietze, Kerstin; Bullinger, Lars; Moosmann, Andreas; Blanc, Eric; Beule, Dieter; Gerbitz, Armin; Strobel, Julian; Hackstein, Holger; Rahn, Hans-Peter; Dornmair, Klaus; Blankenstein, Thomas und Hansmann, Leo (2022): Immune Phenotypes and Target Antigens of Clonally Expanded Bone Marrow T Cells in Treatment-Naive Multiple Myeloma. In: Cancer Immunology Research, Bd. 10, Nr. 11: S. 1407-1419

Kalluri, Sudhakar Reddy; Srivastava, Rajneesh; Kenet, Selin; Tanti, Goutam K.; Dornmair, Klaus; Bennett, Jeffrey L.; Misgeld, Thomas; Hemmer, Bernhard; Wyss, Matthias T. und Herwerth, Marina (2022): P2R Inhibitors Prevent Antibody-Mediated Complement Activation in an Animal Model of Neuromyelitis Optica P2R Inhibitors Prevent Autoantibody Injury. In: Neurotherapeutics, Bd. 19, Nr. 5: S. 1603-1616 [PDF, 1MB]

Deschler, Katharina; Rademacher, Judith; Lacher, Sonja M.; Huth, Alina; Utzt, Markus; Krebs, Stefan; Blum, Helmut; Haibel, Hildrun; Proft, Fabian; Protopopov, Mikhail; Rodriguez, Valeria Rios; Beltran, Eduardo; Poddubnyy, Denis und Dornmair, Klaus (2022): Antigen-specific immune reactions by expanded CD8+T cell clones from HLA-B*27-positive patients with spondyloarthritis. In: Journal of Autoimmunity, Bd. 133, 102901

Menke, Amelie F.; Ismail, Fatme Seval; Dornmair, Klaus; Cerina, Manuela; Meuth, Sven G. und Melzer, Nico (2022): GABA(A) Receptor Autoantibodies Decrease GABAergic Synaptic Transmission in the Hippocampal CA3 Network. In: International Journal of Molecular Sciences, Bd. 23, Nr. 7, 3707 [PDF, 1MB]

Hohlfeld, Reinhard; Beltran, Eduardo; Gerdes, Lisa Ann und Dornmair, Klaus (2021): Tissue-resident CD8+ memory T cells in multiple sclerosis. In: Brain, Bd. 144, e7 [PDF, 176kB]

Hiltensperger, Michael; Beltran, Eduardo; Kant, Ravi; Tyystjarvi, Sofia; Lepennetier, Gildas; Moreno, Helena Dominguez; Bauer, Isabel J.; Grassmann, Simon; Jarosch, Sebastian; Schober, Kilian; Buchholz, Veit R.; Kenet, Selin; Gasperi, Christiane; Ollinger, Rupert; Rad, Roland; Muschaweckh, Andreas; Sie, Christopher; Aly, Lilian; Knier, Benjamin; Garg, Garima; Afzali, Ali M.; Gerdes, Lisa Ann; Kumpfel, Tania; Franzenburg, Soren; Kawakami, Naoto; Hemmer, Bernhard; Busch, Dirk H.; Misgeld, Thomas; Dornmair, Klaus und Korn, Thomas (2021): Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity. In: Nature Immunology, Bd. 22, Nr. 7: S. 880-892 [PDF, 6MB]

Braendle, Simone M.; Cerina, Manuela; Weber, Susanne; Held, Kathrin; Menke, Amelie F.; Alcala, Carmen; Gebert, David; Herrmann, Alexander M.; Pellkofer, Hannah; Gerdes, Lisa Ann; Bittner, Stefan; Leypoldt, Frank; Teegen, Bianca; Komorowski, Lars; Kuempfel, Tania; Hohlfeld, Reinhard; Meuth, Sven G.; Casanova, Bonaventura; Melzer, Nico; Beltran, Eduardo und Dornmair, Klaus (2021): Cross-reactivity of a pathogenic autoantibody to a tumor antigen in GABA(A) receptor encephalitis. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 9, e1916337118 [PDF, 1MB]

Arakawa, Akiko; Reeves, Emma; Vollmer, Sigrid; Arakawa, Yukiyasu; He, Mengwen; Galinski, Adrian; Stöhr, Julia; Dornmair, Klaus; James, Edward und Prinz, Jörg C. (2021): ERAP1 Controls the Autoimmune Response against Melanocytes in Psoriasis by Generating the Melanocyte Autoantigen and Regulating Its Amount for HLA-C*06:02 Presentation. In: Journal of Immunology, Bd. 207, Nr. 9: S. 2235-2244

Bracher, Aline; Alcalá, Carmen; Ferrer, Jaime; Melzer, Nico; Hohlfeld, Reinhard; Casanova, Bonaventura; Beltrán, Eduardo und Dornmair, Klaus (2020): An expanded parenchymal CD8+ T cell clone in GABAA receptor encephalitis. In: Annals of Clinical and Translational Neurology, Bd. 7, Nr. 2: S. 239-244 [PDF, 1MB]

Beltran, Eduardo; Paunovic, Manuela; Gebert, David; Cesur, Emine; Jeitler, Markus; Hoeftberger, Romana; Malotka, Joachim; Mader, Simone; Kawakami, Naoto; Meinl, Edgar; Bradl, Monika; Dornmair, Klaus und Lassmann, Hans (2020): Archeological neuroimmunology: resurrection of a pathogenic immune response from a historical case sheds light on human autoimmune encephalomyelitis and multiple sclerosis. In: Acta Neuropathologica, Bd. 141, Nr. 1: S. 67-83 [PDF, 4MB]

Beltran, Eduardo; Gerdes, Lisa Ann; Hansen, Julia; Flierl-Hecht, Andrea; Krebs, Stefan; Blum, Helmut; Ertl-Wagner, Birgit; Barkhof, Frederik; Kuempfel, Tania; Hohlfeld, Reinhard und Dornmair, Klaus (2019): Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis. In: Journal of Clinical Investigation, Bd. 129, Nr. 11: S. 4758-4768 [PDF, 5MB]

Penter, Livius; Dietze, Kerstin; Ritter, Julia; Cobo, Maria Fernanda Lammoglia; Garmshausen, Josefin; Aigner, Felix; Bullinger, Lars; Hackstein, Holger; Wienzek-Lischka, Sandra; Blankenstein, Thomas; Hummel, Michael; Dornmair, Klaus und Hansmann, Leo (2019): Localization-associated immune phenotypes of clonally expanded tumor-infiltrating T cells and distribution of their target antigens in rectal cancer. In: Oncoimmunology, Bd. 8, Nr. 6

Gross, Catharina C.; Meyer, Celine; Bhatia, Urvashi; Yshii, Lidia; Kleffner, Ilka; Bauer, Jan; Troscher, Anna R.; Schulte-Mecklenbeck, Andreas; Herich, Sebastian; Schneider-Hohendorf, Tilman; Plate, Henrike; Kuhlmann, Tanja; Schwaninger, Markus; Brueck, Wolfgang; Pawlitzki, Marc; Laplaud, David-Axel; Loussouarn, Delphine; Parratt, John; Barnett, Michael; Buckland, Michael E.; Hardy, Todd A.; Reddel, Stephen W.; Ringelstein, Marius; Doerr, Jan; Wildemann, Brigitte; Krämer, Markus; Lassmann, Hans; Hoeftberger, Romana; Beltran, Eduardo; Dornmair, Klaus; Schwab, Nicholas; Klotz, Luisa; Meuth, Sven G.; Martin-Blondel, Guillaume; Wiendl, Heinz und Liblau, Roland (2019): CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome. In: Nature Communications, Bd. 10, 5779 [PDF, 4MB]

Konjevic Sabolek, Matea; Held, Kathrin; Beltrán, Eduardo; Niedl, Anna G.; Meinl, Edgar; Hohlfeld, Reinhard; Lassmann, Hans und Dornmair, Klaus (2019): Communication of CD8+ T cells with mononuclear phagocytes in multiple sclerosis. In: Annals of Clinical and Translational Neurology, Bd. 6, Nr. 7: S. 1151-1164 [PDF, 3MB]

Schneider-Hohendorf, Tilman; Goerlich, Dennis; Savola, Paula; Kelkka, Tiina; Mustjoki, Satu; Gross, Catharina C.; Owens, Geoffrey C.; Klotz, Luisa; Dornmair, Klaus; Wiendl, Heinz und Schwab, Nicholas (2018): Sex bias in MHC I-associated shaping of the adaptive immune system. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 115, Nr. 9: S. 2168-2173

Arakawa, Akiko; Vollmer, Sigrid; Besgen, Petra; Galinski, Adrian; Summer, Burkhard; Kawakami, Yoshio; Wollenberg, Andreas; Dornmair, Klaus; Spannagl, Michael; Ruzicka, Thomas; Thomas, Peter und Prinz, Jörg C. (2018): Unopposed IL-36 Activity Promotes Clonal CD4(+) T-Cell Responses with IL-17A Production in Generalized Pustular Psoriasis. In: Journal of Investigative Dermatology, Bd. 138, Nr. 6: S. 1338-1347

Spadaro, Melania; Winklmeier, Stephan; Beltran, Eduardo; Macrini, Caterina; Hoeftberger, Romana; Schuh, Elisabeth; Thaler, Franziska S.; Gerdes, Lisa Ann; Laurent, Sarah; Gerhards, Ramona; Braendle, Simone; Dornmair, Klaus; Breithaupt, Constanze; Krumbholz, Markus; Moser, Markus; Krishnamoorthy, Gurumoorthy; Kamp, Frits; Jenne, Dieter; Hohlfeld, Reinhard; Kuempfel, Tania; Lassmann, Hans; Kawakami, Naoto und Meinl, Edgar (2018): Pathogenicity of human antibodies against myelin oligodendrocyte glycoprotein. In: Annals of Neurology, Bd. 84, Nr. 2: S. 315-328

Wasser, Beatrice; Pramanik, Gautam; Hess, Moritz; Klein, Matthias; Luessi, Felix; Dornmair, Klaus; Bopp, Tobias; Zipp, Frauke und Witsch, Esther (2016): Increase of Alternatively Activated Antigen Presenting Cells in Active Experimental Autoimmune Encephalomyelitis. In: Journal of Neuroimmune Pharmacology, Bd. 11, Nr. 4: S. 721-732

Gerdes, Lisa Ann; Held, Kathrin; Beltrán, Eduardo; Berking, Carola; Prinz, Jörg C.; Junker, Andreas; Tietze, Julia K.; Ertl-Wagner, Birgit; Straube, Andreas; Kümpfel, Tania; Dornmair, Klaus und Hohlfeld, Reinhard (2016): CTLA4 as Immunological Checkpoint in the Development of Multiple Sclerosis. In: Annals of Neurology, Bd. 80, Nr. 2: S. 294-300

Gross, Catharina C.; Schulte-Mecklenbeck, Andreas; Rünzi, Anna; Kuhlmann, Tanja; Posevitz-Fejfár, Anita; Schwab, Nicholas; Schneider-Hohendorf, Tilman; Herich, Sebastian; Held, Kathrin; Konjević, Matea; Hartwig, Marvin; Dornmair, Klaus; Hohlfeld, Reinhard; Ziemssen, Tjalf; Klotz, Luisa; Meuth, Sven G. und Wiendl, Heinz (2016): Impaired NK-mediated regulation of T-cell activity in multiple sclerosis is reconstituted by IL-2 receptor modulation. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 113, Nr. 21, E2973-E2982

Brändle, Simone M.; Obermeier, Birgit; Senel, Makbule; Bruder, Jessica; Mentele, Reinhard; Khademi, Mohsen; Olsson, Tomas; Tumani, Hayrettin; Kristoferitsch, Wolfgang; Lottspeich, Friedrich; Wekerle, Hartmut; Hohlfeld, Reinhard und Dornmair, Klaus (2016): Distinct oligoclonal band antibodies in multiple sclerosis recognize ubiquitous self-proteins. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 113, Nr. 28: S. 7864-7869

Hohlfeld, Reinhard; Dornmair, Klaus; Meinl, Edgar und Wekerle, Hartmut (2016): The search for the target antigens of multiple sclerosis, part 1: autoreactive CD4+T lymphocytes as pathogenic effectors and therapeutic targets. In: Lancet Neurology, Bd. 15, Nr. 2: S. 198-209

Hohlfeld, Reinhard; Dornmair, Klaus; Meinl, Edgar und Wekerle, Hartmut (2016): The search for the target antigens of multiple sclerosis, part 2: CD8+T cells, B cells, and antibodies in the focus of reverse-translational research. In: Lancet Neurology, Bd. 15, Nr. 3: S. 317-331

Schneider-Hohendorf, Tilman; Mohan, Hema; Bien, Christian G.; Breuer, Johanna; Becker, Albert; Görlich, Dennis; Kuhlmann, Tanja; Widman, Guido; Herich, Sebastian; Elpers, Christiane; Melzer, Nico; Dornmair, Klaus; Kurlemann, Gerhard; Wiendl, Heinz und Schwab, Nicholas (2016): CD8(+) T-cell pathogenicity in Rasmussen encephalitis elucidated by large-scale T-cell receptor sequencing. In: Nature Communications, Bd. 7, 11153 [PDF, 1MB]

Rühl, Geraldine; Niedl, Anna G.; Patronov, Atanas; Siewert, Katherina; Pinkert, Stefan; Kalemanov, Maria; Friese, Manuel A.; Attfield, Kathrine E.; Antes, Iris; Hohlfeld, Reinhard und Dornmair, Klaus (2016): Multiple sclerosis Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor. In: Neurology: Neuroimmunology & Neuroinflammation, Bd. 3, Nr. 4, e241 [PDF, 730kB]

Pröbstel, Anne-Katrin; Rudolf, Gabrielle; Dornmair, Klaus; Collongues, Nicolas; Chanson, Jean-Baptiste; Sanderson, Nicholas S. R.; Lindberg, Raija L. P.; Kappos, Ludwig; Seze, Jérôme de und Derfuss, Tobias (2015): Anti-MOG antibodies are present in a subgroup of patients with a neuromyelitis optica phenotype. In: Journal of Neuroinflammation 12:46 [PDF, 696kB]

Kim, Song-Min; Bhonsle, Latika; Besgen, Petra; Nickel, Jens; Backes, Anna; Held, Kathrin; Vollmer, Sigrid; Dornmair, Klaus und Prinz, Joerg C. (2012): Analysis of the paired TCR α- and β-chains of single human T cells.
In: PLOS ONE 7(5), e37338 [PDF, 476kB]

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