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Zeitschriftenartikel
Woo, Marcel S. 
ORCID: https://orcid.org/0000-0002-1306-2708; Brand, Johannes ORCID: https://orcid.org/0009-0002-5581-803X; Bal, Lukas C. ORCID: https://orcid.org/0000-0003-4731-2311; Moritz, Manuela ORCID: https://orcid.org/0000-0002-8537-7493; Walkenhorst, Mark ORCID: https://orcid.org/0000-0002-2277-9532; Vieira, Vanessa ORCID: https://orcid.org/0000-0002-0205-9669; Ipenberg, Inbal ORCID: https://orcid.org/0009-0007-6788-5009; Rothammer, Nicola ORCID: https://orcid.org/0000-0002-5137-389X; Wang, Man ORCID: https://orcid.org/0000-0002-1262-836X; Dogan, Batuhan; Loreth, Desirée ORCID: https://orcid.org/0000-0003-0827-149X; Mayer, Christina ORCID: https://orcid.org/0000-0002-4148-2822; Nagel, Darwin ORCID: https://orcid.org/0009-0003-4636-3659; Wagner, Ingrid ORCID: https://orcid.org/0000-0003-4437-9799; Pfeffer, Lena Kristina ORCID: https://orcid.org/0000-0003-3057-6492; Landgraf, Peter ORCID: https://orcid.org/0000-0003-0793-6875; van Ham, Marco ORCID: https://orcid.org/0000-0001-6819-4284; Mattern, Kuno M.-J. ORCID: https://orcid.org/0009-0007-3428-7264; Winschel, Ingo ORCID: https://orcid.org/0000-0001-9487-7070; Frantz, Noah ORCID: https://orcid.org/0000-0002-9985-457X; Sonner, Jana K. ORCID: https://orcid.org/0000-0002-4700-272X; Grosshans, Henrike K. ORCID: https://orcid.org/0000-0001-8294-5494; Miguela, Albert ORCID: https://orcid.org/0000-0002-3577-874X; Bauer, Simone ORCID: https://orcid.org/0000-0003-1780-231X; Meurs, Nina ORCID: https://orcid.org/0000-0001-5366-0123; Müller, Anke ORCID: https://orcid.org/0000-0002-6748-5706; Binkle-Ladisch, Lars ORCID: https://orcid.org/0000-0001-6168-3210; Salinas, Gabriela ORCID: https://orcid.org/0000-0001-8269-2669; Jänsch, Lothar ORCID: https://orcid.org/0000-0002-5655-1181; Dieterich, Daniela C. ORCID: https://orcid.org/0000-0002-9880-1214; Riedner, Maria ORCID: https://orcid.org/0000-0003-4421-998X; Krüger, Elke ORCID: https://orcid.org/0000-0002-2551-242X; Heppner, Frank L. ORCID: https://orcid.org/0000-0001-9816-8917; Glatzel, Markus ORCID: https://orcid.org/0000-0002-7720-8817; Puelles, Victor G. ORCID: https://orcid.org/0000-0002-7735-5462; Engler, Jan Broder ORCID: https://orcid.org/0000-0002-3169-2076; Nyengaard, Jens Randel ORCID: https://orcid.org/0000-0002-8084-4646; Misgeld, Thomas ORCID: https://orcid.org/0000-0001-9875-6794; Kerschensteiner, Martin ORCID: https://orcid.org/0000-0003-4898-9383; Merkler, Doron ORCID: https://orcid.org/0000-0002-0247-2007; Meyer-Schwesinger, Catherine ORCID: https://orcid.org/0000-0003-1511-5188 und Friese, Manuel A. ORCID: https://orcid.org/0000-0001-6380-2420
(2025):
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis.
In: Cell, Bd. 188, Nr. 17: S. 4567-4585
[PDF, 32MB]
ORCID: https://orcid.org/0000-0002-1306-2708; Brand, Johannes ORCID: https://orcid.org/0009-0002-5581-803X; Bal, Lukas C. ORCID: https://orcid.org/0000-0003-4731-2311; Moritz, Manuela ORCID: https://orcid.org/0000-0002-8537-7493; Walkenhorst, Mark ORCID: https://orcid.org/0000-0002-2277-9532; Vieira, Vanessa ORCID: https://orcid.org/0000-0002-0205-9669; Ipenberg, Inbal ORCID: https://orcid.org/0009-0007-6788-5009; Rothammer, Nicola ORCID: https://orcid.org/0000-0002-5137-389X; Wang, Man ORCID: https://orcid.org/0000-0002-1262-836X; Dogan, Batuhan; Loreth, Desirée ORCID: https://orcid.org/0000-0003-0827-149X; Mayer, Christina ORCID: https://orcid.org/0000-0002-4148-2822; Nagel, Darwin ORCID: https://orcid.org/0009-0003-4636-3659; Wagner, Ingrid ORCID: https://orcid.org/0000-0003-4437-9799; Pfeffer, Lena Kristina ORCID: https://orcid.org/0000-0003-3057-6492; Landgraf, Peter ORCID: https://orcid.org/0000-0003-0793-6875; van Ham, Marco ORCID: https://orcid.org/0000-0001-6819-4284; Mattern, Kuno M.-J. ORCID: https://orcid.org/0009-0007-3428-7264; Winschel, Ingo ORCID: https://orcid.org/0000-0001-9487-7070; Frantz, Noah ORCID: https://orcid.org/0000-0002-9985-457X; Sonner, Jana K. ORCID: https://orcid.org/0000-0002-4700-272X; Grosshans, Henrike K. ORCID: https://orcid.org/0000-0001-8294-5494; Miguela, Albert ORCID: https://orcid.org/0000-0002-3577-874X; Bauer, Simone ORCID: https://orcid.org/0000-0003-1780-231X; Meurs, Nina ORCID: https://orcid.org/0000-0001-5366-0123; Müller, Anke ORCID: https://orcid.org/0000-0002-6748-5706; Binkle-Ladisch, Lars ORCID: https://orcid.org/0000-0001-6168-3210; Salinas, Gabriela ORCID: https://orcid.org/0000-0001-8269-2669; Jänsch, Lothar ORCID: https://orcid.org/0000-0002-5655-1181; Dieterich, Daniela C. ORCID: https://orcid.org/0000-0002-9880-1214; Riedner, Maria ORCID: https://orcid.org/0000-0003-4421-998X; Krüger, Elke ORCID: https://orcid.org/0000-0002-2551-242X; Heppner, Frank L. ORCID: https://orcid.org/0000-0001-9816-8917; Glatzel, Markus ORCID: https://orcid.org/0000-0002-7720-8817; Puelles, Victor G. ORCID: https://orcid.org/0000-0002-7735-5462; Engler, Jan Broder ORCID: https://orcid.org/0000-0002-3169-2076; Nyengaard, Jens Randel ORCID: https://orcid.org/0000-0002-8084-4646; Misgeld, Thomas ORCID: https://orcid.org/0000-0001-9875-6794; Kerschensteiner, Martin ORCID: https://orcid.org/0000-0003-4898-9383; Merkler, Doron ORCID: https://orcid.org/0000-0002-0247-2007; Meyer-Schwesinger, Catherine ORCID: https://orcid.org/0000-0003-1511-5188 und Friese, Manuel A. ORCID: https://orcid.org/0000-0001-6380-2420
(2025):
The immunoproteasome disturbs neuronal metabolism and drives neurodegeneration in multiple sclerosis.
In: Cell, Bd. 188, Nr. 17: S. 4567-4585
[PDF, 32MB]
Zhang, Brian C.; Schneider-Hohendorf, Tilman ORCID: https://orcid.org/0000-0002-3717-5176; Elyanow, Rebecca; Pignolet, Beatrice; Falk, Simon; Wünsch, Christian; Deffner, Marie; Yusko, Erik; May, Damon; Mattox, Daniel ORCID: https://orcid.org/0000-0002-2089-1993; Dawin, Eva; Gerdes, Lisa Ann ORCID: https://orcid.org/0000-0002-7053-3924; Bucciarelli, Florence; Revie, Lisa; Antony, Gisela; Jarius, Sven; Seidel, Christiane; Senel, Makbule; Bittner, Stefan ORCID: https://orcid.org/0000-0003-2179-3655; Luessi, Felix ORCID: https://orcid.org/0000-0003-4334-4199; Havla, Joachim ORCID: https://orcid.org/0000-0002-4386-1340; Knop, Matthias; Friese, Manuel A.; Rothacher, Susanne; Salmen, Anke ORCID: https://orcid.org/0000-0002-4751-299X; Hayashi, Fumie ORCID: https://orcid.org/0000-0002-7754-3770; Henry, Roland; Caillier, Stacy; Santaniello, Adam; Alexander, Jessa; Bove, Riley; Baranzini, Sergio; Cree, Bruce A.C.; Caverzasi, Eduardo; Cuneo, Richard; Caillier, Stacy J.; Cooper, Tiffany; Green, Ari J.; Guo, Chu-Yueh; Gelfand, Jeffrey M.; Gomez, Refujia; Gupta, Sasha; Hollenbach, Jill; Harms, Meagan; Henry, Roland G.; Hauser, Stephen L.; Mendoza, Myra; Oksenberg, Jorge R.; Papinutto, Nico; Pleasure, Sam; Santaniello, Adam; Sabatino, Joseph J.; Stern, William A.; Wilson, Michael R.; Zamvil, Scott; Aktas, Orhan; Giede-Jeppe, Antje; Gisevius, Barbara; Kowarik, Markus; Paul, Friedemann; Rothhammer, Veit; Trebst, Corinna; Zettl, Uwe; Seipelt, Maria; Heesen, Christoph; Nischwitz, Sandra; Bayas, Antonios; Tumani, Hayrettin ORCID: https://orcid.org/0000-0002-1647-6201; Then Bergh, Florian; Meyer zu Hörste, Gerd; Kümpfel, Tania ORCID: https://orcid.org/0000-0001-7509-5268; Gross, Catharina C.; Wildemann, Brigitte; Kerschensteiner, Martin; Gold, Ralf; Meuth, Sven G.; Zipp, Frauke ORCID: https://orcid.org/0000-0002-1231-1928; Cree, Bruce A.C.; Oksenberg, Jorge; Wilson, Michael R. ORCID: https://orcid.org/0000-0002-8705-5084; Hauser, Stephen L.; Zamvil, Scott S.; Klotz, Luisa; Liblau, Roland ORCID: https://orcid.org/0000-0001-5477-5475; Robins, Harlan; Sabatino, Joseph J. ORCID: https://orcid.org/0000-0002-6804-7441; Wiendl, Heinz und Schwab, Nicholas ORCID: https://orcid.org/0000-0001-5494-9885
(2025):
HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis.
In: eBioMedicine, Bd. 118, 105873
[PDF, 7MB]
ORCID: https://orcid.org/0000-0002-3717-5176; Elyanow, Rebecca; Pignolet, Beatrice; Falk, Simon; Wünsch, Christian; Deffner, Marie; Yusko, Erik; May, Damon; Mattox, Daniel ORCID: https://orcid.org/0000-0002-2089-1993; Dawin, Eva; Gerdes, Lisa Ann ORCID: https://orcid.org/0000-0002-7053-3924; Bucciarelli, Florence; Revie, Lisa; Antony, Gisela; Jarius, Sven; Seidel, Christiane; Senel, Makbule; Bittner, Stefan ORCID: https://orcid.org/0000-0003-2179-3655; Luessi, Felix ORCID: https://orcid.org/0000-0003-4334-4199; Havla, Joachim ORCID: https://orcid.org/0000-0002-4386-1340; Knop, Matthias; Friese, Manuel A.; Rothacher, Susanne; Salmen, Anke ORCID: https://orcid.org/0000-0002-4751-299X; Hayashi, Fumie ORCID: https://orcid.org/0000-0002-7754-3770; Henry, Roland; Caillier, Stacy; Santaniello, Adam; Alexander, Jessa; Bove, Riley; Baranzini, Sergio; Cree, Bruce A.C.; Caverzasi, Eduardo; Cuneo, Richard; Caillier, Stacy J.; Cooper, Tiffany; Green, Ari J.; Guo, Chu-Yueh; Gelfand, Jeffrey M.; Gomez, Refujia; Gupta, Sasha; Hollenbach, Jill; Harms, Meagan; Henry, Roland G.; Hauser, Stephen L.; Mendoza, Myra; Oksenberg, Jorge R.; Papinutto, Nico; Pleasure, Sam; Santaniello, Adam; Sabatino, Joseph J.; Stern, William A.; Wilson, Michael R.; Zamvil, Scott; Aktas, Orhan; Giede-Jeppe, Antje; Gisevius, Barbara; Kowarik, Markus; Paul, Friedemann; Rothhammer, Veit; Trebst, Corinna; Zettl, Uwe; Seipelt, Maria; Heesen, Christoph; Nischwitz, Sandra; Bayas, Antonios; Tumani, Hayrettin ORCID: https://orcid.org/0000-0002-1647-6201; Then Bergh, Florian; Meyer zu Hörste, Gerd; Kümpfel, Tania ORCID: https://orcid.org/0000-0001-7509-5268; Gross, Catharina C.; Wildemann, Brigitte; Kerschensteiner, Martin; Gold, Ralf; Meuth, Sven G.; Zipp, Frauke ORCID: https://orcid.org/0000-0002-1231-1928; Cree, Bruce A.C.; Oksenberg, Jorge; Wilson, Michael R. ORCID: https://orcid.org/0000-0002-8705-5084; Hauser, Stephen L.; Zamvil, Scott S.; Klotz, Luisa; Liblau, Roland ORCID: https://orcid.org/0000-0001-5477-5475; Robins, Harlan; Sabatino, Joseph J. ORCID: https://orcid.org/0000-0002-6804-7441; Wiendl, Heinz und Schwab, Nicholas ORCID: https://orcid.org/0000-0001-5494-9885
(2025):
HLA-A∗03:01 as predictive genetic biomarker for glatiramer acetate treatment response in multiple sclerosis: a retrospective cohort analysis.
In: eBioMedicine, Bd. 118, 105873
[PDF, 7MB]
Kapell, Hannah; Fazio, Luca; Dyckow, Julia; Schwarz, Sophia; Cruz-Herranz, Andres; Mayer, Christina; Campos, Joaquin; D'Este, Elisa; Moebius, Wiebke; Cordano, Christian; Probstel, Anne-Katrin; Gharagozloo, Marjan; Zulji, Amel; Naik, Venu Narayanan; Delank, Anna; Cerina, Manuela; Muentefering, Thomas; Lerma-Martin, Celia; Sonner, Jana K.; Sin, Jung Hyung; Disse, Paul; Rychlik, Nicole; Sabeur, Khalida; Chavali, Manideep; Srivastava, Rajneesh; Heidenreich, Matthias; Fitzgerald, Kathryn C.; Seebohm, Guiscard; Stadelmann, Christine; Hemmer, Bernhard; Platten, Michael; Jentsch, Thomas J.; Engelhardt, Maren; Budde, Thomas; Nave, Klaus-Armin; Calabresi, Peter A.; Friese, Manuel A.; Green, Ari J.; Acuna, Claudio; Rowitch, David H.; Meuth, Seven G. und Schirmer, Lucas
(2023):
Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against.
In: Journal of Clinical Investigation, Bd. 133, Nr. 7, e164223
[PDF, 4MB]
Duerr, Marc; Nissen, Gunnar; Suehs, Kurt-Wolfram; Schwenkenbecher, Philipp; Geis, Christian; Ringelstein, Marius; Hartung, Hans-Peter; Friese, Manuel A.; Kaufmann, Max; Malter, Michael P.; Madlener, Marie; Thaler, Franziska S.; Kuempfel, Tania; Senel, Makbule; Haeusler, Martin G.; Schneider, Hauke; Bergh, Florian Then; Kellinghaus, Christoph; Zettl, Uwe K.; Wandinger, Klaus-Peter; Melzer, Nico; Gross, Catharina C.; Lange, Peter; Dreyhaupt, Jens; Tumani, Hayrettin; Leypoldt, Frank und Lewerenz, Jan
(2021):
CSF Findings in Acute NMDAR and LGI1 Antibody-Associated Autoimmune Encephalitis.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 8, Nr. 6, e1086
Ostkamp, Patrick; Salmen, Anke; Pignolet, Beatrice; Görlich, Dennis; Andlauer, Till F. M.; Schulte-Mecklenbeck, Andreas; Gonzalez-Escamilla, Gabriel; Bucciarelli, Florence; Gennero, Isabelle; Breuer, Johanna; Antony, Gisela; Schneider-Hohendorf, Tilman; Mykicki, Nadine; Bayas, Antonios; Bergh, Florian Then; Bittner, Stefan; Hartung, Hans-Peter; Friese, Manuel A.; Linker, Ralf A.; Luessi, Felix; Lehmann-Horn, Klaus; Mühlau, Mark; Paul, Friedemann; Stangel, Martin; Tackenberg, Björn; Tumani, Hayrettin; Warnke, Clemens; Weber, Frank; Wildemann, Brigitte; Zettl, Uwe K.; Ziemann, Ulf; Müller-Myhsok, Bertram; Kümpfel, Tania; Klotz, Luisa; Meuth, Sven G.; Zipp, Frauke; Hemmer, Bernhard; Hohlfeld, Reinhard; Brassat, David; Gold, Ralf; Gross, Catharina C.; Lukas, Carsten; Groppa, Sergiu; Loser, Karin; Wiendl, Heinz und Schwab, Nicholas
(2021):
Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 1, e2018457118
[PDF, 2MB]
Schwenkenbecher, Philipp; Skripuletz, Thomas; Lange, Peter; Durr, Marc; Konen, Felix F.; Mohn, Nora; Ringelstein, Marius; Menge, Til; Friese, Manuel A.; Melzer, Nico; Malter, Michael P.; Hausler, Martin; Thaler, Franziska S.; Stangel, Martin; Lewerenz, Jan und Suhs, Kurt-Wolfram
(2021):
Intrathecal Antibody Production Against Epstein-Barr, Herpes Simplex, and Other Neurotropic Viruses in Autoimmune Encephalitis.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 8, Nr. 6, e1062
Er-Lukowiak, Marco; Duan, Yinghui; Rassendren, Francois; Ulmann, Lauriane; Nicke, Annette; Ufer, Friederike; Friese, Manuel A.; Koch-Nolte, Friedrich; Magnus, Tim und Rissiek, Björn
(2020):
A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice.
In: Iscience, Bd. 23, Nr. 12, 101870
Gasperi, Christiane; Andlauer, Till F. M.; Keating, Ana; Knier, Benjamin; Klein, Ana; Pernpeintner, Verena; Lichtner, Peter; Gold, Ralf; Zipp, Frauke; Bergh, Florian Then; Stangel, Martin; Tumani, Hayrettin; Wildemann, Brigitte; Wiendl, Heinz; Bayas, Antonios; Kuempfel, Tania; Zettl, Uwe K.; Linker, Ralf A.; Ziemann, Ulf; Knop, Matthias; Warnke, Clemens; Friese, Manuel A.; Paul, Friedemann; Tackenberg, Björn; Berthele, Achim und Hemmer, Bernhard
(2020):
Genetic determinants of the humoral immune response in MS.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 7, Nr. 5, e827
[PDF, 379kB]
van der Lee, Sven J.; Conway, Olivia J.; Jansen, Iris; Carrasquillo, Minerva M.; Kleineidam, Luca; van den Akker, Erik; Hernandez, Isabel; van Eijk, Kristel R.; Stringa, Najada; Chen, Jason A.; Zettergren, Anna; Andlauer, Till F. M.; Diez-Fairen, Monica; Simon-Sanchez, Javier; Lleo, Alberto; Zetterberg, Henrik; Nygaard, Marianne; Blauwendraat, Cornelis; Savage, Jeanne E.; Mengel-From, Jonas; Moreno-Grau, Sonia; Wagner, Michael; Fortea, Juan; Keogh, Michael J.; Blennow, Kaj; Skoog, Ingmar; Friese, Manuel A.; Pletnikova, Olga; Zulaica, Miren; Lage, Carmen; de Rojas, Itziar; Riedel-Heller, Steffi; Illan-Gala, Ignacio; Wei, Wei; Jeune, Bernard; Orellana, Adelina; Bergh, Florian Then; Wang, Xue; Hulsman, Marc; Beker, Nina; Tesi, Niccolo; Morris, Christopher M.; Indakoetxea, Begona; Collij, Lyduine E.; Scherer, Martin; Morenas-Rodriguez, Estrella; Ironside, James W.; van Berckel, Bart N. M.; Alcolea, Daniel; Wiendl, Heinz; Strickland, Samantha L.; Pastor, Pau; Rodriguez Rodriguez, Eloy; Boeve, Bradley F.; Petersen, Ronald C.; Ferman, Tanis J.; van Gerpen, Jay A.; Reinders, Marcel J. T.; Uitti, Ryan J.; Tarraga, Lluis; Maier, Wolfgang; Dols-Icardo, Oriol; Kawalia, Amit; Dalmasso, Maria Carolina; Boada, Merce; Zettl, Uwe K.; van Schoor, Natasja M.; Beekman, Marian; Allen, Mariet; Masliah, Eliezer; Lopez de Munain, Adolfo; Pantelyat, Alexander; Wszolek, Zbigniew K.; Ross, Owen A.; Dickson, Dennis W.; Graff-Radford, Neill R.; Knopman, David; Rademakers, Rosa; Lemstra, Afina W.; Pijnenburg, Yolande A. L.; Scheltens, Philip; Gasser, Thomas; Chinnery, Patrick F.; Hemmer, Bernhard; Huisman, Martijn A.; Troncoso, Juan; Moreno, Fermin; Nohr, Ellen A.; Sorensen, Thorkild I. A.; Heutink, Peter; Sanchez-Juan, Pascual; Posthuma, Danielle; Clarimon, Jordi; Christensen, Kaare; Ertekin-Taner, Nilufer; Scholz, Sonja W.; Ramirez, Alfredo; Ruiz, Agustin; Slagboom, Eline; van der Flier, Wiesje M. und Holstege, Henne
(2019):
A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
In: Acta Neuropathologica, Bd. 138, Nr. 2: S. 237-250
[PDF, 1MB]
Rühl, Geraldine; Niedl, Anna G.; Patronov, Atanas; Siewert, Katherina; Pinkert, Stefan; Kalemanov, Maria; Friese, Manuel A.; Attfield, Kathrine E.; Antes, Iris; Hohlfeld, Reinhard und Dornmair, Klaus
(2016):
Multiple sclerosis Molecular mimicry of an antimyelin HLA class I restricted T-cell receptor.
In: Neurology: Neuroimmunology & Neuroinflammation, Bd. 3, Nr. 4, e241
[PDF, 730kB]