ORCID: https://orcid.org/0000-0002-0654-387X; Donnan, Geoffrey; Esposito, Elga; Foster, Russell; Howells, David W.; Huang, Yi-Ge; Ji, Xunming; Klerman, Elizabeth B.; Lee, Sarah; Li, Wenlu; Liebeskind, David S.; Lizasoain, Ignacio; Mandeville, Emiri T.; Moro, Maria A.; Ning, MingMing; Ray, David; Sakadzic, Sava; Saver, Jeffrey L.; Scheer, Frank A. J. L.; Selim, Magdy; Tiedt, Steffen; Zhang, Fang and Buchan, Alastair M.
(2021):
Circadian Biology and Stroke.
In: Stroke, Vol. 52, No. 6: pp. 2180-2190
Abstract
Circadian biology modulates almost all aspects of mammalian physiology, disease, and response to therapies. Emerging data suggest that circadian biology may significantly affect the mechanisms of susceptibility, injury, recovery, and the response to therapy in stroke. In this review/perspective, we survey the accumulating literature and attempt to connect molecular, cellular, and physiological pathways in circadian biology to clinical consequences in stroke. Accounting for the complex and multifactorial effects of circadian rhythm may improve translational opportunities for stroke diagnostics and therapeutics.
| Item Type: | Journal article |
|---|---|
| Faculties: | Medicine Medicine > Munich Cluster for Systems Neurology (SyNergy) Medicine > Institute for Stroke and Dementia Research (ISD) |
| Subjects: | 600 Technology > 610 Medicine and health |
| ISSN: | 0039-2499 |
| Language: | English |
| Item ID: | 100201 |
| Date Deposited: | 05. Jun 2023, 15:34 |
| Last Modified: | 06. Jun 2024, 15:37 |
| DFG: | Gefördert durch die Deutsche Forschungsgemeinschaft (DFG) - 390857198 |
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