Anzahl der Publikationen: 8
Zeitschriftenartikel
Czuppa, Mareike; Dhingra, Ashutosh; Zhou, Qihui; Schludi, Carina; Koenig, Laura; Scharf, Elisabeth; Farny, Daniel; Dalmia, Anupriya; Taeger, Joachim; Castillo-Lizardo, Melissa; Katona, Eszter; Mori, Kohji; Aumer, Tina; Schelter, Florian; Mueller, Markus; Carell, Thomas; Kalliokoski, Tuomo; Messinger, Josef; Rizzu, Patrizia; Heutink, Peter und Edbauer, Dieter
(2022):
Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G(4)C(2))(n) expression in C9orf72 ALS/FTD.
In: Cell Reports, Bd. 39, Nr. 10, 110913
[PDF, 3MB]
Mori, Kohji; Gotoh, Shiho; Yamashita, Tomoko; Uozumi, Ryota; Kawabe, Yuya; Tagami, Shinji; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter; Haass, Christian; Nagai, Yoshitaka und Ikeda, Manabu
(2021):
The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene.
In: Journal of Biological Chemistry, Bd. 297, Nr. 4, 101120
[PDF, 2MB]
Nihei, Yoshihiro; Mori, Kohji; Werner, Georg; Arzberger, Thomas; Zhou, Qihui; Khosravi, Barham; Japtok, Julia; Hermann, Andreas; Sommacal, Andreas; Weber, Markus; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter und Haass, Christian
(2019):
Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.
In: Acta Neuropathologica, Bd. 139, Nr. 1: S. 99-118
[PDF, 3MB]
Well, Eva M. van; Bader, Verian; Patra, Maria; Sanchez-Vicente, Ana; Meschede, Jens; Furthmann, Nikolas; Schnack, Cathrin; Blusch, Alina; Longworth, Joseph; Petrasch-Parwez, Elisabeth; Mori, Kohji; Arzberger, Thomas; Truembach, Dietrich; Angersbach, Lena; Showkat, Cathrin; Sehr, Dominik A.; Berlemann, Lena A.; Goldmann, Petra; Clement, Albrecht M.; Behl, Christian; Woerner, Andreas C.; Saft, Carsten; Wurst, Wolfgang; Haass, Christian; Ellrichmann, Gisa; Gold, Ralf; Dittmar, Gunnar; Hipp, Mark S.; Hartl, F. Ulrich; Tatzelt, Jörg und Winklhofer, Konstanze F.
(2019):
A protein quality control pathway regulated by linear ubiquitination.
In: EMBO Journal, Bd. 38, Nr. 9, e100730
[PDF, 2MB]
Zhou, Qihui; Lehmer, Carina; Michaelsen, Meike; Mori, Kohji; Alterauge, Dominik; Baumjohann, Dirk; Schludi, Martin H.; Greiling, Johanna; Farny, Daniel; Flatley, Andrew; Feederle, Regina; May, Stephanie; Schreiber, Franziska; Arzberger, Thomas; Kuhm, Christoph; Klopstock, Thomas; Hermann, Andreas; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Edbauer, Dieter
(2017):
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702
Davidson, Yvonne S.; Flood, Louis; Robinson, Andrew C.; Nihei, Yoshihiro; Mori, Kohji; Rollinson, Sara; Richardson, Anna; Benson, Bridget C.; Jones, Matthew; Snowden, Julie S.; Pickering-Brown, Stuart; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Lashley, Tammaryn und Mann, David M. A.
(2017):
Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene.
In: Acta Neuropathologica Communications
5:31
[PDF, 1MB]
Mori, Kohji; Nihei, Yoshihiro; Arzberger, Thomas; Zhou, Qihui; Mackenzie, Ian R.; Hermann, Andreas; Hanisch, Frank; Kamp, Frits; Nuscher, Brigitte; Orozco, Denise; Edbauer, Dieter und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.
In: Embo Reports, Bd. 17, Nr. 9: S. 1314-1325
Itoh, Naohiro; Okochi, Masayasu; Tagami, Shinji; Nishitomi, Kouhei; Nakayama, Taisuke; Yanagida, Kanta; Fukumori, Akio; Jiang, Jingwei; Mori, Kohji; Hosono, Motoko; Kikuchi, Jyunko; Nakano, Yuko; Takinami, Yoshihiko; Dohi, Keiji; Nishigaki, Atsuko; Takemoto, Hiroshi; Minagawa, Kazuyuki; Katoh, Takaaki; Willem, Michael; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Morihara, Takashi; Tanaka, Toshihisa; Kudo, Takashi; Hasegawa, Hiroshi; Nishimura, Masaki; Sakaguchi, Gaku; Kato, Akira und Takeda, Masatoshi
(2009):
Destruxin E Decreases Beta-Amyloid Generation by Reducing Colocalization of Beta-Amyloid-Cleaving Enzyme 1 and Beta-Amyloid Protein Precursor.
In: Neurodegenerative Diseases, Nr. 5-6: S. 230-239
[PDF, 556kB]
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