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Anzahl der Publikationen: 50

Zeitschriftenartikel

Koupourtidou, Christina ORCID logoORCID: https://orcid.org/0000-0002-8352-1498; Schwarz, Veronika; Aliee, Hananeh; Frerich, Simon ORCID logoORCID: https://orcid.org/0000-0002-8275-6113; Fischer-Sternjak, Judith; Bocchi, Riccardo ORCID logoORCID: https://orcid.org/0000-0002-4105-6807; Simon-Ebert, Tatiana; Bai, Xianshu ORCID logoORCID: https://orcid.org/0000-0002-4758-1645; Sirko, Swetlana ORCID logoORCID: https://orcid.org/0000-0001-5950-616X; Kirchhoff, Frank ORCID logoORCID: https://orcid.org/0000-0002-2324-2761; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X; Götz, Magdalena ORCID logoORCID: https://orcid.org/0000-0003-1551-9203; Theis, Fabian J. ORCID logoORCID: https://orcid.org/0000-0002-2419-1943 und Ninkovic, Jovica ORCID logoORCID: https://orcid.org/0000-0002-4381-0041 (2024): Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex. In: Nature Communications, Bd. 15, Nr. 1, 2866 [PDF, 57MB]

Schmidt, Sebastian; Stautner, Constantin; Vu, Duc Tung; Heinz, Alexander; Regensburger, Martin; Karayel, Ozge; Truembach, Dietrich; Artati, Anna; Kaltenhaeuser, Sabine; Nassef, Mohamed Zakaria; Hembach, Sina; Steinert, Letyfee; Winner, Beate; Juergen, Winkler; Jastroch, Martin; Luecken, Malte D.; Theis, Fabian J.; Westmeyer, Gil Gregor; Adamski, Jerzy; Mann, Matthias; Hiller, Karsten; Giesert, Florian; Weisenhorn, Daniela M. Vogt und Wurst, Wolfgang (2023): A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease. In: Nature Communications, Bd. 14, Nr. 1, 7674 [PDF, 7MB]

Kolabas, Zeynep Ilgin; Kuemmerle, Louis B.; Perneczky, Robert; Förstera, Benjamin; Ulukaya, Selin; Ali, Mayar; Kapoor, Saketh; Bartos, Laura M.; Büttner, Maren; Caliskan, Ozum Sehnaz; Rong, Zhouyi; Mai, Hongcheng; Höher, Luciano; Jeridi, Denise; Molbay, Muge; Khalin, Igor; Deligiannis, Ioannis K.; Negwer, Moritz; Roberts, Kenny; Simats, Alba; Carofiglio, Olga; Todorov, Mihail I.; Horvath, Izabela; Ozturk, Furkan; Hummel, Selina; Biechele, Gloria; Zatcepin, Artem; Unterrainer, Marcus; Gnörich, Johannes; Roodselaar, Jay; Shrouder, Joshua; Khosravani, Pardis; Tast, Benjamin; Richter, Lisa; Díaz-Marugán, Laura; Kaltenecker, Doris; Lux, Laurin; Chen, Ying; Zhao, Shan; Rauchmann, Boris-Stephan; Sterr, Michael; Kunze, Ines; Stanic, Karen; Kan, Vanessa W.Y.; Besson-Girard, Simon; Katzdobler, Sabrina; Palleis, Carla; Schädler, Julia; Paetzold, Johannes C.; Liebscher, Sabine; Hauser, Anja E.; Gokce, Ozgun; Lickert, Heiko; Steinke, Hanno; Benakis, Corinne; Braun, Christian; Martinez-Jimenez, Celia P.; Buerger, Katharina; Albert, Nathalie L.; Höglinger, Günter; Levin, Johannes; Haass, Christian; Kopczak, Anna; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X; Havla, Joachim ORCID logoORCID: https://orcid.org/0000-0002-4386-1340; Kümpfel, Tania; Kerschensteiner, Martin; Schifferer, Martina; Simons, Mikael; Liesz, Arthur ORCID logoORCID: https://orcid.org/0000-0002-9069-2594; Krahmer, Natalie; Bayraktar, Omer A.; Franzmeier, Nicolai ORCID logoORCID: https://orcid.org/0000-0001-9736-2283; Plesnila, Nikolaus; Erener, Suheda; Puelles, Victor G.; Delbridge, Claire; Bhatia, Harsharan Singh; Hellal, Farida; Elsner, Markus; Bechmann, Ingo; Ondruschka, Benjamin; Brendel, Matthias; Theis, Fabian J. und Erturk, Ali (2023): Distinct molecular profiles of skull bone marrow in health and neurological disorders. In: Cell, Bd. 186, Nr. 17, 3706-3725.e29 [PDF, 19MB]

Lutz, Konstantin; Musumeci, Andrea; Sie, Christopher; Dursun, Ezgi; Winheim, Elena; Bagnoli, Johannes; Ziegenhain, Christoph; Rausch, Lisa; Bergen, Volker; Luecken, Malte D.; Oostendorp, Robert A. J.; Schraml, Barbara U.; Theis, Fabian J.; Enard, Wolfgang; Korn, Thomas und Krug, Anne B. (16. Juni 2022): Ly6D+Siglec-H+ precursors contribute to conventional dendritic cells via a Zbtb46+Ly6D+ intermediary stage. In: Nature Communications, Bd. 13 [PDF, 7MB]

Hersbach, Bob A. ORCID logoORCID: https://orcid.org/0000-0001-9995-1364; Fischer, David S. ORCID logoORCID: https://orcid.org/0000-0002-1293-7656; Masserdotti, Giacomo; Deeksha, Deeksha; Mojžišová, Karolina; Waltzhöni, Thomas; Rodriguez‐Terrones, Diego; Heinig, Matthias; Theis, Fabian J. ORCID logoORCID: https://orcid.org/0000-0002-2419-1943; Götz, Magdalena ORCID logoORCID: https://orcid.org/0000-0003-1551-9203 und Stricker, Stefan H. ORCID logoORCID: https://orcid.org/0000-0002-5488-8530 (2022): Probing cell identity hierarchies by fate titration and collision during direct reprogramming. In: Molecular Systems Biology, Bd. 18, e11129 [PDF, 4MB]

Hawe, Johann S.; Saha, Ashis; Waldenberger, Melanie; Kunze, Sonja; Wahl, Simone; Müller-Nurasyid, Martina ORCID logoORCID: https://orcid.org/0000-0003-3793-5910; Prokisch, Holger; Grallert, Harald; Herder, Christian; Peters, Annette ORCID logoORCID: https://orcid.org/0000-0001-6645-0985; Strauch, Konstantin; Theis, Fabian J.; Gieger, Christian; Chambers, John; Battle, Alexis und Heinig, Matthias ORCID logoORCID: https://orcid.org/0000-0002-5612-1720 (2022): Network reconstruction for trans acting genetic loci using multi-omics data and prior information. In: Genome Medicine, Bd. 14, 125 [PDF, 3MB]

Schmidt, Sebastian; Luecken, Malte D.; Truembach, Dietrich; Hembach, Sina; Niedermeier, Kristina M.; Wenck, Nicole; Pfluegler, Klaus; Stautner, Constantin; Boettcher, Anika; Lickert, Heiko; Ramirez-Suastegui, Ciro; Ahmad, Ruhel; Ziller, Michael J.; Fitzgerald, Julia C.; Ruf, Viktoria; Berg, Wilma D. J. van de; Jonker, Allert J.; Gasser, Thomas; Winner, Beate; Winkler, Juergen; Weisenhorn, Daniela M. Vogt; Giesert, Florian; Theis, Fabian J. und Wurst, Wolfgang (2022): Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease. In: Nature Communications, Bd. 13, Nr. 1, 4819 [PDF, 5MB]

Giehrl-Schwab, Jessica; Giesert, Florian; Rauser, Benedict; Lao, Chu Lan; Hembach, Sina; Lefort, Sandrine; Ibarra, Ignacio L.; Koupourtidou, Christina; Luecken, Malte Daniel; Truong, Dong-Jiunn Jeffery; Fischer-Sternjak, Judith; Masserdotti, Giacomo; Prakash, Nilima; Ninkovic, Jovica; Hoelter, Sabine M.; Weisenhorn, Daniela M. Vogt; Theis, Fabian J.; Goetz, Magdalena und Wurst, Wolfgang (2022): Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons. In: EMBO Molecular Medicine, Bd. 14, Nr. 5, e14797 [PDF, 3MB]

Falkai, Peter; Koutsouleris, Nikolaos; Bertsch, Katja; Bialas, Mirko; Binder, Elisabeth; Buehner, Markus; Buyx, Alena; Cai, Na; Cappello, Silvia; Ehring, Thomas; Gensichen, Jochen; Hamann, Johannes; Hasan, Alkomiet; Henningsen, Peter; Leucht, Stefan; Moehrmann, Karl Heinz; Nagelstutz, Elisabeth; Padberg, Frank; Peters, Annette; Pfaeffel, Lea; Reich-Erkelenz, Daniela; Riedl, Valentin; Rueckert, Daniel; Schmitt, Andrea; Schulte-Koerne, Gerd; Scheuring, Elfriede; Schulze, Thomas G.; Starzengruber, Rudolf; Stier, Susanne; Theis, Fabian J.; Winkelmann, Juliane; Wurst, Wolfgang und Priller, Josef (2022): Concept of the Munich/Augsburg Consortium Precision in Mental Health for the German Center of Mental Health. In: Frontiers in Psychiatry, Bd. 13, 815718

Benakis, Corinne; Simats, Alba; Tritschler, Sophie; Heindl, Steffanie; Besson-Girard, Simon; Llovera, Gemma; Pinkham, Kelsey; Kolz, Anna; Ricci, Alessio; Theis, Fabian J.; Bittner, Stefan; Goekce, Oezguen; Peters, Anneli und Liesz, Arthur (2022): T cells modulate the microglial response to brain ischemia. In: eLife, Bd. 11, e82031 [PDF, 2MB]

Tritschler, Sophie; Thomas, Moritz; Boettcher, Anika; Ludwig, Barbara; Schmid, Janine; Schubert, Undine; Kemter, Elisabeth; Wolf, Eckhard; Lickert, Heiko und Theis, Fabian J. (2022): A transcriptional cross species map of pancreatic islet cells. In: Molecular Metabolism, Bd. 66, 101595

Reichart, Daniel; Lindberg, Eric L.; Maatz, Henrike; Miranda, Antonio M. A.; Viveiros, Anissa; Shvetsov, Nikolay; Gaertner, Anna; Nadelmann, Emily R.; Lee, Michael; Kanemaru, Kazumasa; Ruiz-Orera, Jorge; Strohmenger, Viktoria; DeLaughter, Daniel M.; Patone, Giannino; Zhang, Hao; Woehler, Andrew; Lippert, Christoph; Kim, Yuri; Adami, Eleonora; Gorham, Joshua M.; Barnett, Sam N.; Brown, Kemar; Buchan, Rachel J.; Chowdhury, Rasheda A.; Constantinou, Chrystalla; Cranley, James; Felkin, Leanne E.; Fox, Henrik; Ghauri, Ahla; Gummert, Jan; Kanda, Masatoshi; Li, Ruoyan; Mach, Lukas; McDonough, Barbara; Samari, Sara; Shahriaran, Farnoush; Yapp, Clarence; Stanasiuk, Caroline; Theotokis, Pantazis I.; Theis, Fabian J.; Bogaerdt, Antoon van der; Wakimoto, Hiroko; Ware, James S.; Worth, Catherine L.; Barton, Paul J. R.; Lee, Young-Ae; Teichmann, Sarah A.; Milting, Hendrik; Noseda, Michela; Oudit, Gavin Y.; Heinig, Matthias; Seidman, Jonathan G.; Hubner, Norbert und Seidman, Christine E. (2022): Pathogenic variants damage cell composition and single-cell transcription in cardiomyopathies. In: Science, Bd. 377, Nr. 6606, eabo1984

Fischer, David S.; Ansari, Meshal; Wagner, Karolin I.; Jarosch, Sebastian; Huang, Yiqi; Mayr, Christoph H.; Strunz, Maximilian; Lang, Niklas J.; D'Ippolito, Elvira; Hammel, Monika; Mateyka, Laura; Weber, Simone; Wolff, Lisa S.; Witter, Klaus; Fernandez, Isis E.; Leuschner, Gabriela; Milger, Katrin; Frankenberger, Marion; Nowak, Lorenz; Heinig-Menhard, Katharina; Koch, Ina; Stoleriu, Mircea G.; Hilgendorff, Anne; Behr, Jürgen; Pichlmair, Andreas; Schubert, Benjamin; Theis, Fabian J.; Busch, Dirk H.; Schiller, Herbert B. und Schober, Kilian (2021): Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'. In: Nature Communications, Bd. 12, Nr. 1, 4515

Boettcher, Anika; Buettner, Maren; Tritschler, Sophie; Sterr, Michael; Aliluev, Alexandra; Oppenlaender, Lena; Burtscher, Ingo; Sass, Steffen; Irmler, Martin; Beckers, Johannes; Ziegenhain, Christoph; Enard, Wolfgang; Schamberger, Andrea C.; Verhamme, Fien M.; Eickelberg, Oliver; Theis, Fabian J. und Lickert, Heiko (2021): Non-canonical Wnt/PCP signalling regulates intestinal stem cell lineage priming towards enteroendocrine and Paneth cell fates. In: Nature Cell Biology, Bd. 23, Nr. 1

Danese, Anna; Richter, Maria L.; Chaichoompu, Kridsadakorn; Fischer, David S.; Theis, Fabian J. und Colome-Tatche, Maria (2021): EpiScanpy: integrated single-cell epigenomic analysis. In: Nature Communications, Bd. 12, Nr. 1, 5228 [PDF, 2MB]

Lopez, Juan Pablo; Brivio, Elena; Santambrogio, Alice; De Donno, Carlo; Kos, Aron; Peters, Miriam; Rost, Nicolas; Czamara, Darina; Brueckl, Tanja M.; Roeh, Simone; Poehlmann, Max L.; Engelhardt, Clara; Ressle, Andrea; Stoffel, Rainer; Tontsch, Alina; Villamizar, Javier M.; Reincke, Martin; Riester, Anna; Sbiera, Silviu; Fassnacht, Martin; Mayberg, Helen S.; Craighead, W. Edward; Dunlop, Boadie W.; Nemeroff, Charles B.; Schmidt, Mathias V.; Binder, Elisabeth B.; Theis, Fabian J.; Beuschlein, Felix; Andoniadou, Cynthia L. und Chen, Alon (2021): Single-cell molecular profiling of all three components of the HPA axis reveals adrenal ABCB1 as a regulator of stress adaptation. In: Science Advances, Bd. 7, Nr. 5, eabe4497

Luecken, Malte D.; Buettner, M.; Chaichoompu, K.; Danese, A.; Interlandi, M.; Mueller, M. F.; Strobl, D. C.; Zappia, L.; Dugas, M.; Colome-Tatche, M. und Theis, Fabian J. (2021): Benchmarking atlas-level data integration in single-cell genomics. In: Nature Methods, Bd. 19, Nr. 1: S. 41-50

Mayr, Christoph H.; Simon, Lukas M.; Leuschner, Gabriela; Ansari, Meshal; Schniering, Janine; Geyer, Philipp E.; Angelidis, Ilias; Strunz, Maximilian; Singh, Pawandeep; Kneidinger, Nikolaus; Reichenberger, Frank; Silbernagel, Edith; Boehm, Stephan; Adler, Heiko; Lindner, Michael; Maurer, Britta; Hilgendorff, Anne; Prasse, Antje; Behr, Jürgen; Mann, Matthias; Eickelberg, Oliver; Theis, Fabian J. und Schiller, Herbert B. (2021): Integrative analysis of cell state changes in lung fibrosis with peripheral protein biomarkers. In: EMBO Molecular Medicine, Bd. 13, Nr. 4, e12871

Sachs, Stephan; Bastidas-Ponce, Aimee; Tritschler, Sophie; Bakhti, Mostafa; Böttcher, Anika; Sanchez-Garrido, Miguel A.; Tarquis-Medina, Marta; Kleinert, Maximilian; Fischer, Katrin; Jall, Sigrid; Harger, Alexandra; Bader, Erik; Roscioni, Sara; Ussar, Siegfried; Feuchtinger, Annette; Yesildag, Burcak; Neelakandhan, Aparna; Jensen, Christine B.; Cornu, Marion; Yang, Bin; Finan, Brian; DiMarchi, Richard D.; Tschöp, Matthias H.; Theis, Fabian J.; Hofmann, Susanna M.; Müller, Timo D. und Lickert, Heiko (2020): Targeted pharmacological therapy restores beta-cell function for diabetes remission. In: Nature Metabolism, Bd. 2, Nr. 2: S. 192-209

Rajewsky, Nikolaus; Almouzni, Genevieve; Gorski, Stanislaw A.; Aerts, Stein; Amit, Ido; Bertero, Michela G.; Bock, Christoph; Bredenoord, Annelien L.; Cavalli, Giacomo; Chiocca, Susanna; Clevers, Hans; De Strooper, Bart; Eggert, Angelika; Ellenberg, Jan; Fernandez, Xose M.; Figlerowicz, Marek; Gasser, Susan M.; Hubner, Norbert; Kjems, Jorgen; Knoblich, Jürgen A.; Krabbe, Grietje; Lichter, Peter; Linnarsson, Sten; Marine, Jean-Christophe; Marioni, John C.; Marti-Renom, Marc A.; Netea, Mihai G.; Nickel, Dorthe; Nollmann, Marcelo; Novak, Halina R.; Parkinson, Helen; Piccolo, Stefano; Pinheiro, Ines; Pombo, Ana; Popp, Christian; Reik, Wolf; Roman-Roman, Sergio; Rosenstiel, Philip; Schultze, Joachim L.; Stegle, Oliver; Tanay, Amos; Testa, Giuseppe; Thanos, Dimitris; Theis, Fabian J.; Torres-Padilla, Maria-Elena; Valencia, Alfonso; Vallot, Celine; van Oudenaarden, Alexander; Vidal, Marie und Voet, Thierry (2020): LifeTime and improving European healthcare through cell-based interceptive medicine. In: Nature, Bd. 587, Nr. 7834: S. 377-386

Kozak, Eva L.; Palit, Subarna; Miranda-Rodriguez, Jeronimo R.; Janjic, Aleksandar; Böttcher, Anika; Lickert, Heiko; Enard, Wolfgang; Theis, Fabian J. und Lopez-Schier, Hernan (2020): Epithelial Planar Bipolarity Emerges from Notch-Mediated Asymmetric Inhibition of Emx2. In: Current Biology, Bd. 30, Nr. 6: S. 1142-1151

Chlis, Nikolaos-Kosmas; Rausch, Lisa; Brocker, Thomas; Kranich, Jan und Theis, Fabian J. (2020): Predicting single-cell gene expression profiles of imaging flow cytometry data with machine learning. In: Nucleic Acids Research, Bd. 48, Nr. 20: S. 11335-11346

Kranich, Jan; Chlis, Nikolaos-Kosmas; Rausch, Lisa; Latha, Ashretha; Schifferer, Martina; Kurz, Tilman; Kia, Agnieszka Foltyn-Arfa; Simons, Mikael; Theis, Fabian J. und Brocker, Thomas (2020): In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning. In: Journal of Extracellular Vesicles, Bd. 9, Nr. 1, 1792683 [PDF, 3MB]

Holmberg, Olle G.; Kohler, Niklas D.; Martins, Thiago; Siedlecki, Jakob; Herold, Tina; Keidel, Leonie; Asani, Ben; Schiefelbein, Johannes; Priglinger, Siegfried; Kortuem, Karsten U. und Theis, Fabian J. (2020): Self-supervised retinal thickness prediction enables deep learning from unlabelled data to boost classification of diabetic retinopathy. In: Nature Machine Intelligence, Bd. 2, Nr. 11: S. 719-726

Strunz, Maximilian; Simon, Lukas M.; Ansari, Meshal; Kathiriya, Jaymin J.; Angelidis, Ilias; Mayr, Christoph H.; Tsidiridis, George; Lange, Marius; Mattner, Laura F.; Yee, Min; Ogar, Paulina; Sengupta, Arunima; Kukhtevich, Igor; Schneider, Robert; Zhao, Zhongming; Voss, Carola; Stoeger, Tobias; Neumann, Jens H. L.; Hilgendorff, Anne; Behr, Jürgen; O'Reilly, Michael; Lehmann, Mareike; Burgstaller, Gerald; Königshoff, Melanie; Chapman, Harold A.; Theis, Fabian J. und Schiller, Herbert B. (2020): Alveolar regeneration through a Krt8+transitional stem cell state that persists in human lung fibrosis. In: Nature Communications, Bd. 11, Nr. 1, 3559 [PDF, 11MB]

Arloth, Janine; Eraslan, Gökcen; Rietschel, Marcella; Theis, Fabian J.; Binder, Elisabeth B.; Müller, Nikola S. und Strauch, Konstantin (2020): DeepWAS: Multivariate genotype-phenotype associations by directly integrating regulatory information using deep learning.
In: PLoS computational biology 16(2), e1007616 [PDF, 3MB]

Czamara, Darina; Eraslan, Goekcen; Page, Christian M.; Lahti, Jari; Lahti-Pulkkinen, Marius; Hamalainen, Esa; Kajantie, Eero; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Nystad, Wenche; Haberg, Siri E.; London, Stephanie J.; O'Donnell, Kieran J.; Garg, Elika; Meaney, Michael J.; Entringer, Sonja; Wadhwa, Pathik D.; Buss, Claudia; Jones, Meaghan J.; Lin, David T. S.; MacIsaac, Julie L.; Kobor, Michael S.; Koen, Nastassja; Zar, Heather J.; Koenen, Karestan C.; Dalvie, Shareefa; Stein, Dan J.; Kondofersky, Ivan; Müller, Nikola S.; Theis, Fabian J.; Raikkonen, Katri; Binder, Elisabeth B.; Wray, Naomi R.; Ripke, Stephan; Mattheisen, Manuel; Trzaskowski, Maciej; Byrne, Enda M.; Abdellaoui, Abdel; Adams, Mark J.; Agerbo, Esben; Air, Tracy M.; Andlauer, Till F. M.; Bacanu, Silviu-Alin; Baekvad-Hansen, Marie; Beekman, Aartjan T. F.; Bigdeli, Tim B.; Blackwood, Douglas H. R.; Bryois, Julien; Buttenschon, Henriette N.; Bybjerg-Grauholm, Jonas; Cai, Na; Castelao, Enrique; Christensen, Jane Hvarregaard; Clarke, Toni-Kim; Coleman, Jonathan R.; Colodro-Conde, Lucia; Couvy-Duchesne, Baptiste; Craddock, Nick; Crawford, Gregory E.; Davies, Gail; Deary, Ian J.; Degenhardt, Franziska; Derks, Eske M.; Direk, Nese; Dolan, Conor; Dunn, Erin C.; Eley, Thalia C.; Escott-Price, Valentina; Kiadeh, Farnush Farhadi Hassan; Finucane, Hilary K.; Forstner, Andreas J.; Frank, Josef; Gaspar, Helena A.; Gill, Michael; Goes, Fernando S.; Gordon, Scott D.; Grove, Jakob; Hall, Lynsey S.; Hansen, Christine Soholm; Hansen, Thomas F.; Herms, Stefan; Hickie, Ian B.; Hoffmann, Per; Homuth, Georg; Horn, Carsten; Hottenga, Jouke-Jan; Hougaard, David M.; Ising, Marcus; Jansen, Rick; Jörgenson, Eric; Knowles, James A.; Kohane, Isaac S.; Kraft, Julia; Kretzschmar, Warren W.; Krogh, Jesper; Kutalik, Zoltan; Li, Yihan; Lind, Penelope A.; MacIntyre, Donald J.; MacKinnon, Dean F.; Maier, Robert M.; Maier, Wolfgang; Marchini, Jonathan; Mbarek, Hamdi; McGrath, Patrick; McGuffin, Peter; Medland, Sarah E.; Mehta, Divya; Middeldorp, Christel M.; Mihailov, Evelin; Milaneschi, Yuri; Milani, Lili; Mondimore, Francis M.; Montgomery, Grant W.; Mostafavi, Sara; Mullins, Niamh; Nauck, Matthias; Ng, Bernard; Nivard, Michel G.; Nyholt, Dale R.; O'Reilly, Paul F.; Oskarsson, Hogni; Owen, Michael J.; Painter, Jodie N.; Pedersen, Carsten Bocker; Pedersen, Marianne Girtz; Peterson, Roseann E.; Pettersson, Erik; Peyrot, Wouter J.; Pistis, Giorgio; Posthuma, Danielle; Quiroz, Jörge A.; Qvist, Per; Rice, John P.; Riley, Brien P.; Rivera, Margarita; Mirza, Saira Saeed; Schoevers, Robert; Schulte, Eva C.; Shen, Ling; Shi, Jianxin; Shyn, Stanley; Sigurdsson, Engilbert; Sinnamon, Grant C. B.; Smit, Johannes H.; Smith, Daniel J.; Stefansson, Hreinn; Steinberg, Stacy; Streit, Fabian; Strohmaier, Jana; Tansey, Katherine E.; Teismann, Henning; Teumer, Alexander; Thompson, Wesley; Thomson, Pippa A.; Thorgeirsson, Thorgeir E.; Traylor, Matthew; Treutlein, Jens; Trubetskoy, Vassily; Uitterlinden, Andre G.; Umbricht, Daniel; Van der Auwera, Sandra; van Hemert, Albert M.; Viktorin, Alexander; Visscher, Peter M.; Wang, Yunpeng; Webb, Bradley T.; Weinsheimer, Shantel Marie; Wellmann, Jürgen; Willemsen, Gonneke; Witt, Stephanie H.; Wu, Yang; Xi, Hualin S.; Yang, Jian; Zhang, Futao; Arolt, Volker; Baune, Bernhard T.; Berger, Klaus; Boomsma, Dorret; Cichon, Sven; Dannlowski, Udo; de Geus, E. J. C.; DePaulo, J. Raymond; Domenici, Enrico; Domschke, Katharina; Esko, Tonu; Grabe, Hans J.; Hamilton, Steven P.; Hayward, Caroline; Heath, Andrew C.; Kendler, Kenneth S.; Kloiber, Stefan; Lewis, Glyn; Li, Qingqin S.; Lucae, Susanne; Madden, Pamela A. F.; Magnusson, Patrik K.; Martin, Nicholas G.; McIntosh, Andrew M.; Metspalu, Andres; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Nordentoft, Merete; Noethen, Markus M.; O'Donovan, Michael C.; Paciga, Sara A.; Pedersen, Nancy L.; Penninx, Brenda W. J. H.; Perlis, Roy H.; Porteous, David J.; Potash, James B.; Preisig, Martin; Rietschel, Marcella; Schäfer, Catherine; Schulze, Thomas G.; Smoller, Jordan W.; Stefansson, Kari; Tiemeier, Henning; Uher, Rudolf; Voelzke, Henry; Weissman, Myrna M.; Werge, Thomas; Lewis, Cathryn M.; Levinson, Douglas F.; Breen, Gerome; Borglum, Anders D. und Sullivan, Patrick F. (2019): Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns. In: Nature Communications, Bd. 10, 2548 [PDF, 1MB]

Matejka, Kerstin; Stueckler, Ferdinand; Salomon, Michael; Ensenauer, Regina; Reischl, Eva; Hoerburger, Lena; Grallert, Harald; Kastenmüller, Gabi; Peters, Annette; Daniel, Hannelore; Krumsiek, Jan; Theis, Fabian J.; Hauner, Hans und Laumen, Helmut (2019): Dynamic modelling of an ACADS genotype in fatty acid oxidation - Application of cellular models for the analysis of common genetic variants.
In: PLOS One 14(5), e0216110 [PDF, 982kB]

Krautenbacher, Norbert; Flach, Nicolai; Böck, Andreas; Laubhahn, Kristina; Laimighofer, Michael; Theis, Fabian J.; Ankerst, Donna P.; Fuchs, Christiane und Schaub, Bianca (2019): A strategy for high-dimensional multivariable analysis classifies childhood asthma phenotypes from genetic, immunological, and environmental factors. In: Allergy, Bd. 74, Nr. 7: S. 1364-1373

Bast, Lisa; Calzolari, Filippo; Strasser, Michael K.; Hasenauer, Jan; Theis, Fabian J.; Ninkovic, Jovica und Marr, Carsten (2018): Increasing Neural Stem Cell Division Asymmetry and Quiescence Are Predicted to Contribute to the Age-Related Decline in Neurogenesis. In: Cell Reports, Bd. 25, Nr. 12: S. 3231-3240 [PDF, 5MB]

Do, Kieu Trinh; Wahl, Simone; Raffler, Johannes; Molnos, Sophie; Laimighofer, Michael; Adamski, Jerzy; Suhre, Karsten; Strauch, Konstantin; Peters, Annette; Gieger, Christian; Langenberg, Claudia; Stewart, Isobel D.; Theis, Fabian J.; Grallert, Harald; Kastenmüller, Gabi und Krumsiek, Jan (2018): Characterization of missing values in untargeted MS-based metabolomics data and evaluation of missing data handling strategies. In: Metabolomics, Bd. 14, Nr. 10, 128

Bartel, Sabine; Schulz, Nikola; Alessandrini, Francesca; Schamberger, Andrea C.; Pagel, Philipp; Theis, Fabian J.; Milger, Katrin; Nössner, Elfriede; Stick, Stephen M.; Kicic, Anthony; Eickelberg, Oliver; Freishtat, Robert J. und Krauss-Etschmann, Susanne (2017): ZUMA-4 preliminary results: phase 1 study of KTE-C19 chimeric antigen receptor T cell therapy in pediatric and adolescent patients (pts) with relapsed/refractory acute lymphoblastic leukemia (R/R ALL). In: Scientific Reports, Bd. 7, 46026 [PDF, 3MB]

Heilbronner, Urs; Jain, Gaurav; Kaurani, Lalit; Kondofersky, Ivan; Budde, Monika; Gade, Katrin; Kalman, Janos; Adorjan, Kristina; Aldinger, Fanny; Anderson-Schmidt, Heike; Müller, Nikola; Theis, Fabian J.; Falkai, Peter ORCID logoORCID: https://orcid.org/0000-0003-2873-8667; Fischer, Andre und Schulze, Thomas G. (2017): The Role of Micrornas in the Course Of Severe Mental Disorders. In: European Neuropsychopharmacology, Bd. 27: S456-S457

Budde, Monika; Kondofersky, Ivan; Adorjan, Kristina; Aldinger, Fanny; Anderson-Schmidt, Heike; Andlauer, Till F. M.; Flatau, Laura; Gade, Katrin; Heilbronner, Urs; Kalman, Janos; Papiol, Sergi; Theis, Fabian J.; Falkai, Peter ORCID logoORCID: https://orcid.org/0000-0003-2873-8667; Müller, Nikola S. und Schulze, Thomas G. (2017): Integrating Polygenic Allele Burden Information And Phenomic Data To Characterize Complex Disease Trajectories In Severe Mental Illness. In: European Neuropsychopharmacology, Bd. 27: S406-S406

Schulte, Eva; Kondofersky, Ivan; Budde, Monika; Adorjan, Kristina; Aldinger, Fanny; Anderson-Schmidt, Heike; Andlauer, Till F. M.; Gade, Katrin; Heilbronner, Urs; Kalman, Janos; Papiol, Sergi; Theis, Fabian J.; Falkai, Peter ORCID logoORCID: https://orcid.org/0000-0003-2873-8667; Müller, Nikola und Schulze, Thomas G. (2017): Polygenic Burden Analysis Of Longitudinal Clusters Of Psychopathological Features In A Cross-Diagnostic Group Of Individuals With Severe Mental Illness. In: European Neuropsychopharmacology, Bd. 27: S401-S402

Molnos, Sophie; Baumbach, Clemens; Wahl, Simone; Müller-Nurasyid, Martina; Strauch, Konstantin; Wang-Sattler, Rui; Waldenberger, Melanie; Meitinger, Thomas; Adamski, Jerzy; Kastenmüller, Gabi; Suhre, Karsten; Peters, Annette; Grallert, Harald; Theis, Fabian J. und Gieger, Christian (2017): pulver: an R package for parallel ultra-rapid p-value computation for linear regression interaction terms. In: BMC Bioinformatics 18:429 [PDF, 1MB]

Comes, Ashley; Aldinger, Fanny; Kondofersky, Ivan; Adorjan, Kristina; Anderson-Schmidt, Heike; Andlauer, Till F. M.; Budde, Monika; Gade, Katrin; Heilbronner, Urs; Kalman, Janos; Papiol, Sergi; Theis, Fabian J.; Falkai, Peter ORCID logoORCID: https://orcid.org/0000-0003-2873-8667; Müller, Nikola und Schulze, Thomas (2017): Polygenic Burden Analysis of Longitudinal Clusters of Quality Of Life and Functioning In Patients with Severe Mental Illness. In: European Neuropsychopharmacology, Bd. 27: S408-S409

Benedetti, Elisa; Pucic-Bakovic, Maja; Keser, Toma; Wahl, Annika; Hassinen, Antti; Yang, Jeong-Yeh; Liu, Lin; Trbojevic-Akmacic, Irena; Razdorov, Genadij; Stambuk, Jerko; Klaric, Lucija; Ugrina, Ivo; Selman, Maurice H. J.; Wuhrer, Manfred; Rudan, Igor; Polasek, Ozren; Hayward, Caroline; Grallert, Harald; Strauch, Konstantin; Peters, Annette; Meitinger, Thomas; Gieger, Christian; Vilaj, Marija; Boons, Geert-Jan; Moremen, Kelley W.; Ovchinnikova, Tatiana; Bovin, Nicolai; Kellokumpu, Sakari; Theis, Fabian J.; Lauc, Gordan und Krumsiek, Jan (2017): Network inference from glycoproteomics data reveals new reactions in the IgG glycosylation pathway. In: Nature Communications, Bd. 8, 1483 [PDF, 3MB]

Eulenberg, Philipp; Köhler, Niklas; Blasi, Thomas; Filby, Andrew; Carpenter, Anne E.; Rees, Paul; Theis, Fabian J. und Wolf, F. Alexander (2017): Reconstructing cell cycle and disease progression using deep learning. In: Nature Communications, Bd. 8, 463 [PDF, 1MB]

Fröhlich, Fabian; Theis, Fabian J.; Rädler, Joachim O. und Hasenauer, Jan (2017): Parameter estimation for dynamical systems with discrete events and logical operations. In: Bioinformatics, Bd. 33, Nr. 7: S. 1049-1056

Krendl, Christian; Shaposhnikov, Dmitry; Rishko, Valentyna; Ori, Chaido; Ziegenhain, Christoph; Sass, Steffen; Simon, Lukas; Müller, Nikola S.; Straub, Tobias; Brooks, Kelsey E.; Chavez, Shawn L.; Enard, Wolfgang; Theis, Fabian J. und Drukker, Micha (2017): GATA2/3-TFAP2A/C transcription factor network couples human pluripotent stem cell differentiation to trophectoderm with repression of pluripotency. In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 45, E9579-E9588

Conlon, Thomas M.; Bartel, Jörg; Ballweg, Korbinian; Günter, Stefanie; Prehn, Cornelia; Krumsiek, Jan; Meiners, Silke; Theis, Fabian J.; Adamski, Jerzy; Eickelberg, Oliver und Yildirim, Ali Önder (2016): Metabolomics screening identifies reduced L-carnitine to be associated with progressive emphysema. In: Clinical Science, Bd. 130, Nr. 4: S. 273-287

Blasi, Thomas; Feller, Christian; Feigelman, Justin; Hasenauer, Jan; Imhof, Axel; Theis, Fabian J.; Becker, Peter B. ORCID logoORCID: https://orcid.org/0000-0001-7186-0372 und Marr, Carsten (2016): Combinatorial Histone Acetylation Patterns Are Generated by Motif-Specific Reactions. In: Cell Systems, Bd. 2, Nr. 1: S. 49-58

Bartel, Jörg; Krumsiek, Jan; Schramm, Katharina; Adamski, Jerzy; Gieger, Christian; Herder, Christian; Carstensen, Maren; Peters, Annette; Rathmann, Wolfgang; Roden, Michael; Strauch, Konstantin; Suhre, Karsten; Kastenmueller, Gabi; Prokisch, Holger und Theis, Fabian J. (2015): The Human Blood Metabolome-Transcriptome Interface.
In: PLOS Genetics 11(6), e1005274 [PDF, 5MB]

Meyer, Swanhild U.; Sass, Steffen; Mueller, Nikola S.; Krebs, Stefan; Bauersachs, Stefan; Kaiser, Sebastian; Blum, Helmut; Thirion, Christian; Krause, Sabine; Theis, Fabian J. und Pfaffl, Michael W. (2015): Integrative Analysis of MicroRNA and mRNA Data Reveals an Orchestrated Function of MicroRNAs in Skeletal Myocyte Differentiation in Response to TNF-alpha or IGF1.
In: PLOS ONE 10(8), e0135284 [PDF, 3MB]

Jourdan, Carolin; Petersen, Ann-Kristin; Gieger, Christian; Döring, Angela; Illig, Thomas; Wang-Sattler, Rui; Meisinger, Christa; Peters, Annette; Adamski, Jerzy; Prehn, Cornelia; Suhre, Karsten; Altmaier, Elisabeth; Kastenmüller, Gabi; Römisch-Margl, Werner; Theis, Fabian J.; Krumsiek, Jan; Wichmann, Heinz-Erich und Linseisen, Jakob (2012): Body fat free mass is associated with the serum metabolite profile in a population-based study.
In: PLOS ONE 7(6), e40009 [PDF, 324kB]

Petersen, Ann-Kristin; Krumsiek, Jan; Waegele, Brigitte; Theis, Fabian J.; Wichmann, H-Erich; Gieger, Christian und Suhre, Karsten (2012): On the hypothesis-free testing of metabolite ratios in genome-wide and metabolome-wide association studies. In: BMC Bioinformatics 13:120 [PDF, 274kB]

Mittelstrass, Kirstin; Ried, Janina S.; Yu, Zhonghao; Krumsiek, Jan; Gieger, Christian; Prehn, Cornelia; Roemisch-Margl, Werner; Polonikov, Alexey; Peters, Annette; Theis, Fabian J.; Meitinger, Thomas; Kronenberg, Florian; Weidinger, Stephan; Wichmann, Heinz-Erich; Suhre, Karsten; Wang-Sattler, Rui; Adamski, Jerzy und Illig, Thomas (August 2011): Discovery of Sexual Dimorphisms in Metabolic and Genetic Biomarkers.
In: PLOS Genetics 7(8), e1002215 [PDF, 597kB]

Krumsiek, Jan; Suhre, Karsten; Illig, Thomas; Adamski, Jerzy und Theis, Fabian J. (2011): Gaussian graphical modeling reconstructs pathway reactions from high-throughput metabolomics data. In: BMC Systems Biology 5:21 [PDF, 1MB]

Konferenzbeitrag

Koch, Valentin; Holmberg, Olle; Spitzer, Hannah; Schiefelbein, Johannes; Asani, Ben; Hafner, Michael und Theis, Fabian J. (2022): Noise Transfer for Unsupervised Domain Adaptation of Retinal OCT Images. 25th International Conference on Medical Image Computing and Computer Assisted Intervention (MICCAI 2022), Singapore, September 18–22, 2022. Wang, Linwei (Hrsg.): In: Medical Image Computing and Computer Assisted Intervention – MICCAI 2022, Lecture Notes in Computer Science Bd. 13432 Cham: Springer. S. 699-708

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