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Anzahl der Publikationen: 11
Zeitschriftenartikel
Trambauer, Johannes; Rodríguez Sarmiento, Rosa María; Fukumori, Akio; Feederle, Regina; Baumann, Karlheinz und Steiner, Harald
(2020):
Aβ43‐producing PS1 FAD mutants cause altered substrate interactions and respond to γ‐secretase modulation.
In: Embo Reports, Bd. 21, Nr. 1, e47996
[PDF, 1MB]
Trambauer, Johannes; Fukumori, Akio und Steiner, Harald
(2020):
Pathogenic A beta generation in familial Alzheimer's disease: novel mechanistic insights and therapeutic implications.
In: Current Opinion in Neurobiology, Bd. 61: S. 73-81
Fukumori, Akio; Feilen, Lukas P. und Steiner, Harald
(2020):
Substrate recruitment by gamma-secretase.
In: Seminars in Cell & Developmental Biology, Bd. 105: S. 54-63
Mentrup, Torben; Theodorou, Kosta; Cabrera-Cabrera, Florencia; Hethig, Andreas O.; Happ, Kathrin; Gijbels, Marion; Gradtke, Ann-Christine; Rabe, Björn; Fukumori, Akio; Steiner, Harald; Tholey, Andreas; Fluhrer, Regina; Donners, Marjo und Schröder, Bernd
(2019):
Atherogenic LOX-1 signaling is controlled by SPPL2-mediated intramembrane proteolysis.
In: Journal of Experimental Medicine, Bd. 216, Nr. 4: S. 807-830
Schlepckow, Kai; Kleinberger, Gernot; Fukumori, Akio; Feederle, Regina; Lichtenthaler, Stefan F.; Steiner, Harald und Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365
[PDF, 1MB]
Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
[PDF, 1MB]
Fukumori, Akio und Steiner, Harald
(2016):
Substrate recruitment of gamma-secretase and mechanism of clinical presenilin mutations revealed by photoaffinity mapping.
In: Embo Journal, Bd. 35, Nr. 15: S. 1628-1643
Kretner, Benedikt; Trambauer, Johannes; Fukumori, Akio; Mielke, Janina; Kuhn, Peer-Hendrik; Kremmer, Elisabeth; Giese, Armin; Lichtenthaler, Stefan F.; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas und Steiner, Harald
(2016):
Generation and deposition of A43 by the virtually inactive presenilin-1 L435F mutant contradicts the presenilin loss-of-function hypothesis of Alzheimer's disease.
In: Embo Molecular Medicine, Bd. 8, Nr. 5: S. 458-465
Fleck, Daniel; Voss, Matthias; Brankatschk, Ben; Giudici, Camilla; Hampel, Heike; Schwenk, Benjamin; Edbauer, Dieter; Fukumori, Akio; Steiner, Harald; Kremmer, Elisabeth; Haug-Kröper, Martina; Rossner, Moritz J.; Fluhrer, Regina; Willem, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
In: Journal of Biological Chemistry, Bd. 291, Nr. 1: S. 318-333
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Proteolytic Processing of Neuregulin 1 Type III by Three Intramembrane-cleaving Proteases.
In: Journal of Biological Chemistry, Bd. 291, Nr. 1: S. 318-333
Hüttl, Susann; Helfrich, Felix; Mentrup, Torben; Held, Sebastian; Fukumori, Akio; Steiner, Harald; Saftig, Paul; Fluhrer, Regina und Schröder, Bernd
(2016):
Substrate determinants of signal peptide peptidase-like 2a (SPPL2a)-mediated intramembrane proteolysis of the invariant chain CD74.
In: Biochemical Journal, Bd. 473: S. 1405-1422
Itoh, Naohiro; Okochi, Masayasu; Tagami, Shinji; Nishitomi, Kouhei; Nakayama, Taisuke; Yanagida, Kanta; Fukumori, Akio; Jiang, Jingwei; Mori, Kohji; Hosono, Motoko; Kikuchi, Jyunko; Nakano, Yuko; Takinami, Yoshihiko; Dohi, Keiji; Nishigaki, Atsuko; Takemoto, Hiroshi; Minagawa, Kazuyuki; Katoh, Takaaki; Willem, Michael; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Morihara, Takashi; Tanaka, Toshihisa; Kudo, Takashi; Hasegawa, Hiroshi; Nishimura, Masaki; Sakaguchi, Gaku; Kato, Akira und Takeda, Masatoshi
(2009):
Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor.
In: Neurodegenerative Diseases, Nr. 5-6: S. 230-239
[PDF, 556kB]
ORCID: https://orcid.org/0000-0002-4869-1627; Morihara, Takashi; Tanaka, Toshihisa; Kudo, Takashi; Hasegawa, Hiroshi; Nishimura, Masaki; Sakaguchi, Gaku; Kato, Akira und Takeda, Masatoshi
(2009):
Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor.
In: Neurodegenerative Diseases, Nr. 5-6: S. 230-239
[PDF, 556kB]