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Eine Ebene höherGruppiert nach: Dokumententyp |
Veröffentlichungsdatum
Anzahl der Publikationen: 21
2024
Windisch, Roland 
ORCID: https://orcid.org/0000-0003-1294-5151; Soliman, Sarah; Hoffmann, Adrian; Chen-Wichmann, Linping ORCID: https://orcid.org/0009-0003-8439-8107; Danese, Anna; Vosberg, Sebastian ORCID: https://orcid.org/0000-0002-8464-1483; Bravo, Jimena; Lutz, Sebastian; Kellner, Christian ORCID: https://orcid.org/0000-0002-2562-6902; Fischer, Alexander ORCID: https://orcid.org/0000-0001-8876-5566; Gebhard, Claudia ORCID: https://orcid.org/0000-0002-5459-8381; Redondo Monte, Enric; Hartmann, Luise; Schneider, Stephanie; Beier, Fabian ORCID: https://orcid.org/0000-0002-3718-8217; Strobl, Carolin Dorothea ORCID: https://orcid.org/0000-0003-2257-6281; Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373; Peipp, Matthias; Schündeln, Michael ORCID: https://orcid.org/0000-0001-7495-9060; Stricker, Stefan H. ORCID: https://orcid.org/0000-0002-5488-8530; Rehli, Michael ORCID: https://orcid.org/0000-0003-3992-932X; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652; Humpe, Andreas; Klump, Hannes ORCID: https://orcid.org/0000-0003-3536-1212; Brendel, Christian ORCID: https://orcid.org/0000-0003-4081-4351; Krause, Daniela S. ORCID: https://orcid.org/0000-0003-3603-1119; Greif, Philipp A. ORCID: https://orcid.org/0000-0002-3744-7936 und Wichmann, Christian
(2024):
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
In: Proceedings of the National Academy of Sciences, Bd. 121, Nr. 25, e2312499121
[PDF, 6MB]
ORCID: https://orcid.org/0000-0003-1294-5151; Soliman, Sarah; Hoffmann, Adrian; Chen-Wichmann, Linping ORCID: https://orcid.org/0009-0003-8439-8107; Danese, Anna; Vosberg, Sebastian ORCID: https://orcid.org/0000-0002-8464-1483; Bravo, Jimena; Lutz, Sebastian; Kellner, Christian ORCID: https://orcid.org/0000-0002-2562-6902; Fischer, Alexander ORCID: https://orcid.org/0000-0001-8876-5566; Gebhard, Claudia ORCID: https://orcid.org/0000-0002-5459-8381; Redondo Monte, Enric; Hartmann, Luise; Schneider, Stephanie; Beier, Fabian ORCID: https://orcid.org/0000-0002-3718-8217; Strobl, Carolin Dorothea ORCID: https://orcid.org/0000-0003-2257-6281; Weigert, Oliver ORCID: https://orcid.org/0000-0002-0987-7373; Peipp, Matthias; Schündeln, Michael ORCID: https://orcid.org/0000-0001-7495-9060; Stricker, Stefan H. ORCID: https://orcid.org/0000-0002-5488-8530; Rehli, Michael ORCID: https://orcid.org/0000-0003-3992-932X; Bernhagen, Jürgen ORCID: https://orcid.org/0000-0003-2996-2652; Humpe, Andreas; Klump, Hannes ORCID: https://orcid.org/0000-0003-3536-1212; Brendel, Christian ORCID: https://orcid.org/0000-0003-4081-4351; Krause, Daniela S. ORCID: https://orcid.org/0000-0003-3603-1119; Greif, Philipp A. ORCID: https://orcid.org/0000-0002-3744-7936 und Wichmann, Christian
(2024):
Engineering an inducible leukemia-associated fusion protein enables large-scale ex vivo production of functional human phagocytes.
In: Proceedings of the National Academy of Sciences, Bd. 121, Nr. 25, e2312499121
[PDF, 6MB]
Schewe, Denis M.; Vogiatzi, Fotini; Münnich, Ira A.; Zeller, Tobias; Windisch, Roland; Wichmann, Christian; Müller, Kristina; Bhat, Hilal; Felix, Elisa; Mougiakakos, Dimitrios; Bruns, Heiko; Lenk, Lennart; Valerius, Thomas; Humpe, Andreas; Peipp, Matthias und Kellner, Christian ORCID: https://orcid.org/0000-0002-2562-6902
(2024):
Enhanced potency of immunotherapy against B‐cell precursor acute lymphoblastic leukemia by combination of an Fc‐engineered CD19 antibody and CD47 blockade.
In: HemaSphere, Bd. 8, Nr. 2
[PDF, 1MB]
ORCID: https://orcid.org/0000-0002-2562-6902
(2024):
Enhanced potency of immunotherapy against B‐cell precursor acute lymphoblastic leukemia by combination of an Fc‐engineered CD19 antibody and CD47 blockade.
In: HemaSphere, Bd. 8, Nr. 2
[PDF, 1MB]
Ebner, Benedikt ORCID: https://orcid.org/0000-0003-2126-7305; Fleckenstein, Franka; Volz, Yannic ORCID: https://orcid.org/0000-0002-5468-9398; Eismann, Lennert; Hermans, Julian; Buchner, Alexander ORCID: https://orcid.org/0000-0001-7895-7070; Enzinger, Benazir; Weinhold, Philipp; Wichmann, Christian; Stief, Christian Georg; Humpe, Andreas; Pyrgidis, Nikolaos und Schulz, Gerald Bastian
(2024):
Oncological impact of perioperative blood transfusion in bladder cancer patients undergoing radical cystectomy: Do we need to consider storage time of blood units, donor age, or gender matching?
In: Transfusion, Bd. 64, Nr. 1: S. 29-38
[PDF, 2MB]
ORCID: https://orcid.org/0000-0003-2126-7305; Fleckenstein, Franka; Volz, Yannic ORCID: https://orcid.org/0000-0002-5468-9398; Eismann, Lennert; Hermans, Julian; Buchner, Alexander ORCID: https://orcid.org/0000-0001-7895-7070; Enzinger, Benazir; Weinhold, Philipp; Wichmann, Christian; Stief, Christian Georg; Humpe, Andreas; Pyrgidis, Nikolaos und Schulz, Gerald Bastian
(2024):
Oncological impact of perioperative blood transfusion in bladder cancer patients undergoing radical cystectomy: Do we need to consider storage time of blood units, donor age, or gender matching?
In: Transfusion, Bd. 64, Nr. 1: S. 29-38
[PDF, 2MB]
2023
Kendirli, Arek; de la Rosa, Clara; Laemmle, Katrin F.; Eglseer, Klara; Bauer, Isabel J.; Kavaka, Vladyslav; Winklmeier, Stephan; Zhuo, La; Wichmann, Christian; Gerdes, Lisa Ann; Kuempfel, Tania; Dornmair, Klaus; Beltran, Eduardo; Kerschensteiner, Martin und Kawakami, Naoto
(2023):
A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model.
In: Nature Neuroscience, Bd. 26, Nr. 10:
1713-+
[PDF, 16MB]
Klein, Lisa Monika; Walter, Julia; Vorstandlechner, Maximilian; Schneider, Christian P.; Michel, Sebastian; Kneidinger, Nikolaus ORCID: https://orcid.org/0000-0001-7583-0453; Irlbeck, Michael; Wichmann, Christian; Möhnle, Patrick; Humpe, Andreas; Kauke, Teresa ORCID: https://orcid.org/0000-0001-6569-9703 und Dick, Andrea
(2023):
Predictive value of molecular matching tools for the development of donor specific HLA‐antibodies in patients undergoing lung transplantation.
In: HLA, Bd. 102, Nr. 3: S. 331-342
[PDF, 1MB]
ORCID: https://orcid.org/0000-0001-7583-0453; Irlbeck, Michael; Wichmann, Christian; Möhnle, Patrick; Humpe, Andreas; Kauke, Teresa ORCID: https://orcid.org/0000-0001-6569-9703 und Dick, Andrea
(2023):
Predictive value of molecular matching tools for the development of donor specific HLA‐antibodies in patients undergoing lung transplantation.
In: HLA, Bd. 102, Nr. 3: S. 331-342
[PDF, 1MB]
2022
Zeller, Tobias; Lutz, Sebastian; Münnich, Ira A.; Windisch, Roland; Hilger, Patricia; Herold, Tobias; Tahiri, Natyra; Banck, Jan C.; Weigert, Oliver; Moosmann, Andreas; von Bergwelt-Baildon, Michael; Flamann, Cindy; Bruns, Heiko; Wichmann, Christian; Baumann, Niklas; Valerius, Thomas; Schewe, Denis M.; Peipp, Matthias; Rösner, Thies; Humpe, Andreas und Kellner, Christian
(27. Oktober 2022):
Dual checkpoint blockade of CD47 and LILRB1 enhances CD20 antibody-dependent phagocytosis of lymphoma cells by macrophages.
In: Frontiers in Immunology, Bd. 13
[PDF, 21MB]
Leubolt, Georg; Windisch, Roland; Kerbs, Paul; Dutta, Sayantanee; Landspersky, Theresa; Istvanffy, Rouzanna; Chen-Wichmann, Linping; Herold, Tobias; Cusan, Monica; Schotta, Gunnar; Wichmann, Christian; Greif, Philipp A. A.; Monte, Enric Redondo und Oostendorp, Robert A. J.
(2022):
Specific effects of somatic GATA2 zinc finger mutations on erythroid differentiation.
In: Experimental Hematology, Bd. 108: S. 26-35
Kunz, Patrick; Stuckenberger, Eva; Hausmann, Kerstin; Gentiluomo, Lorenzo; Neustrup, Malene; Michalakis, Stylianos; Rieser, Ruth; Romeijn, Stefan; Wichmann, Christian; Windisch, Roland; Hawe, Andrea; Jiskoot, Wim und Menzen, Tim
(2022):
Understanding opalescence measurements of biologics-A comparison study of methods, standards, and molecules.
In: International Journal of Pharmaceutics, Bd. 628, 122321
2021
Kellner, Christian; Lutz, Sebastian; Oberg, Hans-Heinrich; Wesch, Daniela; Otte, Anna; Diemer, Katarina J.; Wilcken, Hauke; Bauerschlag, Dirk; Glueer, Claus-Christian; Wichmann, Christian; Kabelitz, Dieter; Leusen, Jeanette H. W.; Klausz, Katja; Humpe, Andreas; Gramatzki, Martin und Peipp, Matthias
(2021):
Tumor cell lysis and synergistically enhanced antibody-dependent cell-mediated cytotoxicity by NKG2D engagement with a bispecific immunoligand targeting the HER2 antigen.
In: Biological Chemistry, Bd. 403, Nr. 5-6: S. 545-556
Jakobczyk, Helene; Debaize, Lydie; Soubise, Benoit; Avner, Stephane; Rouger-Gaudichon, Jeremie; Commet, Severine; Jiang, Yan; Serandour, Aurelien A.; Rio, Anne-Gaelle; Carroll, Jason S.; Wichmann, Christian; Lie-a-Ling, Michael; Lacaud, Georges; Corcos, Laurent; Salbert, Gilles; Galibert, Marie-Dominique; Gandemer, Virginie und Troadec, Marie-Berengere
(2021):
Reduction of RUNX1 transcription factor activity by a CBFA2T3-mimicking peptide: application to B cell precursor acute lymphoblastic leukemia.
In: Journal of Hematology & Oncology, Bd. 14, Nr. 1, 47
2020
Redondo Monte, Enric; Wilding, Anja; Leubolt, Georg; Kerbs, Paul; Bagnoli, Johannes W.; Hartmann, Luise; Hiddemann, Wolfgang; Chen-Wichmann, Linping; Krebs, Stefan; Blum, Helmut; Cusan, Monica; Vick, Binje; Jeremias, Irmela; Enard, Wolfgang; Theurich, Sebastian; Wichmann, Christian und Greif, Philipp A.
(2020):
ZBTB7A prevents RUNX1-RUNX1T1-dependent clonal expansion of human hematopoietic stem and progenitor cells.
In: Oncogene, Bd. 39: S. 3195-3205
[PDF, 1MB]
2019
Chen-Wichmann, Linping; Shvartsman, Marina; Preiss, Caro; Hockings, Colin; Windisch, Roland; Monte, Enric Redondo; Leubolt, Georg; Spiekermann, Karsten; Lausen, Jorn; Brendel, Christian; Grez, Manuel; Greif, Philipp A. und Wichmann, Christian
(2019):
Compatibility of RUNX1/ETO fusion protein modules driving CD34+human progenitor cell expansion.
In: Oncogene, Bd. 38, Nr. 2: S. 261-272
Windisch, Roland; Pirschtat, Nina; Kellner, Christian; Chen-Wichmann, Linping; Lausen, Jörn; Humpe, Andreas; Krause, Daniela S. und Wichmann, Christian
(2019):
Oncogenic Deregulation of Cell Adhesion Molecules in Leukemia.
In: Cancers, Bd. 11, Nr. 3, 311
2018
Martinez-Soria, Natalia; McKenzie, Lynsey; Draper, Julia; Ptasinska, Anetta; Issa, Hasan; Potluri, Sandeep; Blair, Helen J.; Pickin, Anna; Isa, Asmida; Chin, Paulynn Suyin; Tirtakusuma, Ricky; Coleman, Daniel; Nakjang, Sirintra; Assi, Salam; Forster, Victoria; Reza, Mojgan; Law, Ed; Berry, Philip; Müller, Dorothee; Elder, Alex; Bomken, Simon N.; Pal, Deepali; Allan, James M.; Veal, Gareth J.; Cockerill, Peter N.; Wichmann, Christian; Vormoor, Josef; Lacaud, Georges; Bonifer, Constanze und Heidenreich, Olaf
(2018):
The Oncogenic Transcription Factor RUNX1/ETO Corrupts Cell Cycle Regulation to Drive Leukemic Transformation.
In: Cancer Cell, Bd. 34, Nr. 4: S. 626-642
Pons, Miriam; Reichardt, Claudia M.; Hennig, Dorle; Nathan, Abinaya; Kiweler, Nicole; Stocking, Carol; Wichmann, Christian; Christmann, Markus; Butter, Falk; Reichardt, Sigrid; Schneider, Guenter; Heinzel, Thorsten; Englert, Christoph; Hartkamp, Jörg; Kraemer, Oliver H. und Mahendrarajah, Nisintha
(2018):
Loss of Wilms tumor 1 protein is a marker for apoptosis in response to replicative stress in leukemic cells.
In: Archives of Toxicology, Bd. 92, Nr. 6: S. 2119-2135
2017
Preiss, Carolin; Chen-Wichmann, Linping; Shvartsman, Marina; Hockings, Colin; Leubolt, Georg; Redondo-Monte, Enric; Brendel, Christian; Buhmann, Raymund; Greif, Philipp A. und Wichmann, Christian
(2017):
Temporal but Distinct Requirements of a Transcriptional Repressor Domain for RUNX1/ETO Driven Human CD34+Progenitor Cell Transformation.
In: Annals of Hematology, Bd. 96:
S50-S50
Moslem, Mohsen; Eggenschwiler, Reto; Wichmann, Christian; Buhmann, Raymund; Cantz, Tobias und Henschler, Reinhard
(2017):
Kindlin-2 Modulates the Survival, Differentiation, and Migration of Induced Pluripotent Cell-Derived Mesenchymal Stromal Cells.
In: Stem Cells international, Bd. 2017, 7316354
[PDF, 2MB]
Thirant, Cecile; Ignacimouttou, Cathy; Lopez, Cecile K.; Diop, M'Boyba; Le Mouel, Lou; Thiollier, Clarisse; Siret, Aurelie; Dessen, Phillipe; Aid, Zakia; Riviere, Julie; Rameau, Philippe; Lefebvre, Ce ' Line; Khaled, Mehdi; Leverger, Guy; Ballerini, Paola; Petit, Arnaud; Raslova, Hana; Carmichael, Catherine L.; Kile, Benjamin T.; Soler, Eric; Crispino, John D.; Wichmann, Christian; Pflumio, Francoise; Schwaller, Jurg; Vainchenker, William; Lobry, Camille; Droin, Nathalie; Bernard, Olivier A.; Malinge, Sebastien und Mercher, Thomas
(2017):
ETO2-GLIS2 Hijacks Transcriptional Complexes to Drive Cellular Identity and Self-Renewal in Pediatric Acute Megakaryoblastic Leukemia.
In: Cancer Cell, Bd. 31, Nr. 3: S. 452-465
Schanda, Julia; Lee, Chun-Wei; Wohlan, Katharina; Müller-Kuller, Uta; Kunkel, Hana; Coco, Isabell Quagliano-Lo; Stein, Stefan; Metz, Alexander; Koch, Joachim; Lausen, Jorn; Platzbecker, Uwe; Medyouf, Hind; Gohlke, Holger; Heuser, Michael; Eder, Matthias; Grez, Manuel; Scherr, Michaela und Wichmann, Christian
(2017):
Suppression of RUNX1/ETO oncogenic activity by a small molecule inhibitor of tetramerization.
In: Haematologica, Bd. 102, Nr. 5, E170-E174
2016
Hartmann, Luise; Dutta, Sayantanee; Opatz, Sabrina; Vosberg, Sebastian; Reiter, Katrin; Leubolt, Georg; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Hopfner, Karl-Peter; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Middeke, Jan Moritz; Stölzel, Friedrich; Thiede, Christian; Wolf, Stephan; Bohlander, Stefan K.; Preiss, Caroline; Chen-Wichmann, Linping; Wichmann, Christian; Sauerland, Maria Cristina; Büchner, Thomas; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten und Greif, Philipp A.
(2016):
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
In: Nature Communications, Bd. 7, 11733
[PDF, 1MB]
Kohrs, Nicole; Kolodziej, Stephan; Kuvardina, Olga N.; Herglotz, Julia; Yillah, Jasmin; Herkt, Stefanie; Piechatzek, Alexander; Riester, Gabriela Salinas; Lingner, Thomas; Wichmann, Christian; Bonig, Halvard; Seifried, Erhard; Platzbecker, Uwe; Medyouf, Hind; Grez, Manuel und Lausen, Jörn
(2016):
MiR144/451 Expression Is Repressed by RUNX1 During Megakaryopoiesis and Disturbed by RUNX1/ETO.
In: PLOS Genetics 12(3), e1005946 [PDF, 2MB]
In: PLOS Genetics 12(3), e1005946 [PDF, 2MB]