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Anzahl der Publikationen: 10
Zeitschriftenartikel
Ko, Suk Kyu; Berner, Carolin; Kulakova, Alina; Schneider, Markus; Antes, Iris; Winter, Gerhard; Harris, Pernille und Peters, Gunther H. J.
(2022):
Investigation of the pH-dependent aggregation mechanisms of GCSF using low resolution protein characterization techniques and advanced molecular dynamics simulations.
In: Computational and Structural Biotechnology Journal, Bd. 20: S. 1439-1455
Domnowski, Martin; Maruno, Takahiro; Enomoto, Kanta; Kummer, Felix; Kulakova, Alina; Harris, Pernille; Uchiyama, Susumu; Jaehrling, Jan und Friess, Wolfgang
(2021):
A Multi-Method Approach to Assess the Self-Interaction Behavior of Infliximab.
In: Journal of Pharmaceutical Sciences, Bd. 110, Nr. 5: S. 1979-1988
Mahapatra, Sujata; Polimeni, Marco; Gentiluomo, Lorenzo; Roessner, Dierk; Friess, Wolfgang; Peters, Guenther H. J.; Streicher, Werner W.; Lund, Mikael und Harris, Pernille
(2021):
Self-Interactions of Two Monoclonal Antibodies: Small-Angle X-ray Scattering, Light Scattering, and Coarse-Grained Modeling.
In: Molecular Pharmaceutics, Bd. 19, Nr. 2: S. 508-519
Svilenov, Hristo 
ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Zalar, Matja; Golovanov, Alexander P.; Harris, Pernille und Winter, Gerhard
(Januar 2020):
Orthogonal Techniques to Study the Effect of pH, Sucrose, and Arginine Salts on Monoclonal Antibody Physical Stability and Aggregation During Long-Term Storage.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 584-594
[PDF, 2MB]
ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Zalar, Matja; Golovanov, Alexander P.; Harris, Pernille und Winter, Gerhard
(Januar 2020):
Orthogonal Techniques to Study the Effect of pH, Sucrose, and Arginine Salts on Monoclonal Antibody Physical Stability and Aggregation During Long-Term Storage.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 584-594
[PDF, 2MB]
Gentiluomo, Lorenzo; Svilenov, Hristo L.; Augustijn, Dillen; El Bialy, Inas; Greco, Maria Laura; Kulakova, Alina; Indrakumar, Sowmya; Mahapatra, Sujata; Morales, Marcello Martinez; Pohl, Christin; Roche, Aisling; Tosstorff, Andreas; Curtis, Robin; Derrick, Jeremy P.; Norgaard, Allan; Khan, Tarik A.; Peters, Gunther H. J.; Pluen, Alain; Rinnan, Asmund; Streicher, Werner W.; Walle, Christopher F. van der; Uddin, Shahid; Winter, Gerhard; Roessner, Dierk; Harris, Pernille und Friess, Wolfgang
(2020):
Advancing Therapeutic Protein Discovery and Development through Comprehensive Computational and Biophysical Characterization.
In: Molecular Pharmaceutics, Bd. 17, Nr. 2: S. 426-440
Gentiluomo, Lorenzo; Roessner, Dierk; Streicher, Werner; Mahapatra, Sujata; Harris, Pernille und Friess, Wolfgang
(2020):
Characterization of Native Reversible Self-Association of a Monoclonal Antibody Mediated by Fab-Fab Interaction.
In: Journal of Pharmaceutical Sciences, Bd. 109, Nr. 1: S. 443-451
Kulakova, Alina; Indrakumar, Sowmya; Sonderby, Pernille; Gentiluomo, Lorenzo; Streicher, Werner; Roessner, Dierk; Friess, Wolfgang; Peters, Guenther H. J. und Harris, Pernille
(2020):
Small angle X-ray scattering and molecular dynamic simulations provide molecular insight for stability of recombinant human transferrin.
In: Journal of Structural Biology-X, Bd. 4, 100017
Pohl, Christin; Zalar, Matja; El Bialy, Inas; Indrakumar, Sowmya; Peters, Gunther H. J.; Friess, Wolfgang; Golovanov, Alexander P.; Streicher, Werner W.; Noergaard, Allan und Harris, Pernille
(2020):
The Effect of Point Mutations on the Biophysical Properties of an Antimicrobial Peptide: Development of a Screening Protocol for Peptide Stability Screening.
In: Molecular Pharmaceutics, Bd. 17, Nr. 9: S. 3298-3313
Tosstorff, Andreas ORCID: https://orcid.org/0000-0002-4969-3667; Svilenov, Hristo ORCID: https://orcid.org/0000-0001-5863-9569; Peters, Günther H. J.; Harris, Pernille und Winter, Gerhard ORCID: https://orcid.org/0000-0002-7413-6627
(12. September 2019):
Structure-based Discovery of a new Protein-Aggregation Breaking Excipient.
In: European Journal of Pharmaceutics and Biopharmaceutics
[HTML, 1MB]
ORCID: https://orcid.org/0000-0002-4969-3667; Svilenov, Hristo ORCID: https://orcid.org/0000-0001-5863-9569; Peters, Günther H. J.; Harris, Pernille und Winter, Gerhard ORCID: https://orcid.org/0000-0002-7413-6627
(12. September 2019):
Structure-based Discovery of a new Protein-Aggregation Breaking Excipient.
In: European Journal of Pharmaceutics and Biopharmaceutics
[HTML, 1MB]
Gentiluomo, Lorenzo; Roessner, Dierk; Augustijn, Dillen; Svilenov, Hristo ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Mahapatra, Sujata; Winter, Gerhard; Streicher, Werner; Rinnan, Asmund; Peters, Günther; Harris, Pernille und Friess, Wolfgang
(August 2019):
Application of interpretable artificial neural networks to early monoclonal antibodies development.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 141: S. 81-89
[PDF, 1MB]
ORCID: https://orcid.org/0000-0001-5863-9569; Kulakova, Alina; Mahapatra, Sujata; Winter, Gerhard; Streicher, Werner; Rinnan, Asmund; Peters, Günther; Harris, Pernille und Friess, Wolfgang
(August 2019):
Application of interpretable artificial neural networks to early monoclonal antibodies development.
In: European Journal of Pharmaceutics and Biopharmaceutics, Bd. 141: S. 81-89
[PDF, 1MB]