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Anzahl der Publikationen: 9
Zeitschriftenartikel
Riemenschneider, Henrick; Simonetti, Francesca; Sheth, Udit; Katona, Eszter; Roth, Stefan; Hutten, Saskia; Farny, Daniel; Michaelsen, Meike; Nuscher, Brigitte; Schmidt, Michael K.; Flatley, Andrew; Schepers, Aloys; da Silva, Lara Gruijs A.; Zhou, Qihui; Klopstock, Thomas; Liesz, Arthur; Arzberger, Thomas; Herms, Jochen; Feederle, Regina; Gendron, Tania F.; Dormann, Dorothee und Edbauer, Dieter
(2023):
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
In: Acta Neuropathologica Communications, Bd. 11, Nr. 1, 112
[PDF, 6MB]
LaClair, Katherine D.; Zhou, Qihui; Michaelsen, Meike; Wefers, Benedikt; Brill, Monika S.; Janjic, Aleksandar; Rathkolb, Birgit; Farny, Daniel; Cygan, Mikolaj; de Angelis, Martin Hrabe; Wurst, Wolfgang; Neumann, Manuela; Enard, Wolfgang; Misgeld, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2020):
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 121-142
[PDF, 8MB]
Khosravi, Bahram; LaClair, Kathrine D.; Riemenschneider, Henrick; Zhou, Qihui; Frottin, Frederic; Mareljic, Nikola; Czuppa, Mareike; Farny, Daniel; Hartmann, Hannelore; Michaelsen, Meike; Arzberger, Thomas; Hartl, F. Ulrich; Hipp, Mark S. und Edbauer, Dieter
(2020):
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
In: EMBO Journal, Bd. 39, Nr. 8, e102811
[PDF, 2MB]
Zhou, Qihui; Mareljic, Nikola; Michaelsen, Meike; Parhizkar, Samira; Heindl, Steffanie; Nuscher, Brigitte; Farny, Daniel; Czuppa, Mareike; Schludi, Carina; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Feederle, Regina; Roth, Stefan; Haass, Christian; Arzberger, Thomas; Liesz, Arthur und Edbauer, Dieter
(2019):
Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
In: EMBO Molecular Medicine, e10919
[PDF, 969kB]
Hartmann, Hannelore; Hornburg, Daniel; Czuppa, Mareike; Bader, Jakob; Michaelsen, Meike; Farny, Daniel; Arzberger, Thomas; Mann, Matthias; Meissner, Felix und Edbauer, Dieter
(2018):
Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.
In: Life Science Alliance, Bd. 1, Nr. 2, e201800070
[PDF, 3MB]
Schludi, Martin H.; Becker, Lore; Garrett, Lillian; Gendron, Tania F.; Zhou, Qihui; Schreiber, Franziska; Popper, Bastian; Dimou, Leda; Strom, Tim M.; Winkelmann, Juliane; Thaden, Anne von; Rentzsch, Kristin; May, Stephanie; Michaelsen, Meike; Schwenk, Benjamin M.; Tan, Jing; Schoser, Benedikt; Dieterich, Marianne; Petrucelli, Leonard; Hölter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Klopstock, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2017):
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
In: Acta Neuropathologica, Bd. 134, Nr. 2: S. 241-254
Zhou, Qihui; Lehmer, Carina; Michaelsen, Meike; Mori, Kohji; Alterauge, Dominik; Baumjohann, Dirk; Schludi, Martin H.; Greiling, Johanna; Farny, Daniel; Flatley, Andrew; Feederle, Regina; May, Stephanie; Schreiber, Franziska; Arzberger, Thomas; Kuhm, Christoph; Klopstock, Thomas; Hermann, Andreas; Haass, Christian 
ORCID: https://orcid.org/0000-0002-4869-1627 und Edbauer, Dieter
(2017):
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702
ORCID: https://orcid.org/0000-0002-4869-1627 und Edbauer, Dieter
(2017):
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702
Khosravi, Bahram; Hartmann, Hannelore; May, Stephanie; Möhl, Christoph; Ederle, Helena; Michaelsen, Meike; Schludi, Martin H.; Dormann, Dorothee und Edbauer, Dieter
(2017):
Cytoplasmic poly-GA aggregates impair nuclear import of TDP-43 in C9orf72 ALS/FTLD.
In: Human Molecular Genetics, Bd. 26, Nr. 4: S. 790-800
[PDF, 1MB]
Schwenk, Benjamin M.; Hartmann, Hannelore; Serdaroglu, Alperen; Schludi, Martin H.; Hornburg, Daniel; Meissner, Felix; Orozco, Denise; Colombo, Alessio; Tahirovic, Sabina; Michaelsen, Meike; Schreiber, Franziska; Haupt, Simone; Peitz, Michael; Bruestle, Oliver; Küpper, Clemens; Klopstock, Thomas; Otto, Markus; Ludolph, Albert C.; Arzberger, Thomas; Kuhn, Peer-Hendrik und Edbauer, Dieter
(2016):
TDP-43 loss of function inhibits endosomal trafficking and alters trophic signaling in neurons.
In: Embo Journal, Bd. 35, Nr. 21: S. 2350-2370