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Anzahl der Publikationen: 15
Zeitschriftenartikel
Fessler, Evelyn; Krumwiede, Luisa und Jae, Lucas T.
(6. April 2022):
DELE1 tracks perturbed protein import and processing in human mitochondria.
In: Nature Communications, Bd. 13
[PDF, 3MB]
Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. 
ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Bd. 609: S. 590-596
[PDF, 10MB]
ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Bd. 609: S. 590-596
[PDF, 10MB]
Shammas, Mario K.; Huang, Xiaoping; Wu, Beverly P.; Fessler, Evelyn; Song, Insung Y.; Randolph, Nicholas P.; Li, Yan; Bleck, Christopher K. E.; Springer, Danielle A.; Fratter, Carl; Barbosa, Ines A.; Powers, Andrew F.; Quiros, Pedro M.; Lopez-Otin, Carlos; Jae, Lucas T.; Poulton, Joanna und Narendra, Derek P.
(2022):
OMA1 mediates local and global stress responses against protein misfolding in CHCHD10 mitochondrial.
In: Journal of Clinical Investigation, Bd. 132, Nr. 14, e157504
Eckl, Eva-Maria; Ziegemann, Olga; Krumwiede, Luisa; Fessler, Evelyn und Jae, Lucas T.
(2021):
Sensing, signaling and surviving mitochondrial stress.
In: Cellular and Molecular Life Sciences, Bd. 78, Nr. 16: S. 5925-5951
Loregger, Anke; Raaben, Matthijs; Nieuwenhuis, Joppe; Tan, Josephine M. E.; Jae, Lucas T.; Hengel, Lisa G. van den; Hendrix, Sebastian; Berg, Marlene van den; Scheij, Saskia; Song, Ji-Ying; Huijbers, Ivo J.; Kroese, Lona J.; Ottenhoff, Roelof; Weeghel, Michel van; Sluis, Bart van de; Brummelkamp, Thijn und Zelcer, Noam
(2020):
Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.
In: Nature Communications, Bd. 11, Nr. 1, 1128
[PDF, 3MB]
Reinking, Hannah K.; Kang, Hyun-Seo; Götz, Maximilian J.; Li, Hao-Yi; Kieser, Anja; Zhao, Shubo; Acampora, Aleida C.; Weickert, Pedro; Fessler, Evelyn; Jae, Lucas T.; Sattler, Michael und Stingele, Julian
(2020):
DNA Structure-Specific Cleavage of DNA-Protein Crosslinks by the SPRTN Protease.
In: Molecular Cell, Bd. 80, Nr. 1: S. 102-113
Fessler, Evelyn; Eckl, Eva-Maria; Schmitt, Sabine; Mancilla, Igor Alves; Meyer-Bender, Matthias F.; Hanf, Monika; Philippou-Massier, Julia; Krebs, Stefan; Zischka, Hans und Jae, Lucas T.
(2020):
A pathway coordinated by DELE1 relays mitochondrial stress to the cytosol.
In: Nature, Bd. 579, Nr. 7799: S. 433-437
Mezzadra, Riccardo; Bruijn, Marjolein de; Jae, Lucas T.; Gomez-Eerland, Raquel; Duursma, Anja; Scheeren, Ferenc A.; Brummelkamp, Thijn R. und Schumacher, Ton N.
(2019):
SLFN11 can sensitize tumor cells towards IFN-gamma-mediated T cell killing.
In: PLOS One 14(2), e0212053 [PDF, 1MB]
In: PLOS One 14(2), e0212053 [PDF, 1MB]
Heijink, Anne Margriet; Talens, Francien; Jae, Lucas T.; Gijn, Stephanie E. van; Fehrmann, Rudolf S. N.; Brummelkamp, Thijn R. und Vugt, Marcel A. T. M. van
(2019):
BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity.
In: Nature Communications, Bd. 10, 100
[PDF, 2MB]
Jangra, Rohit K.; Herbert, Andrew S.; Li, Rong; Jae, Lucas T.; Kleinfelter, Lara M.; Slough, Megan M.; Barker, Sarah L.; Guardado-Calvo, Pablo; Roman-Sosa, Gleyder; Dieterle, M. Eugenia; Kuehne, Ana I.; Muena, Nicolas A.; Wirchnianski, Ariel S.; Nyakatura, Elisabeth K.; Fels, J. Maximilian; Ng, Melinda; Mittler, Eva; Pan, James; Bharrhan, Sushma; Wec, Anna Z.; Lai, Jonathan R.; Sidhu, Sachdev S.; Tischler, Nicole D.; Rey, Felix A.; Moffat, Jason; Brummelkamp, Thijn R.; Wang, Zhongde; Dye, John M. und Chandran, Kartik
(2018):
Protocadherin-1 is essential for cell entry by New World hantaviruses.
In: Nature, Bd. 563, Nr. 7732: S. 559-563
Maroofian, Reza; Riemersma, Moniek; Jae, Lucas T.; Zhianabed, Narges; Willemsen, Marjolein H.; Wissink-Lindhout, Willemijn M.; Willemsen, Michel A.; Brouwer, Arjan P. M. de; Mehrjardi, Mohammad Yahya Vahidi; Ashrafi, Mahmoud Reza; Kusters, Benno; Kleefstra, Tjitske; Jamshidi, Yalda; Nasseri, Mojila; Pfundt, Rolph; Brummelkamp, Thijn R.; Abbaszadegan, Mohammad Reza; Lefeber, Dirk J. und Bokhoven, Hans van
(2017):
B3GALNT2 mutations associated with non-syndromic autosomal recessive intellectual disability reveal a lack of genotype-phenotype associations in the muscular dystrophy-dystroglycanopathies.
In: Genome Medicine
9:118
[PDF, 1MB]
Raaben, Matthijs; Jae, Lucas T.; Herbert, Andrew S.; Kühne, Ana I.; Stubbs, Sarah H.; Chou, Yi-ying; Blomen, Vincent A.; Kirchhausen, Tomas; Dye, John M.; Brummelkamp, Thijn R. und Whelan, Sean P.
(2017):
NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry.
In: Cell Host & Microbe, Bd. 22, Nr. 5: S. 688-696
Mezzadra, Riccardo; Sun, Chong; Jae, Lucas T.; Gomez-Eerland, Raquel; Vries, Evert de; Wu, Wei; Logtenberg, Meike E. W.; Slagter, Maarten; Rozeman, Elisa A.; Hofland, Ingrid; Broeks, Annegien; Horlings, Hugo M.; Wessels, Lodewyk F. A.; Blank, Christian U.; Xiao, Yanling; Heck, Albert J. R.; Borst, Jannie; Brummelkamp, Thijn R. und Schumacher, Ton N. M.
(2017):
Identification of CMTM6 and CMTM4 as PD-L1 protein regulators.
In: Nature, Bd. 549, Nr. 7670: S. 106-110
Brockmann, Markus; Blomen, Vincent A.; Nieuwenhuis, Joppe; Stickel, Elmer; Raaben, Matthijs; Bleijerveld, Onno B.; Altelaar, A. F. Maarten; Jae, Lucas T. und Brummelkamp, Thijn R.
(2017):
Genetic wiring maps of single-cell protein states reveal an off-switch for GPCR signalling.
In: Nature, Bd. 546, Nr. 7657: S. 307-311
Jae, Lucas T.; Blomen, Vincent A.; Raaben, Matthijs; Majek, Peter; Herbert, Andrew S.; Brockmann, Markus; Nieuwenhuis, Joppe; Carette, Jan E.; Saftig, Paul; Whelan, Sean P.; Dye, John M.; Superti-Furga, Giulio; Colinge, Jacques und Brummelkamp, Thijn R.
(2016):
Ultra-deep genome mutagenesis in haploid human cells.
In: Glycobiology, Bd. 26, Nr. 12: S. 1378