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Anzahl der Publikationen: 32
Zeitschriftenartikel
Ghiboub, Mohammed; Koster, Jan; Craggs, Peter D.; Li Yim, Andrew Y. F.; Shillings, Anthony; Hutchinson, Sue; Bingham, Ryan P.; Gatfield, Kelly; Hageman, Ishtu L.; Yao, Gang; O'Keefe, Heather P.; Coffin, Aaron; Patel, Amish; Sloan, Lisa A.; Mitchell, Darren J.; Hayhow, Thomas G.; Lunven, Laurent; Watson, Robert J.; Blunt, Christopher E.; Harrison, Lee A.; Bruton, Gordon; Kumar, Umesh; Hamer, Natalie; Spaull, John R.; Zwijnenburg, Danny A.; Welting, Olaf; Hakvoort, Theodorus B. M.; Velde, Anje A. te; Limbergen, Johan van; Henneman, Peter; Prinjha, Rab K.; Winther, Menno P. J. de; Harker, Nicola R.; Tough, David F. und Jonge, Wouter J. de
(2022):
Modulation of macrophage inflammatory function through selective inhibition of the epigenetic reader protein SP140.
In: BMC Biology, Bd. 20, Nr. 1, 182
Kwant, Lianne E.; Vegting, Yosta; Tsang-a-Sjoe, Michel W. P.; Kwakernaak, Arjan J.; Vogt, Liffert; Voskuyl, Alexandre E.; Vollenhoven, Ronald F. van; Winther, Menno P. J. de; Bemelman, Frederike J.; Anders, Hans-Joachim und Hilhorst, Marc L.
(2022):
Macrophages in Lupus Nephritis: Exploring a potential new therapeutic avenue.
In: Autoimmunity Reviews, Bd. 21, Nr. 12, 103211
Ghiboub, Mohammed; Zhao, Jing; Li Yim, Andrew Y. F.; Schilderink, Ronald; Verseijden, Caroline; Hamersveld, Patricia H. P. van; Duarte, Jose M.; Hakvoort, Theodorus B. M.; Admiraal, Iris; Harker, Nicola R.; Tough, David F.; Henneman, Peter; Winther, Menno P. J. de und Jonge, Wouter J. de
(Oktober 2020):
HDAC3 Mediates the Inflammatory Response and LPS Tolerance in Human Monocytes and Macrophages.
In: Frontiers in Immunology, Bd. 11, 550769: S. 1-14
[PDF, 1MB]
Chen, Hung-Jen; Tas, Sander W. und Winther, Menno P. J. de
(2020):
Type-I interferons in atherosclerosis.
In: Journal of Experimental Medicine, Bd. 217, Nr. 1, e20190459
Kuznetsova, Tatyana; Prange, Koen H. M.; Glass, Christopher K. und Winther, Menno P. J. de
(2020):
Transcriptional and epigenetic regulation of macrophages in atherosclerosis.
In: Nature Reviews Cardiology, Bd. 17, Nr. 4: S. 216-228
Willemsen, Lisa und Winther, Menno P. J. de
(2020):
Macrophage subsets in atherosclerosis as defined by single-cell technologies.
In: Journal of Pathology, Bd. 250, Nr. 5: S. 705-714
Poels, Kikkie; Leent, Mandy M. T. van; Reiche, Myrthe E.; Kusters, Pascal J. H.; Huveneers, Stephan; Winther, Menno P. J. de; Mulder, Willem J. M.; Lutgens, Esther und Seijkens, Tom T. P.
(2020):
Antibody-Mediated Inhibition of CTLA4 Aggravates Atherosclerotic Plaque Inflammation and Progression in Hyperlipidemic Mice.
In: Cells, Bd. 9, Nr. 9, 1987
Schnitzler, Johan G.; Hoogeveen, Renate M.; Ali, Lubna; Prange, Koen H. M.; Waissi, Farahnaz; Weeghel, Michel van; Bachmann, Julian C.; Versloot, Miranda; Borrelli, Matthew J.; Yeang, Calvin; Kleijn, Dominique P. V. de; Houtkooper, Riekelt H.; Koschinsky, Marlys L.; Winther, Menno P. J. de; Groen, Albert K.; Witztum, Joseph L.; Tsimikas, Sotirios; Stroes, Erik S. G. und Kroon, Jeffrey
(2020):
Atherogenic Lipoprotein(a) Increases Vascular Glycolysis, Thereby Facilitating Inflammation and Leukocyte Extravasation.
In: Circulation Research, Bd. 126, Nr. 10: S. 1346-1359
Shami, Annelie; Atzler, Dorothee; Bosmans, Laura A.; Winkels, Holger; Meiler, Svenja; Lacy, Michael; Tiel, Claudia van; Megens, Remco Ta; Nitz, Katrin; Baardman, Jeroen; Kusters, Pascal; Seijkens, Tom; Buerger, Christina; Janjic, Aleksandar; Riccardi, Carlo; Edsfeldt, Andreas; Monaco, Claudia; Daemen, Mat; Winther, Menno P. J. de; Nilsson, Jan; Weber, Christian; Gerdes, Norbert; Goncalves, Isabel und Lutgens, Esther
(2020):
Glucocorticoid-induced tumour necrosis factor receptor family-related protein (GITR) drives atherosclerosis in mice and is associated with an unstable plaque phenotype and cerebrovascular events in humans.
In: European Heart Journal, Bd. 41, Nr. 31: S. 2938-2948
Stiekema, Lotte C. A.; Prange, Koen H. M.; Hoogeveen, Renate M.; Verweij, Simone L.; Kroon, Jeffrey; Schnitzler, Johan G.; Dzobo, Kim E.; Cupido, Arjen J.; Tsimikas, Sotirios; Stroes, Erik S. G.; Winther, Menno P. J. de und Bahjat, Mahnoush
(2020):
Potent lipoprotein(a) lowering following apolipoprotein(a) antisense treatment reduces the pro-inflammatory activation of circulating monocytes in patients with elevated lipoprotein(a).
In: European Heart Journal, Bd. 41, Nr. 24: S. 2262-2271
Baardman, Jeroen; Verberk, Sanne G. S.; Velden, Saskia van der; Gijbels, Marion J. J.; Roomen, Cindy P. P. A. van; Sluimer, Judith C.; Broos, Jelle Y.; Griffith, Guillermo R.; Prange, Koen H. M.; Weeghel, Michel van; Lakbir, Soufyan; Molenaar, Douwe; Meinster, Elisa; Neele, Annette E.; Kooij, Gijs; Vries, Helga E. de; Lutgens, Esther; Wellen, Kathryn E.; Winther, Menno P. J. de und Bossche, Jan van den
(2020):
Macrophage ATP citrate lyase deficiency stabilizes atherosclerotic plaques.
In: Nature Communications, Bd. 11, Nr. 1, 6296
[PDF, 2MB]
Poels, Kikkie; Leent, Mandy M. T. van; Boutros, Celine; Tissot, Hubert; Roy, Severine; Meerwaldt, Anu E.; Toner, Yohana C. A.; Reiche, Myrthe E.; Kusters, Pascal J. H.; Malinova, Tsveta; Huveneers, Stephan; Kaufman, Audrey E.; Mani, Venkatesh; Fayad, Zahi A.; Winther, Menno P. J. de; Marabelle, Aurelien; Mulder, Willem J. M.; Robert, Caroline; Seijkens, Tom T. P. und Lutgens, Esther
(2020):
Immune Checkpoint Inhibitor Therapy Aggravates T Cell-Driven Plaque Inflammation in Atherosclerosis.
In: Jacc: Cardiooncology, Bd. 2, Nr. 4: S. 599-610
Tilstam, Pathricia V.; Soppert, Josefin; Hemmers, Christian; Harlacher, Eva; Döring, Yvonne; Vorst, Emiel P. C. van der; Schulte, Corinna; Alampour-Rajabi, Setareh; Theelen, Wendy; Asare, Yaw; Winther, Menno P. J. de; Lawrence, Toby; Bernhagen, Jürgen; Schober, Andreas; Zernecke, Alma; Jankowski, Joachim; Weber, Christian und Noels, Heidi
(2020):
Non-activatable mutant of inhibitor of kappa B kinase alpha (IKK alpha) exerts vascular site-specific effects on atherosclerosis in Apoe-deficient mice.
In: Atherosclerosis, Bd. 292: S. 23-30
Luque-Martin, Rosario; Van den Bossche, Jan; Furze, Rebecca C.; Neele, Annette E.; Velden, Saskia van der; Gijbels, Marion J. J.; Roomen, Cindy P. P. A. van; Bernard, Sharon G.; Jonge, Wouter J. de; Rioja, Inmaculada; Prinjha, Rab K.; Lewis, Huw D.; Mander, Palwinder K. und Winther, Menno P. J. de
(29. Oktober 2019):
Targeting Histone Deacetylases in Myeloid Cells Inhibits Their Maturation and Inflammatory Function With Limited Effects on Atherosclerosis.
In: Frontiers in Pharmacology, Bd. 10, 1242
[PDF, 4MB]
Kuipers, Eline N.; Kantae, Vasudev; Maarse, Boukje C. Eveleens; Berg, Susan M. van den; Eenige, Robin van; Nahon, Kimberly J.; Reifel-Miller, Anne; Coskun, Tamer; Winther, Menno P. J. de; Lutgens, Esther; Kooijman, Sander; Harms, Amy C.; Hankemeier, Thomas; Stelt, Mario van der; Rensen, Patrick C. N. und Boon, Marietta R.
(10. Januar 2019):
High Fat Diet Increases Circulating Endocannabinoids Accompanied by Increased Synthesis Enzymes in Adipose Tissue.
In: Frontiers in Physiology, Bd. 9, 1913
[PDF, 3MB]
Hoogeveen, Renate M.; Nahrendorf, Matthias; Riksen, Niels P.; Netea, Mihai G.; Winther, Menno P. J. de; Lutgens, Esther; Nordestgaard, Borge G.; Neidhart, Michel; Stroes, Erik S. G.; Catapano, Alberico L. und Bekkering, Siroon
(2018):
Monocyte and haematopoietic progenitor reprogramming as commonmechanism underlying chronic inflammatory and cardiovascular diseases.
In: European Heart Journal, Bd. 39, Nr. 38: S. 3521-3527
Seijkens, Tom T. P.; Tiel, Claudia M. van; Kusters, Pascal J. H.; Atzler, Dorothee; Soehnlein, Oliver; Zarzycka, Barbara; Aarts, Suzanne A. B. M.; Lameijer, Marnix; Gijbels, Marion J.; Beckers, Linda; Toom, Myrthe den; Slutter, Bram; Kuiper, Johan; Duchene, Johan; Aslani, Maria; Megens, Remco T. A.; Veer, Cornelis van 't; Kooij, Gijs; Schrijver, Roy; Hoeksema, Marten A.; Boon, Louis; Fay, Francois; Tang, Jun; Baxter, Samantha; Jongejan, Aldo; Moerland, Perry D.; Vriend, Gert; Bleijlevens, Boris; Fisher, Edward A.; Duivenvoorden, Raphael; Gerdes, Norbert; Winther, Menno P. J. de; Nicolaes, Gerry A.; Mulder, Willem J. M.; Weber, Christian und Lutgens, Esther
(2018):
Targeting CD40-Induced TRAF6 Signaling in Macrophages Reduces Atherosclerosis.
In: Journal of the American College of Cardiology, Bd. 71, Nr. 5: S. 527-542
Neele, Annette E.; Gijbels, Marion J. J.; Velden, Saskia van der; Hoeksema, Marten A.; Boshuizen, Marieke C. S.; Prange, Koen H. M.; Chen, Hung-Jen; Bossche, Jan van den; Roomen, Cindy P. P. A. van; Shami, Annelie; Levels, Johannes H. M.; Kroon, Jeffrey; Lucas, Tina; Dimmeler, Stefanie; Lutgens, Esther und Winther, Menno P. J. de
(2018):
Myeloid Kdm6b deficiency results in advanced atherosclerosis.
In: Atherosclerosis, Bd. 275: S. 156-165
Tuin, Sam J. L. van der; Li, Zhuang; Berbee, Jimmy F. P.; Verkouter, Inge; Ringnalda, Linda E.; Neele, Annette E.; Klinken, Jan B. van; Rensen, Sander S.; Fu, Jingyuan; Winther, Menno P. J. de; Groen, Albert K.; Rensen, Patrick C. N.; Willems van Dijk, Ko und Wang, Yanan
(2018):
Lipopolysaccharide Lowers Cholesteryl Ester Transfer Protein by Activating F4/80(+)Clec4f(+)Vsig4(+)Ly6C(-) Kupffer Cell Subsets.
In: Journal of the American Heart Association, Bd. 7, Nr. 6, e008105
Baardman, Jeroen; Verberk, Sanne G. S.; Prange, Koen H. M.; Weeghel, Michel van; Velden, Saskia van der; Ryan, Dylan G.; Wust, Rob C. I.; Neele, Annette E.; Speijer, Dave; Denis, Simone W.; Witte, Maarten E.; Houtkooper, Riekelt H.; O'Neill, Luke A.; Knatko, Elena V.; Dinkova-Kostova, Albena T.; Lutgens, Esther; Winther, Menno P. J. de und Bossche, Jan van den
(2018):
A Defective Pentose Phosphate Pathway Reduces Inflammatory Macrophage Responses during Hypercholesterolemia.
In: Cell Reports, Bd. 25, Nr. 8: S. 2044-2052
Vorst, Emiel P. C. van der; Theodorou, Kosta; Wu, Yongzheng; Hoeksema, Marten A.; Goossens, Pieter; Bursill, Christina A.; Aliyev, Taghi; Huitema, Leonie F. A.; Tas, Sander W.; Wolfs, Ine M. J.; Kuijpers, Marijke J. E.; Gijbels, Marion J.; Schalkwijk, Casper G.; Koonen, Debby P. Y.; Abdollahi-Roodsaz, Shahla; McDaniels, Kimberly; Wang, Chih-Chieh; Leitges, Michael; Lawrence, Toby; Plat, Jogchum; Eck, Miranda van; Rye, Kerry-Anne; Touqui, Lhousseine; Winther, Menno P. J. de; Biessen, Erik A. L. und Donners, Marjo M. P. C.
(2017):
High-Density Lipoproteins Exert Pro-inflammatory Effects on Macrophages via Passive Cholesterol Depletion and PKC-NF-kappa B/STAT1-IRF1 Signaling.
In: Cell Metabolism, Bd. 25, Nr. 1: S. 197-207
Berg, Susan M. van den; Dam, Andrea D. van; Rensen, Patrick C. N.; Winther, Menno P. J. de und Lutgens, Esther
(2017):
Immune Modulation of Brown(ing) Adipose Tissue in Obesity.
In: Endocrine Reviews, Bd. 38, Nr. 1: S. 46-68
Beldman, Thijs J.; Senders, Max L.; Alaarg, Amr; Perez-Medina, Carlos; Tang, Jun; Zhao, Yiming; Fay, Francois; Deichmöller, Jacqueline; Born, Benjamin; Desclos, Emilie; Wel, Nicole N. van der; Höbe, Ron A.; Kohen, Fortune; Kartvelishvily, Elena; Neeman, Michal; Reiner, Thomas; Calcagno, Claudia; Fayad, Zahi A.; Winther, Menno P. J. de; Lutgens, Esther; Mulder, Willem J. M. und Kluza, Ewelina
(2017):
Hyaluronan Nanoparticles Selectively Target Plaque-Associated Macrophages and Improve Plaque Stability in Atherosclerosis.
In: Acs Nano, Bd. 11, Nr. 6: S. 5785-5799
Neele, Annette E.; Prange, Koen H. M.; Hoeksema, Marten A.; Velden, Saskia van der; Lucas, Tina; Dimmeler, Stefanie; Lutgens, Esther; Bossche, Jan van den und Winther, Menno P. J. de
(2017):
Macrophage Kdm6b controls the profibrotic transcriptome signature of foam cells.
In: Epigenomics, Bd. 9, Nr. 4: S. 383-391
Ahmed, Mohamed; Winther, Menno P. J. de und Bossche, Jan van den
(2017):
Epigenetic mechanisms of macrophage activation in type 2 dilabetes.
In: Immunobiology, Bd. 222, Nr. 10: S. 937-943
Berg, Susan M. van den; Dam, Andrea D. van; Kusters, Pascal J. H.; Beckers, Linda; Toom, Myrthe den; Velden, Saskia van der; Bossche, Jan van den; Die, Irma van; Boon, Mariette R.; Rensen, Patrick C. N.; Lutgens, Esther und Winther, Menno P. J. de
(2017):
Helminth antigens counteract a rapid high-fat diet-induced decrease in adipose tissue eosinophils.
In: Journal of Molecular Endocrinology, Bd. 59, Nr. 3: S. 245-255
Asare, Yaw; Ommer, Miriam; Azombo, Florence. A.; Alampour-Rajabi, Setareh; Sternkopf, Marieke; Sanati, Maryam; Gijbels, Marion J.; Schmitz, Corinna; Sinitski, Dzmitry; Tilstam, Pathricia V.; Lue, Hongqi; Gessner, Andre; Lange, Denise; Schmid, Johannes A.; Weber, Christian; Dichgans, Martin; Jankowski, Joachim; Pardi, Ruggero; Winther, Menno P. J. de; Nöls, Heidi und Bernhagen, Jürgen
(2017):
Inhibition of atherogenesis by the COP9 signalosome subunit 5 in vivo.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 114, Nr. 13, E2766-E2775
Tilstam, Pathricia V.; Theelen, Wendy; Alampour-Sarabi, Setareh; Pawig, Lukas; Asare, Yaw; Döring, Yvonne; Winther, Menno P. J. de; Lawrence, Toby; Zernecke, Alma; Bernhagen, Jürgen; Schober, Andreas; Jankowski, Joachim; Weber, Christian und Noels, Heidi
(2016):
Non-activatable mutant of inhibitor of kappa b kinase α (ikk α) exerts site-specific effects on atherosclerosis.
In: Nephrology Dialysis Transplantation, Bd. 31: S. 48
Berg, Susan M. van den; Seijkens, Tom T. P.; Kusters, Pascal J. H.; Beckers, Linda; Toom, Myrthe; den Smeets, Esther; Levels, Johannes; Winther, Menno P. J. de und Lutgens, Esther
(2016):
Diet-induced obesity in mice diminishes hematopoietic stem and progenitor cells in the bone marrow.
In: FASEB Journal, Bd. 30, Nr. 5: S. 1779-1788
Dam, Andrea D. van; Bekkering, Siroon; Crasborn, Malou; Beek, Lianne van; Berg, Susan M. van den; Vrieling, Frank; Joosten, Simone A.; Harmelen, Vanessa van; Winther, Menno P. J. de; Lütjohann, Dieter; Lutgens, Esther; Boon, Mariëtte R.; Riksen, Niels P.; Rensen, Patrick C. N. und Berbée, Jimmy F. P.
(2016):
BCG lowers plasma cholesterol levels and delays atherosclerotic lesion progression in mice.
In: Atherosclerosis, Bd. 251: S. 6-14
Boshuizen, Marieke C. S.; Hoeksema, Marten A.; Neele, Annette E.; Velden, Saskia van der; Hamers, Anouk A. J.; Bossche, Jan Van den; Lutgens, Esther und Winther, Menno P. J. de
(2016):
Interferon-beta promotes macrophage foam cell formation by altering both cholesterol influx and efflux mechanisms.
In: Cytokine, Bd. 77: S. 220-226
Hoeksema, Marten A.; Gijbels, Marion J. J.; Bossche, Jan van den; Velden, Saskia van der; Sijm, Ayestha; Neele, Annette E.; Seijkens, Tom; Stöger, Lauran J.; Meiler, Svenja; Boshuizen, Marieke C. S.; Dallinga-Thie, Geesje M.; Levels, Johannes H. M.; Boon, Louis; Mullican, Shannon E.; Spann, Nathanael J.; Cleutjens, Jack P.; Glass, Chris K.; Lazar, Mitchell A.; Vries, Carlie J. M. de; Biessen, Erik A. L.; Daemen, Mat J. A. P.; Lutgens, Esther und Winther, Menno P. J. de
(2014):
Targeting macrophage Histone deacetylase 3 stabilizes atherosclerotic lesions.
In: Embo Molecular Medicine, Bd. 6, Nr. 9: S. 1124-1132
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