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Anzahl der Publikationen: 13
Zeitschriftenartikel
Lacy, Michael; Buerger, Christina; Shami, Annelie; Ahmadsei, Maiwand; Winkels, Holger; Nitz, Katrin; Tiel, Claudia M. van; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Karshovka, Ela; Prange, Koen H. M.; Wu, Yuting; Brouns, Sanne L. N.; Unterlugauer, Sigrid; Kuijpers, Marijke J. E.; Reiche, Myrthe E.; Steffens, Sabine; Edsfeldt, Andreas; Megens, Remco T. A.; Heemskerk, Johan W. M.; Goncalves, Isabel; Weber, Christian; Gerdes, Norbert; Atzler, Dorothee und Lutgens, Esther
(2021):
Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease.
In: Nature Communications, Bd. 12, Nr. 1, 3754
Poels, Kikkie; Leent, Mandy M. T. van; Boutros, Celine; Tissot, Hubert; Roy, Severine; Meerwaldt, Anu E.; Toner, Yohana C. A.; Reiche, Myrthe E.; Kusters, Pascal J. H.; Malinova, Tsveta; Huveneers, Stephan; Kaufman, Audrey E.; Mani, Venkatesh; Fayad, Zahi A.; Winther, Menno P. J. de; Marabelle, Aurelien; Mulder, Willem J. M.; Robert, Caroline; Seijkens, Tom T. P. und Lutgens, Esther
(2020):
Immune Checkpoint Inhibitor Therapy Aggravates T Cell-Driven Plaque Inflammation in Atherosclerosis.
In: Jacc: Cardiooncology, Bd. 2, Nr. 4: S. 599-610
Poels, Kikkie; Leent, Mandy M. T. van; Reiche, Myrthe E.; Kusters, Pascal J. H.; Huveneers, Stephan; Winther, Menno P. J. de; Mulder, Willem J. M.; Lutgens, Esther und Seijkens, Tom T. P.
(2020):
Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice.
In: Cells, Bd. 9, Nr. 9, 1987
Bosmans, Laura A.; Bosch, Lena; Kusters, Pascal J. H.; Lutgens, Esther und Seijkens, Tom T. P.
(2020):
The CD40-CD40L Dyad as Immunotherapeutic Target in Cardiovascular Disease.
In: Journal of Cardiovascular Translational Research, Bd. 14, Nr. 1: S. 13-22
Seijkens, Tom T. P.; Poels, Kikkie; Meiler, Svenja; van Tiel, Claudia M.; Kusters, Pascal J. H.; Reiche, Myrthe; Atzler, Dorothee; Winkels, Holger; Tjwa, Marc; Poelman, Hessel; Slutter, Bram; Kuiper, Johan; Gijbels, Marion; Kuivenhoven, Jan Albert; Matic, Ljubica Perisic; Paulsson-Berne, Gabrielle; Hedin, Ulf; Hansson, Goran K.; Nicolaes, Gerry A. F.; Daemen, Mat J. A. P.; Weber, Christian; Gerdes, Norbert; de Winther, Menno P. J. und Lutgens, Esther
(2019):
Deficiency of the T cell regulator Casitas B-cell lymphoma-B aggravates atherosclerosis by inducing CD8(+) T cell-mediated macrophage death.
In: European Heart Journal, Bd. 40, Nr. 4
Aarts, Suzanne A. B. M.; Seijkens, Tom T. P.; Kusters, Pascal J. H.; van Tiel, Claudia M.; Reiche, Myrthe E.; den Toom, Myrthe; Beckers, Linda; van Roomen, Cindy P. A. A.; de Winther, Menno P. J.; Kooij, Gijs und Lutgens, Esther
(2019):
Macrophage CD40 signaling drives experimental autoimmune encephalomyelitis.
In: Journal of Pathology, Bd. 247, Nr. 4: S. 471-480
Kusters, Pascal J. H.; Seijkens, Tom T. P.; Beckers, Linda; Lievens, Dirk; Winkels, Holger; Waard, Vivian de; Duijvestijn, Adriaan; Liljeqvist, Moritz Lindquist; Roy, Joy; Daugherty, Alan; Newby, Andrew; Gerdes, Norbert und Lutgens, Esther
(2018):
CD40L Deficiency Protects Against Aneurysm Formation.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 5: S. 1076-1085
[PDF, 1MB]
Kusters, Pascal J. H.; Lutgens, Esther und Seijkens, Tom T. P.
(2018):
Exploring immune checkpoints as potential therapeutic targets in atherosclerosis.
In: Cardiovascular Research, Bd. 114, Nr. 3: S. 368-377
Seijkens, Tom T. P.; Tiel, Claudia M. van; Kusters, Pascal J. H.; Atzler, Dorothee; Soehnlein, Oliver; Zarzycka, Barbara; Aarts, Suzanne A. B. M.; Lameijer, Marnix; Gijbels, Marion J.; Beckers, Linda; Toom, Myrthe den; Slutter, Bram; Kuiper, Johan; Duchene, Johan; Aslani, Maria; Megens, Remco T. A.; Veer, Cornelis van 't; Kooij, Gijs; Schrijver, Roy; Hoeksema, Marten A.; Boon, Louis; Fay, Francois; Tang, Jun; Baxter, Samantha; Jongejan, Aldo; Moerland, Perry D.; Vriend, Gert; Bleijlevens, Boris; Fisher, Edward A.; Duivenvoorden, Raphael; Gerdes, Norbert; Winther, Menno P. J. de; Nicolaes, Gerry A.; Mulder, Willem J. M.; Weber, Christian und Lutgens, Esther
(2018):
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
In: Journal of the American College of Cardiology, Bd. 71, Nr. 5: S. 527-542
Aarts, Suzanne A. B. M.; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Pol, Susanne M. A. van der; Zarzycka, Barbara; Heijnen, Priscilla D. A. M.; Beckers, Linda; Toom, Myrthe den; Gijbels, Marion J. J.; Boon, Louis; Weber, Christian; Vries, Helga E. de; Nicolaes, Gerry A. F.; Dijkstra, Christine D.; Kooij, Gijs und Lutgens, Esther
(2017):
Inhibition of CD40-TRAF6 interactions by the small molecule inhibitor 6877002 reduces neuroinflammation.
In: Journal of Neuroinflammation
14:105
[PDF, 3MB]
Berg, Susan M. van den; Dam, Andrea D. van; Kusters, Pascal J. H.; Beckers, Linda; Toom, Myrthe den; Velden, Saskia van der; Bossche, Jan van den; Die, Irma van; Boon, Mariette R.; Rensen, Patrick C. N.; Lutgens, Esther und Winther, Menno P. J. de
(2017):
Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.
In: Journal of Molecular Endocrinology, Bd. 59, Nr. 3: S. 245-255
Döring, Yvonne; Noels, Heidi; Vorst, Emiel P. C. van der; Neideck, Carlos; Egea, Virginia; Drechsler, Maik; Mandl, Manuela; Pawig, Lukas; Jansen, Yvonne; Schröder, Katrin; Bidzhekov, Kiril; Megens, Remco T. A.; Theelen, Wendy; Klinkhammer, Barbara M.; Boor, Peter; Schurgers, Leon; Gorp, Rick van; Ries, Christian; Kusters, Pascal J. H.; Wal, Allard van der; Hackeng, Tilman M.; Gäbel, Gabor; Brandes, Ralf P.; Söhnlein, Oliver; Lutgens, Esther; Vestweber, Dietmar; Teupser, Daniel; Holdt, Lesca M.; Rader, Daniel J.; Saleheen, Danish und Weber, Christian
(2017):
Vascular CXCR4 Limits Atherosclerosis by Maintaining Arterial Integrity Evidence From Mouse and Human Studies.
In: Circulation, Bd. 136, Nr. 4: S. 388-403
[PDF, 3MB]
Berg, Susan M. van den; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Beckers, Linda; Toom, Myrthe; den Smeets, Esther; Levels, Johannes; Winther, Menno P. J. de und Lutgens, Esther
(2016):
Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow.
In: FASEB Journal, Bd. 30, Nr. 5: S. 1779-1788