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Anzahl der Publikationen: 24
Zeitschriftenartikel
Krainer, Georg 
ORCID: https://orcid.org/0000-0002-9626-7636; Jacquat, Raphael P. B. ORCID: https://orcid.org/0000-0002-8661-9722; Schneider, Matthias M. ORCID: https://orcid.org/0000-0002-1894-1859; Welsh, Timothy J.; Fan, Jieyuan; Peter, Quentin A. E.; Andrzejewska, Ewa A. ORCID: https://orcid.org/0000-0002-1421-5569; Šneiderienė, Greta ORCID: https://orcid.org/0000-0002-4585-5091; Czekalska, Magdalena A. ORCID: https://orcid.org/0000-0002-4494-4463; Ausserwoeger, Hannes ORCID: https://orcid.org/0000-0003-0762-8872; Chai, Lin; Arter, William E.; Saar, Kadi L. ORCID: https://orcid.org/0000-0002-5926-3628; Herling, Therese W. ORCID: https://orcid.org/0000-0002-1332-3090; Franzmann, Titus M. ORCID: https://orcid.org/0000-0002-4281-7209; Kosmoliaptsis, Vasilis ORCID: https://orcid.org/0000-0001-7298-1387; Alberti, Simon ORCID: https://orcid.org/0000-0003-4017-6505; Hartl, F. Ulrich ORCID: https://orcid.org/0000-0002-7941-135X; Lee, Steven F. ORCID: https://orcid.org/0000-0003-4492-5139 und Knowles, Tuomas P. J. ORCID: https://orcid.org/0000-0002-7879-0140
(2024):
Single-molecule digital sizing of proteins in solution.
In: Nature Communications, Bd. 15, 7740
[PDF, 28MB]
ORCID: https://orcid.org/0000-0002-9626-7636; Jacquat, Raphael P. B. ORCID: https://orcid.org/0000-0002-8661-9722; Schneider, Matthias M. ORCID: https://orcid.org/0000-0002-1894-1859; Welsh, Timothy J.; Fan, Jieyuan; Peter, Quentin A. E.; Andrzejewska, Ewa A. ORCID: https://orcid.org/0000-0002-1421-5569; Šneiderienė, Greta ORCID: https://orcid.org/0000-0002-4585-5091; Czekalska, Magdalena A. ORCID: https://orcid.org/0000-0002-4494-4463; Ausserwoeger, Hannes ORCID: https://orcid.org/0000-0003-0762-8872; Chai, Lin; Arter, William E.; Saar, Kadi L. ORCID: https://orcid.org/0000-0002-5926-3628; Herling, Therese W. ORCID: https://orcid.org/0000-0002-1332-3090; Franzmann, Titus M. ORCID: https://orcid.org/0000-0002-4281-7209; Kosmoliaptsis, Vasilis ORCID: https://orcid.org/0000-0001-7298-1387; Alberti, Simon ORCID: https://orcid.org/0000-0003-4017-6505; Hartl, F. Ulrich ORCID: https://orcid.org/0000-0002-7941-135X; Lee, Steven F. ORCID: https://orcid.org/0000-0003-4492-5139 und Knowles, Tuomas P. J. ORCID: https://orcid.org/0000-0002-7879-0140
(2024):
Single-molecule digital sizing of proteins in solution.
In: Nature Communications, Bd. 15, 7740
[PDF, 28MB]
Cairo, Lucas V.; Hong, Xiaoyu; Müller, Martin B.D.; Yuste-Checa, Patricia; Jagadeesan, Chandhuru; Bracher, Andreas; Park, Sae-Hun; Hayer-Hartl, Manajit und Hartl, F. Ulrich
(2024):
Stress-dependent condensate formation regulated by the ubiquitin-related modifier Urm1.
In: Cell, Bd. 187, Nr. 17, e28: S. 4656-4673
[PDF, 12MB]
Hipp, Mark S. ORCID: https://orcid.org/0000-0002-0497-3016 und Hartl, F. Ulrich
(2024):
Interplay of Proteostasis Capacity and Protein Aggregation: Implications for Cellular Function and Disease.
In: Journal of Molecular Biology, 168615 [Forthcoming]
[PDF, 937kB]
ORCID: https://orcid.org/0000-0002-0497-3016 und Hartl, F. Ulrich
(2024):
Interplay of Proteostasis Capacity and Protein Aggregation: Implications for Cellular Function and Disease.
In: Journal of Molecular Biology, 168615 [Forthcoming]
[PDF, 937kB]
Muller, Martin B. D.; Kasturi, Prasad; Jayaraj, Gopal G. und Hartl, F. Ulrich
(2023):
Mechanisms of readthrough mitigation reveal principles of GCN1-mediated translational quality control.
In: Cell, Bd. 186, Nr. 15:
3227-+
[PDF, 14MB]
Furthmann, Nikolas; Bader, Verian; Angersbach, Lena; Blusch, Alina; Goel, Simran; Sanchez-Vicente, Ana; Krause, Laura J.; Chaban, Sarah A.; Grover, Prerna; Trinkaus, Victoria A.; van Well, Eva M.; Jaugstetter, Maximilian; Tschulik, Kristina; Damgaard, Rune Busk; Saft, Carsten; Ellrichmann, Gisa; Gold, Ralf; Koch, Arend; Englert, Benjamin; Westenberger, Ana; Klein, Christine; Jungbluth, Lisa; Sachse, Carsten; Behrends, Christian; Glatzel, Markus; Hartl, F. Ulrich; Nakamura, Ken; Christine, Chadwick W.; Huang, Eric J.; Tatzelt, Jorg und Winklhofer, Konstanze F.
(2023):
NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
In: Nature Communications, Bd. 14, Nr. 1, 8368
[PDF, 23MB]
Saha, Itika; Yuste-Checa, Patricia; Padilha, Miguel Da Silva; Guo, Qiang; Koerner, Roman; Holthusen, Hauke; Trinkaus, Victoria A.; Dudanova, Irina; Fernandez-Busnadiego, Ruben; Baumeister, Wolfgang; Sanders, David W.; Gautam, Saurabh; Diamond, Marc I.; Hartl, F. Ulrich und Hipp, Mark S.
(2023):
The AAA plus chaperone VCP disaggregates Tau fibrils and generates aggregate seeds in a cellular system.
In: Nature Communications, Bd. 14, Nr. 1, 560
[PDF, 6MB]
Yuste-Checa, Patricia; Bracher, Andreas und Hartl, F. Ulrich
(2022):
The chaperone Clusterin in neurodegeneration-friend or foe?
In: Bioessays, Bd. 44, Nr. 7, e2100287
[PDF, 1MB]
Gropp, Michael H. M.; Klaips, Courtney L. und Hartl, F. Ulrich
(2022):
Formation of toxic oligomers of polyQ-expanded Huntingtin by prion-mediated cross-seeding.
In: Molecular Cell, Bd. 82, Nr. 22:
4290-+
[PDF, 3MB]
Riemenschneider, Henrick; Guo, Qiang; Bader, Jakob; Frottin, Frederic; Farny, Daniel; Kleinberger, Gernot; Haass, Christian; Mann, Matthias; Hartl, F. Ulrich; Baumeister, Wolfgang; Hipp, Mark S.; Meissner, Felix; Fernandez-Busnadiego, Ruben und Edbauer, Dieter
(2022):
Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
In: EMBO Reports, Bd. 23, Nr. 6, e53890
[PDF, 1MB]
Yuste-Checa, Patricia; Trinkaus, Victoria A.; Riera-Tur, Irene; Imamoglu, Rahmi; Schaller, Theresa F.; Wang, Huping; Dudanova, Irina; Hipp, Mark S.; Bracher, Andreas und Hartl, F. Ulrich
(2021):
The extracellular chaperone Clusterin enhances Tau aggregate seeding in a cellular model.
In: Nature Communications, Bd. 12, Nr. 1, 4863
[PDF, 2MB]
Trinkaus, Victoria A.; Riera-Tur, Irene; Martinez-Sanchez, Antonio; Bauerlein, Felix J. B.; Guo, Qiang; Arzberger, Thomas; Baumeister, Wolfgang; Dudanova, Irina; Hipp, Mark S.; Hartl, F. Ulrich und Fernandez-Busnadiego, Ruben
(2021):
In situ architecture of neuronal alpha-Synuclein inclusions.
In: Nature Communications, Bd. 12, Nr. 1, 2110
[PDF, 8MB]
Schneider, Matthias M.; Gautam, Saurabh; Herling, Therese W.; Andrzejewska, Ewa; Krainer, Georg; Miller, Alyssa M.; Trinkaus, Victoria A.; Peter, Quentin A. E.; Ruggeri, Francesco Simone; Vendruscolo, Michele; Bracher, Andreas; Dobson, Christopher M.; Hartl, F. Ulrich und Knowles, Tuomas P. J.
(2021):
The Hsc70 disaggregation machinery removes monomer units directly from α-synuclein fibril ends.
In: Nature Communications, Bd. 12, Nr. 1, 5999
[PDF, 3MB]
Klaips, Courtney L.; Gropp, Michael H. M.; Hipp, Mark S. und Hartl, F. Ulrich
(2020):
Sis1 potentiates the stress response to protein aggregation and elevated temperature.
In: Nature Communications, Bd. 11, Nr. 1, 6271
[PDF, 1MB]
Khosravi, Bahram; LaClair, Kathrine D.; Riemenschneider, Henrick; Zhou, Qihui; Frottin, Frederic; Mareljic, Nikola; Czuppa, Mareike; Farny, Daniel; Hartmann, Hannelore; Michaelsen, Meike; Arzberger, Thomas; Hartl, F. Ulrich; Hipp, Mark S. und Edbauer, Dieter
(2020):
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
In: EMBO Journal, Bd. 39, Nr. 8, e102811
[PDF, 2MB]
Hipp, Mark S.; Kasturi, Prasad und Hartl, F. Ulrich
(2019):
The proteostasis network and its decline in ageing.
In: Nature Reviews Molecular Cell Biology, Bd. 20, Nr. 7: S. 421-435
Well, Eva M. van; Bader, Verian; Patra, Maria; Sanchez-Vicente, Ana; Meschede, Jens; Furthmann, Nikolas; Schnack, Cathrin; Blusch, Alina; Longworth, Joseph; Petrasch-Parwez, Elisabeth; Mori, Kohji; Arzberger, Thomas; Truembach, Dietrich; Angersbach, Lena; Showkat, Cathrin; Sehr, Dominik A.; Berlemann, Lena A.; Goldmann, Petra; Clement, Albrecht M.; Behl, Christian; Woerner, Andreas C.; Saft, Carsten; Wurst, Wolfgang; Haass, Christian; Ellrichmann, Gisa; Gold, Ralf; Dittmar, Gunnar; Hipp, Mark S.; Hartl, F. Ulrich; Tatzelt, Jörg und Winklhofer, Konstanze F.
(2019):
A protein quality control pathway regulated by linear ubiquitination.
In: EMBO Journal, Bd. 38, Nr. 9, e100730
[PDF, 2MB]
Su, Ting; Izawa, Toshiaki; Thoms, Matthias; Yamashita, Yui; Cheng, Jingdong; Berninghausen, Otto; Hartl, F. Ulrich; Inada, Toshifumi; Neupert, Walter und Beckmann, Roland
(2019):
Structure and function of Vms1 and Arb1 in RQC and mitochondrial proteome homeostasis.
In: Nature, Bd. 570, Nr. 7762
Vincenz-Donnelly, Lisa; Holthusen, Hauke; Koerner, Roman; Hansen, Erik C.; Presto, Jenny; Johansson, Jan; Sawarkar, Ritwick; Hartl, F. Ulrich und Hipp, Mark S.
(2018):
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.
In: EMBO Journal, Bd. 37, Nr. 3: S. 337-350
Gruber, Anselm; Hornburg, Daniel; Antonin, Matthias; Krahmer, Natalie; Collado, Javier; Schaffer, Miroslava; Zubaite, Greta; Luechtenborg, Christian; Sachsenheimer, Timo; Bruegger, Britta; Mann, Matthias; Baumeister, Wolfgang; Hartl, F. Ulrich; Hipp, Mark S. und Fernandez-Busnadiego, Ruben
(2018):
Molecular and structural architecture of polyQ aggregates in yeast.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 115, Nr. 15, E3446-E3453
Guo, Qiang; Lehmer, Carina; Martinez-Sanchez, Antonio; Rudack, Till; Beck, Florian; Hartmann, Hannelore; Perez-Berlanga, Manuela; Frottin, Frederic; Hipp, Mark S.; Hartl, F. Ulrich; Edbauer, Dieter; Baumeister, Wolfgang und Fernandez-Busnadiego, Ruben
(2018):
In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
In: Cell, Bd. 172, Nr. 4: S. 696-705
Bhat, Javaid Y.; Milicic, Goran; Thieulin-Pardo, Gabriel; Bracher, Andreas; Maxwell, Andrew; Ciniawsky, Susanne; Müller-Cajar, Oliver; Engen, John R.; Hartl, F. Ulrich; Wendler, Petra und Hayer-Hartl, Manajit
(2017):
Mechanism of Enzyme Repair by the AAA(+) Chaperone Rubisco Activase.
In: Molecular Cell, Bd. 67, Nr. 5: S. 744-756
Izawa, Toshiaki; Park, Sae-Hun; Zhao, Liang; Hartl, F. Ulrich und Neupert, Walter
(2017):
Cytosolic Protein Vms1 Links Ribosome Quality Control to Mitochondrial and Cellular Homeostasis.
In: Cell, Bd. 171, Nr. 4: S. 890-903
Woerner, Andreas C.; Frottin, Frédéric; Hornburg, Daniel; Feng, Li R.; Meissner, Felix; Patra, Maria; Tatzelt, Jörg; Mann, Matthias; Winklhofer, Konstanze F.; Hartl, F. Ulrich und Hipp, Mark S.
(2016):
Cytoplasmic protein aggregates interfere with nucleocytoplasmic transport of protein and RNA.
In: Science, Bd. 351, Nr. 6269: S. 173-176
Kim, Yujin E.; Hosp, Fabian; Frottin, Frédéric; Ge, Hui; Mann, Matthias; Hayer-Hartl, Manajit und Hartl, F. Ulrich
(2016):
Soluble Oligomers of PolyQ-Expanded Huntingtin Target a Multiplicity of Key Cellular Factors.
In: Molecular Cell, Bd. 63, Nr. 6: S. 951-964