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Anzahl der Publikationen: 16
Zeitschriftenartikel
Shojaei, Monireh; Zhou, Qihui; Palumbo, Giovanna; Schaefer, Rebecca; Kaskinoro, Janne; Vehmaan-Kreula, Pirjo; Bartenstein, Peter; Brendel, Matthias 
ORCID: https://orcid.org/0000-0002-9247-2843; Edbauer, Dieter und Lindner, Simon ORCID: https://orcid.org/0009-0007-4379-4436
(2024):
Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
In: ACS Pharmacology & Translational Science, Bd. 7, Nr. 5: S. 1404-1414
[PDF, 8MB]
ORCID: https://orcid.org/0000-0002-9247-2843; Edbauer, Dieter und Lindner, Simon ORCID: https://orcid.org/0009-0007-4379-4436
(2024):
Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
In: ACS Pharmacology & Translational Science, Bd. 7, Nr. 5: S. 1404-1414
[PDF, 8MB]
Caldi Gomes, Lucas ORCID: https://orcid.org/0000-0003-4959-2169; Hänzelmann, Sonja ORCID: https://orcid.org/0000-0003-4953-0101; Hausmann, Fabian ORCID: https://orcid.org/0000-0001-6110-5824; Khatri, Robin ORCID: https://orcid.org/0009-0006-5311-1718; Oller, Sergio; Parvaz, Mojan; Tzeplaeff, Laura ORCID: https://orcid.org/0009-0003-7643-3232; Pasetto, Laura; Gebelin, Marie; Ebbing, Melanie; Holzapfel, Constantin; Columbro, Stefano Fabrizio; Scozzari, Serena; Knöferle, Johanna; Cordts, Isabell; Demleitner, Antonia F.; Deschauer, Marcus; Dufke, Claudia; Sturm, Marc; Zhou, Qihui; Zelina, Pavol; Sudria-Lopez, Emma; Haack, Tobias B. ORCID: https://orcid.org/0000-0001-6033-4836; Streb, Sebastian ORCID: https://orcid.org/0000-0002-9095-6596; Kuzma-Kozakiewicz, Magdalena; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Pasterkamp, R. Jeroen ORCID: https://orcid.org/0000-0003-1631-6440; Laczko, Endre ORCID: https://orcid.org/0000-0003-0271-3971; Rehrauer, Hubert ORCID: https://orcid.org/0000-0001-7612-9394; Schlapbach, Ralph; Carapito, Christine ORCID: https://orcid.org/0000-0002-0079-319X; Bonetto, Valentina ORCID: https://orcid.org/0000-0003-0456-2054; Bonn, Stefan und Lingor, Paul
(2024):
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target.
In: Nature Communications, Bd. 15, 4893
[PDF, 4MB]
ORCID: https://orcid.org/0000-0003-4959-2169; Hänzelmann, Sonja ORCID: https://orcid.org/0000-0003-4953-0101; Hausmann, Fabian ORCID: https://orcid.org/0000-0001-6110-5824; Khatri, Robin ORCID: https://orcid.org/0009-0006-5311-1718; Oller, Sergio; Parvaz, Mojan; Tzeplaeff, Laura ORCID: https://orcid.org/0009-0003-7643-3232; Pasetto, Laura; Gebelin, Marie; Ebbing, Melanie; Holzapfel, Constantin; Columbro, Stefano Fabrizio; Scozzari, Serena; Knöferle, Johanna; Cordts, Isabell; Demleitner, Antonia F.; Deschauer, Marcus; Dufke, Claudia; Sturm, Marc; Zhou, Qihui; Zelina, Pavol; Sudria-Lopez, Emma; Haack, Tobias B. ORCID: https://orcid.org/0000-0001-6033-4836; Streb, Sebastian ORCID: https://orcid.org/0000-0002-9095-6596; Kuzma-Kozakiewicz, Magdalena; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Pasterkamp, R. Jeroen ORCID: https://orcid.org/0000-0003-1631-6440; Laczko, Endre ORCID: https://orcid.org/0000-0003-0271-3971; Rehrauer, Hubert ORCID: https://orcid.org/0000-0001-7612-9394; Schlapbach, Ralph; Carapito, Christine ORCID: https://orcid.org/0000-0002-0079-319X; Bonetto, Valentina ORCID: https://orcid.org/0000-0003-0456-2054; Bonn, Stefan und Lingor, Paul
(2024):
Multiomic ALS signatures highlight subclusters and sex differences suggesting the MAPK pathway as therapeutic target.
In: Nature Communications, Bd. 15, 4893
[PDF, 4MB]
Calbiac, Hortense de ORCID: https://orcid.org/0000-0002-6246-0833; Renault, Solène; Haouy, Grégoire; Jung, Vincent; Roger, Kevin; Zhou, Qihui; Campanari, Maria-Letizia; Chentout, Loïc; Demy, Doris Lou; Marian, Anca; Goudin, Nicolas; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Guerrera, Chiara; Ciura, Sorana und Kabashi, Edor
(2024):
Poly-GP accumulation due to C9orf72 loss of function induces motor neuron apoptosis through autophagy and mitophagy defects.
In: Autophagy, Bd. 20, Nr. 10: S. 2164-2185
[PDF, 5MB]
ORCID: https://orcid.org/0000-0002-6246-0833; Renault, Solène; Haouy, Grégoire; Jung, Vincent; Roger, Kevin; Zhou, Qihui; Campanari, Maria-Letizia; Chentout, Loïc; Demy, Doris Lou; Marian, Anca; Goudin, Nicolas; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Guerrera, Chiara; Ciura, Sorana und Kabashi, Edor
(2024):
Poly-GP accumulation due to C9orf72 loss of function induces motor neuron apoptosis through autophagy and mitophagy defects.
In: Autophagy, Bd. 20, Nr. 10: S. 2164-2185
[PDF, 5MB]
Hausmann, Fabian ORCID: https://orcid.org/0000-0001-6110-5824; Caldi Gomes, Lucas ORCID: https://orcid.org/0000-0003-4959-2169; Hänzelmann, Sonja ORCID: https://orcid.org/0000-0003-4953-0101; Khatri, Robin ORCID: https://orcid.org/0009-0006-5311-1718; Oller, Sergio ORCID: https://orcid.org/0000-0002-8994-1549; Gebelin, Marie ORCID: https://orcid.org/0009-0001-4696-3799; Parvaz, Mojan ORCID: https://orcid.org/0000-0002-0644-5559; Tzeplaeff, Laura ORCID: https://orcid.org/0009-0003-7643-3232; Pasetto, Laura ORCID: https://orcid.org/0000-0003-0319-4448; Zhou, Qihui ORCID: https://orcid.org/0000-0001-5733-9820; Zelina, Pavol ORCID: https://orcid.org/0009-0008-6776-663X; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Pasterkamp, R Jeroen ORCID: https://orcid.org/0000-0003-1631-6440; Rehrauer, Hubert ORCID: https://orcid.org/0000-0001-7612-9394; Schlapbach, Ralph ORCID: https://orcid.org/0000-0002-7488-4262; Carapito, Christine ORCID: https://orcid.org/0000-0002-0079-319X; Bonetto, Valentina ORCID: https://orcid.org/0000-0003-0456-2054; Bonn, Stefan ORCID: https://orcid.org/0000-0003-4366-5662 und Lingor, Paul ORCID: https://orcid.org/0000-0001-9362-7096
(2024):
A dataset profiling the multiomic landscape of the prefrontal cortex in amyotrophic lateral sclerosis.
In: GigaScience, Bd. 13, Nr. giae100
[PDF, 3MB]
ORCID: https://orcid.org/0000-0001-6110-5824; Caldi Gomes, Lucas ORCID: https://orcid.org/0000-0003-4959-2169; Hänzelmann, Sonja ORCID: https://orcid.org/0000-0003-4953-0101; Khatri, Robin ORCID: https://orcid.org/0009-0006-5311-1718; Oller, Sergio ORCID: https://orcid.org/0000-0002-8994-1549; Gebelin, Marie ORCID: https://orcid.org/0009-0001-4696-3799; Parvaz, Mojan ORCID: https://orcid.org/0000-0002-0644-5559; Tzeplaeff, Laura ORCID: https://orcid.org/0009-0003-7643-3232; Pasetto, Laura ORCID: https://orcid.org/0000-0003-0319-4448; Zhou, Qihui ORCID: https://orcid.org/0000-0001-5733-9820; Zelina, Pavol ORCID: https://orcid.org/0009-0008-6776-663X; Edbauer, Dieter ORCID: https://orcid.org/0000-0002-7186-4653; Pasterkamp, R Jeroen ORCID: https://orcid.org/0000-0003-1631-6440; Rehrauer, Hubert ORCID: https://orcid.org/0000-0001-7612-9394; Schlapbach, Ralph ORCID: https://orcid.org/0000-0002-7488-4262; Carapito, Christine ORCID: https://orcid.org/0000-0002-0079-319X; Bonetto, Valentina ORCID: https://orcid.org/0000-0003-0456-2054; Bonn, Stefan ORCID: https://orcid.org/0000-0003-4366-5662 und Lingor, Paul ORCID: https://orcid.org/0000-0001-9362-7096
(2024):
A dataset profiling the multiomic landscape of the prefrontal cortex in amyotrophic lateral sclerosis.
In: GigaScience, Bd. 13, Nr. giae100
[PDF, 3MB]
Riemenschneider, Henrick; Simonetti, Francesca; Sheth, Udit; Katona, Eszter; Roth, Stefan; Hutten, Saskia; Farny, Daniel; Michaelsen, Meike; Nuscher, Brigitte; Schmidt, Michael K.; Flatley, Andrew; Schepers, Aloys; da Silva, Lara Gruijs A.; Zhou, Qihui; Klopstock, Thomas; Liesz, Arthur; Arzberger, Thomas; Herms, Jochen; Feederle, Regina; Gendron, Tania F.; Dormann, Dorothee und Edbauer, Dieter
(2023):
Targeting the glycine-rich domain of TDP-43 with antibodies prevents its aggregation in vitro and reduces neurofilament levels in vivo.
In: Acta Neuropathologica Communications, Bd. 11, Nr. 1, 112
[PDF, 6MB]
Czuppa, Mareike; Dhingra, Ashutosh; Zhou, Qihui; Schludi, Carina; Koenig, Laura; Scharf, Elisabeth; Farny, Daniel; Dalmia, Anupriya; Taeger, Joachim; Castillo-Lizardo, Melissa; Katona, Eszter; Mori, Kohji; Aumer, Tina; Schelter, Florian; Mueller, Markus; Carell, Thomas; Kalliokoski, Tuomo; Messinger, Josef; Rizzu, Patrizia; Heutink, Peter und Edbauer, Dieter
(2022):
Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G(4)C(2))(n) expression in C9orf72 ALS/FTD.
In: Cell Reports, Bd. 39, Nr. 10, 110913
[PDF, 3MB]
Heindl, Steffanie; Ricci, Alessio; Carofiglio, Olga; Zhou, Qihui; Arzberger, Thomas; Lenart, Nikolett; Franzmeier, Nicolai; Hortobagyi, Tibor; Nelson, Peter T.; Stowe, Ann M.; Denes, Adam; Edbauer, Dieter und Liesz, Arthur
(2021):
Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
In: Journal of Experimental Medicine, Bd. 218, Nr. 8, e20202411
[PDF, 3MB]
Wagner, Matias; Lorenz, Georg; Volk, Alexander E.; Brunet, Theresa; Edbauer, Dieter; Berutti, Riccardo; Zhao, Chen; Anderl-Straub, Sarah; Bertram, Lars; Danek, Adrian ORCID: https://orcid.org/0000-0001-8857-5383; Deschauer, Marcus; Dill, Veronika; Fassbender, Klaus; Fliessbach, Klaus; Goetze, Katharina S.; Jahn, Holger; Kornhuber, Johannes; Landwehrmeyer, Bernhard; Lauer, Martin; Obrig, Hellmuth; Prudlo, Johannes; Schneider, Anja; Schroeter, Matthias L.; Uttner, Ingo; Vukovich, Ruth; Wiltfang, Jens; Winkler, Andrea S.; Zhou, Qihui; Ludolph, Albert C.; Oexle, Konrad; Otto, Markus; Diehl-Schmid, Janine und Winkelmann, Juliane
(2021):
Clinico-genetic findings in 509 frontotemporal dementia patients.
In: Molecular Psychiatry, Bd. 26, Nr. 10: S. 5824-5832
[PDF, 1MB]
ORCID: https://orcid.org/0000-0001-8857-5383; Deschauer, Marcus; Dill, Veronika; Fassbender, Klaus; Fliessbach, Klaus; Goetze, Katharina S.; Jahn, Holger; Kornhuber, Johannes; Landwehrmeyer, Bernhard; Lauer, Martin; Obrig, Hellmuth; Prudlo, Johannes; Schneider, Anja; Schroeter, Matthias L.; Uttner, Ingo; Vukovich, Ruth; Wiltfang, Jens; Winkler, Andrea S.; Zhou, Qihui; Ludolph, Albert C.; Oexle, Konrad; Otto, Markus; Diehl-Schmid, Janine und Winkelmann, Juliane
(2021):
Clinico-genetic findings in 509 frontotemporal dementia patients.
In: Molecular Psychiatry, Bd. 26, Nr. 10: S. 5824-5832
[PDF, 1MB]
LaClair, Katherine D.; Zhou, Qihui; Michaelsen, Meike; Wefers, Benedikt; Brill, Monika S.; Janjic, Aleksandar; Rathkolb, Birgit; Farny, Daniel; Cygan, Mikolaj; de Angelis, Martin Hrabe; Wurst, Wolfgang; Neumann, Manuela; Enard, Wolfgang; Misgeld, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2020):
Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 121-142
[PDF, 8MB]
Khosravi, Bahram; LaClair, Kathrine D.; Riemenschneider, Henrick; Zhou, Qihui; Frottin, Frederic; Mareljic, Nikola; Czuppa, Mareike; Farny, Daniel; Hartmann, Hannelore; Michaelsen, Meike; Arzberger, Thomas; Hartl, F. Ulrich; Hipp, Mark S. und Edbauer, Dieter
(2020):
Cell-to-cell transmission of C9orf72 poly-(Gly-Ala) triggers key features of ALS/FTD.
In: EMBO Journal, Bd. 39, Nr. 8, e102811
[PDF, 2MB]
Zhou, Qihui; Mareljic, Nikola; Michaelsen, Meike; Parhizkar, Samira; Heindl, Steffanie; Nuscher, Brigitte; Farny, Daniel; Czuppa, Mareike; Schludi, Carina; Graf, Alexander; Krebs, Stefan; Blum, Helmut; Feederle, Regina; Roth, Stefan; Haass, Christian; Arzberger, Thomas; Liesz, Arthur und Edbauer, Dieter
(2019):
Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
In: EMBO Molecular Medicine, e10919
[PDF, 969kB]
Nihei, Yoshihiro; Mori, Kohji; Werner, Georg; Arzberger, Thomas; Zhou, Qihui; Khosravi, Barham; Japtok, Julia; Hermann, Andreas; Sommacal, Andreas; Weber, Markus; Kamp, Frits; Nuscher, Brigitte; Edbauer, Dieter und Haass, Christian
(2019):
Poly-glycine-alanine exacerbates C9orf72 repeat expansion-mediated DNA damage via sequestration of phosphorylated ATM and loss of nuclear hnRNPA3.
In: Acta Neuropathologica, Bd. 139, Nr. 1: S. 99-118
[PDF, 3MB]
Schludi, Martin H.; Becker, Lore; Garrett, Lillian; Gendron, Tania F.; Zhou, Qihui; Schreiber, Franziska; Popper, Bastian; Dimou, Leda; Strom, Tim M.; Winkelmann, Juliane; Thaden, Anne von; Rentzsch, Kristin; May, Stephanie; Michaelsen, Meike; Schwenk, Benjamin M.; Tan, Jing; Schoser, Benedikt; Dieterich, Marianne; Petrucelli, Leonard; Hölter, Sabine M.; Wurst, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Klopstock, Thomas; Arzberger, Thomas und Edbauer, Dieter
(2017):
Spinal poly-GA inclusions in a C9orf72 mouse model trigger motor deficits and inflammation without neuron loss.
In: Acta Neuropathologica, Bd. 134, Nr. 2: S. 241-254
Zhou, Qihui; Lehmer, Carina; Michaelsen, Meike; Mori, Kohji; Alterauge, Dominik; Baumjohann, Dirk; Schludi, Martin H.; Greiling, Johanna; Farny, Daniel; Flatley, Andrew; Feederle, Regina; May, Stephanie; Schreiber, Franziska; Arzberger, Thomas; Kuhm, Christoph; Klopstock, Thomas; Hermann, Andreas; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627 und Edbauer, Dieter
(2017):
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702
ORCID: https://orcid.org/0000-0002-4869-1627 und Edbauer, Dieter
(2017):
Antibodies inhibit transmission and aggregation of C9orf72 poly-GA dipeptide repeat proteins.
In: Embo Molecular Medicine, Bd. 9, Nr. 5: S. 687-702
Mori, Kohji; Nihei, Yoshihiro; Arzberger, Thomas; Zhou, Qihui; Mackenzie, Ian R.; Hermann, Andreas; Hanisch, Frank; Kamp, Frits; Nuscher, Brigitte; Orozco, Denise; Edbauer, Dieter und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.
In: Embo Reports, Bd. 17, Nr. 9: S. 1314-1325
ORCID: https://orcid.org/0000-0002-4869-1627
(2016):
Reduced hnRNPA3 increases C9orf72 repeat RNA levels and dipeptide-repeat protein deposition.
In: Embo Reports, Bd. 17, Nr. 9: S. 1314-1325
Zhou, Qihui; Haupt, Sonja; Kreuzer, Johannes T.; Hammitzsch, Ariane; Proft, Fabian; Neumann, Carla; Leipe, Jan; Witt, Matthias; Schulze-Koops, Hendrik und Skapenko, Alla
(2015):
Decreased expression of miR-146a and miR-155 contributes to an abnormal Treg phenotype in patients with rheumatoid arthritis.
In: Annals of the rheumatic diseases, Bd. 74, Nr. 6: S. 1265-1274
[PDF, 2MB]