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Anzahl der Publikationen: 19
Zeitschriftenartikel
Gold, Lukas; Barci, Enio; Brendel, Matthias; Orth, Michael; Cheng, Jiying; Kirchleitner, Sabrina V.; Bartos, Laura M.; Poetter, Dennis; Kirchner, Maximilian A.; Unterrainer, Lena M.; Kaiser, Lena; Ziegler, Sibylle; Weidner, Lorraine; Riemenschneider, Markus J.; Unterrainer, Marcus; Belka, Claus; Tonn, Joerg-Christian; Bartenstein, Peter; Niyazi, Maximilian; von Baumgarten, Louisa; Kaelin, Roland E.; Glass, Rainer; Lauber, Kirsten; Albert, Nathalie L. und Holzgreve, Adrien
(2024):
The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma.
In: Biomedicines, Bd. 12, Nr. 1, 188
[PDF, 7MB]
Schnoeller, Leon Emanuel; Albrecht, Valerie; Brix, Nikko; Nieto, Alexander Edward; Fleischmann, Daniel Felix; Niyazi, Maximilian; Hess, Julia; Belka, Claus; Unger, Kristian; Lauber, Kirsten und Orth, Michael
(2022):
Integrative analysis of therapy resistance and transcriptomic profiling data in glioblastoma cells identifies sensitization vulnerabilities for combined modality radiochemotherapy.
In: Radiation Oncology, Bd. 17, Nr. 1, 79
Holzgreve, Adrien; Potter, Dennis; Brendel, Matthias; Orth, Michael; Weidner, Lorraine; Gold, Lukas; Kirchner, Maximilian A.; Bartos, Laura M.; Unterrainer, Lena M.; Unterrainer, Marcus; Steiger, Katja; Baumgarten, Louisa von; Niyazi, Maximilian; Belka, Claus; Bartenstein, Peter; Riemenschneider, Markus J.; Lauber, Kirsten und Albert, Nathalie L.
(2022):
Longitudinal [F-18]GE-180 PET Imaging Facilitates In Vivo Monitoring of TSPO Expression in the GL261 Glioblastoma Mouse Model.
In: Biomedicines, Bd. 10, Nr. 4
[PDF, 2MB]
Orth, Michael; Albrecht, Valerie; Seidl, Karin; Kinzel, Linda; Unger, Kristian; Hess, Julia; Kreutzer, Lisa; Sun, Na; Stegen, Benjamin; Nieto, Alexander; Maas, Jessica; Winssinger, Nicolas; Friedl, Anna A.; Walch, Axel K.; Belka, Claus; Zitzelsberger, Horst; Niyazi, Maximilian und Lauber, Kirsten
(17. März 2021):
Inhibition of HSP90 as a Strategy to Radiosensitize Glioblastoma: Targeting the DNA Damage Response and Beyond.
In: Frontiers in Oncology, Bd. 11, 612354
[PDF, 13MB]
Vounotrypidis, Efstathios; Hillenmayer, Anna; Wertheimer, Christian M.; Athanasiou, Alexis; Siedlecki, Jakob; Orth, Michael; Ohlmann, Andreas; Priglinger, Siegfried G. und Wolf, Armin
(2021):
In vitro evaluation of simulated stereotactic radiotherapy for wet age-related macular degeneration on three different cell lines.
In: Scientific Reports, Bd. 11, Nr. 1, 8068
Schoetz, Ulrike; Klein, Diana; Hess, Julia; Shnayien, Seyd; Spoerl, Steffen; Orth, Michael; Mutlu, Samet; Hennel, Roman; Sieber, Anja; Ganswindt, Ute; Luka, Benedikt; Thomsen, Andreas R.; Unger, Kristian; Jendrossek, Verena; Zitzelsberger, Horst; Bluethgen, Nils; Belka, Claus; Unkel, Steffen; Klinger, Bertram und Lauber, Kirsten
(2021):
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma.
In: Cell Death & Disease, Bd. 12, Nr. 12, 1162
Mahajan, Ujjwal M.; Li, Qi; Alnatsha, Ahmed; Maas, Jessica; Orth, Michael; Maier, Sebastian Hubertus; Peterhansl, Julian; Regel, Ivonne; Sendler, Matthias; Wagh, Preshit R.; Mishra, Neha; Xue, Yonggan; Allawadhi, Prince; Beyer, Georg; Kuehn, Jens-Peter; Marshall, Thomas; Appel, Bettina; Laemmerhirt, Felix; Belka, Claus; Mueller, Sabine; Weiss, Frank-Ulrich; Lauber, Kirsten; Lerch, Markus M. und Mayerle, Julia
(2021):
Tumor-Specific Delivery of 5-Fluorouracil-Incorporated Epidermal Growth Factor Receptor-Targeted Aptamers as an Efficient Treatment in Pancreatic Ductal Adenocarcinoma Models.
In: Gastroenterology, Bd. 161, Nr. 3: S. 996-1010
Schoetz, Ulrike; Klein, Diana; Hess, Julia; Shnayien, Seyd; Spoerl, Steffen; Orth, Michael; Mutlu, Samet; Hennel, Roman; Sieber, Anja; Ganswindt, Ute; Luka, Benedikt; Thomsen, Andreas R.; Unger, Kristian; Jendrossek, Verena; Zitzelsberger, Horst; Blüthgen, Nils; Belka, Claus; Unkel, Steffen; Klinger, Bertram und Lauber, Kirsten 
ORCID: https://orcid.org/0000-0002-8141-0452
(2021):
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma.
In: Cell death & disease, Bd. 12, 1162
[PDF, 5MB]
ORCID: https://orcid.org/0000-0002-8141-0452
(2021):
Early senescence and production of senescence-associated cytokines are major determinants of radioresistance in head-and-neck squamous cell carcinoma.
In: Cell death & disease, Bd. 12, 1162
[PDF, 5MB]
Gennen, Kathrin; Kaesmann, Lukas; Taugner, Julian; Eze, Chukwuka; Karin, Monika; Roengvoraphoj, Olarn; Neumann, Jens; Tufman, Amanda; Orth, Michael; Reu, Simone; Belka, Claus und Manapov, Farkhad
(2020):
Prognostic value of PD-L1 expression on tumor cells combined with CD8+TIL density in patients with locally advanced non-small cell lung cancer treated with concurrent chemoradiotherapy.
In: Radiation Oncology, Bd. 15, Nr. 1, 5
Stegen, Benjamin; Nieto, Alexander; Albrecht, Valerie; Maas, Jessica; Orth, Michael; Neumaier, Klement; Reinhardt, Sabine; Weick-Kleemann, Moritz; Goetz, Wilfried; Reinhart, Merle; Parodi, Katia; Belka, Claus; Niyazi, Maximilian und Lauber, Kirsten
(2020):
Contrast-enhanced, conebeam CT-based, fractionated radiotherapy and follow-up monitoring of orthotopic mouse glioblastoma: a proof-of-concept study.
In: Radiation Oncology, Bd. 15, Nr. 1, 19
Krombach, Julia; Hennel, Roman; Brix, Nikko; Orth, Michael; Schoetz, Ulrike; Ernst, Anne; Schuster, Jessica; Zuchtriegel, Gabriele; Reichel, Christoph A.; Bierschenk, Susanne; Sperandio, Markus; Vogl, Thomas; Unkel, Steffen; Belka, Claus und Lauber, Kirsten
(2019):
Priming anti-tumor immunity by radiotherapy: Dying tumor cell-derived DAMPs trigger endothelial cell activation and recruitment of myeloid cells.
In: Oncoimmunology, Bd. 8, Nr. 1, e1523097
Orth, Michael; Metzger, Philipp; Gerum, Sabine; Mayerle, Julia; Schneider, Guenter; Belka, Claus; Schnurr, Maximilian und Lauber, Kirsten
(2019):
Pancreatic ductal adenocarcinoma: biological hallmarks, current status, and future perspectives of combined modality treatment approaches.
In: Radiation Oncology, Bd. 14, Nr. 1, 141
Jin, Xi-Feng; Auernhammer, Christoph J.; Ilhan, Harun; Lindner, Simon; Nolting, Svenja; Maurer, Julian; Spottl, Gerald und Orth, Michael
(2019):
Combination of 5-Fluorouracil with Epigenetic Modifiers Induces Radiosensitization, Somatostatin Receptor 2 Expression, and Radioligand Binding in Neuroendocrine Tumor Cells In Vitro.
In: Journal of Nuclear Medicine, Bd. 60, Nr. 9: S. 1240-1246
Fankhauser, Maria; Bechmann, Nicole; Lauseker, Michael; Goncalves, Judith; Favier, Judith; Klink, Barbara; William, Doreen; Gieldon, Laura; Maurer, Julian; Spöttl, Gerald; Rank, Petra; Knösel, Thomas; Orth, Michael; Ziegler, Christian G.; Aristizabal Prada, Elke Tatjana; Rubinstein, German; Fassnacht, Martin; Spitzweg, Christine; Grossman, Ashley B.; Pacak, Karel; Beuschlein, Felix; Bornstein, Stefan R.; Eisenhofer, Graeme; Auernhammer, Christoph J.; Reincke, Martin und Nölting, Svenja
(2019):
Synergistic Highly Potent Targeted Drug Combinations in different Pheochromocytoma Models including Human Tumor Cultures.
In: Endocrinology, Bd. 160, Nr. 11: S. 2600-2617
Aristizabal Prada, Elke Tatjana; Weis, Carla; Orth, Michael; Lauseker, Michael; Spöttl, Gerald; Maurer, Julian; Grabowski, Patricia; Grossman, Ashley; Auernhammer, Christoph Josef und Nölting, Svenja
(2. Oktober 2018):
GSK3α/β: A Novel Therapeutic Target for Neuroendocrine Tumors?
In: Neuroendocrinology, Bd. 106, Nr. 4: S. 335-351
Prada, Elke Tatjana Aristizabal; Orth, Michael; Nölting, Svenja; Spöttl, Gerald; Maurer, Julian und Auernhammer, Christoph
(2017):
The MTH1 inhibitor TH588 demonstrates anti-tumoral effects alone and in combination with everolimus, 5-FU and gamma-irradiation in neuroendocrine tumor cells.
In: PLOS One 12(5), e0178375 [PDF, 15MB]
In: PLOS One 12(5), e0178375 [PDF, 15MB]
Hess, Julia; Unger, Kristian; Orth, Michael; Schötz, Ulrike; Schüttrumpf, Lars; Zangen, Verena; Gimenez-Aznar, Igor; Michna, Agata; Schneider, Ludmila; Stamp, Ramona; Selmansberger, Martin; Braselmann, Herbert; Hieber, Ludwig; Drexler, Guido A.; Kuger, Sebastian; Klein, Diana; Jendrossek, Verena; Friedl, Anna A.; Belka, Claus; Zitzelsberger, Horst und Lauber, Kirsten
(2017):
Genomic amplification of Fanconi anemia complementation group A (FancA) in head and neck squamous cell carcinoma (HNSCC): Cellular mechanisms of radioresistance and clinical relevance.
In: Cancer Letters, Bd. 386: S. 87-99
Kinzel, Linda; Ernst, Anne; Orth, Michael; Albrecht, Valerie; Hennel, Roman; Brix, Nikko; Frey, Benjamin; Gaipl, Udo S.; Zuchtriegel, Gabriele; Reichel, Christoph A.; Blutke, Andreas; Schilling, Daniela; Multhoff, Gabriele; Li, Minglun; Niyazi, Maximilian; Friedl, Anna A.; Winssinger, Nicolas; Belka, Claus und Lauber, Kirsten
(2016):
A novel HSP90 inhibitor with reduced hepatotoxicity synergizes with radiotherapy to induce apoptosis, abrogate clonogenic survival, and improve tumor control in models of colorectal cancer.
In: Oncotarget, Bd. 7, Nr. 28: S. 43199-43219
Hocke, Sandra; Guo, Yang; Job, Albert; Orth, Michael; Ziesch, Andreas; Lauber, Kirsten; De Toni, Enrico N.; Gress, Thomas M.; Herbst, Andreas; Göke, Burkhard und Gallmeier, Eike
(2016):
A synthetic lethal screen identifies ATR-inhibition as a novel therapeutic approach for POLD1-deficient cancers.
In: Oncotarget, Bd. 7, Nr. 6: S. 7080-7095