Anzahl der Publikationen: 13
Zeitschriftenartikel
Greif, Philipp A.; Hartmann, Luise; Vosberg, Sebastian; Stief, Sophie M.; Mattes, Raphael; Hellmann, Ines; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Kerbs, Paul; Jurinovic, Vindi; Schumacher, Daniela; Pastore, Friederike; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Neumann, Martin; Baldus, Claudia D.; Bohlander, Stefan K.; Wolf, Stephan; Görlich, Dennis; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Hiddemann, Wolfgang und Spiekermann, Karsten
(2018):
Evolution of Cytogenetically Normal Acute Myeloid Leukemia During Therapy and Relapse: An Exome Sequencing Study of 50 Patients.
In: Clinical Cancer Research, Bd. 24, Nr. 7: S. 1716-1726
Rothenberg-Thurley, Maja; Amler, Susanne; Goerlich, Dennis; Köhnke, Thomas; Konstandin, Nikola P.; Schneider, Stephanie; Sauerland, Maria C.; Herold, Tobias; Hubmann, Max; Ksienzyk, Bianka; Zellmeier, Evelyn; Bohlander, Stefan K.; Subklewe, Marion; Faldum, Andreas; Hiddemann, Wolfgang; Braess, Jan; Spiekermann, Karsten und Metzeler, Klaus H.
(2018):
Persistence of pre-leukemic clones during first remission and risk of relapse in acute myeloid leukemia.
In: Leukemia, Bd. 32, Nr. 7: S. 1598-1608
Herold, Tobias; Schneider, S.; Metzeler, Klaus H.; Neumann, Martin; Hartmann, Luise; Roberts, Kathryn G.; Konstandin, Nikola P.; Greif, Philipp A.; Bräundl, Kathrin; Ksienzyk, Bianka; Huk, Natalia; Schneider, Irene; Zellmeier, Evelyn; Jurinovic, Vindi; Mansmann, Ulrich; Hiddemann, Wolfgang; Mullighan, Charles G.; Bohlander, Stefan K.; Spiekermann, Karsten; Hölzel, Dieter; Brüggemann, Monika; Baldus, Claudia D.; Dreyling, Martin und Gökbuget, Nicola
(2017):
Adults with Philadelphia chromosome–like acute lymphoblastic leukemia frequently have IGH-CRLF2 and JAK2 mutations, persistence of minimal residual disease and poor prognosis.
In: Haematologica, Bd. 102, Nr. 1: S. 130-138
[PDF, 1MB]
Herold, Tobias; Metzeler, Klaus H.; Vosberg, Sebastian; Hartmann, Luise; Jurinovic, Vindi; Opatz, Sabrina; Konstandin, Nikola P.; Schneider, S.; Zellmeier, Evelyn; Ksienzyk, Bianka; Graf, A.; Krebs, S.; Blum, H.; Sauerland, Maria Cristina; Büchner, T.; Berdel, W. E.; Wörmann, Bernhard; Mansmann, Ulrich; Hiddemann, Wolfgang; Bohlander, Stefan K.; Spiekermann, Karsten und Greif, Philipp A.
(2017):
Acute Myeloid Leukemia with Del(9q) is Characterized by Frequent Mutations of NPM1, DNMT3A, WT1 and Low Expression of TLE4.
In: Genes, Chromosomes and Cancer, Bd. 56, Nr. 1: S. 75-86
Sandhöfer, Nadine; Bauer, Julia; Reiter, Katrin; Dufour, Annika; Rothenberg, Maja; Konstandin, Nikola P.; Zellmeier, Evelyn; Tizazu, Belay; Greif, Philipp A.; Metzeler, Klaus H.; Hiddemann, Wolfgang; Polzer, Harald und Spiekermann, Karsten
(2016):
The new and recurrent FLT3 juxtamembrane deletion mutation shows a dominant negative effect on the wild-type FLT3 receptor.
In: Scientific Reports, Bd. 6, 28032
[PDF, 846kB]
Hartmann, Luise; Dutta, Sayantanee; Opatz, Sabrina; Vosberg, Sebastian; Reiter, Katrin; Leubolt, Georg; Metzeler, Klaus H.; Herold, Tobias; Bamopoulos, Stefanos A.; Bräundl, Kathrin; Zellmeier, Evelyn; Ksienzyk, Bianka; Konstandin, Nikola P.; Schneider, Stephanie; Hopfner, Karl-Peter; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Middeke, Jan Moritz; Stölzel, Friedrich; Thiede, Christian; Wolf, Stephan; Bohlander, Stefan K.; Preiss, Caroline; Chen-Wichmann, Linping; Wichmann, Christian; Sauerland, Maria Cristina; Büchner, Thomas; Berdel, Wolfgang E.; Wörmann, Bernhard J.; Braess, Jan; Hiddemann, Wolfgang; Spiekermann, Karsten und Greif, Philipp A.
(2016):
ZBTB7A mutations in acute myeloid leukaemia with t(8;21) translocation.
In: Nature Communications, Bd. 7, 11733
[PDF, 1MB]
Metzeler, Klaus H.; Herold, Tobias; Rothenberg-Thurley, Maja; Amler, Susanne; Sauerland, Maria C.; Görlich, Dennis; Schneider, Stephanie; Konstandin, Nikola P.; Dufour, Annika; Bräundl, Kathrin; Ksienzyk, Bianka; Zellmeier, Evelyn; Hartmann, Luise; Greif, Philipp A.; Fiegl, Michael; Subklewe, Marion; Bohlander, Stefan K.; Krug, Utz; Faldum, Andreas; Berdel, Wolfgang E.; Wörmann, Bernhard; Büchner, Thomas; Hiddemann, Wolfgang; Braess, Jan und Spiekermann, Karsten
(2016):
Spectrum and prognostic relevance of driver gene mutations in acute myeloid leukemia.
In: Blood, Bd. 128, Nr. 5: S. 686-698
Pastore, Friederike; Greif, Philipp A.; Schneider, Stephanie; Ksienzyk, Bianka; Mellert, Gudrun; Zellmeier, Evelyn; Braess, Jan; Sauerland, Cristina M.; Heinecke, Achim; Krug, Utz; Berdel, Wolfgang E.; Buechner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
The NPM1 Mutation Type Has No Impact on Survival in Cytogenetically Normal AML.
In: PLOS ONE
9(10), e109759
[PDF, 605kB]
Hubmann, Max; Köhnke, Thomas; Hoster, Eva; Schneider, Stephanie; Dufour, Annika; Zellmeier, Evelyn; Fiegl, Michael; Braess, Jan; Bohlander, Stefan K.; Subklewe, Marion; Sauerland, Maria-Cristina; Berdel, Wolfgang E.; Büchner, Thomas; Woermann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2014):
Molecular response assessment by quantitative real-time polymerase chain reaction after induction therapy in NPM1-mutated patients identifies those at high risk of relapse.
In: Haematologica, Bd. 99, Nr. 8: S. 1317-1325
[PDF, 838kB]
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Kakadia, P. M.; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2012):
The FLT3ITD level has a high prognostic impact in NPM1 mutated, but not NPM1 unmutated AML with a normal karyotype.
In: Blood, Bd. 119, Nr. 19: S. 4383-4386
Greif, Philipp A.; Dufour, A.; Konstandin, Nikola P.; Ksienzyk, Bianka; Zellmeier, Evelyn; Tizazu, B.; Sturm, J.; Benthaus, T.; Herold, Tobias; Yaghmaie, M.; Dorge, P.; Hopfner, K. P.; Hauser, A.; Graf, A.; Krebs, S.; Blum, H.; Kakadia, P. M.; Schneider, S.; Hoster, Eva; Schneider, F.; Stanulla, M.; Braess, J.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang; Spiekermann, Karsten und Bohlander, Stefan K.
(2012):
GATA2 zinc finger 1 mutations associated with biallelic CEBPA mutations define a unique genetic entity of acute myeloid leukemia.
In: Blood, Bd. 120, Nr. 2: S. 395-403
Dufour, A.; Schneider, F.; Metzeler, Klaus H.; Hoster, Eva; Schneider, S.; Zellmeier, Evelyn; Benthaus, T.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Braess, J.; Hiddemann, Wolfgang; Bohlander, Stefan K. und Spiekermann, Karsten
(2010):
Acute myeloid leukemia with biallelic CEBPA gene mutations and normal karyotype represents a distinct genetic entity associated with a favorable clinical outcome.
In: Journal of Clinical Oncology, Bd. 28, Nr. 4: S. 570-577
Schneider, F.; Hoster, Eva; Unterhalt, Michael; Schneider, S.; Dufour, A.; Benthaus, T.; Mellert, G.; Zellmeier, Evelyn; Bohlander, Stefan K.; Feuring-Buske, M.; Buske, C.; Braess, J.; Fritsch, S.; Heinecke, A.; Sauerland, M. C.; Berdel, W. E.; Büchner, T.; Wörmann, Bernhard; Hiddemann, Wolfgang und Spiekermann, Karsten
(2009):
NPM1, but not FLT3-ITD mutations predict early blast cell clearance and CR rate in patients with normal karyotype AML (NK-AML) or high risk myelodysplastic syndrome (MDS).
In: Blood, Bd. 113, Nr. 21: S. 5250-5253
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