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Anzahl der Publikationen: 31
Zeitschriftenartikel
Blume, Tanja; Deussing, Maximilian; Biechele, Gloria; Peters, Finn; Zott, Benedikt; Schmidt, Claudio; Franzmeier, Nicolai; Wind, Karin; Eckenweber, Florian; Sacher, Christian; Shi, Yuan; Ochs, Katharina; Kleinberger, Gernot; Xiang, Xianyuan; Focke, Carola; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; von Ungern-Sternberg, Barbara; Bartenstein, Peter; Baumann, Karlheinz; Adelsberger, Helmuth; Rominger, Axel; Cumming, Paul; Willem, Michael; Dorostkar, Mario M.; Herms, Jochen und Brendel, Matthias
(30. März 2022):
Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
In: Frontiers in Aging Neuroscience, Bd. 14
[PDF, 7MB]
Riemenschneider, Henrick; Guo, Qiang; Bader, Jakob; Frottin, Frederic; Farny, Daniel; Kleinberger, Gernot; Haass, Christian; Mann, Matthias; Hartl, F. Ulrich; Baumeister, Wolfgang; Hipp, Mark S.; Meissner, Felix; Fernandez-Busnadiego, Ruben und Edbauer, Dieter
(2022):
Gel-like inclusions of C-terminal fragments of TDP-43 sequester stalled proteasomes in neurons.
In: EMBO Reports, Bd. 23, Nr. 6, e53890
[PDF, 1MB]
Reifschneider, Anika; Robinson, Sophie; Lengerich, Bettina van; Gnörich, Johannes; Logan, Todd; Heindl, Steffanie; Vogt, Miriam A.; Weidinger, Endy; Riedl, Lina; Wind, Karin; Zatcepin, Artem; Pesaemaa, Ida; Haberl, Sophie; Nuscher, Brigitte; Kleinberger, Gernot; Klimmt, Julien; Götzl, Julia K.; Liesz, Arthur; Bürger, Katharina; Brendel, Matthias; Levin, Johannes; Diehl-Schmid, Janine; Suh, Jung; Di Paolo, Gilbert; Lewcock, Joseph W.; Monroe, Kathryn M.; Paquet, Dominik; Capell, Anja und Haass, Christian
(2022):
Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency.
In: EMBO Journal, Bd. 41, Nr. 4, e109108
[PDF, 3MB]
Morenas-Rodriguez, Estrella; Li, Yan; Nuscher, Brigitte; Franzmeier, Nicolai; Xiong, Chengjie; Suarez-Calvet, Marc; Fagan, Anne M.; Schultz, Stephanie; Gordon, Brian A.; Benzinger, Tammie L. S.; Hassenstab, Jason; McDade, Eric; Feederle, Regina; Karch, Celeste M.; Schlepckow, Kai; Morris, John C.; Kleinberger, Gernot; Nellgard, Bengt; Voglein, Jonathan; Blennow, Kaj; Zetterberg, Henrik; Ewers, Michael; Jucker, Mathias; Levin, Johannes; Bateman, Randall J. und Haass, Christian
(2022):
Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study.
In: Lancet Neurology, Bd. 21, Nr. 4: S. 329-341
[PDF, 761kB]
Eninger, Timo; Mueller, Stephan A.; Bacioglu, Mehtap; Schweighauser, Manuel; Lambert, Marius; Maia, Luis F.; Neher, Jonas J.; Hornfeck, Sarah M.; Obermueller, Ulrike; Kleinberger, Gernot; Haass, Christian; Kahle, Philipp J.; Staufenbiel, Matthias; Ping, Lingyan; Duong, Duc M.; Levey, Allan I.; Seyfried, Nicholas T.; Lichtenthaler, Stefan F.; Jucker, Mathias und Kaeser, Stephan A.
(2022):
Signatures of glial activity can be detected in the CSF proteome.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 119, Nr. 24, e2119804119
[PDF, 2MB]
Biechele, Gloria; Blume, Tanja; Deussing, Maximilian; Zott, Benedikt; Shi, Yuan; Xiang, Xianyuan; Franzmeier, Nicolai; Kleinberger, Gernot; Peters, Finn; Ochs, Katharina; Focke, Carola; Sacher, Christian; Wind, Karin; Schmidt, Claudio; Lindner, Simon; Gildehaus, Franz-Josef; Eckenweber, Florian; Beyer, Leonie; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Baumann, Karlheinz; Dorostkar, Mario M.; Rominger, Axel; Cumming, Paul; Willem, Michael; Adelsberger, Helmuth; Herms, Jochen und Brendel, Matthias
(2021):
Pre-therapeutic microglia activation and sex determine therapy effects of chronic immunomodulation.
In: Theranostics, Bd. 11, Nr. 18: S. 8964-8976
[PDF, 1MB]
Schlepckow, Kai; Monroe, Kathryn M.; Kleinberger, Gernot; Cantuti‐Castelvetri, Ludovico; Parhizkar, Samira; Xia, Dan; Willem, Michael; Werner, Georg; Pettkus, Nadine; Brunner, Bettina; Sülzen, Alice; Nuscher, Brigitte; Hampel, Heike; Xiang, Xianyuan; Feederle, Regina; Tahirovic, Sabina; Park, Joshua I.; Prorok, Rachel; Mahon, Cathal; Liang, Chun‐Chi; Shi, Ju; Kim, Do Jin; Sabelström, Hanna; Huang, Fen; Paolo, Gilbert di; Simons, Mikael; Lewcock, Joseph W. und Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627
(7. April 2020):
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
, Bd. 12, Nr. 4, e11227
[PDF, 4MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(7. April 2020):
Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region.
, Bd. 12, Nr. 4, e11227
[PDF, 4MB]
Ewers, Michael; Biechele, Gloria; Suárez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
[PDF, 1MB]
Sacher, Christian; Blume, Tanja; Beyer, Leonie; Biechele, Gloria; Sauerbeck, Julia; Eckenweber, Florian; Deussing, Maximilian; Focke, Carola; Parhizkar, Samira; Lindner, Simon; Gildehaus, Franz-Josef; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Tahirovic, Sabina; Kleinberger, Gernot; Willem, Michael; Haass, Christian; Bartenstein, Peter; Cumming, Paul; Rominger, Axel; Herms, Jochen und Brendel, Matthias
(2020):
Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models.
In: Journal of Nuclear Medicine, Bd. 61, Nr. 12
[PDF, 1MB]
Franzmeier, Nicolai; Suarez-Calvet, M.; Frontzkowski, Lukas; Moore, Annah; Hohman, Timothy J.; Morenas-Rodriguez, Estrella; Nuscher, Brigitte; Shaw, Leslie; Trojanowski, John Q.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Kleinberger, Gernot; Haass, Christian und Ewers, Michael
(2020):
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration.
In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 57
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-0654-387X; Kleinberger, Gernot; Haass, Christian und Ewers, Michael
(2020):
Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration.
In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 57
[PDF, 1MB]
Berner, Dennis Kristopher; Wessolowski, Luisa; Armbrust, Fred; Schneppenheim, Janna; Schlepckow, Kai; Koudelka, Tomas; Scharfenberg, Franka; Lucius, Ralph; Tholey, Andreas; Kleinberger, Gernot; Haass, Christian; Arnold, Philipp und Becker-Pauly, Christoph
(2020):
Meprin beta cleaves TREM2 and controls its phagocytic activity on macrophages.
In: FASEB Journal, Bd. 34, Nr. 5: S. 6675-6687
[PDF, 1MB]
Ewers, Michael; Biechele, Gloria; Suarez-Calvet, Marc; Sacher, Christian; Blume, Tanja; Morenas-Rodriguez, Estrella; Deming, Yuetiva; Piccio, Laura; Cruchaga, Carlos; Kleinberger, Gernot; Shaw, Leslie; Trojanowski, John Q.; Herms, Jochen; Dichgans, Martin; Brendel, Matthias; Haass, Christian und Franzmeier, Nicolai
(2020):
Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO Molecular Medicine, Bd. 12, Nr. 9, e12308
Götzl, Julia K.; Brendel, Matthias; Werner, Georg; Parhizkar, Samira; Monasor, Laura Sebastian; Kleinberger, Gernot; Colombo, Alessio‐Vittorio; Deussing, Maximilian; Wagner, Matias; Winkelmann, Juliane; Diehl‐Schmid, Janine; Levin, Johannes; Fellerer, Katrin; Reifschneider, Anika; Bultmann, Sebastian; Bartenstein, Peter; Rominger, Axel; Tahirovic, Sabina; Smith, Scott T.; Madore, Charlotte; Butovsky, Oleg; Capell, Anja und Haass, Christian
(2019):
Opposite microglial activation stages upon loss of PGRN or TREM2 result in reduced cerebral glucose metabolism.
In: Embo Molecular Medicine, Bd. 11, Nr. 6
[PDF, 1MB]
Ewers, Michael; Franzmeier, Nicolai; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Caballero, Miguel Angel Araque; Kleinberger, Gernot; Piccio, Laura; Cruchaga, Carlos; Deming, Yuetiva; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Trojanowski, John Q.; Shaw, Leslie M.; Weiner, Michael W. und Haass, Christian
(2019):
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
In: Science Translational Medicine, Bd. 11, Nr. 507, eaav6221
[PDF, 786kB]
ORCID: https://orcid.org/0000-0002-0654-387X; Trojanowski, John Q.; Shaw, Leslie M.; Weiner, Michael W. und Haass, Christian
(2019):
Increased soluble TREM2 in cerebrospinal fluid is associated with reduced cognitive and clinical decline in Alzheimer's disease.
In: Science Translational Medicine, Bd. 11, Nr. 507, eaav6221
[PDF, 786kB]
Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jörge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura und Cruchaga, Carlos
(2019):
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
In: Science Translational Medicine, Bd. 11, Nr. 505, eaau2291
[PDF, 1MB]
Focke, Carola; Blume, Tanja; Zott, Benedikt; Shi, Yuan; Deussing, Maximilian; Peters, Finn; Schmidt, Claudio; Kleinberger, Gernot; Lindner, Simon; Gildehaus, Franz-Josef; Beyer, Leonie; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Ozmen, Laurence; Baumann, Karlheinz; Dorostkar, Mario M.; Haass, Christian; Adelsberger, Helmuth; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2019):
Early and Longitudinal Microglial Activation but Not Amyloid Accumulation Predicts Cognitive Outcome in PS2APP Mice.
In: Journal of Nuclear Medicine, Bd. 60, Nr. 4: S. 548-554
[PDF, 1MB]
Parhizkar, Samira; Arzberger, Thomas; Brendel, Matthias; Kleinberger, Gernot; Deussing, Maximilian; Focke, Carola; Nuscher, Brigitte; Xiong, Monica; Ghasemigharagoz, Alireza; Katzmarski, Natalie; Krasemann, Susanne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Colombo, Alessio; Monasor, Laura Sebastian; Tahirovic, Sabina; Herms, Jochen; Willem, Michael; Pettkus, Nadine; Butovsky, Oleg; Bartenstein, Peter; Edbauer, Dieter; Rominger, Axel; Ertuerk, Ali; Grathwohl, Stefan A.; Neher, Jonas J.; Holtzman, David M.; Meyer-Luehmann, Melanie und Haass, Christian
(2019):
Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE.
In: Nature Neuroscience, Bd. 22, Nr. 2
[PDF, 6MB]
Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Schlepckow, Kai; Caballero, Miguel Angel Araque; Franzmeier, Nicolai; Capell, Anja; Fellerer, Katrin; Nuscher, Brigitte; Eren, Erden; Levin, Johannes; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian
(2019):
Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology.
In: Molecular Neurodegeneration, Bd. 14, 1
[PDF, 1MB]
Suarez-Calvet, Marc; Capell, Anja; Caballero, Miguel Angel Araque; Morenas-Rodriguez, Estrella; Fellerer, Katrin; Franzmeier, Nicolai; Kleinberger, Gernot; Eren, Erden; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Paumier, Katrina; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Jucker, Mathias; Masters, Colin L.; Rossor, Martin N.; Ringman, John M.; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
In: EMBO Molecular Medicine, Bd. 10, Nr. 12, e9712
Xiang, Xianyuan; Piers, Thomas M.; Wefers, Benedikt; Zhu, Kaichuan; Mallach, Anna; Brunner, Bettina; Kleinberger, Gernot; Song, Wilbur; Colonna, Marco; Herms, Jochen; Wurst, Wolfgang; Pocock, Jennifer M. und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
Brendel, Matthias; Kleinberger, Gernot; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Blume, Tanja; Albert, Nathalie L.; Carlsen, Janette; Lindner, Simon; Gildehaus, Franz Josef; Ozmen, Laurence; Suarez-Calvet, Marc; Bartenstein, Peter; Baumann, Karlheinz; Ewers, Michael; Herms, Jochen; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel
(Januar 2017):
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
In: Frontiers in aging neuroscience, Bd. 9, 8
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4869-1627 und Rominger, Axel
(Januar 2017):
Increase of TREM2 during Aging of an Alzheimer's Disease Mouse Model Is Paralleled by Microglial Activation and Amyloidosis.
In: Frontiers in aging neuroscience, Bd. 9, 8
[PDF, 2MB]
Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
Mazaheri, Fargol; Snaidero, Nicolas; Kleinberger, Gernot; Madore, Charlotte; Daria, Anna; Werner, Georg; Krasemann, Susanne; Capell, Anja; Trümbach, Dietrich; Wurst, Wolfgang; Brunner, Bettina; Bultmann, Sebastian; Tahirovic, Sabina; Kerschensteiner, Martin; Misgeld, Thomas; Butovsky, Oleg und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
TREM2 deficiency impairs chemotaxis and microglial responses to neuronal injury.
In: Embo Reports, Bd. 18, Nr. 7: S. 1186-1198
Brendel, Matthias; Focke, Carola; Blume, Tanja; Peters, Finn; Deussing, Maximilian; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Kleinberger, Gernot; Herms, Jochen und Rominger, Axel
(2017):
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
In: Journal of Nuclear Medicine, Bd. 58, Nr. 12: S. 1984-1990
ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Bartenstein, Peter; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Kleinberger, Gernot; Herms, Jochen und Rominger, Axel
(2017):
Time Courses of Cortical Glucose Metabolism and Microglial Activity Across the Life Span of Wild-Type Mice: A PET Study.
In: Journal of Nuclear Medicine, Bd. 58, Nr. 12: S. 1984-1990
Schlepckow, Kai; Kleinberger, Gernot; Fukumori, Akio; Feederle, Regina; Lichtenthaler, Stefan F.; Steiner, Harald und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
An Alzheimer-associated TREM2 variant occurs at the ADAM cleavage site and affects shedding and phagocytic function.
In: Embo Molecular Medicine, Bd. 9, Nr. 10: S. 1356-1365
[PDF, 1MB]
Brendel, Matthias; Probst, Federico; Jaworska, Anna; Overhoff, Felix; Korzhova, Viktoria; Albert, Nathalie L.; Beck, Roswitha; Lindner, Simon; Gildehaus, Franz-Josef; Baumann, Karlheinz; Bartenstein, Peter; Kleinberger, Gernot; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Herms, Jochen und Rominger, Axel
(2016):
Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study.
In: Journal of Nuclear Medicine, Bd. 57, Nr. 6: S. 954-960
ORCID: https://orcid.org/0000-0002-4869-1627; Herms, Jochen und Rominger, Axel
(2016):
Glial Activation and Glucose Metabolism in a Transgenic Amyloid Mouse Model: A Triple-Tracer PET Study.
In: Journal of Nuclear Medicine, Bd. 57, Nr. 6: S. 954-960
Kleinberger, Gernot; Capell, Anja; Brouwers, Nathalie; Fellerer, Katrin; Sleegers, Kristel; Cruts, Marc; Broeckhoven, Christine van und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin.
In: Neurobiology of Aging, Bd. 39, 220.e17
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced secretion and altered proteolytic processing caused by missense mutations in progranulin.
In: Neurobiology of Aging, Bd. 39, 220.e17
Suárez-Calvet, Marc; Caballero, Miguel Ángel Araque; Kleinberger, Gernot; Bateman, Randall J.; Fagan, Anne M.; Morris, John C.; Levin, Johannes; Danek, Adrian; Ewers, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury.
In: Science Translational Medicine, Bd. 8, Nr. 369, 369ra178
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Early changes in CSF sTREM2 in dominantly inherited Alzheimer's disease occur after amyloid deposition and neuronal injury.
In: Science Translational Medicine, Bd. 8, Nr. 369, 369ra178
Xiang, Xianyuan; Werner, Georg; Bohrmann, Bernd; Liesz, Arthur; Mazaheri, Fargol; Capell, Anja; Feederle, Regina; Knuesel, Irene; Kleinberger, Gernot und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance.
In: Embo Molecular Medicine, Bd. 8, Nr. 9: S. 992-1004
[PDF, 1MB]
Suarez-Calvet, Marc; Kleinberger, Gernot; Araque Caballero, Miguel Angel; Brendel, Matthias; Rominger, Axel; Alcolea, Daniel; Fortea, Juan; Lleo, Alberto; Blesa, Rafael; Gispert, Juan Domingo; Sanchez-Valle, Raquel; Antonell, Anna; Rami, Lorena; Molinuevo, Jose L.; Brosseron, Frederic; Traschutz, Andreas; Heneka, Michael T.; Struyfs, Hanne; Engelborghs, Sebastiaan; Sleegers, Kristel; Broeckhoven, Christine van; Zetterberg, Henrik; Nellgard, Bengt; Blennow, Kaj; Crispin, Alexander; Ewers, Michael und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
In: EMBO Molecular Medicine, Bd. 8, Nr. 5: S. 466-476
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
sTREM2 cerebrospinal fluid levels are a potential biomarker for microglia activity in early-stage Alzheimer's disease and associate with neuronal injury markers.
In: EMBO Molecular Medicine, Bd. 8, Nr. 5: S. 466-476
Janssens, Jonathan; Philtjens, Stephanie; Kleinberger, Gernot; Mossevelde, Sara van; Zee, Julie van der; Cacace, Rita; Engelborghs, Sebastiaan; Sieben, Anne; Banzhaf-Strathmann, Julia; Dillen, Lubina; Merlin, Celine; Cuijt, Ivy; Robberecht, Caroline; Schmid, Bettina; Santens, Patrick; Ivanoiu, Adrian; Vandenbulcke, Mathieu; Vandenberghe, Rik; Cras, Patrick; De Deyn, Peter P.; Martin, Jean-Jacques; Maudsley, Stuart; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Cruts, Marc und Broeckhoven, Christine van
(2015):
Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains.
In: Acta Neuropathologica Communications
3:68
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-4869-1627; Cruts, Marc und Broeckhoven, Christine van
(2015):
Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains.
In: Acta Neuropathologica Communications
3:68
[PDF, 3MB]