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Anzahl der Publikationen: 20

Zeitschriftenartikel

Katzdobler, Sabrina ORCID logoORCID: https://orcid.org/0000-0002-3512-5984; Nübling, Georg; Klietz, Martin; Fietzek, Urban M.; Palleis, Carla ORCID logoORCID: https://orcid.org/0000-0002-4331-8145; Bernhardt, Alexander M. ORCID logoORCID: https://orcid.org/0000-0002-2572-5062; Wegner, Florian ORCID logoORCID: https://orcid.org/0000-0002-9931-2666; Huber, Meret; Rogozinski, Sophia; Schneider, Luisa-Sophie; Spruth, Eike Jakob; Beyle, Aline; Vogt, Ina R.; Brandt, Moritz; Hansen, Niels; Glanz, Wenzel ORCID logoORCID: https://orcid.org/0000-0002-5865-4176; Brockmann, Kathrin ORCID logoORCID: https://orcid.org/0000-0002-7515-8596; Spottke, Annika; Hoffmann, Daniel C.; Peters, Oliver; Priller, Josef ORCID logoORCID: https://orcid.org/0000-0001-7596-0979; Wiltfang, Jens ORCID logoORCID: https://orcid.org/0000-0003-1492-5330; Düzel, Emrah ORCID logoORCID: https://orcid.org/0000-0002-0139-5388; Schneider, Anja ORCID logoORCID: https://orcid.org/0000-0001-9540-8700; Falkenburger, Björn; Klockgether, Thomas ORCID logoORCID: https://orcid.org/0000-0001-6174-5442; Gasser, Thomas ORCID logoORCID: https://orcid.org/0000-0002-1069-1146; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Höglinger, Günter ORCID logoORCID: https://orcid.org/0000-0001-7587-6187 und Levin, Johannes ORCID logoORCID: https://orcid.org/0000-0001-5092-4306 (2024): GFAP and NfL as fluid biomarkers for clinical disease severity and disease progression in multiple system atrophy (MSA). In: Journal of Neurology, Bd. 271: S. 6991-6999 [PDF, 1MB]

Hu, Yiying; Hruscha, Alexander; Pan, Chenchen; Schifferer, Martina; Schmidt, Michael K.; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; Giera, Martin; Kostidis, Sarantos; Burhan, Özge; Bebber, Frauke van; Edbauer, Dieter ORCID logoORCID: https://orcid.org/0000-0002-7186-4653; Arzberger, Thomas; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 und Schmid, Bettina ORCID logoORCID: https://orcid.org/0000-0001-8043-7269 (2024): Mis-localization of endogenous TDP-43 leads to ALS-like early-stage metabolic dysfunction and progressive motor deficits. In: Molecular Neurodegeneration, Bd. 19, 50 [PDF, 6MB]

Reich, Marvin ORCID logoORCID: https://orcid.org/0000-0002-4567-0994; Simon, Matthew J. ORCID logoORCID: https://orcid.org/0000-0002-0065-6486; Polke, Beate; Paris, Iñaki ORCID logoORCID: https://orcid.org/0000-0002-3887-0277; Werner, Georg ORCID logoORCID: https://orcid.org/0000-0001-5328-3049; Schrader, Christian; Spieth, Lena; Davis, Sonnet S. ORCID logoORCID: https://orcid.org/0000-0001-7189-1427; Robinson, Sophie ORCID logoORCID: https://orcid.org/0000-0003-1261-1370; de Melo, Gabrielly Lunkes ORCID logoORCID: https://orcid.org/0009-0002-1342-3080; Schlaphoff, Lennart ORCID logoORCID: https://orcid.org/0000-0001-8043-4025; Buschmann, Katrin; Berghoff, Stefan ORCID logoORCID: https://orcid.org/0000-0002-3794-7295; Logan, Todd ORCID logoORCID: https://orcid.org/0000-0003-2081-782X; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; de Weerd, Lis ORCID logoORCID: https://orcid.org/0000-0002-3641-1851; Edbauer, Dieter ORCID logoORCID: https://orcid.org/0000-0002-7186-4653; Simons, Mikael ORCID logoORCID: https://orcid.org/0000-0001-5329-192X; Suh, Jung H. ORCID logoORCID: https://orcid.org/0000-0001-8119-326X; Sandmann, Thomas ORCID logoORCID: https://orcid.org/0000-0002-6601-8890; Kariolis, Mihalis S. ORCID logoORCID: https://orcid.org/0000-0003-2067-4013; DeVos, Sarah L. ORCID logoORCID: https://orcid.org/0000-0003-0921-1763; Lewcock, Joseph W. ORCID logoORCID: https://orcid.org/0000-0003-3012-7881; Paquet, Dominik ORCID logoORCID: https://orcid.org/0000-0003-2065-1639; Capell, Anja ORCID logoORCID: https://orcid.org/0000-0003-3118-911X; Di Paolo, Gilbert ORCID logoORCID: https://orcid.org/0000-0003-1032-1265 und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2024): Peripheral expression of brain-penetrant progranulin rescues pathologies in mouse models of frontotemporal lobar degeneration. In: Science Translational Medicine, Bd. 16, Nr. 750

Eisenhut, Katharina ORCID logoORCID: https://orcid.org/0000-0001-6448-3126; Faber, Jennifer; Engels, Daniel ORCID logoORCID: https://orcid.org/0000-0002-9877-6987; Gerhards, Ramona ORCID logoORCID: https://orcid.org/0000-0002-5398-3632; Lewerenz, Jan ORCID logoORCID: https://orcid.org/0000-0002-9272-529X; Doppler, Kathrin; Sommer, Claudia ORCID logoORCID: https://orcid.org/0000-0002-7064-5002; Markewitz, Robert; Falk, Kim K.; Rössling, Rosa ORCID logoORCID: https://orcid.org/0000-0003-2253-1454; Pruess, Harald; Finke, Carsten ORCID logoORCID: https://orcid.org/0000-0002-7665-1171; Wickel, Jonathan ORCID logoORCID: https://orcid.org/0000-0002-5854-3759; Geis, Christian; Ratuszny, Dominica; Pfeffer, Lena K.; Bittner, Stefan; Piepgras, Johannes; Kraft, Andrea; Klausewitz, Jaqueline; Nuscher, Brigitte ORCID logoORCID: https://orcid.org/0009-0000-4661-0742; Kümpfel, Tania ORCID logoORCID: https://orcid.org/0000-0001-7509-5268 und Thaler, Franziska S. (2024): Early Neuroaxonal Damage in Neurologic Disorders Associated With GAD65 Antibodies. In: Neurology Neuroimmunology & Neuroinflammation, Bd. 11, Nr. 1

Palleis, Carla; Franzmeier, Nicolai; Weidinger, Endy; Bernhardt, Alexander M.; Katzdobler, Sabrina; Wall, Stephan; Ferschmann, Christian; Harris, Stefanie; Schmitt, Julia; Schuster, Sebastian; Gnoerich, Johannes; Finze, Anika; Biechele, Gloria; Lindner, Simon; Albert, Nathalie L.; Bartenstein, Peter; Sabri, Osama; Barthel, Henryk; Rupprecht, Rainer; Nuscher, Brigitte; Stephens, Andrew W.; Rauchmann, Boris-Stephan; Perneczky, Robert; Haass, Christian; Brendel, Matthias; Levin, Johannes und Hoeglinger, Guenter U. (2024): Association of Neurofilament Light Chain, [18F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS. In: Neurology, Bd. 102, Nr. 1, e207901 [PDF, 2MB]

Riemenschneider, Henrick; Simonetti, Francesca; Sheth, Udit; Katona, Eszter; Roth, Stefan; Hutten, Saskia; Farny, Daniel; Michaelsen, Meike; Nuscher, Brigitte; Schmidt, Michael K.; Flatley, Andrew; Schepers, Aloys; da Silva, Lara Gruijs A.; Zhou, Qihui; Klopstock, Thomas; Liesz, Arthur; Arzberger, Thomas; Herms, Jochen; Feederle, Regina; Gendron, Tania F.; Dormann, Dorothee und Edbauer, Dieter (2023): Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo. In: Acta Neuropathologica Communications, Bd. 11, Nr. 1, 112 [PDF, 6MB]

Lotz-Havla, Amelie S.; Katzdobler, Sabrina; Nuscher, Brigitte; Weiß, Katharina; Levin, Johannes; Havla, Joachim und Maier, Esther M. (29. September 2022): Serum glial fibrillary acidic protein and neurofilament light chain in patients with early treated phenylketonuria. In: Frontiers in Neurology, Bd. 13 [PDF, 1MB]

Reifschneider, Anika; Robinson, Sophie; Lengerich, Bettina van; Gnörich, Johannes; Logan, Todd; Heindl, Steffanie; Vogt, Miriam A.; Weidinger, Endy; Riedl, Lina; Wind, Karin; Zatcepin, Artem; Pesaemaa, Ida; Haberl, Sophie; Nuscher, Brigitte; Kleinberger, Gernot; Klimmt, Julien; Götzl, Julia K.; Liesz, Arthur; Bürger, Katharina; Brendel, Matthias; Levin, Johannes; Diehl-Schmid, Janine; Suh, Jung; Di Paolo, Gilbert; Lewcock, Joseph W.; Monroe, Kathryn M.; Paquet, Dominik; Capell, Anja und Haass, Christian (2022): Loss of TREM2 rescues hyperactivation of microglia, but not lysosomal deficits and neurotoxicity in models of progranulin deficiency. In: EMBO Journal, Bd. 41, Nr. 4, e109108 [PDF, 3MB]

Morenas-Rodriguez, Estrella; Li, Yan; Nuscher, Brigitte; Franzmeier, Nicolai; Xiong, Chengjie; Suarez-Calvet, Marc; Fagan, Anne M.; Schultz, Stephanie; Gordon, Brian A.; Benzinger, Tammie L. S.; Hassenstab, Jason; McDade, Eric; Feederle, Regina; Karch, Celeste M.; Schlepckow, Kai; Morris, John C.; Kleinberger, Gernot; Nellgard, Bengt; Voglein, Jonathan; Blennow, Kaj; Zetterberg, Henrik; Ewers, Michael; Jucker, Mathias; Levin, Johannes; Bateman, Randall J. und Haass, Christian (2022): Soluble TREM2 in CSF and its association with other biomarkers and cognition in autosomal-dominant Alzheimer's disease: a longitudinal observational study. In: Lancet Neurology, Bd. 21, Nr. 4: S. 329-341 [PDF, 761kB]

Mori, Kohji; Gotoh, Shiho; Yamashita, Tomoko; Uozumi, Ryota; Kawabe, Yuya; Tagami, Shinji; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter; Haass, Christian; Nagai, Yoshitaka und Ikeda, Manabu (2021): The porphyrin TMPyP4 inhibits elongation during the noncanonical translation of the FTLD/ALS-associated GGGGCC repeat in the C9orf72 gene. In: Journal of Biological Chemistry, Bd. 297, Nr. 4, 101120 [PDF, 2MB]

Schlepckow, Kai; Monroe, Kathryn M.; Kleinberger, Gernot; Cantuti‐Castelvetri, Ludovico; Parhizkar, Samira; Xia, Dan; Willem, Michael; Werner, Georg; Pettkus, Nadine; Brunner, Bettina; Sülzen, Alice; Nuscher, Brigitte; Hampel, Heike; Xiang, Xianyuan; Feederle, Regina; Tahirovic, Sabina; Park, Joshua I.; Prorok, Rachel; Mahon, Cathal; Liang, Chun‐Chi; Shi, Ju; Kim, Do Jin; Sabelström, Hanna; Huang, Fen; Paolo, Gilbert di; Simons, Mikael; Lewcock, Joseph W. und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (7. April 2020): Enhancing protective microglial activities with a dual function TREM2 antibody to the stalk region. , Bd. 12, Nr. 4, e11227 [PDF, 4MB]

Franzmeier, Nicolai; Suarez-Calvet, M.; Frontzkowski, Lukas; Moore, Annah; Hohman, Timothy J.; Morenas-Rodriguez, Estrella; Nuscher, Brigitte; Shaw, Leslie; Trojanowski, John Q.; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X; Kleinberger, Gernot; Haass, Christian und Ewers, Michael (2020): Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration. In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 57 [PDF, 1MB]

Katzmarski, Natalie; Ziegler-Waldkirch, Stephanie; Scheffler, Nina; Witt, Christian; Abou-Ajram, Claudia; Nuscher, Brigitte; Prinz, Marco; Haass, Christian und Meyer-Luehmann, Melanie (2020): A beta oligomers trigger and accelerate A beta seeding. In: Brain Pathology, Bd. 30, Nr. 1: S. 36-45 [PDF, 1MB]

Palleis, Carla; Morenas-Rodriguez, Estrella; Martinez Murcia, Francisco Jesus; Giese, Armin; Nuscher, Brigitte; Haass, Christian; Höglinger, Günter; Bötzel, Kai und Levin, Johannes (2020): Longitudinal correlation between neurofilament light chain and UMSARS in Multiple System Atrophy. In: Clinical Neurology and Neurosurgery, Bd. 195, 105924 [PDF, 345kB]

Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Schlepckow, Kai; Caballero, Miguel Angel Araque; Franzmeier, Nicolai; Capell, Anja; Fellerer, Katrin; Nuscher, Brigitte; Eren, Erden; Levin, Johannes; Deming, Yuetiva; Piccio, Laura; Karch, Celeste M.; Cruchaga, Carlos; Shaw, Leslie M.; Trojanowski, John Q.; Weiner, Michael; Ewers, Michael und Haass, Christian (2019): Early increase of CSF sTREM2 in Alzheimer's disease is associated with tau related-neurodegeneration but not with amyloid- pathology. In: Molecular Neurodegeneration, Bd. 14, 1 [PDF, 1MB]

Parhizkar, Samira; Arzberger, Thomas; Brendel, Matthias; Kleinberger, Gernot; Deussing, Maximilian; Focke, Carola; Nuscher, Brigitte; Xiong, Monica; Ghasemigharagoz, Alireza; Katzmarski, Natalie; Krasemann, Susanne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Colombo, Alessio; Monasor, Laura Sebastian; Tahirovic, Sabina; Herms, Jochen; Willem, Michael; Pettkus, Nadine; Butovsky, Oleg; Bartenstein, Peter; Edbauer, Dieter; Rominger, Axel; Ertuerk, Ali; Grathwohl, Stefan A.; Neher, Jonas J.; Holtzman, David M.; Meyer-Luehmann, Melanie und Haass, Christian (2019): Loss of TREM2 function increases amyloid seeding but reduces plaque-associated ApoE. In: Nature Neuroscience, Bd. 22, Nr. 2 [PDF, 6MB]

Nihei, Yoshihiro; Mori, Kohji; Werner, Georg; Arzberger, Thomas; Zhou, Qihui; Khosravi, Barham; Japtok, Julia; Hermann, Andreas; Sommacal, Andreas; Weber, Markus; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter und Haass, Christian (2019): Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3. In: Acta Neuropathologica, Bd. 139, Nr. 1: S. 99-118 [PDF, 3MB]

Zhou, Qihui; Mareljic, Nikola; Michaelsen, Meike; Parhizkar, Samira; Heindl, Steffanie; Nuscher, Brigitte; Farny, Daniel; Czuppa, Mareike; Schludi, Carina; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Feederle, Regina; Roth, Stefan; Haass, Christian; Arzberger, Thomas; Liesz, Arthur und Edbauer, Dieter (2019): Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model. In: EMBO Molecular Medicine, e10919 [PDF, 969kB]

Mori, Kohji; Nihei, Yoshihiro; Arzberger, Thomas; Zhou, Qihui; Mackenzie, Ian R.; Hermann, Andreas; Hanisch, Frank; Kamp, Frits; Nuscher, Brigitte; Orozco, Denise; Edbauer, Dieter und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2016): Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition. In: Embo Reports, Bd. 17, Nr. 9: S. 1314-1325

Fluhrer, Regina; Kamp, Frits; Grammer, Gudula; Nuscher, Brigitte; Steiner, Harald; Beyer, Klaus und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2011): The Nicastrin ectodomain adopts a highly thermostable structure. In: Biological Chemistry, Bd. 392, Nr. 11: S. 995-1001 [PDF, 1MB]

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