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Anzahl der Publikationen: 19
Zeitschriftenartikel
Groll, Tanja; Silva, Miguel; Sarker, Rim Sabrina Jahan; Tschurtschenthaler, Markus; Schnalzger, Theresa; Mogler, Carolin; Denk, Daniela; Schoelch, Sebastian; Schraml, Barbara U.; Ruland, Jürgen; Rad, Roland; Saur, Dieter; Weichert, Wilko; Jesinghaus, Moritz; Matiasek, Kaspar und Steiger, Katja
(2022):
Comparative Study of the Role of Interepithelial Mucosal Mast Cells in the Context of Intestinal Adenoma-Carcinoma Progression.
In: Cancers, Bd. 14, Nr. 9, 2248
Orben, Felix; Lankes, Katharina; Schneeweis, Christian; Hassan, Zonera; Jakubowsky, Hannah; Krauss, Lukas; Boniolo, Fabio; Schneider, Carolin; Schaefer, Arlett; Murr, Janine; Schlag, Christoph; Kong, Bo; Oellinger, Rupert; Wang, Chengdong; Beyer, Georg; Mahajan, Ujjwal M.; Xue, Yonggan; Mayerle, Julia; Schmid, Roland M.; Kuster, Bernhard; Rad, Roland; Braun, Christian J.; Wirth, Matthias; Reichert, Maximilian; Saur, Dieter und Schneider, Guenter
(2022):
Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype.
In: Jci Insight, Bd. 7, Nr. 10, 151353
Krauss, Lukas; Urban, Bettina C.; Hastreiter, Sieglinde; Schneider, Carolin; Wenzel, Patrick; Hassan, Zonera; Wirth, Matthias; Lankes, Katharina; Terrasi, Andrea; Klement, Christine; Cernilogar, Filippo M.; Öllinger, Rupert; Andrade Krätzig, Niklas de; Engleitner, Thomas; Schmid, Roland M.; Steiger, Katja; Rad, Roland; Krämer, Oliver H.; Reichert, Maximilian; Schotta, Gunnar; Saur, Dieter und Schneider, Günter
(2022):
HDAC2 Facilitates Pancreatic Cancer Metastasis.
In: Cancer Research, Bd. 82, Nr. 4: S. 695-707
Falcomata, Chiara; Baerthel, Stefanie; Widholz, Sebastian A.; Schneeweis, Christian; Montero, Juan Jose; Toska, Albulena; Mir, Jonas; Kaltenbacher, Thorsten; Heetmeyer, Jeannine; Swietlik, Jonathan J.; Cheng, Jing-Yuan; Teodorescu, Bianca; Reichert, Oliver; Schmitt, Constantin; Grabichler, Kathrin; Coluccio, Andrea; Boniolo, Fabio; Veltkamp, Christian; Zukowska, Magdalena; Vargas, Angelica Arenas; Paik, Woo Hyun; Jesinghaus, Moritz; Steiger, Katja; Maresch, Roman; Oellinger, Rupert; Ammon, Tim; Baranov, Olga; Robles, Maria S.; Rechenberger, Julia; Kuster, Bernhard; Meissner, Felix; Reichert, Maximilian; Flossdorf, Michael; Rad, Roland; Schmidt-Supprian, Marc; Schneider, Guenter und Saur, Dieter
(2022):
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment.
In: Nature Cancer, Bd. 3, Nr. 3: S. 318-336
Kaltenbacher, Thorsten; Löprich, Jessica; Maresch, Roman; Weber, Julia; Müller, Sebastian; Oellinger, Rupert; Gross, Nina; Griger, Joscha; Andrade Krätzig, Niklas de; Avramopoulos, Petros; Ramanujam, Deepak; Brummer, Sabine; Widholz, Sebastian A.; Bärthel, Stefanie; Falcomata, Chiara; Pfaus, Anja; Alnatsha, Ahmed; Mayerle, Julia; Schmidt-Supprian, Marc; Reichert, Maximilian; Schneider, Günter; Ehmer, Ursula; Braun, Christian J.; Saur, Dieter; Engelhardt, Stefan und Rad, Roland
(2022):
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver.
In: Nature Protocols, Bd. 17, Nr. 4: S. 1142-1188
Braun, Christian J.; Adames, Andres Carbonell; Saur, Dieter und Rad, Roland
(2022):
Tutorial: design and execution of CRISPR in vivo screens.
In: Nature Protocols, Bd. 17, Nr. 9: S. 1903-1925
Loevenich, Leon P.; Tschurtschenthaler, Markus; Rokavec, Matjaz; Silva, Miguel G.; Jesinghaus, Moritz; Kirchner, Thomas; Klauschen, Frederick; Saur, Dieter; Neumann, Jens; Hermeking, Heiko und Jung, Peter
(2022):
SMAD4 Loss Induces c-MYC-Mediated NLE1 Upregulation to Support Protein Biosynthesis, Colorectal Cancer Growth, and Metastasis.
In: Cancer Research, Bd. 82, Nr. 24: S. 4604-4623
Kalla, Daniela; Flisikowski, Krzysztof; Yang, Kaiyuan; Sanguesa, Laura Beltran; Kurome, Mayuko; Kessler, Barbara; Zakhartchenko, Valeri; Wolf, Eckhard; Lickert, Heiko; Saur, Dieter; Schnieke, Angelika und Flisikowska, Tatiana
(8. Oktober 2021):
The Missing Link: Cre Pigs for Cancer Research.
In: Frontiers in Oncology, Bd. 11, 755746
[PDF, 7MB]
Jesinghaus, Moritz; Schmitt, Maxime; Lang, Corinna; Reiser, Marianne; Scheiter, Alexander; Konukiewitz, Bjoern; Steiger, Katja; Silva, Miguel; Tschurtschenthaler, Markus; Lange, Sebastian; Foersch, Sebastian; Becker, Karl F.; Saur, Dieter; Friess, Helmut; Halfter, Kathrin; Engel, Jutta; Boxberg, Melanie; Pfarr, Nicole; Wilhelm, Dirk und Weichert, Wilko
(2021):
Morphology Matters A Critical Reappraisal of the Clinical Relevance of Morphologic Criteria From the 2019 WHO Classification in a Large Colorectal Cancer Cohort Comprising 1004 Cases.
In: American Journal of Surgical Pathology, Bd. 45, Nr. 7: S. 969-978
Volmar, Marie N. M.; Cheng, Jiying; Alenezi, Haitham; Richter, Sven; Haug, Alisha; Hassan, Zonera; Goldberg, Maria; Li, Yuping; Hou, Mengzhuo; Herold-Mende, Christel; Maire, Cecile L.; Lamszus, Katrin; Flueh, Charlotte; Held-Feindt, Janka; Gargiulo, Gaetano; Topping, Geoffrey J.; Schilling, Franz; Saur, Dieter; Schneider, Gunter; Synowitz, Michael; Schick, Joel A.; Kalin, Roland E. und Glass, Rainer
(2021):
Cannabidiol converts NF-kappa B into a tumor suppressor in glioblastoma with defined antioxidative properties.
In: Neuro-Oncology, Bd. 23, Nr. 11: S. 1898-1910
Boniolo, Fabio; Dorigatti, Emilio; Ohnmacht, Alexander J.; Saur, Dieter; Schubert, Benjamin und Menden, Michael P.
(2021):
Artificial intelligence in early drug discovery enabling precision medicine.
In: Expert Opinion on Drug Discovery, Bd. 16, Nr. 9: S. 991-1007
Jesinghaus, Moritz; Schmitt, Maxime; Lang, Corinna; Reiser, Marianne; Scheiter, Alexander; Konukiewitz, Björn; Steiger, Katja; Silva, Miguel; Tschurtschenthaler, Markus; Lange, Sebastian; Foersch, Sebastian; Becker, Karl F.; Saur, Dieter; Friess, Helmut; Halfter, Kathrin; Engel, Jutta; Boxberg, Melanie; Pfarr, Nicole; Wilhelm, Dirk und Weichert, Wilko
(2021):
Morphology Matters: A Critical Reappraisal of the Clinical Relevance of Morphologic Criteria From the 2019 WHO Classification in a Large Colorectal Cancer Cohort Comprising 1004 Cases.
In: The American Journal of Surgical Pathology, Bd. 45, Nr. 7: S. 969-978
Weber, Julia; Braun, Christian J.; Saur, Dieter und Rad, Roland
(2020):
In vivo functional screening for systems-level integrative cancer genomics.
In: Nature Reviews Cancer, Bd. 20, Nr. 10: S. 573-593
Müller, Sebastian; Lange, Sebastian; Collins, Katharina A. N.; Krebs, Stefan; Blum, Helmut; Schneider, Guenter; Rad, Lena; Saur, Dieter und Rad, Roland
(2020):
Linkage of genetic drivers and strain-specific germline variants confound mouse cancer genome analyses.
In: Nature Communications, Bd. 11, Nr. 1, 4474
[PDF, 921kB]
Pan, Chenchen; Schoppe, Oliver; Parra-Damas, Arnaldo; Cai, Ruiyao; Todorov, Mihail Ivilinov; Gondi, Gabor; Neubeck, Bettina von; Boeguercue-Seidel, Nuray; Seidel, Sascha; Sleiman, Katia; Veltkamp, Christian; Foerstera, Benjamin; Mai, Hongcheng; Rong, Zhouyi; Trompak, Omelyan; Ghasemigharagoz, Alireza; Reimer, Madita Alice; Cuesta, Angel M.; Coronel, Javier; Jeremias, Irmela; Saur, Dieter; Acker-Palmer, Amparo; Acker, Till; Garvalov, Boyan K.; Menze, Björn; Zeidler, Reinhard und Ertuerk, Ali
(2019):
Deep Learning Reveals Cancer Metastasis and Therapeutic Antibody Targeting in the Entire Body.
In: Cell, Bd. 179, Nr. 7
[PDF, 1MB]
Cheung, Phyllis F.; Neff, Florian; Neander, Christian; Bazarna, Anna; Savvatakis, Konstantinos; Liffers, Sven-Thorsten; Althoff, Kristina; Lee, Chang-Lung; Moding, Everett J.; Kirsch, David G.; Saur, Dieter; Bazhin, Alexandr V.; Trajkovic-Arsic, Marija; Heikenwalder, Mathias F. und Siveke, Jens T.
(2018):
Notch-Induced Myeloid Reprogramming in Spontaneous Pancreatic Ductal Adenocarcinoma by Dual Genetic Targeting.
In: Cancer Research, Bd. 78, Nr. 17: S. 4997-5010
Maresch, Roman; Mueller, Sebastian; Veltkamp, Christian; Öllinger, Rupert; Friedrich, Mathias; Heid, Irina; Steiger, Katja; Weber, Julia; Engleitner, Thomas; Barenboim, Maxim; Klein, Sabine; Louzada, Sandra; Banerjee, Ruby; Strong, Alexander; Stauber, Teresa; Gross, Nina; Geumann, Ulf; Lange, Sebastian; Ringelhan, Marc; Varela, Ignacio; Unger, Kristian; Yang, Fengtang; Schmid, Roland M.; Vassiliou, George S.; Braren, Rickmer; Schneider, Günter; Heikenwalder, Mathias; Bradley, Allan; Saur, Dieter und Rad, Roland
(2016):
Multiplexed pancreatic genome engineering and cancer induction by transfection-based CRISPR/Cas9 delivery in mice.
In: Nature Communications, Bd. 7, 10770
[PDF, 2MB]
Li, Shun; Flisikowska, Tatiana; Kurome, Mayuko; Zakhartchenko, Valeri; Kessler, Barbara; Saur, Dieter; Kind, Alexander; Wolf, Eckhard; Flisikowski, Krzysztof und Schnieke, Angelika
(2014):
Dual Fluorescent Reporter Pig for Cre Recombination: Transgene Placement at the ROSA26 Locus.
In: PLOS ONE 9(7), e102455 [PDF, 960kB]
In: PLOS ONE 9(7), e102455 [PDF, 960kB]
Heger, Klaus; Fierens, Kaat; Vahl, J. Christoph; Aszodi, Attila; Peschke, Katrin; Schenten, Dominik; Hammad, Hamida; Beyaert, Rudi; Saur, Dieter; Loo, Geert van; Roers, Axel; Lambrecht, Bart N.; Kool, Mirjam und Schmidt-Supprian, Marc
(2014):
A20-Deficient Mast Cells Exacerbate Inflammatory Responses In Vivo.
In: PLOS Biology 12(1), e1001762 [PDF, 2MB]
In: PLOS Biology 12(1), e1001762 [PDF, 2MB]