Anzahl der Publikationen: 10
2022
Gruber, Sophia; Löf, Achim; Hausch, Adina; Kutzki, Fabian; Jöhr, Res; Obser, Tobias; König, Gesa; Schneppenheim, Reinhard; Aponte-Santamaria, Camilo; Gräter, Frauke; Brehm, Maria A.; Benoit, Martin und Lipfert, Jan
(2022):
A conformational transition of the D'D3 domain primes von Willebrand factor for multimerization.
In: Blood Advances, Bd. 6, Nr. 17: S. 5198-5209
[PDF, 2MB]
2021
2019
Loef, Achim; Walker, Philipp U.; Sedlak, Steffen M.; Gruber, Sophia; Obser, Tobias; Brehm, Maria A.; Benoit, Martin und Lipfert, Jan
(2019):
Multiplexed protein force spectroscopy reveals equilibrium protein folding dynamics and the low-force response of von Willebrand factor.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 116, Nr. 38: S. 18798-18807
2017
Santamaria, Camilo A. Aponte; Lippok, Svenja; Mittag, Judith J.; Obser, Tobias; Schneppenheim, Reinhard; Baldauf, Carsten; Graeter, Frauke; Budde, Ulrich und Rädler, Joachim O.
(2017):
Mechano-Induced Unfolding of Von Willebrand Factor: A Clinical Example of Protein Destabilization.
In: Biophysical Journal, Bd. 112, Nr. 3:
490A-490A
Aponte-Santamaria, Camilo; Lippok, Svenja; Mittag, Judith J.; Obser, Tobias; Schneppenheim, Reinhard; Baldauf, Carsten; Gräter, Frauke; Budde, Ulrich und Rädler, Joachim O.
(2017):
Mutation G1629E Increases von Willebrand Factor Cleavage via a Cooperative Destabilization Mechanism.
In: Biophysical Journal, Bd. 112, Nr. 1: S. 57-65
2016
Lippok, Svenja; Kolšek, Katra; Löf, Achim; Eggert, Dennis; Vanderlinden, Willem; Müller, Jochen P.; König, Gesa; Obser, Tobias; Röhrs, Karoline; Schneppenheim, Sonja; Budde, Ulrich; Baldauf, Carsten; Aponte-Santamaría, Camilo; Gräter, Frauke; Schneppenheim, Reinhard; Rädler, Joachim O. und Brehm, Maria A.
(2016):
von Willebrand factor is dimerized by protein disulfide isomerase.
In: Blood, Bd. 127, Nr. 9: S. 1183-1191
Mueller, Jochen P.; Mielke, Salomé; Löf, Achim; Obser, Tobias; Beer, Christof; Pippig, Diana A.; Vanderlinden, Willem; Schneppenheim, Reinhard und Benoit, Martin
(2016):
Force Sensing by the Vascular Protein Von Willebrand Factor is Tuned by a Strong Intermonomer Interaction.
In: Biophysical Journal, Bd. 110, Nr. 3:
27A-27A
Lippok, Svenja; Radtke, Matthias; Obser, Tobias; Kleemeier, Lars; Schneppenheim, Reinhard; Budde, Ulrich; Netz, Roland R. und Rädler, Joachim O.
(2016):
Shear-Induced Unfolding and Enzymatic Cleavage of Full-Length VWF Multimers.
In: Biophysical Journal, Bd. 110, Nr. 3: S. 545-554
Müller, Jochen P.; Löf, Achim; Mielke, Salomé; Obser, Tobias; Bruetzel, Linda K.; Vanderlinden, Willem; Lipfert, Jan; Schneppenheim, Reinhard und Benoit, Martin
(2016):
pH-Dependent Interactions in Dimers Govern the Mechanics and Structure of von Willebrand Factor.
In: Biophysical Journal, Bd. 111, Nr. 2: S. 312-322
Müller, Jochen P.; Mielke, Salomé; Löf, Achim; Obser, Tobias; Beer, Christof; Bruetzel, Linda K.; Pippig, Diana A.; Vanderlinden, Willem; Lipfert, Jan; Schneppenheim, Reinhard und Benoit, Martin
(2016):
Force sensing by the vascular protein von Willebrand factor is tuned by a strong intermonomer interaction.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 113, Nr. 5: S. 1208-1213
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