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Anzahl der Publikationen: 19

Zeitschriftenartikel

Asare, Yaw ORCID logoORCID: https://orcid.org/0000-0002-8946-5650; Yan, Guangyao; Schlegl, Christina; Prestel, Matthias; Vorst, Emiel P.C. van der; Teunissen, Abraham J.P.; Aronova, Arailym; Tosato, Federica; Naser, Nawraa; Caputo, Julio; Prevot, Geoffrey; Azzun, Anthony; Wefers, Benedikt; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Schneider, Melanie; Forne, Ignasi; Bidzhekov, Kiril; Naumann, Ronald; Laan, Sander W. van der ORCID logoORCID: https://orcid.org/0000-0001-6888-1404; Brandhofer, Markus; Cao, Jiayu; Roth, Stefan; Malik, Rainer; Tiedt, Steffen; Mulder, Willem J.M.; Imhof, Axel; Liesz, Arthur ORCID logoORCID: https://orcid.org/0000-0002-9069-2594; Weber, Christian ORCID logoORCID: https://orcid.org/0000-0003-4610-8714; Bernhagen, Jürgen ORCID logoORCID: https://orcid.org/0000-0003-2996-2652 und Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X (2025): A cis-regulatory element controls expression of histone deacetylase 9 to fine-tune inflammasome-dependent chronic inflammation in atherosclerosis. In: Immunity, Bd. 58, Nr. 3: S. 555-567 [PDF, 4MB]

Gomez-Diaz, Carlos ORCID logoORCID: https://orcid.org/0009-0007-8590-6993; Greulich, Wilhelm ORCID logoORCID: https://orcid.org/0009-0003-9946-4226; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Wang, Meiyue ORCID logoORCID: https://orcid.org/0000-0002-5193-3279; Bolsega, Silvia ORCID logoORCID: https://orcid.org/0009-0003-8290-8214; Effern, Maike ORCID logoORCID: https://orcid.org/0000-0002-1766-9881; Varga, Daniel P. ORCID logoORCID: https://orcid.org/0000-0001-5797-9334; Han, Zhe ORCID logoORCID: https://orcid.org/0000-0003-2544-3759; Chen, Minyi ORCID logoORCID: https://orcid.org/0000-0002-9299-5353; Bérouti, Marleen ORCID logoORCID: https://orcid.org/0009-0009-6081-5408; Leonardi, Natascia ORCID logoORCID: https://orcid.org/0009-0000-3788-8849; Schillinger, Ulrike ORCID logoORCID: https://orcid.org/0009-0005-5513-4692; Holzmann, Bernhard ORCID logoORCID: https://orcid.org/0000-0002-3356-3083; Liesz, Arthur ORCID logoORCID: https://orcid.org/0000-0002-9069-2594; Roers, Axel ORCID logoORCID: https://orcid.org/0000-0003-1806-6158; Hölzel, Michael ORCID logoORCID: https://orcid.org/0000-0003-4048-8824; Basic, Marijana ORCID logoORCID: https://orcid.org/0000-0002-1995-618X; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2025): RNase T2 restricts TLR13-mediated autoinflammation in vivo. In: Journal of Experimental Medicine, Bd. 222, Nr. 3, e20241424

Wu, Jianping ORCID logoORCID: https://orcid.org/0000-0001-6927-5772; Kislinger, Georg ORCID logoORCID: https://orcid.org/0000-0002-6559-7421; Duschek, Jerome ORCID logoORCID: https://orcid.org/0009-0001-4276-5322; Durmaz, Ayşe Damla; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Feng, Ruoqing; Nalbach, Karsten ORCID logoORCID: https://orcid.org/0000-0002-3928-4026; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Behrends, Christian ORCID logoORCID: https://orcid.org/0000-0002-9184-7607; Schifferer, Martina ORCID logoORCID: https://orcid.org/0000-0002-0500-8218 und Simons, Mikael ORCID logoORCID: https://orcid.org/0000-0001-5329-192X (2024): Nonvesicular lipid transfer drives myelin growth in the central nervous system. In: Nature Communications, Bd. 15, 9756 [PDF, 10MB]

Kaji, Seiji; Berghoff, Stefan A.; Spieth, Lena; Schlaphoff, Lennart; Sasmita, Andrew O.; Vitale, Simona; Büschgens, Luca; Kedia, Shreeya; Zirngibl, Martin; Nazarenko, Taisiia; Damkou, Alkmini; Hosang, Leon; Depp, Constanze; Kamp, Frits; Scholz, Patricia; Ewers, David; Giera, Martin; Ischebeck, Till; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Schifferer, Martina ORCID logoORCID: https://orcid.org/0000-0002-0500-8218; Willem, Michael; Nave, Klaus-Armin; Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627; Arzberger, Thomas; Jäkel, Sarah; Wirths, Oliver ORCID logoORCID: https://orcid.org/0000-0002-4115-0334; Saher, Gesine ORCID logoORCID: https://orcid.org/0000-0003-3507-9604 und Simons, Mikael ORCID logoORCID: https://orcid.org/0000-0001-5329-192X (2024): Apolipoprotein E aggregation in microglia initiates Alzheimer’s disease pathology by seeding β-amyloidosis. In: Immunity, Bd. 57, Nr. 11: S. 2651-2668 [PDF, 11MB]

Wang, Meiyue; Flaswinkel, Heinrich; Joshi, Abhinav; Napoli, Matteo ORCID logoORCID: https://orcid.org/0000-0002-8197-9374; Masgrau-Alsina, Sergi; Kamper, Julia M. ORCID logoORCID: https://orcid.org/0000-0002-3801-864X; Henne, Antonia ORCID logoORCID: https://orcid.org/0000-0001-6870-5312; Heinz, Alexander; Berouti, Marleen; Schmacke, Niklas A. ORCID logoORCID: https://orcid.org/0000-0002-3998-1139; Hiller, Karsten ORCID logoORCID: https://orcid.org/0000-0001-9322-5820; Kremmer, Elisabeth; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Sperandio, Markus ORCID logoORCID: https://orcid.org/0000-0002-7689-3613; Ruland, Jürgen ORCID logoORCID: https://orcid.org/0000-0002-8381-3597; Fröhlich, Thomas ORCID logoORCID: https://orcid.org/0000-0002-4709-3211 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2024): Phosphorylation of PFKL regulates metabolic reprogramming in macrophages following pattern recognition receptor activation. In: Nature Communications, Bd. 15, 6438 [PDF, 2MB]

Beaufort, Nathalie ORCID logoORCID: https://orcid.org/0000-0002-7088-4206; Ingendahl, Linda; Merdanovic, Melisa; Schmidt, Andree ORCID logoORCID: https://orcid.org/0000-0002-8254-0777; Podlesainski, David ORCID logoORCID: https://orcid.org/0000-0002-1111-8042; Richter, Tim ORCID logoORCID: https://orcid.org/0009-0003-8310-6803; Neumann, Thorben; Kuszner, Michael; Vetter, Ingrid R.; Stege, Patricia; Burston, Steven G. ORCID logoORCID: https://orcid.org/0000-0003-1848-1853; Filipovic, Anto; Ruiz-Blanco, Yasser B.; Bravo-Rodriguez, Kenny; Mieres-Perez, Joel ORCID logoORCID: https://orcid.org/0000-0002-7875-0886; Beuck, Christine ORCID logoORCID: https://orcid.org/0000-0001-7513-7384; Uebel, Stephan ORCID logoORCID: https://orcid.org/0000-0002-3726-3942; Zobawa, Monika; Schillinger, Jasmin; Malik, Rainer ORCID logoORCID: https://orcid.org/0000-0001-9212-2520; Todorov-Völgyi, Katalin ORCID logoORCID: https://orcid.org/0009-0007-8073-9524; Rey, Juliana; Roberti, Annabell; Hagemeier, Birte; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Müller, Stephan A. ORCID logoORCID: https://orcid.org/0000-0003-3414-307X; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Sanchez-Garcia, Elsa; Zimmermann, Alexander; Hu, Xiao-Yu ORCID logoORCID: https://orcid.org/0000-0002-9634-315X; Clausen, Tim ORCID logoORCID: https://orcid.org/0000-0003-1582-6924; Huber, Robert; Lichtenthaler, Stefan F. ORCID logoORCID: https://orcid.org/0000-0003-2211-2575; Schmuck, Carsten ORCID logoORCID: https://orcid.org/0000-0001-6062-0357; Giese, Michael; Kaiser, Markus ORCID logoORCID: https://orcid.org/0000-0002-6540-8520; Ehrmann, Michael ORCID logoORCID: https://orcid.org/0000-0002-1927-260X und Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X (2024): Rational correction of pathogenic conformational defects in HTRA1. In: Nature Communications, Bd. 15, 5944 [PDF, 3MB]

Dunot, Jade; Moreno, Sebastien; Gandin, Carine; Pousinha, Paula A.; Amici, Mascia; Dupuis, Julien; Anisimova, Margarita; Winschel, Alex; Uriot, Magalie; Petshow, Samuel J.; Mensch, Maria; Bethus, Ingrid; Giudici, Camilla; Hampel, Heike; Wefers, Benedikt; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Naumann, Ronald; Ashby, Michael C.; Laube, Bodo; Zito, Karen; Mellor, Jack R.; Groc, Laurent; Willem, Michael und Marie, Hélène (2024): APP fragment controls both ionotropic and non-ionotropic signaling of NMDA receptors. In: Neuron, Bd. 112, Nr. 16, e9: S. 2708-2720 [PDF, 5MB]

Leu, Chia-Luen; Lam, Daniel D.; Salminen, Aaro; Wefers, Benedikt; Becker, Lore; Garrett, Lillian; Rozman, Jan; Wurst, Wolfgang; de Angelis, Martin Hrabe; Hoelter, Sabine M.; Winkelmann, Juliane und Williams, Rhiannan H. (2024): A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice. In: Sleep, Bd. 47, Nr. 5

Stafford, Che A.; Gassauer, Alicia-Marie; Oliveira Mann, Carina C. de; Tanzer, Maria C. ORCID logoORCID: https://orcid.org/0000-0002-4657-9869; Fessler, Evelyn; Wefers, Benedikt ORCID logoORCID: https://orcid.org/0000-0002-2492-9389; Nagl, Dennis; Kuut, Gunnar; Sulek, Karolina; Vasilopoulou, Catherine; Schwojer, Sophia J. ORCID logoORCID: https://orcid.org/0000-0002-1747-4144; Wiest, Andreas ORCID logoORCID: https://orcid.org/0000-0003-2525-6304; Pfautsch, Marie K.; Wurst, Wolfgang ORCID logoORCID: https://orcid.org/0000-0003-4422-7410; Yabal, Monica ORCID logoORCID: https://orcid.org/0000-0003-3495-7671; Fröhlich, Thomas ORCID logoORCID: https://orcid.org/0000-0002-4709-3211; Mann, Matthias ORCID logoORCID: https://orcid.org/0000-0003-1292-4799; Gisch, Nicolas ORCID logoORCID: https://orcid.org/0000-0003-3260-5269; Jae, Lucas T. ORCID logoORCID: https://orcid.org/0000-0002-3531-1760 und Hornung, Veit ORCID logoORCID: https://orcid.org/0000-0002-4150-194X (2022): Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation. In: Nature, Bd. 609: S. 590-596 [PDF, 10MB]

Hsia, Hung-En; Tueshaus, Johanna; Feng, Xiao; Hofmann, Laura; Wefers, Benedikt; Marciano, Denise K.; Wurst, Wolfgang und Lichtenthaler, Stefan F. (2021): Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons. In: Faseb Journal, Bd. 35, Nr. 9, e21813 [PDF, 1MB]

Weisheit, Isabel; Kroeger, Joseph A.; Malik, Rainer; Wefers, Benedikt; Lichtner, Peter; Wurst, Wolfgang; Dichgans, Martin ORCID logoORCID: https://orcid.org/0000-0002-0654-387X und Paquet, Dominik (2021): Simple and reliable detection of CRISPR-induced on-target effects by qgPCR and SNP genotyping. In: Nature Protocols, Bd. 16, Nr. 3: S. 1714-1739

Werner, Georg; Damme, Markus; Schludi, Martin; Gnoerich, Johannes; Wind, Karin; Fellerer, Katrin; Wefers, Benedikt; Wurst, Wolfgang; Edbauer, Dieter; Brendel, Matthias; Haass, Christian und Capell, Anja (2020): Loss ofTMEM106B potentiates lysosomal andFTLD-like pathology in progranulin-deficient mice. In: EMBO Reports, Bd. 21, Nr. 10, e50241 [PDF, 4MB]

Takalo, Mari; Wittrahm, Rebekka; Wefers, Benedikt; Parhizkar, Samira; Jokivarsi, Kimmo; Kuulasmaa, Teemu; Makinen, Petra; Martiskainen, Henna; Wurst, Wolfgang; Xiang, Xianyuan; Marttinen, Mikael; Poutiainen, Pekka; Haapasalo, Annakaisa; Hiltunen, Mikko und Haass, Christian (2020): The Alzheimer's disease-associated protective Plc gamma 2-P522R variant promotes immune functions. In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 52 [PDF, 4MB]

Lüningschöor, Patrick; Wemer, Georg; Stroobants, Stijn; Kakuta, Soichiro; Dombert, Benjamin; Sinske, Daniela; Wanner, Renate; Luellmann-Rauch, Renate; Wefers, Benedikt; Wurst, Wolfgang; D'Hooge, Rudi; Uchiyama, Yasuo; Sendtner, Michael; Haass, Christian; Saftig, Paul; Knöll, Bernd; Capell, Anja und Damme, Markus (2020): The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons. In: Cell Reports, Bd. 30, Nr. 10: S. 3506-3519 [PDF, 7MB]

LaClair, Katherine D.; Zhou, Qihui; Michaelsen, Meike; Wefers, Benedikt; Brill, Monika S.; Janjic, Aleksandar; Rathkolb, Birgit; Farny, Daniel; Cygan, Mikolaj; de Angelis, Martin Hrabe; Wurst, Wolfgang; Neumann, Manuela; Enard, Wolfgang; Misgeld, Thomas; Arzberger, Thomas und Edbauer, Dieter (2020): Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS. In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 121-142 [PDF, 8MB]

Xiang, Xianyuan; Piers, Thomas M.; Wefers, Benedikt; Zhu, Kaichuan; Mallach, Anna; Brunner, Bettina; Kleinberger, Gernot; Song, Wilbur; Colonna, Marco; Herms, Jochen; Wurst, Wolfgang; Pocock, Jennifer M. und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2018): The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans. In: Molecular Neurodegeneration 13:49 [PDF, 2MB]

Kleinberger, Gernot; Brendel, Matthias; Mracsko, Eva; Wefers, Benedikt; Groeneweg, Linda; Xiang, Xianyuan; Focke, Carola; Deußing, Maximilian; Suarez-Calvet, Marc; Mazaheri, Fargol; Parhizkar, Samira; Pettkus, Nadine; Wurst, Wolfgang; Feederle, Regina; Bartenstein, Peter; Mueggler, Thomas; Arzberger, Thomas; Knuesel, Irene; Rominger, Axel und Haass, Christian ORCID logoORCID: https://orcid.org/0000-0002-4869-1627 (2017): The FTD-like syndrome causing TREM2 T66M mutation impairs microglia function, brain perfusion, and glucose metabolism. In: Embo Journal, Bd. 36, Nr. 13: S. 1837-1853

Brandl, Christina; Ortiz, Oskar; Röttig, Bernhard; Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf (2015): Creation of targeted genomic deletions using TALEN or CRISPR/Cas nuclease pairs in one-cell mouse embryos. In: Febs Open Bio, Bd. 5: S. 26-35

Buchbeitrag

Wefers, Benedikt; Wurst, Wolfgang und Kühn, Ralf (2023): Gene Editing in Mouse Zygotes Using the CRISPR/Cas9 System. In: Saunders, Thomas L. (Hrsg.): Transgenesis. Methods and Protocols. Methods in Molecular Biology, Bd. 2631. New York: Humana Press. S. 207-230

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