Anzahl der Publikationen: 25
2023
Pastore, Friederike ORCID: https://orcid.org/0000-0002-2220-2346; Gittinger, Hanna; Raab, Susanne; Tschuri, Sebastian; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Rothenberg‐Thurley, Maja; Horny, Hans‐Peter; Werner, Martin; Sauerland, Maria C. ORCID: https://orcid.org/0000-0002-8748-8218; Amler, Susanne ORCID: https://orcid.org/0000-0001-6903-2906; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard ORCID: https://orcid.org/0000-0003-2273-5502; Braess, Jan; Hiddemann, Wolfgang; Tischer, Johanna ORCID: https://orcid.org/0000-0003-1821-1976; Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957
(2023):
Acute megakaryoblastic leukaemia shows high frequency of chromosome 1q aberrations and dismal outcome.
In: British Journal of Haematology, Bd. 202, Nr. 6: S. 1165-1177
[PDF, 1MB]
Batcha, Aarif M. N. ORCID: https://orcid.org/0000-0002-7972-7506; Buckup, Nele; Bamopoulos, Stefanos A ORCID: https://orcid.org/0000-0002-5997-7735; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Gittinger, Hanna; Ksienzyk, Bianka; Dufour, Annika; Schneider, Stephanie; Kontro, Mika; Saad, Joseph ORCID: https://orcid.org/0000-0001-7701-0328; Heckman, Caroline A. ORCID: https://orcid.org/0000-0002-4324-8706; Sauerland, Cristina M.; Görlich, Dennis ORCID: https://orcid.org/0000-0002-2574-9419; Berdel, Wolfgang E. ORCID: https://orcid.org/0000-0002-3030-6567; Wörmann, Bernhard; Krug, Utz; Braess, Jan; Mansmann, Ulrich Robert ORCID: https://orcid.org/0000-0002-9955-8906; Hiddemann, Wolfgang; Spiekermann, Karsten ORCID: https://orcid.org/0000-0002-5139-4957; Metzeler, Klaus H. ORCID: https://orcid.org/0000-0003-3920-7490 und Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432
(2023):
Germline SNPs previously implicated as prognostic biomarkers do not associate with outcomes in intensively treated AML.
In: Blood Advances, Bd. 7, Nr. 6: S. 1040-1044
2022
Hartmann, Luise; Hecker, Judith S.; Rothenberg-Thurley, Maja; Riviere, Jennifer; Jentzsch, Madlen; Ksienzyk, Bianka; Buck, Michele C.; Garde, Mark van der; Fischer, Luise; Winter, Susann; Rauner, Martina; Tsourdi, Elena; Weidner, Heike; Sockel, Katja; Schneider, Marie; Kubasch, Anne S.; Nolde, Martin; Hausmann, Dominikus; Luetzner, Joerg; Goralski, Szymon; Bassermann, Florian; Spiekermann, Karsten; Hofbauer, Lorenz C.; Schwind, Sebastian; Platzbecker, Uwe; Goetze, Katharina S. und Metzeler, Klaus H.
(2022):
Compartment-specific mutational landscape of clonal hematopoiesis.
In: Leukemia, Bd. 36, Nr. 11: S. 2647-2655
Pastore, Friederike ORCID: https://orcid.org/0000-0002-2220-2346; Pastore, Alessandro; Rothenberg-Thurley, Maja; Metzeler, Klaus H.; Ksienzyk, Bianka; Schneider, Stephanie; Bohlander, Stefan K.; Braess, Jan; Sauerland, Maria C.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard; Bergwelt-Baildon, Michael von; Hiddemann, Wolfgang und Spiekermann, Karsten
(2022):
Molecular profiling of patients with cytogenetically normal acute myeloid leukemia and hyperleukocytosis.
In: Cancer, Bd. 128, Nr. 24: S. 4213-4222
[PDF, 1MB]
2021
Moser, Christian; Jurinovic, Vindi; Sagebiel-Kohler, Sabine; Ksienzyk, Bianka; Batcha, Aarif M. N.; Dufour, Annika; Schneider, Stephanie; Rothenberg-Thurley, Maja; Sauerland, Cristina M.; Gorlich, Dennis; Berdel, Wolfgang E.; Krug, Utz; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Greif, Philipp A.; Vosberg, Sebastian; Metzeler, Klaus H.; Kumbrink, Joerg und Herold, Tobias
(2021):
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
In: Blood Advances, Bd. 5, Nr. 22: S. 4752-4761
Hecker, Judith S.; Hartmann, Luise; Riviere, Jennifer; Buck, Michele C.; Garde, Mark van de; Rothenberg-Thurley, Maja; Fischer, Luise; Winter, Susann; Ksienzyk, Bianka; Ziemann, Frank; Solovey, Maria; Rauner, Martina; Tsourdi, Elena; Sockel, Katja; Schneider, Marie; Kubasch, Anne S.; Nolde, Martin; Hausmann, Dominikus; Paulus, Alexander C.; Luetzner, Joerg; Roth, Andreas; Bassermann, Florian; Spiekermann, Karsten; Marr, Carsten; Hofbauer, Lorenz C.; Platzbecker, Uwe; Metzeler, Klaus H. und Goetze, Katharina S.
(2021):
CHIP and hips: clonal hematopoiesis is common in patients undergoing hip arthroplasty and is associated with autoimmune disease.
In: Blood, Bd. 138, Nr. 18: S. 1727-1732
Moser, Christian; Jurinovic, Vindi; Sagebiel-Kohler, Sabine; Ksienzyk, Bianka; Batcha, Aarif M. N.; Dufour, Annika; Schneider, Stephanie; Rothenberg-Thurley, Maja; Sauerland, Cristina M.; Görlich, Dennis und Herold, Tobias
(2021):
A clinically applicable gene expression-based score predicts resistance to induction treatment in acute myeloid leukemia.
In: Blood Advances, Bd. 5, Nr. 22: S. 4752-4761
2020
Stief, Sophie M.; Hanneforth, Anna-Li; Weser, Sabrina; Mattes, Raphael; Carlet, Michela; Liu, Wen-Hsin; Bartoschek, Michael D.; Moreno, Helena Dominguez; Oettle, Matthias; Kempf, Julia; Vick, Binje; Ksienzyk, Bianka; Tizazu, Belay; Rothenberg-Thurley, Maja; Quentmeier, Hilmar; Hiddemann, Wolfgang; Vosberg, Sebastian; Greif, Philipp A.; Metzeler, Klaus H.; Schotta, Gunnar; Bultmann, Sebastian; Jeremias, Irmela; Leonhardt, Heinrich und Spiekermann, Karsten
(2020):
Loss of KDM6A confers drug resistance in acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 1: S. 50-62
Opatz, Sabrina; Bamopoulos, Stefanos A.; Metzeler, Klaus H.; Herold, Tobias; Ksienzyk, Bianka; Braeundl, Kathrin; Tschuri, Sebastian; Vosberg, Sebastian; Konstandin, Nikola P.; Wang, Christine; Hartmann, Luise; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Thiede, Christian; Middeke, Jan Moritz; Stoelzel, Friedrich; Roellig, Christoph; Schetelig, Johannes; Ehninger, Gerhard; Kraemer, Alwin; Braess, Jan; Goerlich, Dennis; Sauerland, Maria Cristina; Berdel, Wolfgang E.; Woermann, Bernhard J.; Hiddemann, Wolfgang; Spiekermann, Karsten; Bohlander, Stefan K. und Greif, Philipp A.
(2020):
The clinical mutatome of core binding factor leukemia.
In: Leukemia, Bd. 34, Nr. 6: S. 1553-1562
Herold, Tobias ORCID: https://orcid.org/0000-0002-9615-9432; Rothenberg-Thurley, Maja; Grunwald, Victoria V.; Janke, Hanna; Goerlich, Dennis; Sauerland, Maria C.; Konstandin, Nikola P.; Dufour, Annika; Schneider, Stephanie; Neusser, Michaela; Ksienzyk, Bianka; Greif, Philipp A.; Subklewe, Marion; Faldum, Andreas; Bohlander, Stefan K.; Braess, Jan; Wörmann, Bernhard; Krug, Utz; Berdel, Wolfgang E.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2020):
Validation and refinement of the revised 2017 European LeukemiaNet genetic risk stratification of acute myeloid leukemia.
In: Leukemia, Bd. 34: S. 3161-3172
[PDF, 2MB]
Bamopoulos, Stefanos A.; Batcha, Aarif M. N.; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Janke, Hanna; Ksienzyk, Bianka; Philippou-Massier, Julia; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Woermann, Bernhard J.; Bohlander, Stefan K.; Canzar, Stefan; Mansmann, Ulrich; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten; Metzeler, Klaus H. und Herold, Tobias
(2020):
Clinical presentation and differential splicing of SRSF2, U2AF1 and SF3B1 mutations in patients with acute myeloid leukemia.
In: Leukemia, Bd. 34, Nr. 10: S. 2621-2634
2019
Batcha, Aarif M. N.; Bamopoulos, Stefanos A.; Kerbs, Paul; Kumar, Ashwini; Jurinovic, Vindi; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Philippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Schneider, Stephanie; Konstandin, Nikola; Bohlander, Stefan K.; Heckman, Caroline; Kontro, Mika; Hiddemann, Wolfgang; Spiekermann, Karsten; Braess, Jan; Metzeler, Klaus H.; Greif, Philipp A.; Mansmann, Ulrich und Herold, Tobias
(2019):
Allelic Imbalance of Recurrently Mutated Genes in Acute Myeloid Leukaemia.
In: Scientific Reports, Bd. 9, Nr. 11796
[PDF, 1MB]
2018
Herold, Tobias; Jurinovic, Vindi; Batcha, Aarif Mohamed Nazeer; Bamopoulos, Stefanos A.; Rothenberg-Thurley, Maja; Ksienzyk, Bianka; Hartmann, Luise; Greif, Philipp A.; Phillippou-Massier, Julia; Krebs, Stefan; Blum, Helmut; Amler, Susanne; Schneider, Stephanie; Konstandin, Nikola P.; Sauerland, Maria Cristina; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Tischer, Johanna; Subklewe, Marion; Bohlander, Stefan K.; Braess, Jan; Hiddemann, Wolfgang; Metzeler, Klaus H.; Mansmann, Ulrich und Spiekermann, Karsten
(März 2018):
A 29-gene and cytogenetic score for the prediction of resistance to induction treatment in acute myeloid leukemia.
In: Haematologica, Bd. 103, Nr. 3: S. 456-65
Rothenberg-Thurley, Maja; Amler, Susanne; Goerlich, Dennis; Köhnke, Thomas; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Herold, Tobias; Hubmann, Max; Ksienzyk, Bianka; Zellmeier, Evelyn; Bohlander, Stefan K.; Subklewe, Marion; Faldum, Andreas; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
In: Leukemia, Bd. 32, Nr. 7: S. 1598-1608
Prassek, Victoria V.; Rothenberg-Thurley, Maja; Sauerland, Maria C.; Herold, Tobias; Janke, Hanna; Ksienzyk, Bianka; Konstandin, Nikola P.; Goerlich, Dennis; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Braess, Jan; Schneider, Stephanie; Subklewe, Marion; Bohlander, Stefan K.; Hiddemann, Wolfgang; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Genetics of acute myeloid leukemia in the elderly: mutation spectrum and clinical impact in intensively treated patients aged 75 years or older.
In: Haematologica, Bd. 103, Nr. 11: S. 1853-1861
[PDF, 1MB]
Konstandin, Nikola P.; Pastore, Friederike; Herold, Tobias; Dufour, Annika; Rothenberg-Thurley, Maja; Hinrichsen, Tanja; Ksienzyk, Bianka; Tschuri, Sebastian; Schneider, Stephanie; Hoster, Eva; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Sauerland, Maria C.; Braess, Jan; Bohlander, Stefan K.; Klein, Hanns-Georg; Hiddemann, Wolfgang; Metzeler, Klaus H. und Spiekermann, Karsten
(2018):
Genetic heterogeneity of cytogenetically normal AML with mutations of CEBPA.
In: Blood Advances, Bd. 2, Nr. 20: S. 2724-2731
Schranz, Katrin; Hubmann, Max; Harin, Egor; Vosberg, Sebastian; Herold, Tobias; Metzeler, Klaus H.; Rothenberg-Thurley, Maja; Janke, Hanna; Bräundl, Kathrin; Ksienzyk, Bianka; Batcha, Aarif M. N.; Schaaf, Sebastian; Schneider, Stephanie; Bohlander, Stefan K.; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Krebs, Stefan; Hiddemann, Wolfgang; Mansmann, Ulrich; Spiekermann, Karsten und Greif, Philipp A.
(2018):
Clonal heterogeneity of FLT3-ITD detected by high-throughput amplicon sequencing correlates with adverse prognosis in acute myeloid leukemia.
In: Oncotarget, Bd. 9, Nr. 53: S. 30128-30145
[PDF, 2MB]
Greif, Philipp A.; Hartmann, Luise; Vosberg, Sebastian; Stief, Sophie M.; Mattes, Raphael; Hellmann, Ines; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Kerbs, Paul; Jurinovic, Vindi; Schumacher, Daniela; Pastore, Friederike; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Neumann, Martin; Baldus, Claudia D.; Bohlander, Stefan K.; Wolf, Stephan; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2018):
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
In: Clinical Cancer Research, Bd. 24, Nr. 7: S. 1716-1726
2017
Herold, Tobias; Metzeler, Klaus H.; Vosberg, Sebastian; Hartmann, Luise; Jurinovic, Vindi; Opatz, Sabrina; Konstandin, Nikola P.; Schneider, S.; Zellmeier, Evelyn; Ksienzyk, Bianka; Graf, A.; Krebs, S.; Blum, H.; Sauerland, Maria Cristina; Büchner, T.; Berdel, W. E.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K.; Spiekermann, Karsten und Greif, Philipp A.
(2017):
Acute Myeloid Leukemia with Del(9q) is Characterized by Frequent Mutations of NPM1, DNMT3A, WT1 and Low Expression of TLE4.
In: Genes, Chromosomes and Cancer, Bd. 56, Nr. 1: S. 75-86
Herold, Tobias; Schneider, S.; Metzeler, Klaus H.; Neumann, Martin; Hartmann, Luise; Roberts, Kathryn G.; Konstandin, Nikola P.; Greif, Philipp A.; Bräundl, Kathrin; Ksienzyk, Bianka; Huk, Natalia; Schneider, Irene; Zellmeier, Evelyn; Jurinovic, Vindi; Mansmann, Ulrich; Hiddemann, Wolfgang; Mullighan, Charles G.; Bohlander, Stefan K.; Spiekermann, Karsten; Hölzel, Dieter; Brüggemann, Monika; Baldus, Claudia D.; Dreyling, Martin und Gökbuget, Nicola
(2017):
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
In: Haematologica, Bd. 102, Nr. 1: S. 130-138
[PDF, 1MB]
2016
Metzeler, Klaus H.; Herold, Tobias; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria C.; Görlich, Dennis; Schneider, Stephanie; Konstandin, Nikola P.; Dufour, Annika; Bräundl, Kathrin; Ksienzyk, Bianka; Zellmeier, Evelyn; Hartmann, Luise; Greif, Philipp A.; Fiegl, Michael; Subklewe, Marion; Bohlander, Stefan K.; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Büchner, Thomas; Hiddemann, Wolfgang; Braess, Jan und Spiekermann, Karsten
(2016):
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
In: Blood, Bd. 128, Nr. 5: S. 686-698
Hartmann, Luise; Dutta, Sayantanee; Opatz, Sabrina; Vosberg, Sebastian; Reiter, Katrin; Leubolt, Georg; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Hopfner, Karl-Peter; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Middeke, Jan Moritz; Stölzel, Friedrich; Thiede, Christian; Wolf, Stephan; Bohlander, Stefan K.; Preiss, Caroline; Chen-Wichmann, Linping; Wichmann, Christian; Sauerland, Maria Cristina; Büchner, Thomas; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten und Greif, Philipp A.
(2016):
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
In: Nature Communications, Bd. 7, 11733
[PDF, 1MB]
2014
Pastore, Friederike; Greif, Philipp A.; Schneider, Stephanie; Ksienzyk, Bianka; Mellert, Gudrun; Zellmeier, Evelyn; Braess, Jan; Sauerland, Cristina M.; Heinecke, Achim; Krug, Utz; Berdel, Wolfgang E.; Buechner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML.
In: PLOS ONE
9(10), e109759
[PDF, 605kB]
2012
Dufour, A.; Schneider, F.; Hoster, Eva; Benthaus, T.; Ksienzyk, Bianka; Schneider, S.; Kakadia, P. M.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Subklewe, M.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2012):
Monoallelic CEBPA mutations in normal karyotype acute myeloid leukemia: independent favorable prognostic factor within NPM1 mutated patients.
In: Annals of Hematology, Bd. 91, Nr. 7: S. 1051-1063
Greif, Philipp A.; Dufour, A.; Konstandin, Nikola P.; Ksienzyk, Bianka; Zellmeier, Evelyn; Tizazu, B.; Sturm, J.; Benthaus, T.; Herold, Tobias; Yaghmaie, M.; Dorge, P.; Hopfner, K. P.; Hauser, A.; Graf, A.; Krebs, S.; Blum, H.; Kakadia, P. M.; Schneider, S.; Hoster, Eva; Schneider, F.; Stanulla, M.; Braess, J.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten und Bohlander, Stefan K.
(2012):
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
In: Blood, Bd. 120, Nr. 2: S. 395-403
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