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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 15
2024
Schewe, Denis M.; Vogiatzi, Fotini; Münnich, Ira A.; Zeller, Tobias; Windisch, Roland; Wichmann, Christian; Müller, Kristina; Bhat, Hilal; Felix, Elisa; Mougiakakos, Dimitrios; Bruns, Heiko; Lenk, Lennart; Valerius, Thomas; Humpe, Andreas; Peipp, Matthias und Kellner, Christian 
ORCID: https://orcid.org/0000-0002-2562-6902
(2024):
Enhanced potency of immunotherapy against B‐cell precursor acute lymphoblastic leukemia by combination of an Fc‐engineered CD19 antibody and CD47 blockade.
In: HemaSphere, Bd. 8, Nr. 2
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-2562-6902
(2024):
Enhanced potency of immunotherapy against B‐cell precursor acute lymphoblastic leukemia by combination of an Fc‐engineered CD19 antibody and CD47 blockade.
In: HemaSphere, Bd. 8, Nr. 2
[PDF, 1MB]
Windisch, Roland ORCID: https://orcid.org/0000-0003-1294-5151; Soliman, Sarah; Hoffmann, Adrian; Chen-Wichmann, Linping ORCID: https://orcid.org/0009-0003-8439-8107; Danese, Anna; Vosberg, Sebastian ORCID: https://orcid.org/0000-0002-8464-1483; Bravo, Jimena; Lutz, Sebastian; Kellner, Christian ORCID: https://orcid.org/0000-0002-2562-6902; Fischer, Alexander ORCID: https://orcid.org/0000-0001-8876-5566; Gebhard, Claudia ORCID: https://orcid.org/0000-0002-5459-8381; Redondo Monte, Enric; Hartmann, Luise; Schneider, Stephanie; Beier, Fabian ORCID: https://orcid.org/0000-0002-3718-8217; Strobl, Carolin Dorothea ORCID: https://orcid.org/0000-0003-2257-6281; Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373; Peipp, Matthias; Schündeln, Michael ORCID: https://orcid.org/0000-0001-7495-9060; Stricker, Stefan H. ORCID: https://orcid.org/0000-0002-5488-8530; Rehli, Michael ORCID: https://orcid.org/0000-0003-3992-932X; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652; Humpe, Andreas; Klump, Hannes ORCID: https://orcid.org/0000-0003-3536-1212; Brendel, Christian ORCID: https://orcid.org/0000-0003-4081-4351; Krause, Daniela S. ORCID: https://orcid.org/0000-0003-3603-1119; Greif, Philipp A. ORCID: https://orcid.org/0000-0002-3744-7936 und Wichmann, Christian
(2024):
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
In: Proceedings of the National Academy of Sciences, Bd. 121, Nr. 25, e2312499121
[PDF, 6MB]
ORCID: https://orcid.org/0000-0003-1294-5151; Soliman, Sarah; Hoffmann, Adrian; Chen-Wichmann, Linping ORCID: https://orcid.org/0009-0003-8439-8107; Danese, Anna; Vosberg, Sebastian ORCID: https://orcid.org/0000-0002-8464-1483; Bravo, Jimena; Lutz, Sebastian; Kellner, Christian ORCID: https://orcid.org/0000-0002-2562-6902; Fischer, Alexander ORCID: https://orcid.org/0000-0001-8876-5566; Gebhard, Claudia ORCID: https://orcid.org/0000-0002-5459-8381; Redondo Monte, Enric; Hartmann, Luise; Schneider, Stephanie; Beier, Fabian ORCID: https://orcid.org/0000-0002-3718-8217; Strobl, Carolin Dorothea ORCID: https://orcid.org/0000-0003-2257-6281; Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373; Peipp, Matthias; Schündeln, Michael ORCID: https://orcid.org/0000-0001-7495-9060; Stricker, Stefan H. ORCID: https://orcid.org/0000-0002-5488-8530; Rehli, Michael ORCID: https://orcid.org/0000-0003-3992-932X; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652; Humpe, Andreas; Klump, Hannes ORCID: https://orcid.org/0000-0003-3536-1212; Brendel, Christian ORCID: https://orcid.org/0000-0003-4081-4351; Krause, Daniela S. ORCID: https://orcid.org/0000-0003-3603-1119; Greif, Philipp A. ORCID: https://orcid.org/0000-0002-3744-7936 und Wichmann, Christian
(2024):
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
In: Proceedings of the National Academy of Sciences, Bd. 121, Nr. 25, e2312499121
[PDF, 6MB]
2022
Zeller, Tobias; Lutz, Sebastian; Münnich, Ira A.; Windisch, Roland; Hilger, Patricia; Herold, Tobias; Tahiri, Natyra; Banck, Jan C.; Weigert, Oliver; Moosmann, Andreas; von Bergwelt-Baildon, Michael; Flamann, Cindy; Bruns, Heiko; Wichmann, Christian; Baumann, Niklas; Valerius, Thomas; Schewe, Denis M.; Peipp, Matthias; Rösner, Thies; Humpe, Andreas und Kellner, Christian
(27. Oktober 2022):
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
In: Frontiers in Immunology, Bd. 13
[PDF, 21MB]
Klausz, Katja; Kellner, Christian; Gehlert, Carina Lynn; Krohn, Steffen; Wilcken, Hauke; Floerkemeier, Inken; Günther, Andreas; Bauerschlag, Dirk O.; Clement, Bernd; Gramatzki, Martin und Peipp, Matthias
(2022):
The Novel Dual Topoisomerase Inhibitor P8-D6 Shows Anti-myeloma Activity In Vitro and In Vivo.
In: Molecular Cancer Therapeutics, Bd. 21, Nr. 1: S. 70-78
Mueller, Kristina; Vogiatzi, Fotini; Winterberg, Dorothee; Rosner, Thies; Lenk, Lennart; Bastian, Lorenz; Gehlert, Carina L.; Autenrieb, Marie-Pauline; Bruggemann, Monika; Cario, Gunnar; Schrappe, Martin; Kulozik, Andreas E.; Eckert, Cornelia; Bergmann, Anke K.; Bornhauser, Beat; Bourquin, Jean-Pierre; Valerius, Thomas; Peipp, Matthias; Kellner, Christian und Schewe, Denis M.
(2022):
Combining daratumumab with CD47 blockade prolongs survival in preclinical models of pediatric T-ALL.
In: Blood, Bd. 140, Nr. 1: S. 45-57
Vogiatzi, Fotini; Heymann, Julia; Müller, Kristina; Winterberg, Dorothee; Drakul, Aneta; Rösner, Thies; Lenk, Lennart; Heib, Michelle; Gehlert, Carina Lynn; Cario, Gunnar; Schrappe, Martin; Claviez, Alexander; Bornhauser, Beat; Bourquin, Jean-Pierre; Bomken, Simon; Adam, Dieter; Frielitz, Fabian-Simon; Maecker-Kolhoff, Britta; Stanulla, Martin; Valerius, Thomas; Peipp, Matthias; Kellner, Christian und Schewe, Denis M.
(2022):
Venetoclax enhances the efficacy of therapeutic antibodies in B-cell malignancies by augmenting tumor cell phagocytosis.
In: Blood Advances, Bd. 6, Nr. 16: S. 4847-4858
Baumann, Niklas; Arndt, Christian; Petersen, Judith; Lustig, Marta; Roesner, Thies; Klausz, Katja; Kellner, Christian; Bultmann, Miriam; Bastian, Lorenz; Vogiatzi, Fotini; Leusen, Jeanette H. W.; Burger, Renate; Schewe, Denis M.; Peipp, Matthias und Valerius, Thomas
(2022):
Myeloid checkpoint blockade improves killing of T-acute lymphoblastic leukemia cells by an IgA2 variant of daratumumab.
In: Frontiers in Immunology, Bd. 13, 949140
Peipp, Matthias; Klausz, Katja; Boje, Ammelie Svea; Zeller, Tobias; Zielonka, Stefan und Kellner, Christian
(2022):
Immunotherapeutic targeting of activating natural killer cell receptors and their ligands in cancer.
In: Clinical and Experimental Immunology, Bd. 209, Nr. 1: S. 22-32
2021
Baumann, Niklas; Roesner, Thies; Jansen, J. H. Marco; Chan, Chilam; Eichholz, Klara Marie; Klausz, Katja; Winterberg, Dorothee; Mueller, Kristina; Humpe, Andreas; Burger, Renate; Peipp, Matthias; Schewe, Denis M.; Kellner, Christian; Leusen, Jeanette H. W. und Valerius, Thomas
(2021):
Enhancement of epidermal growth factor receptor antibody tumor immunotherapy by glutaminyl cyclase inhibition to interfere with CD47/signal regulatory protein alpha interactions.
In: Cancer Science, Bd. 112, Nr. 8: S. 3029-3040
Evers, Mitchell; Roesner, Thies; Duenkel, Anna; Jansen, J. H. Marco; Baumann, Niklas; Ten Broeke, Toine; Nederend, Maaike; Eichholz, Klara; Klausz, Katja; Reiding, Karli; Schewe, Denis M.; Kellner, Christian; Peipp, Matthias; Leusen, Jeanette H. W. und Valerius, Thomas
(2021):
The selection of variable regions affects effector mechanisms of IgA antibodies against CD20.
In: Blood Advances, Bd. 5, Nr. 19: S. 3807-3820
Kellner, Christian; Lutz, Sebastian; Oberg, Hans-Heinrich; Wesch, Daniela; Otte, Anna; Diemer, Katarina J.; Wilcken, Hauke; Bauerschlag, Dirk; Glueer, Claus-Christian; Wichmann, Christian; Kabelitz, Dieter; Leusen, Jeanette H. W.; Klausz, Katja; Humpe, Andreas; Gramatzki, Martin und Peipp, Matthias
(2021):
Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen.
In: Biological Chemistry, Bd. 403, Nr. 5-6: S. 545-556
Klausz, Katja; Cieker, Michael; Kellner, Christian; Roesner, Thies; Otte, Anna; Krohn, Steffen; Lux, Anja; Nimmerjahn, Falk; Valerius, Thomas; Gramatzki, Martin und Peipp, Matthias
(2021):
Fc-engineering significantly improves the recruitment of immune effector cells by anti-ICAM-1 antibody MSH-TP15 for myeloma therapy.
In: Haematologica, Bd. 106, Nr. 7: S. 1857-1866
Winterberg, Dorothee; Lenk, Lennart; Osswald, Maren; Vogiatzi, Fotini; Gehlert, Carina Lynn; Frielitz, Fabian-Simon; Klausz, Katja; Roesner, Thies; Valerius, Thomas; Trauzold, Anna; Peipp, Matthias; Kellner, Christian und Schewe, Denis Martin
(2021):
Engineering of CD19 Antibodies: A CD19-TRAIL Fusion Construct Specifically Induces Apoptosis in B-Cell Precursor Acute Lymphoblastic Leukemia (BCP-ALL) Cells In Vivo.
In: Journal of Clinical Medicine, Bd. 10, Nr. 12, 2634
2020
Rosskopf, Sophia; Eichholz, Klara Marie; Winterberg, Dorothee; Diemer, Katarina Julia; Lutz, Sebastian; Muennich, Ira Alexandra; Klausz, Katja; Roesner, Thies; Valerius, Thomas; Schewe, Denis Martin; Humpe, Andreas; Gramatzki, Martin; Peipp, Matthias und Kellner, Christian
(2020):
Enhancing CDC and ADCC of CD19 Antibodies by Combining Fc Protein-Engineering with Fc Glyco-Engineering.
In: Antibodies, Bd. 9, Nr. 4, 63
2019
Vogiatzi, Fotini; Winterberg, Dorothee; Lenk, Lennart; Buchmann, Swantje; Cario, Gunnar; Schrappe, Martin; Peipp, Matthias; Richter-Pechanska, Paulina; Kulozik, Andreas E.; Lentes, Jana; Bergmann, Anke K.; Valerius, Thomas; Frielitz, Fabian-Simon; Kellner, Christian und Schewe, Denis M.
(2019):
Daratumumab eradicates minimal residual disease in a preclinical model of pediatric T-cell acute lymphoblastic leukemia.
In: Blood, Bd. 134, Nr. 8: S. 713-716