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Anzahl der Publikationen: 15
Zeitschriftenartikel
Lesch, Stefanie; Nottebrock, Alessia; Rataj, Felicitas; Heise, Constanze; Endres, Stefan und Kobold, Sebastian
(2022):
PD-1-CD28 fusion protein strengthens mesothelin-specific TRuC T cells in preclinical solid tumor models.
In: Cellular Oncology, Bd. 46, Nr. 1: S. 227-235
[PDF, 1MB]
Gao, Li 
ORCID: https://orcid.org/0000-0003-3963-4847; Meiring, Joyce C. M. ORCID: https://orcid.org/0000-0001-9166-5363; Heise, Constanze; Rai, Ankit; Müller‐Deku, Adrian ORCID: https://orcid.org/0000-0001-6050-2545; Akhmanova, Anna ORCID: https://orcid.org/0000-0002-9048-8614; Thorn‐Seshold, Julia ORCID: https://orcid.org/0000-0002-4879-4159 und Thorn‐Seshold, Oliver ORCID: https://orcid.org/0000-0003-3981-651X
(2022):
Photoswitchable Epothilone‐Based Microtubule Stabilisers Allow GFP‐Imaging‐Compatible, Optical Control over the Microtubule Cytoskeleton**.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 10
[PDF, 7MB]
ORCID: https://orcid.org/0000-0003-3963-4847; Meiring, Joyce C. M. ORCID: https://orcid.org/0000-0001-9166-5363; Heise, Constanze; Rai, Ankit; Müller‐Deku, Adrian ORCID: https://orcid.org/0000-0001-6050-2545; Akhmanova, Anna ORCID: https://orcid.org/0000-0002-9048-8614; Thorn‐Seshold, Julia ORCID: https://orcid.org/0000-0002-4879-4159 und Thorn‐Seshold, Oliver ORCID: https://orcid.org/0000-0003-3981-651X
(2022):
Photoswitchable Epothilone‐Based Microtubule Stabilisers Allow GFP‐Imaging‐Compatible, Optical Control over the Microtubule Cytoskeleton**.
In: Angewandte Chemie International Edition, Bd. 61, Nr. 10
[PDF, 7MB]
Rushworth, James L.; Thawani, Aditya R.; Fajardo-Ruiz, Elena; Meiring, Joyce C. M.; Heise, Constanze; White, Andrew J. P.; Akhmanova, Anna; Brandt, Jochen R.; Thorn-Seshold, Oliver und Fuchter, Matthew J.
(2022):
[5]-Helistatins: Tubulin-Binding Helicenes with Antimitotic Activity.
In: JACS Au, Bd. 2, Nr. 11: S. 2561-2570
Gao, Li; Meiring, Joyce C. M.; Varady, Adam; Ruider, Iris E.; Heise, Constanze; Wranik, Maximilian; Velasco, Cecilia D.; Taylor, Jennifer A.; Terni, Beatrice; Weinert, Tobias; Standfuss, Jörg; Cabernard, Clemens C.; Llobet, Artur; Steinmetz, Michel O.; Bausch, Andreas R.; Distel, Martin; Thorn-Seshold, Julia; Akhmanova, Anna und Thorn-Seshold, Oliver
(2022):
In Vivo Photocontrol of Microtubule Dynamics and Integrity, Migration and Mitosis, by the Potent GFP-Imaging-Compatible Photoswitchable Reagents SBTubA4P and SBTub2M.
In: Journal of the American Chemical Society, Bd. 144, Nr. 12: S. 5614-5628
Gao, Li; Kraus, Yvonne; Stegner, Andrea; Wein, Thomas; Heise, Constanze; Brunn, Leonie von; Fajardo-Ruiz, Elena; Thorn-Seshold, Julia und Thorn-Seshold, Oliver
(2022):
Self-reporting styrylthiazolium photopharmaceuticals: mitochondrial localisation as well as SAR drive biological activity.
In: Organic & Biomolecular Chemistry, Bd. 20, Nr. 39: S. 7787-7794
Cadilha, Bruno L.; Benmebarek, Mohamed-Reda; Dorman, Klara; Oner, Arman; Lorenzini, Theo; Obeck, Hannah; Vaenttinen, Mira; Di Pilato, Mauro; Pruessmann, Jasper N.; Stoiber, Stefan; Duc, Huynh; Maerkl, Florian; Seifert, Matthias; Manske, Katrin; Suarez-Gosalvez, Javier; Zeng, Yi; Lesch, Stefanie; Karches, Clara H.; Heise, Constanze; Gottschlich, Adrian; Thomas, Moritz; Marr, Carsten; Zhang, Jin; Pandey, Dharmendra; Feuchtinger, Tobias; Subklewe, Marion; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
Combined tumor-directed recruitment and protection from immune suppression enable CAR T cell efficacy in solid tumors.
In: Science Advances, Bd. 7, Nr. 24, eabi5781
Lesch, Stefanie; Blumenberg, Viktoria; Stoiber, Stefan; Gottschlich, Adrian; Ogonek, Justyna; Cadilha, Bruno L.; Dantes, Zahra; Rataj, Felicitas; Dorman, Klara; Lutz, Johannes; Karches, Clara H.; Heise, Constanze; Kurzay, Mathias; Larimer, Benjamin M.; Grassmann, Simon; Rapp, Moritz; Nottebrock, Alessia; Kruger, Stephan; Tokarew, Nicholas; Metzger, Philipp; Hoerth, Christine; Benmebarek, Mohamed-Reda; Dhoqina, Dario; Grunmeier, Ruth; Seifert, Matthias; Oener, Arman; Umut, Oyku; Joaquina, Sandy; Vimeux, Lene; Tran, Thi; Hank, Thomas; Baba, Taisuke; Huynh, Duc; Megens, Remco T. A.; Janssen, Klaus-Peter; Jastroch, Martin; Lamp, Daniel; Ruehland, Svenja; Di Pilato, Mauro; Pruessmann, Jasper N.; Thomas, Moritz; Marr, Carsten; Ormanns, Steffen; Reischer, Anna; Hristov, Michael; Tartour, Eric; Donnadieu, Emmanuel; Rothenfusser, Simon; Duewell, Peter; Konig, Lars M.; Schnurr, Max; Subklewe, Marion; Liss, Andrew S.; Halama, Niels; Reichert, Maximilian; Mempel, Thorsten R.; Endres, Stefan und Kobold, Sebastian
(2021):
T cells armed with C-X-C chemokine receptor type 6 enhance adoptive cell therapy for pancreatic tumours.
In: Nature Biomedical Engineering, Bd. 5, Nr. 11
Sailer, Alexander; Meiring, Joyce C. M.; Heise, Constanze; Pettersson, Linda N.; Akhmanova, Anna; Thorn-Seshold, Julia und Thorn-Seshold, Oliver
(2021):
Pyrrole Hemithioindigo Antimitotics with Near-Quantitative Bidirectional Photoswitching that Photocontrol Cellular Microtubule Dynamics with Single-Cell Precision**.
In: Angewandte Chemie-International Edition, Bd. 60, Nr. 44: S. 23695-23704
Müller-Deku, Adrian; Meiring, Joyce C. M.; Loy, Kristina; Kraus, Yvonne; Heise, Constanze; Bingham, Rebekkah; Jansen, Klara I.; Qu, Xiaoyi; Bartolini, Francesca; Kapitein, Lukas C.; Akhmanova, Anna; Ahlfeld, Julia; Trauner, Dirk und Thorn-Seshold, Oliver
(2020):
Photoswitchable paclitaxel-based microtubule stabilisers allow optical control over the microtubule cytoskeleton.
In: Nature communications, Bd. 11, Nr. 1, 4640
[PDF, 7MB]
Kraus, Yvonne; Glas, Carina; Melzer, Benedikt; Gao, Li; Heise, Constanze; Preusse, Monique; Ahlfeld, Julia; Bracher, Franz und Thorn-Seshold, Oliver
(2020):
Isoquinoline-based biaryls as a robust scaffold for microtubule inhibitors.
In: European Journal of Medicinal Chemistry, Bd. 186, 111865
Karches, Clara H.; Benmebarek, Mohamed-Reda; Schmidbauer, Moritz L.; Kurzay, Mathias; Klaus, Richard; Geiger, Martina; Rataj, Felicitas; Cadilha, Bruno L.; Lesch, Stefanie; Heise, Constanze; Murr, Ramona; vom Berg, Johannes; Jastroch, Martin; Lamp, Daniel; Ding, Jian; Duewell, Peter; Niederfellner, Gerhard; Sustmann, Claudio; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
Bispecific Antibodies Enable Synthetic Agonistic Receptor-Transduced T Cells for Tumor Immunotherapy.
In: Clinical Cancer Research, Bd. 25, Nr. 19: S. 5890-5900
Wiedemann, Gabriela M.; Aithal, Celina; Kraechan, Angelina; Heise, Constanze; Cadilha, Bruno L.; Zhang, Jin; Duewell, Peter; Ballotti, Robert; Endres, Stefan; Bertolotto, Corine und Kobold, Sebastian
(2019):
Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma.
In: Translational Oncology, Bd. 12, Nr. 2: S. 350-360
Rataj, Felicitas; Jacobi, Severin J.; Stoiber, Stefan; Asang, Florian; Ogonek, Justyna; Tokarew, Nicholas; Cadilha, Bruno L.; van Puijenbroek, Erwin; Heise, Constanze; Duewell, Peter; Endres, Stefan; Klein, Christian und Kobold, Sebastian
(2019):
High-affinity CD16-polymorphism and Fc-engineered antibodies enable activity of CD16-chimeric antigen receptor-modified T cells for cancer therapy.
In: British Journal of Cancer, Bd. 120, Nr. 1: S. 79-87
Rataj, Felicitas; Kraus, Fabian B. T.; Chaloupka, Michael; Grassmann, Simon; Heise, Constanze; Cadilha, Bruno L.; Duewell, Peter; Endres, Stefan und Kobold, Sebastian
(2018):
PD1-CD28 Fusion Protein Enables CD4+ T Cell Help for Adoptive T Cell Therapy in Models of Pancreatic Cancer and Non-hodgkin Lymphoma.
In: Frontiers in Immunology, Bd. 9, 1955
[PDF, 600kB]
Voigt, Cornelia; May, Peter; Gottschlich, Adrian; Markota, Anamarija; Wenk, Daniel; Gerlach, Inga; Voigt, Sebastian; Stathopoulos, Georgios T.; Arendt, Kristina A. M.; Heise, Constanze; Rataj, Felicitas; Janssen, Klaus-Peter; Königshoff, Melanie; Winter, Hauke; Himsl, Isabelle; Thasler, Wolfgang E.; Schnurr, Max; Rothenfußer, Simon; Endres, Stefan und Kobold, Sebastian
(2017):
Cancer cells induce interleukin-22 production from memory CD4(+) T cells via interleukin-1 to promote tumor growth.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 49: S. 12994-12999