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Anzahl der Publikationen: 12
Zeitschriftenartikel
Nitsche, Valentin; Höfner, Georg; Kaiser, Jesko; Gertzen, Christoph G.W.; Seeger, Thomas; Niessen, Karin V.; Steinritz, Dirk; Worek, Franz; Gohlke, Holger; Paintner, Franz F. und Wanner, Klaus T. 
ORCID: https://orcid.org/0000-0003-4399-1425
(2024):
MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 392: S. 94-106
[PDF, 4MB]
ORCID: https://orcid.org/0000-0003-4399-1425
(2024):
MS Binding Assays with UNC0642 as reporter ligand for the MB327 binding site of the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 392: S. 94-106
[PDF, 4MB]
Bernauer, Tamara; Nitsche, Valentin; Kaiser, Jesko; Gertzen, Christoph G.W.; Höfner, Georg ORCID: https://orcid.org/0000-0002-7957-4503; Niessen, Karin V.; Seeger, Thomas; Steinritz, Dirk; Worek, Franz; Gohlke, Holger; Wanner, Klaus T. ORCID: https://orcid.org/0000-0003-4399-1425 und Paintner, Franz F.
(2024):
Synthesis and biological evaluation of novel MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after intoxication with nerve agents.
In: Toxicology Letters, Bd. 397: S. 151-162
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-7957-4503; Niessen, Karin V.; Seeger, Thomas; Steinritz, Dirk; Worek, Franz; Gohlke, Holger; Wanner, Klaus T. ORCID: https://orcid.org/0000-0003-4399-1425 und Paintner, Franz F.
(2024):
Synthesis and biological evaluation of novel MB327 analogs as resensitizers for desensitized nicotinic acetylcholine receptors after intoxication with nerve agents.
In: Toxicology Letters, Bd. 397: S. 151-162
[PDF, 2MB]
Sichler, Sonja; Höfner, Georg ORCID: https://orcid.org/0000-0002-7957-4503; Nitsche, Valentin; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Paintner, Franz F. und Wanner, Klaus T. ORCID: https://orcid.org/0000-0003-4399-1425
(2024):
Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 394: S. 23-31
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-7957-4503; Nitsche, Valentin; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Paintner, Franz F. und Wanner, Klaus T. ORCID: https://orcid.org/0000-0003-4399-1425
(2024):
Screening for new ligands of the MB327-PAM-1 binding site of the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 394: S. 23-31
[PDF, 2MB]
Kaiser, Jesko; Gertzen, Christoph G. W.; Bernauer, Tamara; Hoefner, Georg; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Wanner, Klaus T.; Worek, Franz; Thiermann, Horst und Gohlke, Holger
(2022):
A novel binding site in the nicotinic acetylcholine receptor for MB327 can explain its allosteric modulation relevant for organophosphorus-poisoning treatment.
In: Toxicology Letters, Bd. 373: S. 160-171
Wein, Thomas; Wanner, Klaus T.; Rappenglueck, Sebastian; Sichler, Sonja; Niessen, Karin; Seeger, Thomas; Worek, Franz und Thiermann, Horst
(2019):
New Resensitizers for the Nicotinic Acetylcholine Receptor by Ligand-Based Pharmacophore Modeling.
In: Current Computer-Aided Drug Design, Bd. 15, Nr. 1: S. 104-109
Popp, Tanja; Lueling, Robin; Boekhoff, Ingrid; Seeger, Thomas; Branoner, Francisco; Gudermann, Thomas; Thiermann, Horst; Worek, Franz und Steinritz, Dirk
(2018):
Immediate responses of the cockroach Blaptica dubia after the exposure to sulfur mustard.
In: Archives of Toxicology, Bd. 92, Nr. 1: S. 337-346
Scheffel, Corinna; Niessen, Karin V.; Rappenglück, Sebastian; Wanner, Klaus T.; Thiermann, Horst; Worek, Franz und Seeger, Thomas
(2018):
Counteracting desensitization of human alpha 7-nicotinic acetylcholine receptors with bispyridinium compounds as an approach against organophosphorus poisoning.
In: Toxicology Letters, Bd. 293: S. 149-156
Scheffel, Corinna; Niessen, Karin V.; Rappenglück, Sebastian; Wanner, Klaus. T.; Thiermann, Horst; Worek, Franz und Seeger, Thomas
(2018):
Electrophysiological investigation of the effect of structurally different bispyridinium non-oxime compounds on human alpha 7-nicotinic acetylcholine receptor activity-An in vitro structure-activity analysis.
In: Toxicology Letters, Bd. 293: S. 157-166
Wein, Thomas; Höfner, Georg; Rappenglück, Sebastian; Sichler, Sonja; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2018):
Searching for putative binding sites of the bispyridinium compound MB327 in the nicotinic acetylcholine receptor.
In: Toxicology Letters, Bd. 293: S. 184-189
Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2018):
Synthesis of a Series of Non-Symmetric Bispyridinium and Related Compounds and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor.
In: Chemmedchem, Bd. 13, Nr. 24: S. 2653-2663
Rappenglück, Sebastian; Sichler, Sonja; Höfner, Georg; Wein, Thomas; Niessen, Karin V.; Seeger, Thomas; Paintner, Franz F.; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2018):
Synthesis of a Series of Structurally Diverse MB327 Derivatives and Their Affinity Characterization at the Nicotinic Acetylcholine Receptor.
In: Chemmedchem, Bd. 13, Nr. 17: S. 1806-1816
Rappenglück, Sebastian; Niessen, Karin V.; Seeger, Thomas; Worek, Franz; Thiermann, Horst und Wanner, Klaus T.
(2017):
Regioselective and Transition-Metal-Free Addition of tert-Butyl Magnesium Reagents to Pyridine Derivatives: A Convenient Method for the Synthesis of 3-Substituted 4-tert-Butylpyridine Derivatives.
In: Synthesis-Stuttgart, Bd. 49, Nr. 17: S. 4055-4064