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Anzahl der Publikationen: 15
Zeitschriftenartikel
Leu, Chia-Luen; Lam, Daniel D.; Salminen, Aaro; Wefers, Benedikt; Becker, Lore; Garrett, Lillian; Rozman, Jan; Wurst, Wolfgang; de Angelis, Martin Hrabe; Hoelter, Sabine M.; Winkelmann, Juliane und Williams, Rhiannan H.
(2024):
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.
In: Sleep, Bd. 47, Nr. 5
Dunot, Jade; Moreno, Sebastien; Gandin, Carine; Pousinha, Paula A.; Amici, Mascia; Dupuis, Julien; Anisimova, Margarita; Winschel, Alex; Uriot, Magalie; Petshow, Samuel J.; Mensch, Maria; Bethus, Ingrid; Giudici, Camilla; Hampel, Heike; Wefers, Benedikt; Wurst, Wolfgang 
ORCID: https://orcid.org/0000-0003-4422-7410; Naumann, Ronald; Ashby, Michael C.; Laube, Bodo; Zito, Karen; Mellor, Jack R.; Groc, Laurent; Willem, Michael und Marie, Hélène
(2024):
APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors.
In: Neuron, Bd. 112, Nr. 16, e9: S. 2708-2720
[PDF, 5MB]
ORCID: https://orcid.org/0000-0003-4422-7410; Naumann, Ronald; Ashby, Michael C.; Laube, Bodo; Zito, Karen; Mellor, Jack R.; Groc, Laurent; Willem, Michael und Marie, Hélène
(2024):
APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors.
In: Neuron, Bd. 112, Nr. 16, e9: S. 2708-2720
[PDF, 5MB]
Beaufort, Nathalie ORCID: https://orcid.org/0000-0002-7088-4206; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Podlesainski, David ORCID: https://orcid.org/0000-0002-1111-8042; Richter, Tim ORCID: https://orcid.org/0009-0003-8310-6803; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G. ORCID: https://orcid.org/0000-0003-1848-1853; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel ORCID: https://orcid.org/0000-0002-7875-0886; Beuck, Christine ORCID: https://orcid.org/0000-0001-7513-7384; Uebel, Stephan ORCID: https://orcid.org/0000-0002-3726-3942; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Todorov-Völgyi, Katalin ORCID: https://orcid.org/0009-0007-8073-9524; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu ORCID: https://orcid.org/0000-0002-9634-315X; Clausen, Tim ORCID: https://orcid.org/0000-0003-1582-6924; Huber, Robert; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Schmuck, Carsten ORCID: https://orcid.org/0000-0001-6062-0357; Giese, Michael; Kaiser, Markus ORCID: https://orcid.org/0000-0002-6540-8520; Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Rational correction of pathogenic conformational defects in HTRA1.
In: Nature Communications, Bd. 15, 5944
[PDF, 3MB]
ORCID: https://orcid.org/0000-0002-7088-4206; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree ORCID: https://orcid.org/0000-0002-8254-0777; Podlesainski, David ORCID: https://orcid.org/0000-0002-1111-8042; Richter, Tim ORCID: https://orcid.org/0009-0003-8310-6803; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G. ORCID: https://orcid.org/0000-0003-1848-1853; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel ORCID: https://orcid.org/0000-0002-7875-0886; Beuck, Christine ORCID: https://orcid.org/0000-0001-7513-7384; Uebel, Stephan ORCID: https://orcid.org/0000-0002-3726-3942; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer ORCID: https://orcid.org/0000-0001-9212-2520; Todorov-Völgyi, Katalin ORCID: https://orcid.org/0009-0007-8073-9524; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Müller, Stephan A. ORCID: https://orcid.org/0000-0003-3414-307X; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu ORCID: https://orcid.org/0000-0002-9634-315X; Clausen, Tim ORCID: https://orcid.org/0000-0003-1582-6924; Huber, Robert; Lichtenthaler, Stefan F. ORCID: https://orcid.org/0000-0003-2211-2575; Schmuck, Carsten ORCID: https://orcid.org/0000-0001-6062-0357; Giese, Michael; Kaiser, Markus ORCID: https://orcid.org/0000-0002-6540-8520; Ehrmann, Michael ORCID: https://orcid.org/0000-0002-1927-260X und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2024):
Rational correction of pathogenic conformational defects in HTRA1.
In: Nature Communications, Bd. 15, 5944
[PDF, 3MB]
Wang, Meiyue; Flaswinkel, Heinrich; Joshi, Abhinav; Napoli, Matteo ORCID: https://orcid.org/0000-0002-8197-9374; Masgrau-Alsina, Sergi; Kamper, Julia M. ORCID: https://orcid.org/0000-0002-3801-864X; Henne, Antonia ORCID: https://orcid.org/0000-0001-6870-5312; Heinz, Alexander; Berouti, Marleen; Schmacke, Niklas A. ORCID: https://orcid.org/0000-0002-3998-1139; Hiller, Karsten ORCID: https://orcid.org/0000-0001-9322-5820; Kremmer, Elisabeth; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sperandio, Markus ORCID: https://orcid.org/0000-0002-7689-3613; Ruland, Jürgen ORCID: https://orcid.org/0000-0002-8381-3597; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2024):
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation.
In: Nature Communications, Bd. 15, 6438
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-8197-9374; Masgrau-Alsina, Sergi; Kamper, Julia M. ORCID: https://orcid.org/0000-0002-3801-864X; Henne, Antonia ORCID: https://orcid.org/0000-0001-6870-5312; Heinz, Alexander; Berouti, Marleen; Schmacke, Niklas A. ORCID: https://orcid.org/0000-0002-3998-1139; Hiller, Karsten ORCID: https://orcid.org/0000-0001-9322-5820; Kremmer, Elisabeth; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Sperandio, Markus ORCID: https://orcid.org/0000-0002-7689-3613; Ruland, Jürgen ORCID: https://orcid.org/0000-0002-8381-3597; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2024):
Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation.
In: Nature Communications, Bd. 15, 6438
[PDF, 2MB]
Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Bd. 609: S. 590-596
[PDF, 10MB]
ORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID: https://orcid.org/0000-0002-4150-194X
(2022):
Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
In: Nature, Bd. 609: S. 590-596
[PDF, 10MB]
Weisheit, Isabel; Kroeger, Joseph A.; Malik, Rainer; Wefers, Benedikt; Lichtner, Peter; Wurst, Wolfgang; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X und Paquet, Dominik
(2021):
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.
In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739
ORCID: https://orcid.org/0000-0002-0654-387X und Paquet, Dominik
(2021):
Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping.
In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739
Hsia, Hung-En; Tueshaus, Johanna; Feng, Xiao; Hofmann, Laura; Wefers, Benedikt; Marciano, Denise K.; Wurst, Wolfgang und Lichtenthaler, Stefan F.
(2021):
Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.
In: Faseb Journal, Bd. 35, Nr. 9, e21813
[PDF, 1MB]
LaClair, Katherine D.; Zhou, Qihui; Michaelsen, Meike; Wefers, Benedikt; Brill, Monika S.; Janjic, Aleksandar; Rathkolb, Birgit; Farny, Daniel; Cygan, Mikolaj; de Angelis, Martin Hrabe; Wurst, Wolfgang; Neumann, Manuela; Enard, Wolfgang; Misgeld, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2020):
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 121-142
[PDF, 8MB]
Lüningschöor, Patrick; Wemer, Georg; Stroobants, Stijn; Kakuta, Soichiro; Dombert, Benjamin; Sinske, Daniela; Wanner, Renate; Luellmann-Rauch, Renate; Wefers, Benedikt; Wurst, Wolfgang; D'Hooge, Rudi; Uchiyama, Yasuo; Sendtner, Michael; Haass, Christian; Saftig, Paul; Knöll, Bernd; Capell, Anja und Damme, Markus
(2020):
The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.
In: Cell Reports, Bd. 30, Nr. 10: S. 3506-3519
[PDF, 7MB]
Takalo, Mari; Wittrahm, Rebekka; Wefers, Benedikt; Parhizkar, Samira; Jokivarsi, Kimmo; Kuulasmaa, Teemu; Makinen, Petra; Martiskainen, Henna; Wurst, Wolfgang; Xiang, Xianyuan; Marttinen, Mikael; Poutiainen, Pekka; Haapasalo, Annakaisa; Hiltunen, Mikko und Haass, Christian
(2020):
The Alzheimer's disease-associated protective Plc gamma 2-P522R variant promotes immune functions.
In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 52
[PDF, 4MB]
Werner, Georg; Damme, Markus; Schludi, Martin; Gnoerich, Johannes; Wind, Karin; Fellerer, Katrin; Wefers, Benedikt; Wurst, Wolfgang; Edbauer, Dieter; Brendel, Matthias; Haass, Christian und Capell, Anja
(2020):
Loss ofTMEM106B potentiates lysosomal andFTLD-like pathology in progranulin-deficient mice.
In: EMBO Reports, Bd. 21, Nr. 10, e50241
[PDF, 4MB]
Xiang, Xianyuan; Piers, Thomas M.; Wefers, Benedikt; Zhu, Kaichuan; Mallach, Anna; Brunner, Bettina; Kleinberger, Gernot; Song, Wilbur; Colonna, Marco; Herms, Jochen; Wurst, Wolfgang; Pocock, Jennifer M. und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
ORCID: https://orcid.org/0000-0002-4869-1627
(2017):
The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism.
In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853
Brandl, Christina; Ortiz, Oskar; Röttig, Bernhard; Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf
(2015):
Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos.
In: Febs Open Bio, Bd. 5: S. 26-35
Buchbeitrag
Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf
(2023):
Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System.
In: Saunders, Thomas L. (Hrsg.):
Transgenesis. Methods and Protocols. Methods in Molecular Biology, Bd. 2631. New York: Humana Press. S. 207-230