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Anzahl der Publikationen: 7
Zeitschriftenartikel
Levin, Johannes; Sing, Nand; Melbourne, Sue; Morgan, Amber; Mariner, Carla; Spillantini, Maria Grazia; Wegrzynowicz, Michal; Dalley, Jeffrey W.; Langer, Simon; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Schmidt, Felix; Weckbecker, Daniel; Prager, Kai; Matthias, Torsten und Giese, Armin
(2022):
Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind placebo-controlled phase 1a trial.
In: eBioMedicine, Bd. 80, 104021
[PDF, 612kB]
Ruf, Viktoria C.; Shi, Song; Schmidt, Felix; Weckbecker, Daniel; Nübling, Georg S.; Ködel, Uwe; Mollenhauer, Brit und Giese, Armin
(2020):
Potential sources of interference with the highly sensitive detection and quantification of alpha‐synuclein seeds by qRT‐QuIC.
In: FEBS Open Bio, Bd. 10, Nr. 5: S. 883-893
[PDF, 2MB]
Maurer, Andreas; Leonov, Andrei; Ryazanov, Sergey; Herfert, Kristina; Kuebler, Laura; Buss, Sabrina; Schmidt, Felix; Weckbecker, Daniel; Linder, Ruth; Bender, Dirk; Giese, Armin; Pichler, Bernd J. und Griesinger, Christian
(2020):
C-11 Radiolabeling of anle253b: a Putative PET Tracer for Parkinson's Disease That Binds to alpha-Synuclein Fibrils in vitro and Crosses the Blood-Brain Barrier.
In: Chemmedchem, Bd. 15, Nr. 5: S. 411-415
Camilleri, Angelique; Ghio, Stephanie; Caruana, Mario; Weckbecker, Daniel; Schmidt, Felix; Kamp, Frits; Leonov, Andrei; Ryazanov, Sergey; Griesinger, Christian; Giese, Armin; Cauchi, Ruben J. und Vassallo, Neville
(2020):
Tau-induced mitochondrial membrane perturbation is dependent upon cardiolipin.
In: Biochimica et Biophysica Acta-Biomembranes, Bd. 1862, Nr. 2, 183064
Bartels, Martin; Weckbecker, Daniel; Kuhn, Peer-Hendrik; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Lichtenthaler, Stefan F.; Boetzel, Kai und Giese, Armin
(2019):
Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression.
In: Scientific Reports, Bd. 9, 9100
[PDF, 7MB]
Heras-Garvin, Antonio; Weckbecker, Daniel; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Giese, Armin; Wenning, Gregor K. und Stefanova, Nadia
(2018):
Anle138b modulates alpha-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy.
In: Movement Disorders
[PDF, 779kB]
Reiner, Anne M.; Schmidt, Felix; Ryazanov, Sergey; Leonov, Andrei; Weckbecker, Daniel; Deeg, Andreas A.; Griesinger, Christian; Giese, Armin und Zinth, Wolfgang
(2018):
Photophysics of diphenyl-pyrazole compounds in solutions and alpha-synuclein aggregates.
In: Biochimica et Biophysica Acta-General Subjects, Bd. 1862, Nr. 4: S. 800-807