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Anzahl der Publikationen: 9
Zeitschriftenartikel
Kaiser, Jesko; Gertzen, Christoph G. W.; Bernauer, Tamara; Hoefner, Georg; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Wanner, Klaus T.; Worek, Franz; Thiermann, Horst und Gohlke, Holger
(2022):
A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment.
In: Toxicology Letters, Bd. 373: S. 160-171
Pasieka, Anna; Panek, Dawid; Jonczyk, Jakub; Godyn, Justyna; Szalaj, Natalia; Latacz, Gniewomir; Tabor, Julia; Mezeiova, Eva; Chantegreil, Fabien; Dias, Jose; Knez, Damijan; Lu, Junfeng; Pi, Rongbiao; Korabecny, Jan; Brazzolotto, Xavier; Gobec, Stanislav; Hoefner, Georg; Wanner, Klaus; Wieckowska, Anna und Malawska, Barbara
(2021):
Discovery of multifunctional anti-Alzheimer's agents with a unique mechanism of action including inhibition of the enzyme butyrylcholinesterase and gamma-aminobutyric acid transporters.
In: European Journal of Medicinal Chemistry, Bd. 218, 113397
Gabriel, Jürgen; Hoefner, Georg und Wanner, Klaus T.
(4. Oktober 2019):
A Library Screening Strategy Combining the Concepts of MS Binding Assays and Affinity Selection Mass Spectrometry.
In: Frontiers in Chemistry, Bd. 7, 665: S. 1-18
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Ackermann, Thomas M.; Bhokare, Karuna; Hoefner, Georg und Wanner, Klaus T.
(2019):
MS binding assays for GlyT1 based on Org24598 as nonlabelled reporter ligand.
In: Neuropharmacology, Bd. 161, 107561
Huber, Simone K.; Hoefner, Georg und Wanner, Klaus T.
(2019):
Application of the concept of oxime library screening by mass spectrometry (MS) binding assays to pyrrolidine-3-carboxylic acid derivatives as potential inhibitors of gamma-aminobutyric acid transporter 1 (GAT1).
In: Bioorganic & Medicinal Chemistry, Bd. 27, Nr. 13: S. 2753-2763
Schaarschmidt, Maren; Hoefner, Georg und Wanner, Klaus T.
(2019):
Synthesis and Biological Evaluation of Nipecotic Acid and Guvacine Derived 1,3-Disubstituted Allenes as Inhibitors of Murine GABA Transporter mGAT1.
In: Chemmedchem, Bd. 14, Nr. 12: S. 1135-1151
Hauke, Tobias J.; Hoefner, Georg und Wanner, Klaus T.
(2019):
MS-Based Screening of 5-Substituted Nipecotic Acid Derived Hydrazone Libraries as Ligands of the GABA Transporter 1.
In: Chemmedchem, Bd. 14, Nr. 5: S. 583-593
Toth, Krisztian; Hoefner, Georg und Wanner, Klaus T.
(2019):
Synthesis and biological evaluation of novel N-substituted nipecotic acid derivatives with a cis-alkene spacer as GABA uptake inhibitors.
In: Bioorganic & Medicinal Chemistry, Bd. 27, Nr. 5: S. 822-831
Hauke, Tobias J.; Hoefner, Georg und Wanner, Klaus T.
(2019):
Generation and screening of pseudostatic hydrazone libraries derived from 5-substituted nipecotic acid derivatives at the GABA transporter mGAT4.
In: Bioorganic & Medicinal Chemistry, Bd. 27, Nr. 1: S. 144-152