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Anzahl der Publikationen: 18
Zeitschriftenartikel
Kaji, Seiji; Berghoff, Stefan A.; Spieth, Lena; Schlaphoff, Lennart; Sasmita, Andrew O.; Vitale, Simona; Büschgens, Luca; Kedia, Shreeya; Zirngibl, Martin; Nazarenko, Taisiia; Damkou, Alkmini; Hosang, Leon; Depp, Constanze; Kamp, Frits; Scholz, Patricia; Ewers, David; Giera, Martin; Ischebeck, Till; Wurst, Wolfgang 
ORCID: https://orcid.org/0000-0003-4422-7410; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Schifferer, Martina ORCID: https://orcid.org/0000-0002-0500-8218; Willem, Michael; Nave, Klaus-Armin; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas; Jäkel, Sarah; Wirths, Oliver ORCID: https://orcid.org/0000-0002-4115-0334; Saher, Gesine ORCID: https://orcid.org/0000-0003-3507-9604 und Simons, Mikael ORCID: https://orcid.org/0000-0001-5329-192X
(2024):
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis.
In: Immunity, Bd. 57, Nr. 11: S. 2651-2668
[PDF, 11MB]
ORCID: https://orcid.org/0000-0003-4422-7410; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Schifferer, Martina ORCID: https://orcid.org/0000-0002-0500-8218; Willem, Michael; Nave, Klaus-Armin; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas; Jäkel, Sarah; Wirths, Oliver ORCID: https://orcid.org/0000-0002-4115-0334; Saher, Gesine ORCID: https://orcid.org/0000-0003-3507-9604 und Simons, Mikael ORCID: https://orcid.org/0000-0001-5329-192X
(2024):
Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis.
In: Immunity, Bd. 57, Nr. 11: S. 2651-2668
[PDF, 11MB]
Hu, Yiying; Hruscha, Alexander; Pan, Chenchen; Schifferer, Martina; Schmidt, Michael K.; Nuscher, Brigitte ORCID: https://orcid.org/0009-0000-4661-0742; Giera, Martin; Kostidis, Sarantos; Burhan, Özge; Bebber, Frauke van; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Arzberger, Thomas; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Schmid, Bettina ORCID: https://orcid.org/0000-0001-8043-7269
(2024):
Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.
In: Molecular Neurodegeneration, Bd. 19, 50
[PDF, 6MB]
ORCID: https://orcid.org/0009-0000-4661-0742; Giera, Martin; Kostidis, Sarantos; Burhan, Özge; Bebber, Frauke van; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Arzberger, Thomas; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Schmid, Bettina ORCID: https://orcid.org/0000-0001-8043-7269
(2024):
Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits.
In: Molecular Neurodegeneration, Bd. 19, 50
[PDF, 6MB]
Dawkins, Edgar; Derks, Rico J. E.; Schifferer, Martina; Trambauer, Johannes; Winkler, Edith; Simons, Mikael; Paquet, Dominik; Giera, Martin; Kamp, Frits und Steiner, Harald
(2023):
Membrane lipid remodeling modulates γ-secretase processivity.
In: Journal of Biological Chemistry, Bd. 299, Nr. 4, 103027
[PDF, 2MB]
Spix, Barbara; Butz, Elisabeth S.; Chen, Cheng-Chang; Rosato, Anna Scotto; Tang, Rachel; Jeridi, Aicha; Kudrina, Veronika; Plesch, Eva; Wartenberg, Philipp; Arlt, Elisabeth; Briukhovetska, Daria; Ansari, Meshal; Günsel, Gizem Günes; Conlon, Thomas M.; Wyatt, Amanda; Wetzel, Sandra; Teupser, Daniel; Holdt, Lesca M.; Ectors, Fabien; Boekhoff, Ingrid; Boehm, Ulrich; García-Añoveros, Jaime; Saftig, Paul; Giera, Martin; Kobold, Sebastian; Schiller, Herbert B.; Zierler, Susanna; Gudermann, Thomas; Wahl-Schott, Christian; Bracher, Franz; Yildirim, Ali Önder; Biel, Martin und Grimm, Christian
(2022):
Lung emphysema and impaired macrophage elastase clearance in mucolipin 3 deficient mice.
In: Nature Communications, Bd. 13, 318
[PDF, 3MB]
Mueller, Christoph; Hank, Emily; Giera, Martin und Bracher, Franz
(2022):
Dehydrocholesterol Reductase 24 (DHCR24): Medicinal Chemistry, Pharmacology and Novel Therapeutic Options.
In: Current Medicinal Chemistry, Bd. 29, Nr. 23: S. 4005-4025
Bouwknegt, Jonna; Wiersma, Sanne J.; Ortiz-Merino, Raul A.; Doornenbal, Eline S. R.; Buitenhuis, Petrik; Giera, Martin; Mueller, Christoph und Pronk, Jack T.
(2021):
A squalene-hopene cyclase in Schizosaccharomyces japonicus represents a eukaryotic adaptation to sterol-limited anaerobic environments.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 118, Nr. 32, e2105225118
Colombo, Alessio Vittorio; Sadler, Rebecca Katie; Llovera, Gemma; Singh, Vikramjeet; Roth, Stefan; Heindl, Steffanie; Monasor, Laura Sebastian; Verhoeven, Aswin; Peters, Finn; Parhizkar, Samira; Kamp, Frits; de Aguero, Mercedes Gomez; MacPherson, Andrew J.; Winkler, Edith; Herms, Jochen; Benakis, Corinne; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Steiner, Harald; Giera, Martin; Haass, Christian; Tahirovic, Sabina und Liesz, Arthur
(2021):
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.
In: eLife, Bd. 10, e59826
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-0654-387X; Steiner, Harald; Giera, Martin; Haass, Christian; Tahirovic, Sabina und Liesz, Arthur
(2021):
Microbiota-derived short chain fatty acids modulate microglia and promote Aβ plaque deposition.
In: eLife, Bd. 10, e59826
[PDF, 2MB]
Murenu, Elisa; Kostidis, Sarantos; Lahiri, Shibojyoti; Geserich, Anna S.; Imhof, Axel; Giera, Martin und Michalakis, Stylianos
(2021):
Metabolic Analysis of Vitreous/Lens and Retina in Wild Type and Retinal Degeneration Mice.
In: International Journal of Molecular Sciences, Bd. 22, Nr. 5, 2345
Traube, Franziska R.; Ozdemir, Dilara; Sahin, Hanife; Scheel, Constanze; Glück, Andrea F.; Geserich, Anna S.; Oganesian, Sabine; Kostidis, Sarantos; Iwan, Katharina; Rahimoff, Rene; Giorgio, Grazia; Mueller, Markus; Spada, Fabio; Biel, Martin; Cox, Juergen; Giera, Martin; Michalakis, Stylianos und Carell, Thomas
(2021):
Redirected nuclear glutamate dehydrogenase supplies Tet3 with alpha-ketoglutarate in neurons.
In: Nature Communications, Bd. 12, Nr. 1, 4100
Kong, Li; Dawkins, Edgar; Campbell, Frederick; Winkler, Edith; Derks, Rico J. E.; Giera, Martin; Kamp, Frits; Steiner, Harald und Kros, Alexander
(2020):
Photo-controlled delivery of very long chain fatty acids to cell membranes and modulation of membrane protein function.
In: Biochimica et Biophysica Acta-Biomembranes, Bd. 1862, Nr. 5, 183200
Sadler, Rebecca; Cramer, Julia V.; Heindl, Steffanie; Kostidis, Sarantos; Betz, Dene; Zuurbier, Kielen R.; Northoff, Bernd H.; Heijink, Marieke; Goldberg, Mark P.; Plautz, Erik J.; Roth, Stefan; Malik, Rainer; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Holdt, Lesca M.; Benakis, Corinne; Giera, Martin; Stowe, Ann M. und Liesz, Arthur
(2020):
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
In: Journal of Neuroscience, Bd. 40, Nr. 5: S. 1162-1173
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-0654-387X; Holdt, Lesca M.; Benakis, Corinne; Giera, Martin; Stowe, Ann M. und Liesz, Arthur
(2020):
Short-Chain Fatty Acids Improve Poststroke Recovery via Immunological Mechanisms.
In: Journal of Neuroscience, Bd. 40, Nr. 5: S. 1162-1173
[PDF, 2MB]
Müller, Christoph; Junker, Julia; Bracher, Franz und Giera, Martin
(2019):
A gas chromatography-mass spectrometry-based whole-cell screening assay for target identification in distal cholesterol biosynthesis.
In: Nature Protocols, Bd. 14, Nr. 8: S. 2546-2570
Junker, Julia; Chong, Isabelle; Kamp, Frits; Steiner, Harald; Giera, Martin; Müller, Christoph und Bracher, Franz
(2019):
Comparison of Strategies for the Determination of Sterol Sulfates via GC-MS Leading to a Novel Deconjugation-Derivatization Protocol.
In: Molecules, Bd. 24, Nr. 13, 2353
Koerner, Andreas; Zhou, Enchen; Muller, Christoph; Mohammed, Yassene; Herceg, Sandra; Bracher, Franz; Rensen, Patrick C. N.; Wang, Yanan; Mirakaj, Valbona und Giera, Martin
(2019):
Inhibition of Delta 24-dehydrocholesterol reductase activates pro-resolving lipid mediator biosynthesis and inflammation resolution.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 116, Nr. 41: S. 20623-20634
Hubler, Zita; Allimuthu, Dharmaraja; Bederman, Ilya; Elitt, Matthew S.; Madhavan, Mayur; Allan, Kevin C.; Shick, H. Elizabeth; Garrison, Eric; Karl, Molly T.; Factor, Daniel C.; Nevin, Zachary S.; Sax, Joel L.; Thompson, Matthew A.; Fedorov, Yuriy; Jin, Jing; Wilson, William K.; Giera, Martin; Bracher, Franz; Miller, Robert H.; Tesar, Paul J. und Adams, Drew J.
(2018):
Accumulation of 8,9-unsaturated sterols drives oligodendrocyte formation and remyelination.
In: Nature, Bd. 560, Nr. 7718: S. 372-376
Müller, Christoph; Hemmers, Sandra; Bartl, Nicholas; Plodek, Alois; Körner, Andreas; Mirakaj, Valbona; Giera, Martin und Bracher, Franz
(2017):
New chemotype of selective and potent inhibitors of human delta 24-dehydrocholesterol reductase.
In: European Journal of Medicinal Chemistry, Bd. 140: S. 305-320
Müller, Christoph; Binder, Ulrike; Bracher, Franz und Giera, Martin
(2017):
Antifungal drug testing by combining minimal inhibitory concentration testing with target identification by gas chromatography-mass spectrometry.
In: Nature Protocols, Bd. 12, Nr. 5: S. 947-963
Knappmann, Inga; Lehmkuhl, Kirstin; Köhler, Jens; Schepmann, Dirk; Giera, Martin; Bracher, Franz und Wünsch, Bernhard
(2017):
Lipase-catalyzed kinetic resolution as key step in the synthesis of enantiomerically pure a ligands with 2-benzopyran structure.
In: Bioorganic & Medicinal Chemistry, Bd. 25, Nr. 13: S. 3384-3395