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Anzahl der Publikationen: 28
Zeitschriftenartikel
Wilmes, Maximilian; Espinoza, Carolina Pinto; Ludewig, Peter; Stabernack, Joschi; Liesz, Arthur; Nicke, Annette; Gelderblom, Mathias; Gerloff, Christian; Falzoni, Simonetta; Tolosa, Eva; Di Virgilio, Francesco; Rissiek, Bjorn; Plesnilla, Nikolaus; Koch-Nolte, Friedrich und Magnus, Tim
(2022):
Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions.
In: Journal of Neuroinflammation, Bd. 19, Nr. 1, 256
Pinto-Espinoza, Carolina; Guillou, Charlotte; Rissiek, Bjoern; Wilmes, Maximilian; Javidi, Ehsan; Schwarz, Nicole; Junge, Marten; Haag, Friedrich; Liaukouskaya, Nastassia; Wanner, Nicola; Nicke, Annette; Stortelers, Catelijne; Tan, Yossan-Var; Adriouch, Sahil; Magnus, Tim und Koch-Nolte, Friedrich
(2022):
Effective targeting of microglial P2X7 following intracerebroventricular delivery of nanobodies and nanobody-encoding AAVs.
In: Frontiers in Pharmacology, Bd. 13, 1029236
Morgan, James; Moreno, Oscar; Alves, Mariana; Baz, Zurine; Mendez, Aida Menendez; Leister, Hanna; Melia, Ciara; Smith, Jonathon; Visekruna, Alexander; Nicke, Annette; Bhattacharya, Anindya; Ceusters, Marc; Henshall, David C.; Gomez-Vallejo, Vanessa; Llop, Jordi und Engel, Tobias
(2022):
Increased uptake of the P2X7 receptor radiotracer F-18-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
In: Epilepsia, Bd. 64, Nr. 2: S. 511-523
Beamer, Edward; Morgan, James; Alves, Mariana; Menendez Mendez, Aida; Morris, Gareth; Zimmer, Bela; Conte, Giorgia; de Diego-Garcia, Laura; Alarcon-Vila, Cristina; Yiu Ng, Nico Ka; Madden, Stephen; Calzaferri, Francesco; de los Rios, Cristobal; Garcia, Antonio G.; Hamacher, Michael; Dinkel, Klaus; Pelegrin, Pablo; Henshall, David C.; Nicke, Annette und Engel, Tobias
(2022):
Increased expression of the ATP-gated P2X7 receptor reduces responsiveness to anti-convulsants during status epilepticus in mice.
In: British Journal of Pharmacology, Bd. 179, Nr. 12: S. 2986-3006
Tsetlin, Victor; Haufe, Yves; Safronova, Valentina; Serov, Dmitriy; Shadamarshan, Pranavkumar; Son, Lina; Shelukhina, Irina; Kudryavtsev, Denis; Kryukova, Elena; Kasheverov, Igor; Nicke, Annette und Utkin, Yuri
(23. Dezember 2021):
Interaction of α9α10 Nicotinic Receptors With Peptides and Proteins From Animal Venoms.
In: Frontiers in Cellular Neuroscience, Bd. 15, 765541
[PDF, 1MB]
Prades, Silvia; Heard, Gregory; Gale, Jonathan E.; Engel, Tobias; Kopp, Robin; Nicke, Annette; Smith, Katie E. und Jagger, Daniel J.
(2021):
Functional P2X(7) Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia.
In: Journal of Neuroscience, Bd. 41, Nr. 12: S. 2595-2609
Loser, Dominik; Grillberger, Karin; Hinojosa, Maria G.; Blum, Jonathan; Haufe, Yves; Danker, Timm; Johansson, Ylva; Moeller, Clemens; Nicke, Annette; Bennekou, Susanne H.; Gardner, Iain; Bauch, Caroline; Walker, Paul; Forsby, Anna; Ecker, Gerhard F.; Kraushaar, Udo und Leist, Marcel
(2021):
Acute effects of the imidacloprid metabolite desnitro-imidacloprid on human nACh receptors relevant for neuronal signaling.
In: Archives of Toxicology, Bd. 95, Nr. 12: S. 3695-3716
Kollewe, Astrid; Chubanov, Vladimir; Tseung, Fong Tsuen; Correia, Leonor; Schmidt, Eva; Roessig, Anna; Zierler, Susanna; Haupt, Alexander; Mueller, Catrin Swantje; Bildl, Wolfgang; Schulte, Uwe; Nicke, Annette; Fakler, Bernd und Gudermann, Thomas
(2021):
The molecular appearance of native TRPM7 channel complexes identified by high-resolution proteomics.
In: eLife, Bd. 10, e68544
[PDF, 2MB]
Giribaldi, Julien; Haufe, Yves; Evans, Edward R. J.; Wilson, David T.; Daly, Norelle L.; Enjalbal, Christine; Nicke, Annette und Dutertre, Sebastien
(2021):
Synthesis, Structural and Pharmacological Characterizations of CIC, a Novel alpha-Conotoxin with an Extended N-Terminal Tail.
In: Marine Drugs, Bd. 19, Nr. 3, 141
Di Lauro, Caterina; Bianchi, Carolina; Sebastián-Serrano, Álvaro; Soria-Tobar, Lucia; Alvarez-Castelao, Beatriz; Nicke, Annette und Díaz-Hernández, Miguel
(2021):
P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies.
In: Progress in Neurobiology, Bd. 208, 102173
Conte, Giorgia; Menendez-Mendez, Aida; Bauer, Sebastian; El-Naggar, Hany; Alves, Mariana; Nicke, Annette; Delanty, Norman; Rosenow, Felix; Henshall, David C. und Engel, Tobias
(2021):
Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy.
In: Cells, Bd. 10, Nr. 9, 2444
Calzaferri, Francesco; Narros-Fernandez, Paloma; Pascual, Ricardo de; Diego, Antonio M. G. de; Nicke, Annette; Egea, Javier; Garcia, Antonio G. und Rios, Cristobal de los
(2021):
Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation.
In: Journal of Medicinal Chemistry, Bd. 64, Nr. 4: S. 2272-2290
Calovi, Stefano; Mut-Arbona, Paula; Tod, Pal; Iring, Andras; Nicke, Annette; Mato, Susana; Vizi, E. Sylvester; Tonnesen, Jan und Sperlagh, Beata
(November 2020):
P2X7 Receptor-Dependent Layer-Specific Changes in Neuron-Microglia Reactivity in the Prefrontal Cortex of a Phencyclidine Induced Mouse Model of Schizophrenia.
In: Frontiers in Molecular Neuroscience, Bd. 13, 566251: S. 1-23
[PDF, 6MB]
Conte, Giorgia; Nguyen, Ngoc T.; Alves, Mariana; de Diego-Garcia, Laura; Kenny, Aidan; Nicke, Annette; Henshall, David C.; Jimenez-Mateos, Eva M. und Engel, Tobias
(August 2020):
P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice.
In: Frontiers in Molecular Neuroscience, Bd. 13, 127: S. 1-15
[PDF, 3MB]
Wilson, David T.; Bansal, Paramjit S.; Carter, David A.; Vetter, Irina; Nicke, Annette; Dutertre, Sebastien und Daly, Norelle L.
(2020):
Characterisation of a Novel A-Superfamily Conotoxin.
In: Biomedicines, Bd. 8, Nr. 5, 128
Illes, Peter; Müller, Christa E.; Jacobson, Kenneth A.; Grutter, Thomas; Nicke, Annette; Fountain, Samuel J.; Kennedy, Charles; Schmalzing, Gunther; Jarvis, Michael F.; Stojilkovic, Stanko S.; King, Brian F. und Di Virgilio, Francesco
(2020):
Update of P2X receptor properties and their pharmacology: IUPHAR Review 30.
In: British Journal of Pharmacology, Bd. 178, Nr. 3: S. 489-514
Ramirez-Fernandez, Antonio; Urbina-Trevino, Lidia; Conte, Giorgia; Alves, Mariana; Rissiek, Björn; Durner, Anna; Scalbert, Nicolas; Zhang, Jiong; Magnus, Tim; Koch-Nolte, Friedrich; Plesnila, Nikolaus; Deussing, Jan M.; Engel, Tobias; Kopp, Robin und Nicke, Annette
(2020):
Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model.
In: Scientific Reports, Bd. 10, Nr. 1, 19876
[PDF, 8MB]
Giribaldi, Julien; Haufe, Yves; Evans, Edward R. J.; Amar, Muriel; Durner, Anna; Schmidt, Casey; Faucherre, Adele; Maati, Hamid Moha Ou; Enjalbal, Christine; Molgo, Jordi; Servent, Denis; Wilson, David T.; Daly, Norelle L.; Nicke, Annette und Dutertre, Sebastien
(2020):
Backbone Cyclization Turns a Venom Peptide into a Stable and Equipotent Ligand at Both Muscle and Neuronal Nicotinic Receptors.
In: Journal of Medicinal Chemistry, Bd. 63, Nr. 21: S. 12682-12692
Er-Lukowiak, Marco; Duan, Yinghui; Rassendren, Francois; Ulmann, Lauriane; Nicke, Annette; Ufer, Friederike; Friese, Manuel A.; Koch-Nolte, Friedrich; Magnus, Tim und Rissiek, Björn
(2020):
A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice.
In: Iscience, Bd. 23, Nr. 12, 101870
Morgan, James; Alves, Mariana; Conte, Giorgia; Menendez-Mendez, Aida; de Diego-Garcia, Laura; de Leo, Gioacchino; Beamer, Edward; Smith, Jonathon; Nicke, Annette und Engel, Tobias
(2020):
Characterization of the Expression of the ATP-Gated P2X7 Receptor Following Status Epilepticus and during Epilepsy Using a P2X7-EGFP Reporter Mouse.
In: Neuroscience Bulletin, Bd. 36, Nr. 11: S. 1242-1258
T. Pournara, Dimitra; Durner, Anna; Kritsi, Eftichia; Papakostas, Alexios; Zoumpoulakis, Panagiotis; Nicke, Annette und Koufaki, Maria
(2020):
Design, Synthesis, andin vitroEvaluation of P2X7 Antagonists.
In: Chemmedchem, Bd. 15, Nr. 24: S. 2530-2543
Wilting, Fabiola; Kopp, Robin; Gurnev, Philip A.; Schedel, Anna; Dupper, Nathan J.; Kwon, Ohyun; Nicke, Annette; Gudermann, Thomas und Schredelseker, Johann
(2020):
The antiarrhythmic compound efsevin directly modulates voltage‐dependent anion channel 2 by binding to its inner wall and enhancing mitochondrial Ca2+ uptake.
In: British Journal of Pharmacology, Bd. 177, Nr. 13: S. 2947-2958
[PDF, 3MB]
Kopp, Robin; Krautloher, Anna; Ramirez-Fernandez, Antonio und Nicke, Annette
(7. August 2019):
P2X7 Interactions and Signaling - Making Head or Tail of It.
In: Frontiers in Molecular Neuroscience, Bd. 12, 183
[PDF, 2MB]
El Hamdaoui, Yamina; Wu, Xiaosa; Clark, Richard J.; Giribaldi, Julien; Anangi, Raveendra; Craik, David J.; King, Glenn F.; Dutertre, Sebastien; Kaas, Quentin; Herzig, Volker und Nicke, Annette
(31. Mai 2019):
Periplasmic Expression of 4/7 α-Conotoxin TxIA Analogs in E. coli Favors Ribbon Isomer Formation – Suggestion of a Binding Mode at the α7 nAChR.
In: Frontiers in Pharmacology, Bd. 10, 577: S. 1-17
[PDF, 2MB]
Jimenez-Mateos, Eva M.; Smith, Jonathon; Nicke, Annette und Engel, Tobias
(2019):
Regulation of P2X7 receptor expression and function in the brain.
In: Brain Research Bulletin, Bd. 151: S. 153-163
Kaczmarek-Hajek, Karina; Zhang, Jiong; Kopp, Robin; Grosche, Antje; Rissiek, Björn; Saul, Anika; Bruzzone, Santina; Engel, Tobias; Jooss, Tina; Krautloher, Anna; Schuster, Stefanie; Magnus, Tim; Stadelmann, Christine; Sirko, Swetlana; Koch-Nolte, Friedrich; Eulenburg, Volker und Nicke, Annette
(2018):
Re-evaluation of neuronal P2X7 expression using novel mouse models and a P2X7-specific nanobody.
In: eLife, Bd. 7, e36217
[PDF, 10MB]
Giribaldi, Julien; Wilson, David; Nicke, Annette; El Hamdaoui, Yamina; Laconde, Guillaume; Faucherre, Adele; Maati, Hamid Moha Ou; Daly, Norelle L.; Enjalbal, Christine und Dutertre, Sebastien
(2018):
Synthesis, Structure and Biological Activity of CIA and CIB, Two α-Conotoxins from the Predation-Evoked Venom of Conus catus.
In: Toxins, Bd. 10, Nr. 6, 222
[PDF, 2MB]
Leffler, Abba E.; Kuryatov, Alexander; Zebroski, Henry A.; Powell, Susan R.; Filipenko, Petr; Hussein, Adel K.; Gorson, Juliette; Heizmann, Anna; Lyskov, Sergey; Tsien, Richard W.; Poget, Sebastien F.; Nicke, Annette; Lindstrom, Jon; Rudy, Bernardo; Bonneau, Richard und Holford, Mande
(2017):
Discovery of peptide ligands through docking and virtual screening at nicotinic acetylcholine receptor homology models.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 38, E8100-E8109