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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 8
2024
Assfalg, Marlene; Guener, Goekhan; Mueller, Stephan A.; Breimann, Stephan; Langosch, Dieter; Muhle-Goll, Claudia; Frishman, Dmitrij; Steiner, Harald und Lichtenthaler, Stefan F.
(2024):
Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain.
In: Faseb Journal, Bd. 38, Nr. 2, e23442
[PDF, 12MB]
2023
Werner, Nadine T. T.; Hoegel, Philipp; Guener, Gokhan; Stelzer, Walter; Wozny, Manfred; Assfalg, Marlene; Lichtenthaler, Stefan F.; Steiner, Harald und Langosch, Dieter
(2023):
Cooperation of N- and C-terminal substrate transmembrane domain segments in intramembrane proteolysis by γ-secretase.
In: Communications Biology, Bd. 6, Nr. 1, 177
[PDF, 3MB]
2022
Papadopoulou, Alkmini A.; Stelzer, Walter; Silber, Mara; Schlosser, Christine; Spitz, Charlotte; Haug-Kröper, Martina; Straub, Tobias; Mueller, Stephan A.; Lichtenthaler, Stefan F.; Muhle-Goll, Claudia; Langosch, Dieter und Fluhrer, Regina
(2022):
Helical stability of the GnTV transmembrane domain impacts on SPPL3 dependent cleavage.
In: Scientific Reports, Bd. 12, Nr. 1, 20987
[PDF, 2MB]
Guener, Goekhan; Assfalg, Marlene; Zhao, Kai; Dreyer, Tobias; Lahiri, Shibojyoti; Lo, Yun; Slivinschi, Bianca Ionela; Imhof, Axel; Jocher, Georg; Strohm, Laura; Behrends, Christian; Langosch, Dieter; Bronger, Holger; Nimsky, Christopher; Bartsch, Joerg W.; Riddell, Stanley R.; Steiner, Harald und Lichtenthaler, Stefan F.
(2022):
Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for gamma-secretase activity.
In: EMBO Molecular Medicine, Bd. 14, Nr. 10, e16084
[PDF, 1MB]
2020
Heckmeier, Philipp J.; Agam, Ganesh; Teese, Mark G.; Hoyer, Maria; Stehle, Ralf; Lamb, Don C. und Langosch, Dieter
(2020):
Determining the Stoichiometry of Small Protein Oligomers Using Steady-State Fluorescence Anisotropy.
In: Biophysical Journal, Bd. 119, Nr. 1: S. 99-114
Scheidt, Holger A.; Kolocaj, Katja; Konrad, David B.; Frank, James A.; Trauner, Dirk; Langosch, Dieter und Huster, Daniel
(2020):
Light-induced lipid mixing implies a causal role of lipid splay in membrane fusion.
In: Biochimica et Biophysica Acta-Biomembranes, Bd. 1862, Nr. 11, 183438
2019
Götz, Alexander; Mylonas, Nadine; Hoegel, Philipp; Silber, Mara; Heinel, Hannes; Menig, Simon; Vogel, Alexander; Feyrer, Hannes; Huster, Daniel; Luy, Burkhard; Langosch, Dieter; Scharnagl, Christina; Muhle-Goll, Claudia; Kamp, Frits und Steiner, Harald
(2019):
Modulating Hinge Flexibility in the APP Transmembrane Domain Alters gamma-Secretase Cleavage.
In: Biophysical Journal, Bd. 116, Nr. 11: S. 2103-2120
2017
Langosch, Dieter und Steiner, Harald
(2017):
Substrate processing in intramembrane proteolysis by gamma-secretase-the role of protein dynamics.
In: Biological Chemistry, Bd. 398, Nr. 4: S. 441-453