Anzahl der Publikationen: 18
Zeitschriftenartikel
Kopczak, Anna; Stringer, Michael S.; Brink, Hilde van den; Kerkhofs, Danielle; Blair, Gordon W.; Dinther, Maud van; Reyes, Carmen Arteaga; Garcia, Daniela Jaime; Wartolowska, Karolina A.; Thrippleton, Michael J.; Kampaite, Agniete; Duering, Marco; Staals, Julie; Lesnik-Oberstein, Saskia; Muir, Keith W.; Middeke, Martin; Norrving, Bo; Bousser, Marie-Germaine; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Rothwell, Peter M.; Doubal, Fergus N.; Oostenbrugge, Robert van; Biessels, Geert Jan; Webb, Alastair J. S.; Wardlaw, Joanna M.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Jaime Garcia, Daniela; Onkenhout, Laurien; André, Elisabeth; Kääb, Stefan ORCID: https://orcid.org/0000-0001-8824-3581; Anders, Hans-Joachim; Hack, Remco; Kaffe, Maria; Dewenter, Anna und Malik, Rainer
(2023):
Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
In: Lancet Neurology, Bd. 22, Nr. 11: S. 991-1004
Kopczak, Anna ORCID: https://orcid.org/0000-0002-5037-2342; Stringer, Michael S. ORCID: https://orcid.org/0000-0002-3811-4439; Brink, Hilde van den ORCID: https://orcid.org/0000-0003-3094-0274; Kerkhofs, Danielle; Blair, Gordon W. ORCID: https://orcid.org/0000-0002-8756-8007; Dinther, Maud van; Onkenhout, Laurien; Wartolowska, Karolina A.; Thrippleton, Michael J.; Duering, Marco; Staals, Julie ORCID: https://orcid.org/0000-0002-9502-6937; Middeke, Martin; André, Elisabeth; Norrving, Bo; Bousser, Marie-Germaine; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Rothwell, Peter M. ORCID: https://orcid.org/0000-0001-9739-9211; N Doubal, Fergus; Oostenbrugge, Robert van; Biessels, Geert Jan; Webb, Alastair J. S. ORCID: https://orcid.org/0000-0002-0630-8204; Wardlaw, Joanna M. ORCID: https://orcid.org/0000-0002-9812-6642 und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2023):
The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.
In: European Stroke Journal, Bd. 8, Nr. 1: S. 387-397
[PDF, 1MB]
Jaworek, Thomas; Xu, Huichun; Gaynor, Brady J.; Cole, John W.; Rannikmae, Kristiina; Stanne, Tara M.; Tomppo, Liisa; Abedi, Vida; Amouyel, Philippe; Armstrong, Nicole D.; Attia, John; Bell, Steven; Benavente, Oscar R.; Boncoraglio, Giorgio B.; Butterworth, Adam; Carcel-Marquez, Jara; Chen, Zhengming; Chong, Michael; Cruchaga, Carlos; Cushman, Mary; Danesh, John; Debette, Stephanie; Duggan, David J.; Durda, Jon Peter; Engstrom, Gunnar; Enzinger, Chris; Faul, Jessica D.; Fecteau, Natalie S.; Fernandez-Cadenas, Israel; Gieger, Christian; Giese, Anne-Katrin; Grewal, Raji P.; Grittner, Ulrike; Havulinna, Aki S.; Heitsch, Laura; Hochberg, Marc C.; Holliday, Elizabeth; Hu, Jie; Ilinca, Andreea; Irvin, Marguerite R.; Jackson, Rebecca D.; Jacob, Mina A.; Rabionet, Raquel; Jimenez-Conde, Jordi; Johnson, Julie A.; Kamatani, Yoichiro; Kardia, Sharon L. R.; Koido, Masaru; Kubo, Michiaki; Lange, Leslie; Lee, Jin-Moo; Lemmens, Robin; Levi, Christopher R.; Li, Jiang; Li, Liming; Lin, Kuang; Lopez, Haley; Luke, Sothear; Maguire, Jane; McArdle, Patrick F.; McDonough, Caitrin W.; Meschia, James F.; Metso, Tiina; Müller-Nurasyid, Martina; O'Connor, Timothy D.; O'Donnell, Martin; Peddareddygari, Leema R.; Pera, Joanna; Perry, James A.; Peters, Annette; Putaala, Jukka; Ray, Debashree; Rexrode, Kathryn; Ribases, Marta; Rosand, Jonathan; Rothwell, Peter M.; Rundek, Tatjana; Ryan, Kathleen A.; Sacco, Ralph L.; Salomaa, Veikko; Sanchez-Mora, Cristina; Schmidt, Reinhold; Sharma, Pankaj; Slowik, Agnieszka; Smith, Jennifer A.; Smith, Nicholas L.; Wassertheil-Smoller, Sylvia; Soderholm, Martin; Stine, O. Colin; Strbian, Daniel; Sudlow, Cathie L. M.; Tatlisumak, Turgut; Terao, Chikashi; Thijs, Vincent; Torres-Aguila, Nuria P.; Tregouet, David-Alexandre; Tuladhar, Anil M.; Veldink, Jan H.; Walters, Robin G.; Weir, David R.; Woo, Daniel; Worrall, Bradford B.; Hong, Charles C.; Ross, Owen A.; Zand, Ramin; Leeuw, Frank-Erik de; Lindgren, Arne G.; Pare, Guillaume; Anderson, Christopher D.; Markus, Hugh S.; Jern, Christina; Malik, Rainer; Dichgans, Martin; Mitchell, Braxton D. und Kittner, Steven J.
(2022):
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke.
In: Neurology, Bd. 99, Nr. 16, E1738-E1754
[PDF, 693kB]
Mishra, Aniket; Malik, Rainer; Hachiya, Tsuyoshi; Jürgenson, Tuuli; Namba, Shinichi; Posner, Daniel C.; Kamanu, Frederick K.; Koido, Masaru; Le Grand, Quentin; Shi, Mingyang; He, Yunye; Georgakis, Marios K.; Caro, Ilana; Krebs, Kristi; Liaw, Yi-Ching; Vaura, Felix C.; Lin, Kuang; Winsvold, Bendik Slagsvold; Srinivasasainagendra, Vinodh; Parodi, Livia; Bae, Hee-Joon; Chauhan, Ganesh; Chong, Michael R.; Tomppo, Liisa; Akinyemi, Rufus; Roshchupkin, Gennady V.; Habib, Naomi; Jee, Yon Ho; Thomassen, Jesper Qvist; Abedi, Vida; Carcel-Marquez, Jara; Nygaard, Marianne; Leonard, Hampton L.; Yang, Chaojie; Yonova-Doing, Ekaterina; Knol, Maria J.; Lewis, Adam J.; Judy, Renae L.; Ago, Tetsuro; Amouyel, Philippe; Armstrong, Nicole D.; Bakker, Mark K.; Bartz, Traci M.; Bennett, David A.; Bis, Joshua C.; Bordes, Constance; Borte, Sigrid; Cain, Anael; Ridker, Paul M.; Cho, Kelly; Chen, Zhengming; Cruchaga, Carlos; Cole, John W.; Jager, Phil L. de; Cid, Rafael de; Endres, Matthias; Ferreira, Leslie E.; Geerlings, Mirjam I.; Gasca, Natalie C.; Gudnason, Vilmundur; Hata, Jun; He, Jing; Heath, Alicia K.; Ho, Yuk-Lam; Havulinna, Aki S.; Hopewell, Jemma C.; Hyacinth, Hyacinth I.; Inouye, Michael; Jacob, Mina A.; Jeon, Christina E.; Jern, Christina; Kamouchi, Masahiro; Keene, Keith L.; Kitazono, Takanari; Kittner, Steven J.; Konuma, Takahiro; Kumar, Amit; Lacaze, Paul; Launer, Lenore J.; Lee, Keon-Joo; Lepik, Kaido; Li, Jiang; Li, Liming; Manichaikul, Ani; Markus, Hugh S.; Marston, Nicholas A.; Meitinger, Thomas; Mitchell, Braxton D.; Montellano, Felipe A.; Morisaki, Takayuki; Mosley, Thomas H.; Nalls, Mike A.; Nordestgaard, Borge G.; O'Donnell, Martin J.; Okada, Yukinori; Onland-Moret, N. Charlotte; Ovbiagele, Bruce; Peters, Annette; Psaty, Bruce M.; Rich, Stephen S.; Rosand, Jonathan; Sabatine, Marc S.; Sacco, Ralph L.; Saleheen, Danish; Sandset, Else Charlotte; Salomaa, Veikko; Sargurupremraj, Muralidharan; Sasaki, Makoto; Satizabal, Claudia L.; Schmidt, Carsten O.; Shimizu, Atsushi; Smith, Nicholas L.; Sloane, Kelly L.; Sutoh, Yoichi; Sun, Yan V.; Tanno, Kozo; Tiedt, Steffen; Tatlisumak, Turgut; Torres-Aguila, Nuria P.; Tiwari, Hemant K.; Tregouet, David-Alexandre; Trompet, Stella; Tuladhar, Anil Man; Tybjaerg-Hansen, Anne; Vugt, Marion van; Vibo, Riina; Verma, Shefali S.; Wiggins, Kerri L.; Wennberg, Patrik; Woo, Daniel; Wilson, Peter W. F.; Xu, Huichun; Yang, Qiong; Yoon, Kyungheon; Bis, Joshua C.; Bis, Joshua C.; Lee, Jin-Moo; Cheng, Yu-Ching; Meschia, James F.; Chen, Wei Min; Sale, Michele M.; Zonderman, Alan B.; Evans, Michele K.; Wilson, James G.; Correa, Adolfo; Traylor, Matthew; Lewis, Cathryn M.; Carty, Cara L.; Reiner, Alexander; Haessler, Jeffrey; Langefeld, Carl D.; Gottesman, Rebecca F.; Yaffe, Kristine; Liu, Yong Mei; Kooperberg, Charles; Lange, Leslie A.; Furie, Karen L.; Arnett, Donna K.; Benavente, Oscar R.; Grewal, Raji P.; Peddareddygari, Leema Reddy; Kooperberg, Charles; Kooperberg, Charles; Hveem, Kristian; Lindstrom, Sara; Wang, Lu; Smith, Erin N.; Gordon, William; Hylckama Vlieg, Astrid van; de Andrade, Mariza; Brody, Jennifer A.; Pattee, Jack W.; Haessler, Jeffrey; Brumpton, Ben M.; Suchon, Pierre; Chen, Ming-Huei; Frazer, Kelly A.; Turman, Constance; Germain, Marine; MacDonald, James; Braekkan, Sigrid K.; Armasu, Sebastian M.; Pankratz, Nathan; Jackson, Rebecca D.; Nielsen, Jonas B.; Giulianini, Franco; Puurunen, Marja K.; Ibrahim, Manal; Heckbert, Susan R.; Bammler, Theo K.; McCauley, Bryan M.; Taylor, Kent D.; Pankow, James S.; Reiner, Alexander P.; Gabrielsen, Maiken E.; Deleuze, Jean-Francois; O'Donnell, Chris J.; Kim, Jihye; McKnight, Barbara; Kraft, Peter; Hansen, John-Bjarne; Rosendaal, Frits R.; Heit, John A.; Tang, Weihong; Morange, Pierre-Emmanuel; Johnson, Andrew D.; Kabrhel, Christopher; Dijk, Ewoud J. van; Dijk, Ewoud J. van; Koudstaal, Peter J.; Luijckx, Gert-Jan; Nederkoorn, Paul J.; Oostenbrugge, Robert J. van; Visser, Marieke C.; Wermer, Marieke J. H.; Kappelle, L. Jaap; Esko, Tonu; Esko, Tonu; Metspalu, Andres; Magi, Reedik; Nelis, Mari; Irvin, Marguerite R.; Irvin, Marguerite R.; de Leeuw, Frank-Erik; Levi, Christopher R.; Maguire, Jane; Jimenez-Conde, Jordi; Sharma, Pankaj; Sudlow, Cathie L. M.; Rannikmae, Kristiina; Schmidt, Reinhold; Slowik, Agnieszka; Pera, Joanna; Thijs, Vincent N. S.; Lindgren, Arne G.; Ilinca, Andreea; Melander, Olle; Engstrom, Gunnar; Rexrode, Kathryn M.; Rothwell, Peter M.; Stanne, Tara M.; Johnson, Julie A.; Danesh, John; Butterworth, Adam S.; Heitsch, Laura; Boncoraglio, Giorgio B.; Kubo, Michiaki; Pezzini, Alessandro; Rolfs, Arndt; Giese, Anne-Katrin; Weir, David; Jackson, Rebecca D.; Ross, Owen A.; Lemmons, Robin; Soderholm, Martin; Cushman, Mary; Jood, Katarina; McDonough, Caitrin W.; Bell, Steven; Linkohr, Birgit; Lee, Tsong-Hai; Putaala, Jukka; Anderson, Christopher D.; Anderson, Christopher D.; Lopez, Oscar L.; Jian, Xueqiu; Schminke, Ulf; Cullell, Natalia; Delgado, Pilar; Ibanez, Laura; Krupinski, Jerzy; Lioutas, Vasileios; Matsuda, Koichi; Montaner, Joan; Muino, Elena; Roquer, Jaume; Sarnowski, Chloe; Sattar, Naveed; Sibolt, Gerli; Teumer, Alexander; Rutten-Jacobs, Loes; Kanai, Masahiro; Giese, Anne-Katrin; Gretarsdottir, Solveig; Rost, Natalia S.; Yusuf, Salim; Almgren, Peter; Ay, Hakan; Bevan, Steve; Brown, Robert D.; Carrera, Caty; Buring, Julie E.; Chen, Wei-Min; Cotlarciuc, Ioana; de Bakker, Paul I. W.; DeStefano, Anita L.; Hoed, Marcel den; Duan, Qing; Engelter, Stefan T.; Falcone, Guido J.; Gottesman, Rebecca F.; Gustafsson, Stefan; Hassan, Ahamad; Holliday, Elizabeth G.; Howard, George; Hsu, Fang-Chi; Ingelsson, Erik; Harris, Tamara B.; Kissela, Brett M.; Kleindorfer, Dawn O.; Langenberg, Claudia; Lemmens, Robin; Leys, Didier; Lin, Wei-Yu; Lorentzen, Erik; Magnusson, Patrik K.; McArdle, Patrick F.; Pulit, Sara L.; Rice, Kenneth; Sakaue, Saori; Sapkota, Bishwa R.; Tanislav, Christian; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tzourio, Christophe; Duijn, Cornelia M. van; Walters, Matthew; Wareham, Nicholas J.; Amin, Najaf; Aparicio, Hugo J.; Attia, John; Beiser, Alexa S.; Berr, Claudine; Bustamante, Mariana; Caso, Valeria; Choi, Seung Hoan; Chowhan, Ayesha; Dartigues, Jean-Francois; Delavaran, Hossein; Dorr, Marcus; Ford, Ian; Gurpreet, Wander S.; Hamsten, Anders; Hozawa, Atsushi; Ingelsson, Martin; Iwasaki, Motoki; Kaffashian, Sara; Kalra, Lalit; Kjartansson, Olafur; Kloss, Manja; Labovitz, Daniel L.; Laurie, Cathy C.; Li, Linxin; Lind, Lars; Lindgren, Cecilia M.; Makoto, Hirata; Minegishi, Naoko; Morris, Andrew P.; Müller-Nurasyid, Martina; Norrving, Bo; Ogishima, Soichi; Parati, Eugenio A.; Pedersen, Nancy L.; Perola, Markus; Jousilahti, Pekka; Pileggi, Silvana; Rabionet, Raquel; Riba-Llena, Iolanda; Ribases, Marta; Romero, Jose R.; Rudd, Anthony G.; Sarin, Antti-Pekka; Sarju, Ralhan; Satoh, Mamoru; Sawada, Norie; Sigurdsson, Asgeir; Smith, Albert; Stine, O. Colin; Stott, David J.; Strauch, Konstantin; Takai, Takako; Tanaka, Hideo; Touze, Emmanuel; Tsugane, Shoichiro; Uitterlinden, Andre G.; Valdimarsson, Einar M.; Lee, Sven J. van der; Wakai, Kenji; Williams, Stephen R.; Wolfe, Charles D. A.; Wong, Quenna; Yamaji, Taiki; Sanghera, Dharambir K.; Stefansson, Kari; Taylor, Kent D.; Martinez-Majander, Nicolas; Sobue, Kenji; Soriano-Tarraga, Carolina; Volzke, Henry; Akpa, Onoja; Akpa, Onoja; Sarfo, Fred S.; Akpalu, Albert; Obiako, Reginald; Wahab, Kolawole; Osaigbovo, Godwin; Owolabi, Lukman; Komolafe, Morenikeji; Jenkins, Carolyn; Arulogun, Oyedunni; Ogbole, Godwin; Adeoye, Abiodun M.; Akinyemi, Joshua; Agunloye, Atinuke; Fakunle, Adekunle G.; Uvere, Ezinne; Olalere, Abimbola; Adebajo, Olayinka J.; Chen, Junshi; Chen, Junshi; Clarke, Robert; Collins, Rory; Guo, Yu; Wang, Chen; Lv, Jun; Peto, Richard; Chen, Yiping; Fairhurst-Hunter, Zammy; Hill, Michael; Pozarickij, Alfred; Schmidt, Dan; Stevens, Becky; Turnbull, Iain; Yu, Canqing; Le Grand, Quentin; Le Grand, Quentin; Ferreira, Leslie E.; Nagai, Akiko; Nagai, Akiko; Murakami, Yoishinori; Geerlings, Mirjam I.; Geerlings, Mirjam I.; Gasca, Natalie C.; Gudnason, Vilmundur; Vugt, Marion van; Gottesman, Rebecca F.; Shiroma, Eric J.; Sigurdsson, Sigurdur; Ghanbari, Mohsen; Boerwinkle, Eric; Beiser, Alexa S.; Fongang, Bernard; Wang, Ruiqi; Ikram, Mohammad K.; Volker, Uwe; de Jager, Phil L.; de Jager, Phil L.; de Cid, Rafael; Nordestgaard, Borge G.; Sargurupremraj, Muralidharan; Verma, Shefali S.; de Laat, Karlijn F.; de Laat, Karlijn F.; Norden, Anouk G. W. van; de Kort, Paul L.; Vermeer, Sarah E.; Brouwers, Paul J. A. M.; Gons, Rob A. R.; Nederkoorn, Paul J.; den Heijer, Tom; Dijk, Gert W. van; Rooij, Frank G. W. van; Aamodt, Anne H.; Aamodt, Anne H.; Skogholt, Anne H.; Brumpton, Ben M.; Willer, Cristen J.; Heuch, Ingrid; Hagen, Knut; Fritsche, Lars G.; Pedersen, Linda M.; Gabrielsen, Maiken E.; Ellekjaer, Hanne; Zhou, Wei; Martinsen, Amy E.; Kristoffersen, Espen S.; Nielsen, Jonas B.; Hveem, Kristian; Thomas, Laurent F.; Kleinschnitz, Christoph; Kleinschnitz, Christoph; Frantz, Stefan; Ungethum, Kathrin; Gallego-Fabrega, Cristina; Gallego-Fabrega, Cristina; Lledos, Miquel; Llucia-Carol, Laia; Sobrino, Tomas; Campos, Francisco; Castillo, Jose; Freijo, Marimar; Arenillas, Juan Francisco; Obach, Victor; Alvarez-Sabin, Jose; Molina, Carlos A.; Ribo, Marc; Munoz-Narbona, Lucia; Lopez-Cancio, Elena; Millan, Monica; Diaz-Navarro, Rosa; Vives-Bauza, Cristofol; Serrano-Heras, Gemma; Segura, Tomas; Delgado, Pilar; Dhar, Rajat; Delgado-Mederos, Raquel; Prats-Sanchez, Luis; Camps-Renom, Pol; Blay, Natalia; Sumoy, Lauro; Marti-Fabregas, Joan; Schnohr, Peter; Schnohr, Peter; Jensen, Gorm B.; Benn, Marianne; Afzal, Shoaib; Kamstrup, Pia R.; Setten, Jessica van; Laan, Sander W. van der; Vonk, Jet M. J.; Kim, Bong-Jo; Kim, Bong-Jo; Curtze, Sami; Curtze, Sami; Tiainen, Marjaana; Kinnunen, Janne; Menon, Vilas; Menon, Vilas; Sung, Yun Ju; Yang, Chengran; Saillour-Glenisson, Florence; Gravel, Simon; Onland-Moret, N. Charlotte; Onland-Moret, N. Charlotte; Heath, Alicia K.; Millwood, Iona Y.; Gieger, Christian; Ninomiya, Toshiharu; Grabe, Hans J.; Jukema, J. Wouter; Rissanen, Ina L.; Strbian, Daniel; Kim, Young Jin; Chen, Pei-Hsin; Mayerhofer, Ernst; Howson, Joanna M. M.; Irvin, Marguerite R.; Adams, Hieab; Wassertheil-Smoller, Sylvia; Christensen, Kaare; Ikram, Mohammad A.; Rundek, Tatjana; Worrall, Bradford B.; Lathrop, G. Mark; Riaz, Moeen; Simonsick, Eleanor M.; Korv, Janika; Franca, Paulo H. C.; Zand, Ramin; Prasad, Kameshwar; Frikke-Schmidt, Ruth; de Leeuw, Frank-Erik; Liman, Thomas; Haeusler, Karl Georg; Ruigrok, Ynte M.; Heuschmann, Peter Ulrich; Longstreth, W. T.; Jung, Keum Ji; Bastarache, Lisa; Pare, Guillaume; Damrauer, Scott M.; Chasman, Daniel I.; Rotter, Jerome I.; Anderson, Christopher D.; Zwart, John-Anker; Niiranen, Teemu J.; Fornage, Myriam; Liaw, Yung-Po; Seshadri, Sudha; Fernandez-Cadenas, Israel; Walters, Robin G.; Ruff, Christian T.; Owolabi, Mayowa O.; Huffman, Jennifer E.; Milani, Lili und Kamatani, Yoichiro
(2022):
Stroke genetics informs drug discovery and risk prediction across ancestries.
In: Nature, Bd. 611, Nr. 7934: S. 115-123
[PDF, 16MB]
Traylor, Matthew; Persyn, Elodie; Tomppo, Liisa; Klasson, Sofia; Abedi, Vida; Bakker, Mark K.; Torres, Nuria; Li, Linxin; Bell, Steven; Rutten-Jacobs, Loes; Tozer, Daniel J.; Griessenauer, Christoph J.; Zhang, Yanfei; Pedersen, Annie; Sharma, Pankaj; Jimenez-Conde, Jordi; Rundek, Tatjana; Grewal, Raji P.; Lindgren, Arne; Meschia, James F.; Salomaa, Veikko; Havulinna, Aki; Kourkoulis, Christina; Crawford, Katherine; Marini, Sandro; Mitchell, Braxton D.; Kittner, Steven J.; Rosand, Jonathan; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Zand, Ramin; Ruigrok, Ynte; Rost, Natalia; Lemmens, Robin; Rothwell, Peter M.; Anderson, Christopher D.; Wardlaw, Joanna; Lewis, Cathryn M. und Markus, Hugh S.
(2021):
Genetic basis of lacunar stroke: a pooled analysis of individual patient data and genome-wide association studies.
In: Lancet Neurology, Bd. 20, Nr. 5: S. 351-361
[PDF, 1MB]
Traylor, Matthew; Tozer, Daniel J.; Croall, Iain D.; Ford, Danuta M. Lisiecka; Olorunda, Abiodun Olubunmi; Boncoraglio, Giorgio; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Lemmens, Robin; Rosand, Jonathan; Rost, Natalia S.; Rothwell, Peter M.; Sudlow, Cathie L. M.; Thijs, Vincent; Rutten-Jacobs, Loes und Markus, Hugh S.
(2019):
Genetic variation in PLEKHG1 is associated with white matter hyperintensities (n=11,226).
In: Neurology, Bd. 92, Nr. 8, E749-E757
[PDF, 399kB]
Valdes-Marquez, Elsa; Parish, Sarah; Clarke, Robert; Stari, Traiani; Worrall, Bradford B.; Hopewell, Jemma C.; Slowik, Agnieszka; Hofman, Albert; Algra, Ale; Reiner, Alex P.; Doney, Alexander S. F.; Gschwendtner, Andreas; Ilinca, Andreea; Giese, Anne-Katrin; Lindgren, Arne; Vicente, Astrid M.; Norrving, Bo; Nordestgaard, Borge G.; Mitchell, Braxton D.; Psaty, Bruce M.; Carty, Cara L.; Sudlow, Cathie L. M.; Anderson, Christopher; Levi, Christopher R.; Satizabal, Claudia L.; Palmer, Colin N. A.; Gamble, Dale M.; Woo, Daniel; Saleheen, Danish; Ringelstein, E. Bernd; Valdimarsson, Einar M.; Holliday, Elizabeth G.; Davies, Gail; Chauhan, Ganesh; Pasterkamp, Gerard; Boncoraglio, Giorgio B.; Kuhlenbaeumer, Gregor; Thorleifsson, Gudmar; Falcone, Guido J.; Pare, Guillaume; Schmidt, Helena; Delavaran, Hossein; Markus, Hugh S.; Aparicio, Hugo J.; Deary, Ian; Cotlarciuc, Ioana; Fernandez-Cadenas, Israel; Meschia, James F.; Liu, Jingmin; Montaner, Joan; Pera, Joanna; Cole, John; Attia, John R.; Rosand, Jonathan; Ferro, Jose M.; Bis, Joshua C.; Furie, Karen; Stefansson, Kari; Berger, Klaus; Kostulas, Konstantinos; Rannikmae, Kristiina; Ikram, M. Arfan; Benn, Marianne; Dichgans, Martin; Pandolfo, Massimo; Traylor, Matthew; Walters, Matthew; Sale, Michele; Nalls, Michael A.; Fornage, Myriam; van Zuydam, Natalie R.; Sharma, Pankaj; Abrantes, Patricia; de Bakker, Paul I. W.; Higgins, Peter; Lichtner, Peter; Rothwell, Peter M.; Amouyel, Philippe; Yang, Qiong; Malik, Rainer; Schmidt, Reinhold; Lemmens, Robin; van der Laan, Sander W.; Pulit, Sara L.; Abboud, Sherine; Oliveira, Sofia A.; Gretarsdottir, Solveig; Debette, Stephanie; Williams, Stephen R.; Bevan, Steve; Kittner, Steven J.; Seshadri, Sudha; Mosley, Thomas; Battey, Thomas W. K.; Tatlisumak, Turgut; Thorsteinsdottir, Unnur; Thijs, Vincent N. S.; Longstreth, W. T.; Zhao, Wei; Chen, Wei-Min und Cheng, Yu-Ching
(2019):
Relative effects of LDL-C on ischemic stroke and coronary disease A Mendelian randomization study.
In: Neurology, Bd. 92, Nr. 11, E1176-E1187
Malik, Rainer; Chauhan, Ganesh; Traylor, Matthew; Sargurupremraj, Muralidharan; Okada, Yukinori; Mishra, Aniket; Rutten-Jacobs, Loes; Giese, Anne-Katrin; Laan, Sander W. van der; Gretarsdottir, Solveig; Anderson, Christopher D.; Chong, Michael; Adams, Hieab H. H.; Ago, Tetsuro; Almgren, Peter; Amouyel, Philippe; Ay, Hakan; Bartz, Traci M.; Benavente, Oscar R.; Bevan, Steve; Boncoraglio, Giorgio B.; Brown, Robert D. Jr.; Butterworth, Adam S.; Carrera, Caty; Carty, Cara L.; Chasman, Daniel I.; Chen, Wei-Min; Cole, John W.; Correa, Adolfo; Cotlarciuc, Ioana; Cruchaga, Carlos; Danesh, John; Bakker, Paul I. W. de; DeStefano, Anita L.; Hoed, Marcel den; Duan, Qing; Engelter, Stefan T.; Falcone, Guido J.; Gottesman, Rebecca F.; Grewal, Raji P.; Gudnason, Vilmundur; Gustafsson, Stefan; Haessler, Jeffrey; Harris, Tamara B.; Hassan, Ahamad; Havulinna, Aki S.; Heckbert, Susan R.; Holliday, Elizabeth G.; Howard, George; Hsu, Fang-Chi; Hyacinth, Hyacinth I.; Ikram, M. Arfan; Ingelsson, Erik; Irvin, Marguerite R.; Jian, Xueqiu; Jimenez-Conde, Jordi; Johnson, Julie A.; Jukema, J. Wouter; Kanai, Masahiro; Keene, Keith L.; Kissela, Brett M.; Kleindorfer, Dawn O.; Kooperberg, Charles; Kubo, Michiaki; Lange, Leslie A.; Langefeld, Carl D.; Langenberg, Claudia; Launer, Lenore J.; Lee, Jin-Moo; Lemmens, Robin; Leys, Didier; Lewis, Cathryn M.; Lin, Wei-Yu; Lindgren, Arne G.; Lorentzen, Erik; Magnusson, Patrik K.; Maguire, Jane; Manichaikul, Ani; McArdle, Patrick F.; Meschia, James F.; Mitchell, Braxton D.; Mosley, Thomas H.; Nalls, Michael A.; Ninomiya, Toshiharu; O'Donnell, Martin J.; Psaty, Bruce M.; Pulit, Sara L.; Rannikmae, Kristiina; Reiner, Alexander P.; Rexrode, Kathryn M.; Rice, Kenneth; Rich, Stephen S.; Ridker, Paul M.; Rost, Natalia S.; Rothwell, Peter M.; Rotter, Jerome I.; Rundek, Tatjana; Sacco, Ralph L.; Sakaue, Saori; Sale, Michele M.; Salomaa, Veikko; Sapkota, Bishwa R.; Schmidt, Reinhold; Schmidt, Carsten O.; Schminke, Ulf; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L. M.; Tanislav, Christian; Tatlisumak, Turgut; Taylor, Kent D.; Thijs, Vincent N. S.; Thorleifsson, Gudmar; Thorsteinsdottir, Unnur; Tiedt, Steffen; Trompet, Stella; Tzourio, Christophe; van Duijn, Cornelia M.; Walters, Matthew; Wareham, Nicholas J.; Wassertheil-Smoller, Sylvia; Wilson, James G.; Wiggins, Kerri L.; Yang, Qiong; Yusuf, Salim; Bis, Joshua C.; Pastinen, Tomi; Ruusalepp, Arno; Schadt, Eric E.; Koplev, Simon; Bjorkegren, Johan L. M.; Codoni, Veronica; Civelek, Mete; Smith, Nicholas L.; Trégouët, David-Alexandre ORCID: https://orcid.org/0000-0001-9084-7800; Christophersen, Ingrid E.; Roselli, Carolina; Lubitz, Steven A.; Ellinor, Patrick T.; Tai, E. Shyong; Kooner, Jaspal S.; Kato, Norihiro; He, Jiang; Harst, Pim van der; Elliott, Paul; Chambers, John C.; Takeuchi, Fumihiko; Johnson, Andrew D.; Sanghera, Dharambir K.; Melander, Olle; Jern, Christina; Strbian, Daniel; Fernandez-Cadenas, Israel; Longstreth, W. T. Jr.; Rolfs, Arndt; Hata, Jun; Woo, Daniel; Rosand, Jonathan; Pare, Guillaume; Hopewell, Jemma C.; Saleheen, Danish; Stefansson, Kari; Worrall, Bradford B.; Kittner, Steven J.; Seshadri, Sudha; Fornage, Myriam; Markus, Hugh S.; Howson, Joanna M. M.; Kamatani, Yoichiro; Debette, Stephanie und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2018):
Multiancestry genome-wide association study of 520,000 subjects identifies 32 loci associated with stroke and stroke subtypes.
In: Nature Genetics, Bd. 50, Nr. 4: S. 524-537
Lubitz, Steven A.; Parsons, Owen E.; Anderson, Christopher D.; Benjamin, Emelia J.; Malik, Rainer; Weng, Lu-Chen; Dichgans, Martin; Sudlow, Cathie L.; Rothwell, Peter M.; Rosand, Jonathan; Ellinor, Patrick T.; Markus, Hugh S. und Traylor, Matthew
(2017):
Atrial Fibrillation Genetic Risk and Ischemic Stroke Mechanisms.
In: Stroke, Bd. 48, Nr. 6: S. 1451-1456
Traylor, Matthew; Malik, Rainer; Nalls, Mike A.; Cotlarciuc, Ioana; Radmanesh, Farid; Thorleifsson, Gudmar; Hanscombe, Ken B.; Langefeld, Carl; Saleheen, Danish; Rost, Natalia S.; Yet, Idil; Spector, Tim D.; Bell, Jordana T.; Hannon, Eilis; Mill, Jonathan; Chauhan, Ganesh; Debette, Stephanie; Bis, Joshua C.; Longstreth, W. T.; Ikram, M. Arfan; Launer, Lenore J.; Seshadri, Sudha; Hamilton-Bruce, Monica Anne; Jimenez-Conde, Jordi; Cole, John W.; Schmidt, Reinhold; Slowik, Agnieszka; Lemmens, Robin; Lindgren, Arne; Melander, Olle; Grewal, Raji P.; Sacco, Ralph L.; Rundek, Tatjana; Rexrode, Kathryn; Arnett, Donna K.; Johnson, Julie A.; Benavente, Oscar R.; Wasssertheil-Smoller, Sylvia; Lee, Jin-Moo; Pulit, Sara L.; Wong, Quenna; Rich, Stephen S.; Bakker, Paul I. W. de; McArdle, Patrick F.; Woo, Daniel; Anderson, Christopher D.; Xu, Huichun; Heitsch, Laura; Fornage, Myriam; Jern, Christina; Stefansson, Kari; Thorsteinsdottir, Unnur; Gretarsdottir, Solveig; Lewis, Cathryn M.; Sharma, Pankaj; Sudlow, Cathie L. M.; Rothwell, Peter M.; Boncoraglio, Giorgio B.; Thijs, Vincent; Levi, Chris; Meschia, James F.; Rosand, Jonathan; Kittner, Steven J.; Mitchell, Braxton D.; Dichgans, Martin; Worrall, Bradford B. und Markus, Hugh S.
(2017):
Genetic Variation at 16q24.2 Is Associated With Small Vessel Stroke.
In: Annals of Neurology, Bd. 81, Nr. 3: S. 383-394
[PDF, 532kB]
Malik, Rainer; Dau, Therese; Gonik, Maria; Sivakumar, Anirudh; Deredge, Daniel J.; Edeleva, Evgeniia V.; Götzfried, Jessica; Laan, Sander W. van der; Pasterkamp, Gerard; Beaufort, Nathalie; Seixas, Susana; Bevan, Steve; Lincz, Lisa F.; Holliday, Elizabeth G.; Burgess, Annette I.; Rannikmae, Kristiina; Minnerup, Jens; Kriebel, Jennifer; Waldenberger, Melanie; Müller-Nurasyid, Martina; Lichtner, Peter; Saleheen, Danish; Rothwell, Peter M.; Levi, Christopher; Attia, John; Sudlow, Cathie L. M.; Braun, Dieter; Markus, Hugh S.; Wintrode, Patrick L.; Berger, Klaus; Jenne, Dieter E. und Dichgans, Martin
(2017):
Common coding variant in SERPINA1 increases the risk for large artery stroke.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 14: S. 3613-3618
[PDF, 1MB]
Traylor, Matthew; Rutten-Jacobs, Loes C. A.; Thijs, Vincent; Holliday, Elizabeth G.; Levi, Chris; Bevan, Steve; Malik, Rainer; Boncoraglio, Giorgio; Sudlow, Cathie; Rothwell, Peter M.; Dichgans, Martin und Markus, Hugh S.
(2016):
Genetic Associations With White Matter Hyperintensities Confer Risk of Lacunar Stroke.
In: Stroke, Bd. 47, Nr. 5: S. 1174-1179
Rutten-Jacobs, Loes C. A.; Traylor, Matthew; Adib-Samii, Poneh; Thijs, Vincent; Sudlow, Cathie; Rothwell, Peter M.; Boncoraglio, Giorgio; Dichgans, Martin; Meschia, James; Maguire, Jane; Levi, Christopher; Rost, Natalia S.; Rosand, Jonathan; Hassan, Ahamad; Bevan, Steve und Markus, Hugh S.
(2016):
Association of MTHFR C677T Genotype With Ischemic Stroke Is Confined to Cerebral Small Vessel Disease Subtype.
In: Stroke, Bd. 47, Nr. 3: S. 646-651
Cheng, Yu-Ching; Stanne, Tara M.; Giese, Anne-Katrin; Ho, Weang Kee; Traylor, Matthew; Amouyel, Philippe; Holliday, Elizabeth G.; Malik, Rainer; Xu, Huichun; Kittner, Steven J.; Cole, John W.; O'Connell, Jeffrey R.; Danesh, John; Rasheed, Asif; Zhao, Wei; Engelter, Stefan; Grond-Ginsbach, Caspar; Kamatani, Yoichiro; Lathrop, Mark; Leys, Didier; Thijs, Vincent; Metso, Tiina M.; Tatlisumak, Turgut; Pezzini, Alessandro; Parati, Eugenio A.; Norrving, Bo; Bevan, Steve; Rothwell, Peter M.; Sudlow, Cathie; Slowik, Agnieszka; Lindgren, Arne; Walters, Matthew R.; Jannes, Jim; Shen, Jess; Crosslin, David; Doheny, Kimberly; Laurie, Cathy C.; Kanse, Sandip M.; Bis, Joshua C.; Fornage, Myriam; Mosley, Thomas H.; Hopewell, Jemma C.; Strauch, Konstantin; Müller-Nurasyid, Martina; Gieger, Christian; Waldenberger, Melanie; Peters, Annette; Meisinger, Christine; Ikram, M. Arfan; Longstreth, W. T.; Meschia, James F.; Seshadri, Sudha; Sharma, Pankaj; Worrall, Bradford; Jern, Christina; Levi, Christopher; Dichgans, Martin; Boncoraglio, Giorgio B.; Markus, Hugh S.; Debette, Stephanie; Rolfs, Arndt; Saleheen, Danish und Mitchell, Braxton D.
(2016):
Genome-Wide Association Analysis of Young-Onset Stroke Identifies a Locus on Chromosome 10q25 Near HABP2.
In: Stroke, Bd. 47, Nr. 2: S. 307-316
Malik, Rainer; Traylor, Matthew; Pulit, Sara L.; Bevan, Steve; Hopewell, Jemma C.; Holliday, Elizabeth G.; Zhao, Wei; Abrantes, Patricia; Amouyel, Philippe; Attia, John R.; Battey, Thomas W. K.; Berger, Klaus; Boncoraglio, Giorgio B.; Chauhan, Ganesh; Cheng, Yu-Ching; Chen, Wei-Min; Clarke, Robert; Cotlarciuc, Ioana; Debette, Stephanie; Falcone, Guido J.; Ferro, Jose M.; Gamble, Dale M.; Ilinca, Andreea; Kittner, Steven J.; Kourkoulis, Christina E.; Lemmens, Robin; Levi, Christopher R.; Lichtner, Peter; Lindgren, Arne; Liu, Jingmin; Meschia, James F.; Mitchell, Braxton D.; Oliveira, Sofia A.; Pera, Joana; Reiner, Alex P.; Rothwell, Peter M.; Sharma, Pankaj; Slowik, Agnieszka; Sudlow, Cathie L. M.; Tatlisumak, Turgut; Thijs, Vincent; Vicente, Astrid M.; Woo, Daniel; Seshadri, Sudha; Saleheen, Danish; Rosand, Jonathan; Markus, Hugh S.; Worrall, Bradford B. und Dichgans, Martin
(2016):
Low-frequency and common genetic variation in ischemic stroke The METASTROKE collaboration.
In: Neurology, Bd. 86, Nr. 13: S. 1217-1226
Traylor, Matthew; Zhang, Cathy R.; Adib-Samii, Poneh; Devan, William J.; Parsons, Owen E.; Lanfranconi, Silvia; Gregory, Sarah; Cloonan, Lisa; Falcone, Guido J.; Radmanesh, Farid; Fitzpatrick, Kaitlin; Kanakis, Allison; Barrick, Thomas R.; Moynihan, Barry; Lewis, Cathryn M.; Boncoraglio, Giorgio B.; Lemmens, Robin; Thijs, Vincent; Sudlow, Cathie; Wardlaw, Joanna; Rothwell, Peter M.; Meschia, James F.; Worrall, Bradford B.; Levi, Christopher; Bevan, Steve; Furie, Karen L.; Dichgans, Martin; Rosand, Jonathan; Markus, Hugh S. und Rost, Natalia
(2016):
Genome-wide meta-analysis of cerebral white matter hyperintensities in patients with stroke.
In: Neurology, Bd. 86, Nr. 2: S. 146-153
Seppälä, Ilkka; Kleber, Marcus E.; Bevan, Steve; Lyytikäinen, Leo-Pekka; Oksala, Niku; Hernesniemi, Jussi A.; Mäkelä, Kari-Matti; Rothwell, Peter M.; Sudlow, Cathie; Dichgans, Martin; Mononen, Nina; Vlachopoulou, Efthymia; Sinisalo, Juha; Delgado, Graciela E.; Laaksonen, Reijo; Koskinen, Tuomas; Scharnagl, Hubert; Kähönen, Mika; Markus, Hugh S.; März, Winfried und Lehtimäki, Terho
(2016):
Associations of functional alanine-glyoxylate aminotransferase 2 gene variants with atrial fibrillation and ischemic stroke.
In: Scientific Reports, Bd. 6, 23207
[PDF, 800kB]
Traylor, Matthew; Mäkelä, Kari-Matti; Kilarski, Laura L.; Holliday, Elizabeth G.; Devan, William J.; Nalls, Mike A.; Wiggins, Kerri L.; Zhao, Wei; Cheng, Yu-Ching; Achterberg, Sefanja; Malik, Rainer; Sudlow, Cathie; Bevan, Steve; Raitoharju, Emma; Oksala, Niku; Thijs, Vincent; Lemmens, Robin; Lindgren, Arne; Slowik, Agnieszka; Maguire, Jane M.; Walters, Matthew; Algra, Ale; Sharma, Pankaj; Attia, John R.; Boncoraglio, Giorgio B.; Rothwell, Peter M.; Bakker, Paul I. W. de; Bis, Joshua C.; Saleheen, Danish; Kittner, Steven J.; Mitchell, Braxton D.; Rosand, Jonathan; Meschia, James F.; Levi, Christopher; Dichgans, Martin; Lehtimäki, Terho; Lewis, Cathryn M. und Markus, Hugh S.
(2014):
A Novel MMP12 Locus Is Associated with Large Artery Atherosclerotic Stroke Using a Genome-Wide Age-at-Onset Informed Approach.
In: PLOS Genetics
10(7), e1004469
[PDF, 1MB]
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