Anzahl der Publikationen auf dieser Ebene: 1809
2024
Afzali, Ali Maisam; Nirschl, Lucy; Sie, Christopher; Pfaller, Monika; Ulianov, Oleksii; Hassler, Tobias; Federle, Christine; Petrozziello, Elisabetta; Kalluri, Sudhakar Reddy; Chen, Hsin Hsiang; Tyystjaervi, Sofia; Muschaweckh, Andreas; Lammens, Katja; Delbridge, Claire; Buettner, Andreas; Steiger, Katja; Seyhan, Gonul; Ottersen, Ole Petter; Ollinger, Rupert; Rad, Roland; Jarosch, Sebastian; Straub, Adrian; Muehlbauer, Anton; Grassmann, Simon; Hemmer, Bernhard; Boettcher, Jan P.; Wagner, Ingrid; Kreutzfeldt, Mario; Merkler, Doron; Pardas, Irene Bonafonte; Supprian, Marc Schmidt; Buchholz, Veit R.; Heink, Sylvia; Busch, Dirk H.; Klein, Ludger und Korn, Thomas
(2024):
B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4.
In: Nature, Nr. 627: S. 407-415
[PDF, 11MB]
Aleo, Serena Jasmine; Dotto, Valentina Del; Romagnoli, Martina; Fiorini, Claudio; Capirossi, Giada; Peron, Camille; Maresca, Alessandra; Caporali, Leonardo; Capristo, Mariantonietta; Tropeano, Concetta Valentina; Zanna, Claudia; Ross-Cisneros, Fred N.; Sadun, Alfredo A.; Pignataro, Maria Gemma; Giordano, Carla; Fasano, Chiara; Cavaliere, Andrea; Porcelli, Anna Maria; Tioli, Gaia; Musiani, Francesco; Catania, Alessia; Lamperti, Costanza; Marzoli, Stefania Bianchi; Negri, Annamaria De; Cascavilla, Maria Lucia; Battista, Marco; Barboni, Piero; Carbonelli, Michele; Amore, Giulia; Morgia, Chiara La; Smirnov, Dmitrii; Vasilescu, Catalina; Farzeen, Aiman; Blickhaeuser, Beryll; Prokisch, Holger; Priglinger, Claudia; Livonius, Bettina; Catarino, Claudia B.; Klopstock, Thomas; Tiranti, Valeria; Carelli, Valerio und Maria, Anna
(2024):
Genetic variants affecting NQO1 protein levels impact the efficacy of idebenone treatment in Leber hereditary optic neuropathy.
In: Cell Reports Medicine, Bd. 5, Nr. 2, 101383
[PDF, 5MB]
Ancau, Miha; Tanti, Goutam Kumar; Butenschoen, Vicki Marie; Gempt, Jens; Yakushev, Igor; Nekolla, Stephan; Muehlau, Mark; Scheunemann, Christian; Heininger, Sebastian; Loewe, Benjamin; Loewe, Erik; Baer, Silke; Fischer, Johannes; Reiser, Judith; Ayachit, Sai S.; Liesche-Starnecker, Friederike; Schlegel, Juergen; Matiasek, Kaspar; Schifferer, Martina; Kirschke, Jan S.; Misgeld, Thomas; Lueth, Tim und Hemmer, Bernhard
(2024):
Validating a minipig model of reversible cerebral demyelination using human diagnostic modalities and electron microscopy.
In: Ebiomedicine, Bd. 100, 104982
[PDF, 4MB]
Assfalg, Marlene; Guener, Goekhan; Mueller, Stephan A.; Breimann, Stephan; Langosch, Dieter; Muhle-Goll, Claudia; Frishman, Dmitrij; Steiner, Harald und Lichtenthaler, Stefan F.
(2024):
Cleavage efficiency of the intramembrane protease γ-secretase is reduced by the palmitoylation of a substrate's transmembrane domain.
In: Faseb Journal, Bd. 38, Nr. 2, e23442
[PDF, 12MB]
Baeten, Paulien; Hamad, Ibrahim; Hoeks, Cindy; Hiltensperger, Michael; Wijmeersch, Bart Van; Popescu, Veronica; Aly, Lilian; Somers, Veerle; Korn, Thomas; Kleinewietfeld, Markus; Hellings, Niels und Broux, Bieke
(2024):
Rapamycin rescues loss of function in blood-brain barrier- interacting Tregs.
In: Jci Insight, Bd. 9, Nr. 7, e167457
[PDF, 6MB]
Baumeister, Hannah ORCID: https://orcid.org/0000-0001-5503-6308; Vogel, Jacob W. ORCID: https://orcid.org/0000-0001-6394-9940; Insel, Philip S. ORCID: https://orcid.org/0000-0002-6270-5490; Kleineidam, Luca; Wolfsgruber, Steffen; Stark, Melina; Gellersen, Helena M.; Yakupov, Renat ORCID: https://orcid.org/0000-0002-3868-284X; Schmid, Matthias C.; Lüsebrink, Falk; Brosseron, Frederic; Ziegler, Gabriel; Freiesleben, Silka D.; Preis, Lukas; Schneider, Luisa-Sophie; Spruth, Eike J.; Altenstein, Slawek; Lohse, Andrea; Fliessbach, Klaus; Vogt, Ina R; Bartels, Claudia; Schott, Björn H. ORCID: https://orcid.org/0000-0002-8237-4481; Rostamzadeh, Ayda; Glanz, Wenzel; Incesoy, Enise I.; Butryn, Michaela; Janowitz, Daniel; Rauchmann, Boris-Stephan; Kilimann, Ingo; Goerss, Doreen; Munk, Matthias H.; Hetzer, Stefan; Dechent, Peter; Ewers, Michael ORCID: https://orcid.org/0000-0001-5231-1714; Scheffler, Klaus; Wuestefeld, Anika; Strandberg, Olof; van Westen, Danielle ORCID: https://orcid.org/0000-0001-8649-9874; Mattsson-Carlgren, Niklas ORCID: https://orcid.org/0000-0002-8885-7724; Janelidze, Shorena; Stomrud, Erik; Palmqvist, Sebastian ORCID: https://orcid.org/0000-0002-9267-1930; Spottke, Annika; Laske, Christoph; Teipel, Stefan ORCID: https://orcid.org/0000-0002-3586-3194; Perneczky, Robert; Buerger, Katharina; Schneider, Anja; Priller, Josef; Peters, Oliver; Ramirez, Alfredo ORCID: https://orcid.org/0000-0003-4991-763X; Wiltfang, Jens; Heneka, Michael T.; Wagner, Michael; Düzel, Emrah ORCID: https://orcid.org/0000-0002-0139-5388; Jessen, Frank; Hansson, Oskar ORCID: https://orcid.org/0000-0001-8467-7286 und Berron, David ORCID: https://orcid.org/0000-0003-1558-1883
(2024):
A generalizable data-driven model of atrophy heterogeneity and progression in memory clinic settings.
In: Brain [Forthcoming]
[PDF, 1MB]
Bayas, Antonios ORCID: https://orcid.org/0000-0002-7418-9040; Mansmann, Ulrich ORCID: https://orcid.org/0000-0002-9955-8906; Ön, Begum Irmak; Hoffmann, Verena S.; Berthele, Achim; Mühlau, Mark; Kowarik, Markus C.; Krumbholz, Markus; Senel, Makbule; Steuerwald, Verena; Naumann, Markus; Hartberger, Julia; Kerschensteiner, Martin; Oswald, Eva; Ruschil, Christoph; Ziemann, Ulf; Tumani, Hayrettin; Vardakas, Ioannis; Albashiti, Fady; Kramer, Frank; Soto-Rey, Iñaki; Spengler, Helmut; Mayer, Gerhard; Kestler, Hans Armin; Kohlbacher, Oliver; Hagedorn, Marlien; Boeker, Martin; Kuhn, Klaus; Buchka, Stefan; Kohlmayer, Florian; Kirschke, Jan S.; Behrens, Lars; Zimmermann, Hanna; Bender, Benjamin; Sollmann, Nico; Havla, Joachim ORCID: https://orcid.org/0000-0002-4386-1340; Hemmer, Bernhard; Berlis, Ansgar; Wiestler, Benedikt; Kümpfel, Tania; Seelos, Klaus; Dünschede, Jutta; Kemmner, Roswitha; Beer, Meinrad; Dietrich, Jennifer und Schaller, Jonas
(2024):
Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing–remitting multiple sclerosis, the ProVal-MS study.
In: Neurological Research and Practice, Bd. 6, 15
[PDF, 1MB]
Benussi, Alberto; Premi, Enrico; Grassi, Mario; Alberici, Antonella; Cantoni, Valentina; Gazzina, Stefano; Archetti, Silvana; Gasparotti, Roberto; Fumagalli, Giorgio G.; Bouzigues, Arabella; Russell, Lucy L.; Samra, Kiran; Cash, David M.; Bocchetta, Martina; Todd, Emily G.; Convery, Rhian S.; Swift, Imogen; Sogorb-Esteve, Aitana; Heller, Carolin; van Swieten, John C.; Jiskoot, Lize C.; Seelaar, Harro; Sanchez-Valle, Raquel; Moreno, Fermin; Laforce, Jr Robert; Graff, Caroline; Synofzik, Matthis; Galimberti, Daniela; Rowe, James B.; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; Mendonca, Alexandre; Tiraboschi, Pietro; Butler, Chris R.; Santana, Isabel; Gerhard, Alexander; Le Ber, Isabelle; Pasquier, Florence; Ducharme, Simon; Levin, Johannes; Sorbi, Sandro; Otto, Markus; Padovani, Alessandro; Rohrer, Jonathan D. und Borroni, Barbara
(2024):
Diagnostic accuracy of research criteria for prodromal frontotemporal dementia.
In: Alzheimers Research & Therapy, Bd. 16, Nr. 1, 10
[PDF, 1MB]
Berron, David; Glanz, Wenzel; Clark, Lindsay; Basche, Kristin; Grande, Xenia; Guesten, Jeremie; Billette, Ornella V.; Hempen, Ina; Naveed, Muhammad Hashim; Diersch, Nadine; Butryn, Michaela; Spottke, Annika; Buerger, Katharina; Perneczky, Robert; Schneider, Anja; Teipel, Stefan; Wiltfang, Jens; Johnson, Sterling; Wagner, Michael; Jessen, Frank und Duezel, Emrah
(2024):
A remote digital memory composite to detect cognitive impairment in memory clinic samples in unsupervised settings using mobile devices.
In: Npj Digital Medicine, Bd. 7, Nr. 1, 79
[PDF, 2MB]
Biechele, Gloria; Rauchmann, Boris-Stephan; Janowitz, Daniel; Buerger, Katharina; Franzmeier, Nicolai; Weidinger, Endy; Guersel, Selim; Schuster, Sebastian; Finze, Anika; Harris, Stefanie; Lindner, Simon; Albert, Nathalie L.; Wetzel, Christian; Rupprecht, Rainer; Rominger, Axel; Palleis, Carla; Katzdobler, Sabrina; Burow, Lena; Kurz, Carolin; Zaganjori, Mirlind; Trappmann, Lena-Katharina; Goldhardt, Oliver; Grimmer, Timo; Haeckert, Jan; Keeser, Daniel; Stoecklein, Sophia; Morenas-Rodriguez, Estrella; Bartenstein, Peter; Levin, Johannes; Hoeglinger, Guenter U.; Simons, Mikael; Perneczky, Robert und Brendel, Matthias
(2024):
Associations between sex, body mass index and the individual microglial response in Alzheimer's disease.
In: Journal of Neuroinflammation, Bd. 21, Nr. 1, 30
[PDF, 2MB]
Bischof, Gérard N.; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843; Barthel, Henryk; Theis, Hendrik; Barbe, Michael; Bartenstein, Peter; Claasen, Joseph; Danek, Adrian ORCID: https://orcid.org/0000-0001-8857-5383; Höglinger, Günter; Levin, Johannes; Marek, Ken; Neumaier, Bernd; Palleis, Carla; Patt, Marianne; Rullmann, Michael; Saur, Dorothee; Schroeter, Matthias L.; Seibyl, John; Song, Mengmeng; Stephens, Andrew; Sabri, Osama; Drzezga, Alexander und Eimeren, Thilo van
(2024):
Improved Tau PET SUVR Quantification in 4-Repeat Tau Phenotypes with [18F]PI-2620.
In: Journal of Nuclear Medicine, Bd. 65, Nr. 6: S. 952-955
[PDF, 824kB]
Blickhaeuser, Beryll; Stenton, Sarah L.; Neuhofer, Christiane M.; Floride, Elisa; Nesbitt, Victoria; Fratter, Carl; Koch, Johannes; Kauffmann, Birgit; Catarino, Claudia; Schlieben, Lea Dewi; Kopajtich, Robert; Carelli, Valerio; Sadun, Alfredo A.; McFarland, Robert; Fang, Fang; La Morgia, Chiara; Paquay, Stephanie; Nassogne, Marie Cecile; Ghezzi, Daniele; Lamperti, Costanza; Wortmann, Saskia; Poulton, Jo; Klopstock, Thomas und Prokisch, Holger
(2024):
Digenic Leigh syndrome on the background of the m.11778G>A Leber hereditary optic neuropathy variant.
In: Brain
[PDF, 555kB]
Blömeke, Lara; Rehn, Fabian; Kraemer‐Schulien, Victoria; Kutzsche, Janine; Pils, Marlene; Bujnicki, Tuyen; Lewczuk, Piotr; Kornhuber, Johannes; Freiesleben, Silka D.; Schneider, Luisa‐Sophie; Preis, Lukas; Priller, Josef; Spruth, Eike J.; Altenstein, Slawek; Lohse, Andrea; Schneider, Anja; Fliessbach, Klaus; Wiltfang, Jens; Hansen, Niels; Rostamzadeh, Ayda; Düzel, Emrah; Glanz, Wenzel; Incesoy, Enise I.; Butryn, Michaela; Buerger, Katharina; Janowitz, Daniel; Ewers, Michael; Perneczky, Robert; Rauchmann, Boris‐Stephan; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Laske, Christoph; Munk, Matthias H.; Sanzenbacher, Carolin; Spottke, Annika; Roy‐Kluth, Nina; Heneka, Michael T.; Brosseron, Frederic; Wagner, Michael; Wolfsgruber, Steffen; Kleineidam, Luca; Stark, Melina; Schmid, Matthias; Jessen, Frank; Bannach, Oliver; Willbold, Dieter und Peters, Oliver
(2024):
Aβ oligomers peak in early stages of Alzheimer's disease preceding tau pathology.
In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Bd. 16, Nr. 2, e12589
[PDF, 1MB]
Brenner, David ORCID: https://orcid.org/0000-0002-1535-3146; Sieverding, Kirsten ORCID: https://orcid.org/0009-0006-7223-5943; Srinidhi, Jahnavi ORCID: https://orcid.org/0009-0003-8416-2276; Zellner, Susanne ORCID: https://orcid.org/0000-0002-8523-824X; Secker, Christopher ORCID: https://orcid.org/0000-0002-7222-536X; Yilmaz, Rüstem ORCID: https://orcid.org/0000-0002-4261-5236; Dyckow, Julia ORCID: https://orcid.org/0000-0003-1423-9322; Amr, Shady ORCID: https://orcid.org/0009-0000-1597-1510; Ponomarenko, Anna ORCID: https://orcid.org/0009-0009-9223-9310; Tunaboylu, Esra ORCID: https://orcid.org/0009-0002-4266-4449; Douahem, Yasmin ORCID: https://orcid.org/0009-0004-7079-7120; Schlag, Joana S. ORCID: https://orcid.org/0009-0005-2001-4121; Rodríguez Martínez, Lucía ORCID: https://orcid.org/0009-0003-3576-3702; Kislinger, Georg ORCID: https://orcid.org/0000-0002-6559-7421; Niemann, Cornelia ORCID: https://orcid.org/0009-0000-7197-6770; Nalbach, Karsten ORCID: https://orcid.org/0000-0002-3928-4026; Ruf, Wolfgang P. ORCID: https://orcid.org/0000-0002-8105-6123; Uhl, Jonathan ORCID: https://orcid.org/0009-0005-1754-173X; Hollenbeck, Johanna ORCID: https://orcid.org/0009-0009-9877-7822; Schirmer, Lucas ORCID: https://orcid.org/0000-0001-7142-4116; Catanese, Alberto ORCID: https://orcid.org/0000-0002-8266-4913; Lobsiger, Christian S. ORCID: https://orcid.org/0000-0002-4313-010X; Danzer, Karin M. ORCID: https://orcid.org/0000-0003-0133-7046; Yilmazer-Hanke, Deniz ORCID: https://orcid.org/0000-0003-1483-0286; Münch, Christian ORCID: https://orcid.org/0000-0003-3832-090X; Koch, Philipp ORCID: https://orcid.org/0000-0003-3713-8786; Freischmidt, Axel ORCID: https://orcid.org/0000-0003-1216-3790; Fetting, Martina ORCID: https://orcid.org/0000-0002-0500-8218; Behrends, Christian ORCID: https://orcid.org/0000-0002-9184-7607; Parlato, Rosanna ORCID: https://orcid.org/0000-0001-6682-9645 und Weishaupt, Jochen H. ORCID: https://orcid.org/0000-0002-3399-9784
(2024):
A TBK1 variant causes autophagolysosomal and motoneuron pathology without neuroinflammation in mice.
In: Journal of Experimental Medicine, Bd. 221, Nr. 5, e20221190
[PDF, 7MB]
Brink, Hilde van den ORCID: https://orcid.org/0000-0003-3094-0274; Pham, Stanley; Siero, Jeroen C.; Arts, Tine; Onkenhout, Laurien; Kuijf, Hugo ORCID: https://orcid.org/0000-0001-6997-9059; Hendrikse, Jeroen ORCID: https://orcid.org/0000-0001-6384-6140; Wardlaw, Joanna M. ORCID: https://orcid.org/0000-0002-9812-6642; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Zwanenburg, Jaco J. und Biessels, Geert Jan ORCID: https://orcid.org/0000-0001-6862-2496
(2024):
Assessment of Small Vessel Function Using 7T MRI in Patients With Sporadic Cerebral Small Vessel Disease.
In: Neurology, Bd. 102, Nr. 5
[PDF, 564kB]
Brugger, Melanie; Lauri, Antonella; Zhen, Yan; Gramegna, Laura L.; Zott, Benedikt; Sekulic, Nikolina; Fasano, Giulia; Kopajtich, Robert; Cordeddu, Viviana; Radio, Francesca Clementina; Mancini, Cecilia; Pizzi, Simone; Paradisi, Graziamaria; Zanni, Ginevra; Vasco, Gessica; Carrozzo, Rosalba; Palombo, Flavia; Tonon, Caterina; Lodi, Raffaele; Morgia, Chiara La; Arelin, Maria; Blechschmidt, Cristiane; Finck, Tom; Sorensen, Vigdis; Kreiser, Kornelia; Strobl-Wildemann, Gertrud; Daum, Hagit; Michaelson-Cohen, Rachel; Ziccardi, Lucia; Zampino, Giuseppe; Prokisch, Holger; Jamra, Rami Abou; Fiorini, Claudio; Arzberger, Thomas; Winkelmann, Juliane; Caporali, Leonardo; Carelli, Valerio; Stenmark, Harald; Tartaglia, Marco und Wagner, Matias
(2024):
Bi-allelic variants in SNF8 cause a disease spectrum ranging from severe developmental and epileptic encephalopathy to syndromic optic atrophy.
In: American Journal of Human Genetics, Bd. 111, Nr. 3
[PDF, 7MB]
Calligaris, Matteo; Spano, Donatella P.; Bonelli, Simone; Mueller, Stephan A.; Carcione, Claudia; D'apolito, Danilo; Amico, Giandomenico; Miele, Monica; Di Bella, Mariangela; Zito, Giovanni; Nuti, Elisa; Rossello, Armando; Blobel, Carl P.; Lichtenthaler, Stefan F. und Scilabra, Simone D.
(2024):
iRhom2 regulates ectodomain shedding and surface expression of the major histocompatibility complex (MHC) class I.
In: Cellular and Molecular Life Sciences, Bd. 81, Nr. 1, 163
[PDF, 5MB]
Carmona, Asuncion; Carboni, Eleonora; Gomes, Lucas Caldi; Roudeau, Stephane; Maass, Fabian; Lenz, Christof; Ortega, Richard und Lingor, Paul
(2024):
Metal dyshomeostasis in the substantia nigra of patients with Parkinson's disease or multiple sclerosis.
In: Journal of Neurochemistry, Bd. 168, Nr. 2: S. 128-141
[PDF, 7MB]
Chang, Yinshui; Bach, Luisa; Hasiuk, Marko; Wen, Lifen; Elmzzahi, Tarek; Tsui, Carlson; Gutierrez-Melo, Nicolas; Steffen, Teresa; Utzschneider, Daniel T.; Raj, Timsse; Jost, Paul Jonas; Heink, Sylvia; Cheng, Jingyuan; Burton, Oliver T.; Zeitraeg, Julia; Alterauge, Dominik; Dahlstroem, Frank; Becker, Jennifer-Christin; Kastl, Melanie; Symeonidis, Konstantinos; van Uelft, Martina; Becker, Matthias; Reschke, Sarah; Krebs, Stefan; Blum, Helmut; Abdullah, Zeinab; Paeschke, Katrin; Ohnmacht, Caspar; Neumann, Christian; Liston, Adrian; Meissner, Felix; Korn, Thomas; Hasenauer, Jan; Heissmeyer, Vigo; Beyer, Marc; Kallies, Axel; Jeker, Lukas T. und Baumjohann, Dirk
(2024):
TGF-β specifies TFH versus TH17 cell fates in murine CD4+ T cells through c-Maf.
In: Science Immunology, Bd. 9, Nr. 93, eadd4818
Crespo-Avilan, Gustavo E.; Hernandez-Resendiz, Sauri; Ramachandra, Chrishan J.; Ungureanu, Victor; Lin, Ying-Hsi; Lu, Shengjie; Bernhagen, Jurgen; El Bounkari, Omar; Preissner, Klaus T.; Liehn, Elisa A. und Hausenloy, Derek J.
(2024):
Metabolic reprogramming of immune cells by mitochondrial division inhibitor-1 to prevent post-vascular injury neointimal hyperplasia.
In: Atherosclerosis, Bd. 390, 117450
[PDF, 13MB]
Deike, Katerina; Decker, Andreas; Scheyhing, Paul; Harten, Julia; Zimmermann, Nadine; Paech, Daniel; Peters, Oliver; Freiesleben, Silka D.; Schneider, Luisa-Sophie; Preis, Lukas; Priller, Josef; Spruth, Eike; Altenstein, Slawek; Lohse, Andrea; Fliessbach, Klaus; Kimmich, Okka; Wiltfang, Jens; Bartels, Claudia; Hansen, Niels; Jessen, Frank; Rostamzadeh, Ayda; Düzel, Emrah; Glanz, Wenzel; Incesoy, Enise I.; Butryn, Michaela; Buerger, Katharina; Janowitz, Daniel; Ewers, Michael; Perneczky, Robert; Rauchmann, Boris-Stephan; Teipel, Stefan; Kilimann, Ingo; Goerss, Doreen; Laske, Christoph; Munk, Matthias H.; Spottke, Annika; Roy, Nina; Wagner, Michael; Roeske, Sandra; Heneka, Michael T.; Brosseron, Frederic; Ramirez, Alfredo; Dobisch, Laura; Wolfsgruber, Steffen; Kleineidam, Luca; Yakupov, Renat; Stark, Melina; Schmid, Matthias C.; Berger, Moritz; Hetzer, Stefan; Dechent, Peter; Scheffler, Klaus; Petzold, Gabor C.; Schneider, Anja; Effland, Alexander und Radbruch, Alexander
(2024):
Machine Learning–Based Perivascular Space Volumetry in Alzheimer Disease.
In: Investigative Radiology [Forthcoming]
Diddens, Jolien ORCID: https://orcid.org/0000-0002-8720-7420; Lepennetier, Gildas; Friedrich, Verena; Schmidt, Monika; Brand, Rosa M. ORCID: https://orcid.org/0009-0000-0737-8362; Georgieva, Tanya; Hemmer, Bernhard ORCID: https://orcid.org/0000-0001-5985-6784 und Lehmann-Horn, Klaus ORCID: https://orcid.org/0000-0001-5488-7549
(2024):
Single-Cell Profiling Indicates a Proinflammatory Role of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis.
In: Neurology Neuroimmunology & Neuroinflammation, Bd. 11, Nr. 1, e200185
Doering, Yvonne; van der Vorst, Emiel P. C.; Yan, Yi; Neideck, Carlos; Blanchet, Xavier; Jansen, Yvonne; Kemmerich, Manuela; Bayasgalan, Soyolmaa; Peters, Linsey J. F.; Hristov, Michael; Bidzhekov, Kiril; Yin, Changjun; Zhang, Xi; Leberzammer, Julian; Li, Ya; Park, Inhye; Kral, Maria; Nitz, Katrin; Parma, Laura; Gencer, Selin; Habenicht, Andreas J. R.; Faussner, Alexander; Teupser, Daniel; Monaco, Claudia; Holdt, Lesca; Megens, Remco T. A.; Atzler, Dorothee; Santovito, Donato; von Hundelshausen, Philipp und Weber, Christian
(2024):
Identification of a non-canonical chemokine-receptor pathway suppressing regulatory T cells to drive atherosclerosis.
In: Nature Cardiovascular Research, Bd. 3, Nr. 2
[PDF, 21MB]
Dvoretskova, Elena; Ho, May C.; Kittke, Volker; Neuhaus, Florian; Vitali, Ilaria; Lam, Daniel D.; Delgado, Irene; Feng, Chao; Torres, Miguel; Winkelmann, Juliane und Mayer, Christian
(2024):
Spatial enhancer activation influences inhibitory neuron identity during mouse embryonic development.
In: Nature Neuroscience, Bd. 27, Nr. 5
[PDF, 13MB]
Dörner, Marc ORCID: https://orcid.org/0000-0003-3229-1677; Seebach, Katharina; Heneka, Michael T.; Menze, Inga; Känel, Roland von ORCID: https://orcid.org/0000-0002-8929-5129; Euler, Sebastian; Schreiber, Frank ORCID: https://orcid.org/0000-0002-9484-8613; Arndt, Philipp; Neumann, Katja; Hildebrand, Annkatrin; John, Anna-Charlotte; Tyndall, Anthony; Kirchebner, Johannes; Tacik, Pawel; Jansen, Robin; Grimm, Alexander; Henneicke, Solveig ORCID: https://orcid.org/0000-0002-9103-7276; Perosa, Valentina ORCID: https://orcid.org/0000-0002-3551-5237; Meuth, Sven G. ORCID: https://orcid.org/0000-0003-2571-3501; Peters, Oliver; Hellmann-Regen, Julian; Preis, Lukas; Priller, Josef; Spruth, Eike Jakob; Schneider, Anja; Fliessbach, Klaus; Wiltfang, Jens; Jessen, Frank; Rostamzadeh, Ayda; Glanz, Wenzel ORCID: https://orcid.org/0000-0002-5865-4176; Schulze, Jan Ben; Schiebler, Sarah Lavinia Florence ORCID: https://orcid.org/0009-0000-8112-546X; Buerger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris-Stephan ORCID: https://orcid.org/0000-0003-4547-6240; Teipel, Stefan; Kilimann, Ingo; Laske, Christoph; Munk, Matthias H.; Spottke, Annika; Roy-Kluth, Nina; Wagner, Michael ORCID: https://orcid.org/0000-0003-2589-6440; Frommann, Ingo ORCID: https://orcid.org/0000-0002-7244-2014; Lüsebrink, Falk; Dechent, Peter; Hetzer, Stefan; Scheffler, Klaus; Kleineidam, Luca; Stark, Melina; Schmid, Matthias; Ersözlü, Ersin ORCID: https://orcid.org/0000-0001-6503-5894; Brosseron, Frederic; Ewers, Michael; Schott, Björn H. ORCID: https://orcid.org/0000-0002-8237-4481; Düzel, Emrah; Ziegler, Gabriel; Mattern, Hendrik; Schreiber, Stefanie ORCID: https://orcid.org/0000-0003-4439-4374 und Bernal, Jose ORCID: https://orcid.org/0000-0003-3167-5134
(2024):
Inferior Frontal Sulcal Hyperintensities on Brain MRI Are Associated with Amyloid Positivity beyond Age—Results from the Multicentre Observational DELCODE Study.
In: Diagnostics, Bd. 14, Nr. 9, 940
[PDF, 573kB]
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Evaluation of a multimodal diagnostic algorithm for prediction of cognitive impairment in elderly patients with dizziness.
In: Journal of Neurology [Forthcoming]
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Tau accumulation is associated with dopamine deficiency in vivo in four-repeat tauopathies.
In: European Journal of Nuclear Medicine and Molecular Imaging, Bd. 51, Nr. 5: S. 1268-1286
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A GGC-repeat expansion in ZFHX3 encoding polyglycine causes spinocerebellar ataxia type 4 and impairs autophagy.
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Elevated CSF GAP-43 is associated with accelerated tau accumulation and spread in Alzheimer's disease.
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Structural and functional organization of visual responses in the inferior olive of larval zebrafish.
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Lysosomal damage sensing and lysophagy initiation by SPG20-ITCH.
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Cellular depletion of major cathepsin proteases reveals their concerted activities for lysosomal proteolysis.
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L-Lactate Treatment at 24 h and 48 h after Acute Experimental Stroke Is Neuroprotective via Activation of the L-Lactate Receptor HCA1.
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A brain-enriched circular RNA controls excitatory neurotransmission and restricts sensitivity to aversive stimuli.
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The Traumatic Inoculation Process Affects TSPO Radioligand Uptake in Experimental Orthotopic Glioblastoma.
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Recommendations for optimal interdisciplinary management and healthcare settings for patients with rare neurological diseases.
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Global, neuronal or β cell-specific deletion of inceptor improves glucose homeostasis in male mice with diet-induced obesity.
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The comorbidity and co-medication profile of patients with progressive supranuclear palsy.
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Multiple sclerosis endophenotypes identified by high-dimensional blood signatures are associated with distinct disease trajectories.
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Phenotypic and genome-wide studies on dicarbonyls: major associations to glomerular filtration rate and gamma-glutamyltransferase activity.
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Engrailed 1 deficiency induces changes in ciliogenesis during human neuronal differentiation.
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Characterization of Vasogenic and Cytotoxic Brain Edema Formation After Experimental Traumatic Brain Injury by Free Water Diffusion Magnetic Resonance Imaging.
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Single cell transcriptomics of cerebrospinal fluid cells from patients with recent-onset narcolepsy.
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A biological classification of Parkinson's disease: the SynNeurGe research diagnostic criteria.
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CCR3-dependent eosinophil recruitment is regulated by sialyltransferase ST3Gal-IV.
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Dystonia in ATP Synthase Defects: Reconnecting Mitochondria and Dopamine.
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Genome Aggregation Database Version 4-New Challenges of Variant Analysis in Movement Disorders.
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Dystonia and mitochondrial disease: the movement disorder connection revisited in 900 genetically diagnosed patients.
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Genome Sequencing for Cases Unsolved by Exome Sequencing: Identifying a Single-Exon Deletion in TBCK in a Case from 30 Years Ago.
In: Neuropediatrics
Joseph-Mathurin, Nelly; Feldman, Rebecca L.; Lu, Ruijin; Shirzadi, Zahra; Toomer, Carmen; Clair, Junie R. Saint; Ma, Yinjiao; Mckay, Nicole S.; Strain, Jeremy F.; Kilgore, Collin; Friedrichsen, Karl A.; Chen, Charles D.; Gordon, Brian A.; Chen, Gengsheng; Hornbeck, Russ C.; Massoumzadeh, Parinaz; Mccullough, Austin A.; Wang, Qing; Li, Yan; Wang, Guoqiao; Keefe, Sarah J.; Schultz, Stephanie A.; Cruchaga, Carlos; Preboske, Gregory M.; Jack, Clifford R.; Llibre-Guerra, Jorge J.; Allegri, Ricardo F.; Ances, Beau M.; Berman, Sarah B.; Brooks, William S.; Cash, David M.; Day, Gregory S.; Fox, Nick C.; Fulham, Michael; Ghetti, Bernardino; Johnson, Keith A.; Jucker, Mathias; Klunk, William E.; la Fougere, Christian; Levin, Johannes; Niimi, Yoshiki; Oh, Hwamee; Perrin, Richard J.; Reischl, Gerald; Ringman, John M.; Saykin, Andrew J.; Schofield, Peter R.; Su, Yi; Supnet-Bell, Charlene; Voeglein, Jonathan; Yakushev, Igor; Brickman, Adam M.; Morris, John C.; Mcdade, Eric; Xiong, Chengjie; Bateman, Randall J.; Chhatwal, Jasmeer P. und Benzinger, Tammie L. S.
(2024):
Presenilin-1 mutation position influences amyloidosis, small vessel disease, and dementia with disease stage.
In: Alzheimers & Dementia
[PDF, 6MB]
Kaiser, Lena; Quach, S.; Zounek, A. J.; Wiestler, B.; Zatcepin, A.; Holzgreve, A.; Bollenbacher, A.; Bartos, L. M.; Ruf, V. C.; Boening, G.; Thon, N.; Herms, J.; Riemenschneider, M. J.; Stoecklein, S.; Brendel, M.; Rupprecht, R.; Tonn, J. C.; Bartenstein, P.; von Baumgarten, L.; Ziegler, S. und Albert, N. L.
(2024):
Enhancing predictability of IDH mutation status in glioma patients at initial diagnosis: a comparative analysis of radiomics from MRI, [18F]FET PET, and TSPO PET.
In: European Journal of Nuclear Medicine and Molecular Imaging
[PDF, 1MB]
Kaltenecker, Doris; Al-Maskari, Rami; Negwer, Moritz; Hoeher, Luciano; Kofler, Florian; Zhao, Shan; Todorov, Mihail ORCID: https://orcid.org/0000-0002-8627-1260; Rong, Zhouyi; Paetzold, Johannes Christian; Wiestler, Benedikt ORCID: https://orcid.org/0000-0002-2963-7772; Piraud, Marie ORCID: https://orcid.org/0000-0002-4917-2458; Rueckert, Daniel ORCID: https://orcid.org/0000-0002-5683-5889; Geppert, Julia; Morigny, Pauline; Rohm, Maria ORCID: https://orcid.org/0000-0003-3926-1534; Menze, Bjoern H.; Herzig, Stephan ORCID: https://orcid.org/0000-0003-3950-3652; Berriel Diaz, Mauricio ORCID: https://orcid.org/0000-0003-4670-919X und Ertürk, Ali ORCID: https://orcid.org/0000-0001-5163-5100
(2024):
Virtual reality-empowered deep-learning analysis of brain cells.
In: Nature Methods [Forthcoming]
[PDF, 7MB]
Koupourtidou, Christina ORCID: https://orcid.org/0000-0002-8352-1498; Schwarz, Veronika; Aliee, Hananeh; Frerich, Simon ORCID: https://orcid.org/0000-0002-8275-6113; Fischer-Sternjak, Judith; Bocchi, Riccardo ORCID: https://orcid.org/0000-0002-4105-6807; Simon-Ebert, Tatiana; Bai, Xianshu ORCID: https://orcid.org/0000-0002-4758-1645; Sirko, Swetlana ORCID: https://orcid.org/0000-0001-5950-616X; Kirchhoff, Frank ORCID: https://orcid.org/0000-0002-2324-2761; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Götz, Magdalena ORCID: https://orcid.org/0000-0003-1551-9203; Theis, Fabian J. ORCID: https://orcid.org/0000-0002-2419-1943 und Ninkovic, Jovica ORCID: https://orcid.org/0000-0002-4381-0041
(2024):
Shared inflammatory glial cell signature after stab wound injury, revealed by spatial, temporal, and cell-type-specific profiling of the murine cerebral cortex.
In: Nature Communications, Bd. 15, Nr. 1, 2866
[PDF, 57MB]
Larsen, Frode Kibsgaard; Baksh, R. Asaad; Mcglinchey, Eimear; Langballe, Ellen Melbye; Benejam, Bessy; Beresford-Webb, Jessica; Mccarron, Mary; Coppus, Antonia; Falquero, Segolene; Fortea, Juan; Levin, Johannes; Loosli, Sandra V.; Mark, Ruth; Rebillat, Anne-Sophie; Zaman, Shahid und Strydom, Andre
(2024):
Age of Alzheimer's disease diagnosis in people with Down syndrome and associated factors: Results from the Horizon 21 European Down syndrome consortium.
In: Alzheimers & Dementia, Bd. 20, Nr. 5: S. 3270-3280
[PDF, 255kB]
Lauerer, Markus; McGinnis, Julian; Bussas, Matthias; El Husseini, Malek; Pongratz, Viola; Engl, Christina; Wuschek, Alexander; Berthele, Achim; Riederer, Isabelle; Kirschke, Jan S.; Zimmer, Claus; Hemmer, Bernhard und Muehlau, Mark
(2024):
Prognostic value of spinal cord lesion measures in early relapsing-remitting multiple sclerosis.
In: Journal of Neurology Neurosurgery and Psychiatry, Bd. 95, Nr. 1: S. 37-43
[PDF, 1MB]
Leu, Chia-Luen; Lam, Daniel D.; Salminen, Aaro; Wefers, Benedikt; Becker, Lore; Garrett, Lillian; Rozman, Jan; Wurst, Wolfgang; de Angelis, Martin Hrabe; Hoelter, Sabine M.; Winkelmann, Juliane und Williams, Rhiannan H.
(2024):
A patient-enriched MEIS1 coding variant causes a restless legs syndrome-like phenotype in mice.
In: Sleep, Bd. 47, Nr. 5
Levin, Johannes ORCID: https://orcid.org/0000-0001-5092-4306; Baiardi, Simone; Quadalti, Corinne; Rossi, Marcello; Mammana, Angela; Vöglein, Jonathan; Bernhardt, Alexander; Perrin, Richard J.; Jucker, Mathias; Preische, Oliver; Hofmann, Anna; Höglinger, Günter U.; Cairns, Nigel J.; Franklin, Erin E.; Chrem, Patricio; Cruchaga, Carlos; Berman, Sarah B.; Chhatwal, Jasmeer P.; Daniels, Alisha; Day, Gregory S.; Ryan, Natalie S.; Goate, Alison M.; Gordon, Brian A.; Huey, Edward D.; Ibanez, Laura; Karch, Celeste M.; Lee, Jae‐Hong; Llibre‐Guerra, Jorge; Lopera, Francisco; Masters, Colin L.; Morris, John C.; Noble, James M.; Renton, Alan E.; Roh, Jee Hoon; Frosch, Matthew P.; Keene, C. Dirk; McLean, Catriona; Sanchez‐Valle, Raquel; Schofield, Peter R.; Supnet‐Bell, Charlene; Xiong, Chengjie; Giese, Armin; Hansson, Oskar; Bateman, Randall J.; McDade, Eric und Parchi, Piero ORCID: https://orcid.org/0000-0002-9444-9524
(2024):
α‐Synuclein seed amplification assay detects Lewy body co‐pathology in autosomal dominant Alzheimer's disease late in the disease course and dependent on Lewy pathology burden.
In: Alzheimer's & Dementia [Forthcoming]
[PDF, 1MB]
Liebscher, Maxie ORCID: https://orcid.org/0009-0000-7625-5673; Dell’Orco, Andrea ORCID: https://orcid.org/0000-0002-3964-8360; Doll-Lee, Johanna; Buerger, Katharina; Dechent, Peter; Ewers, Michael; Fliessbach, Klaus; Glanz, Wenzel; Hetzer, Stefan; Janowitz, Daniel; Kilimann, Ingo; Laske, Christoph; Lüsebrink, Falk; Munk, Matthias; Perneczky, Robert; Peters, Oliver; Preis, Lukas ORCID: https://orcid.org/0000-0001-7601-6410; Priller, Josef; Rauchmann, Boris; Rostamzadeh, Ayda; Roy-Kluth, Nina; Scheffler, Klaus; Schneider, Anja; Schott, Björn H. ORCID: https://orcid.org/0000-0002-8237-4481; Spottke, Annika; Spruth, Eike; Teipel, Stefan; Wiltfang, Jens; Jessen, Frank; Düzel, Emrah; Wagner, Michael; Röske, Sandra und Wirth, Miranka
(2024):
Short communication: Lifetime musical activity and resting-state functional connectivity in cognitive networks.
In: PLOS ONE
19(5), e0299939
[PDF, 1MB]
Linnerbauer, Mathias; Loesslein, Lena; Vandrey, Oliver; Peter, Anne; Han, Yanan; Tsaktanis, Thanos; Wogram, Emile; Needhamsen, Maria; Kular, Lara; Nagel, Lisa; Zissler, Julia; Andert, Marie; Meszaros, Lisa; Hanspach, Jannis; Zuber, Finnja; Naumann, Ulrike J.; Diebold, Martin; Wheeler, Michael A.; Beyer, Tobias; Nirschl, Lucy; Cirac, Ana; Laun, Frederik B.; Guenther, Claudia; Winkler, Jurgen; Baeuerle, Tobias; Jagodic, Maja; Hemmer, Bernhard; Prinz, Marco; Quintana, Francisco J. und Rothhammer, Veit
(2024):
The astrocyte-produced growth factor HB-EGF limits autoimmune CNS pathology.
In: Nature Immunology
[PDF, 23MB]
Liubchenko, Grigory; Boening, Guido; Zacherl, Mathias; Rumiantcev, Mikhail; Unterrainer, Lena M.; Gildehaus, Franz Josef; Brendel, Matthias; Resch, Sandra; Bartenstein, Peter; Ziegler, Sibylle I. und Delker, Astrid
(2024):
Image-based dosimetry for [225Ac]Ac-PSMA-I&T therapy and the effect of daughter-specific pharmacokinetics.
In: European Journal of Nuclear Medicine and Molecular Imaging
[PDF, 1MB]
Luib, Elena; Demleitner, Antonia F.; Cordts, Isabell; Westenberg, Erica; Rau, Petra; Puerner, Dominik; Haller, Bernhard und Lingor, Paul
(2024):
Reduced tear fluid production in neurological diseases: a cohort study in 708 patients.
In: Journal of Neurology, Bd. 271, Nr. 4: S. 1837-1843
[PDF, 1MB]
Mai, Hongcheng; Luo, Jie; Hoeher, Luciano; Al-Maskari, Rami; Horvath, Izabela; Chen, Ying; Kofler, Florian; Piraud, Marie; Paetzold, Johannes C. C.; Modamio, Jennifer; Todorov, Mihail; Elsner, Markus; Hellal, Farida und Ertuerk, Ali
(2024):
Whole-body cellular mapping in mouse using standard IgG antibodies.
In: Nature Biotechnology, Bd. 42, Nr. 4
[PDF, 14MB]
Mancuso, Michelangelo; Lopriore, Piervito; Lamperti, Costanza; Klopstock, Thomas; Rahman, Shamima; Licchetta, Laura; Kornblum, Cornelia; Wortmann, Saskia B.; Dollfus, Helene; Papadopoulou, Maria T.; Arzimanoglou, Alexis; Scarpa, Maurizio; Graessner, Holm und Evangelista, Teresinha
(2024):
Current management of primary mitochondrial disorders in EU countries: the European Reference Networks survey.
In: Journal of Neurology, Bd. 271, Nr. 2: S. 835-840
[PDF, 2MB]
Mancuso, Michelangelo; Papadopoulou, Maria T.; Ng, Yi Shiau; Ardissone, Anna; Bellusci, Marcello; Bertini, Enrico; Di Vito, Lidia; Evangelista, Teresinha; Fons, Carmen; Hikmat, Omar; Horvath, Rita; Klopstock, Thomas; Kornblum, Cornelia; Lamperti, Costanza; Licchetta, Laura; Molnar, Maria Judit; Varhaug, Kristin N.; O'Callaghan, Mar; Pressler, Ronit M.; Schiff, Manuel; Servidei, Serenella; Szabo, Nora; Gorman, Grainne S.; Cross, J. Helen und Rahman, Shamima
(2024):
Management of seizures in patients with primary mitochondrial diseases: consensus statement from the InterERNs Mitochondrial Working Group.
In: European Journal of Neurology
[PDF, 3MB]
Mauker, Philipp; Beckmann, Daniela; Kitowski, Annabel; Heise, Constanze; Wientjens, Chantal; Davidson, Andrew J.; Wanderoy, Simone; Fabre, Gabin; Harbauer, Angelika B.; Wood, Will; Wilhelm, Christoph; Thorn-Seshold, Julia; Misgeld, Thomas; Kerschensteiner, Martin und Thorn-Seshold, Oliver
(2024):
Fluorogenic Chemical Probes for Wash-free Imaging of Cell Membrane Damage in Ferroptosis, Necrosis, and Axon Injury.
In: Journal of the American Chemical Society
Meindl, Maria; Zatcepin, Artem; Gnörich, Johannes; Scheifele, Maximilian; Zaganjori, Mirlind; Groß, Mattes; Lindner, Simon; Schaefer, Rebecca; Simmet, Marcel; Roemer, Sebastian; Katzdobler, Sabrina; Levin, Johannes; Höglinger, Günter; Bischof, Ann-Cathrin; Barthel, Henryk; Sabri, Osama; Bartenstein, Peter; Saller, Thomas; Franzmeier, Nicolai ORCID: https://orcid.org/0000-0001-9736-2283; Ziegler, Sibylle und Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843
(2024):
Assessment of [18F]PI-2620 Tau-PET Quantification via Non-Invasive Automatized Image Derived Input Function.
In: European Journal of Nuclear Medicine and Molecular Imaging [Forthcoming]
[PDF, 6MB]
Merino-Serrais, Paula; Plaza-Alonso, Sergio; Hellal, Farida; Valero-Freitag, Susana; Kastanauskaite, Asta; Plesnila, Nikolaus und DeFelipe, Javier
(2024):
Structural changes of CA1 pyramidal neurons after stroke in the contralesional hippocampus.
In: Brain Pathology, Bd. 34, Nr. 3
[PDF, 4MB]
Mortazavi, Matin ORCID: https://orcid.org/0000-0002-0826-7661; Gerdes, Lisa Ann; Hizarci, Öznur; Kümpfel, Tania ORCID: https://orcid.org/0000-0001-7509-5268; Anslinger, Katja; Padberg, Frank; Stöcklein, Sophia ORCID: https://orcid.org/0000-0003-0325-4674; Keeser, Daniel ORCID: https://orcid.org/0000-0002-0244-1024 und Ertl-Wagner, Birgit
(2024):
Impact of adult-onset multiple sclerosis on MRI-based intracranial volume: A study in clinically discordant monozygotic twins.
In: NeuroImage: Clinical, Bd. 42, 103597
[PDF, 6MB]
Nay, Sandra ORCID: https://orcid.org/0000-0002-4986-1181; Möhn, Nora ORCID: https://orcid.org/0000-0002-9102-124X; Grote-Levi, Lea; Bonifacius, Agnes; Saßmann, Mieke L.; Karacondi, Kevin; Tischer-Zimmermann, Sabine; Pöter, Henning; Mahmoudi, Nima; Wattjes, Mike P.; Maecker-Kolhoff, Britta; Höglinger, Günter; Eiz-Vesper, Britta und Skripuletz, Thomas
(2024):
Combined treatment with allogeneic Epstein–Barr- and human polyomavirus 1 specific T-cells in progressive multifocal leukoencephalopathy and EBV infection: a case report.
In: Therapeutic Advances in Neurological Disorders, Bd. 17
[PDF, 455kB]
Nuebling, G. ORCID: https://orcid.org/0000-0003-4492-7302; Wagemann, O.; Deb, S.; Wlasich, E.; Loosli, S. V.; Sandkühler, K.; Stockbauer, A.; Prix, C. und Levin, J.
(2024):
Validation of a German version of the dementia screening questionnaire for individuals with intellectual disabilities (DSQIID‐G) in Down's syndrome.
In: Journal of Intellectual Disability Research [Forthcoming]
[PDF, 358kB]
Palleis, Carla; Franzmeier, Nicolai; Weidinger, Endy; Bernhardt, Alexander M.; Katzdobler, Sabrina; Wall, Stephan; Ferschmann, Christian; Harris, Stefanie; Schmitt, Julia; Schuster, Sebastian; Gnoerich, Johannes; Finze, Anika; Biechele, Gloria; Lindner, Simon; Albert, Nathalie L.; Bartenstein, Peter; Sabri, Osama; Barthel, Henryk; Rupprecht, Rainer; Nuscher, Brigitte; Stephens, Andrew W.; Rauchmann, Boris-Stephan; Perneczky, Robert; Haass, Christian; Brendel, Matthias; Levin, Johannes und Hoeglinger, Guenter U.
(2024):
Association of Neurofilament Light Chain, [18F]PI-2620 Tau-PET, TSPO-PET, and Clinical Progression in Patients With β-Amyloid-Negative CBS.
In: Neurology, Bd. 102, Nr. 1, e207901
[PDF, 2MB]
Pasternak, Maurice ORCID: https://orcid.org/0000-0003-0647-172X; Mirza, Saira S.; Luciw, Nicholas; Mutsaerts, Henri J. M. M.; Petr, Jan; Thomas, David; Cash, David; Bocchetta, Martina; Tartaglia, Maria Carmela; Mitchell, Sara B.; Black, Sandra E.; Freedman, Morris; Tang‐Wai, David; Rogaeva, Ekaterina; Russell, Lucy L.; Bouzigues, Arabella; van Swieten, John C.; Jiskoot, Lize C.; Seelaar, Harro; Laforce, Robert; Tiraboschi, Pietro; Borroni, Barbara; Galimberti, Daniela; Rowe, James B.; Graff, Caroline; Finger, Elizabeth; Sorbi, Sandro; de Mendonça, Alexandre; Butler, Chris; Gerhard, Alex; Sanchez‐Valle, Raquel; Moreno, Fermin; Synofzik, Matthis; Vandenberghe, Rik; Ducharme, Simon; Levin, Johannes; Otto, Markus; Santana, Isabel; Strafella, Antonio P.; MacIntosh, Bradley J.; Rohrer, Jonathan D. und Masellis, Mario
(2024):
Longitudinal cerebral perfusion in presymptomatic genetic frontotemporal dementia: GENFI results.
In: Alzheimer's & Dementia, Bd. 20, Nr. 5: S. 3525-3542
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Perneczky, Robert ORCID: https://orcid.org/0000-0003-1981-7435; Hansen, Niels; Hofmann, Anna; Laske, Christoph; Priller, Josef; Grimmer, Timo; Frölich, Lutz; Düzel, Emrah; Jessen, Frank und Wiltfang, Jens
(2024):
Blood-Based Biomarkers for Early Alzheimer’s Disease Diagnosis in Real-World Settings.
In: Perneczky, Robert (Hrsg.):
Biomarkers for Alzheimer’s Disease Drug Development. Methods in Molecular Biology, Bd. 2785. New York: Humana, Springer Nature. S. 3-14
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(2024):
Penumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial.
In: International Journal of Stroke, Bd. 19, Nr. 1: S. 120-126
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(2024):
Ribosome inactivation regulates translation elongation in neurons.
In: Journal of Biological Chemistry, Bd. 300, Nr. 2, 105648
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(2024):
Proteogenomic Data Integration Reveals CXCL10 as a Potentially Downstream Causal Mediator for IL-6 Signaling on Atherosclerosis.
In: Circulation, Bd. 149, Nr. 9: S. 669-683
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Qu, Kang; Li, Ming-xi; Yu, Peng; Palotie, Aarno; Pressman, Alice; Belin, Andrea C.; Bjornsdottir, Anna; Maagdenberg, Arn M. J. M. van den; Harder, Aster V. E.; Winsvold, Bendik S.; Müller-Myhsok, Bertram; Cormand, Bru; Ran, Caroline; Northover, Carrie; Kubisch, Christian; Duijn, Cornelia van; Nyholt, Dale R.; Chasman, Daniel I.; Posthuma, Danielle; Lessel, Davor; Boomsma, Dorret I.; Hämäläinen, Eija; Kristoffersen, Espen S.; Cuenca-Leon, Ester; Davey-Smith, George; Terwindt, Gisela M.; Sigurdardottir, Gudrun R.; Bjornsdottir, Gyda; Hautakangas, Heidi; Stefansson, Hreinn; de Boer, Irene; Kaprio, Jaakko; Olesen, Jes; Zwart, John-Anker; Stefansson, Kari; Ligthart, Lannie; Launer, Lenore; Pedersen, Linda M.; Kogelman, Lisette J. A.; Griffiths, Lyn R.; Ikram, M. Arfan; Wessman, Maija; Kaunisto, Mari; Hrafnsdottir, Maria G.; Hiekkala, Marjo; Järvelin, Marjo-Riitta; Dichgans, Martin; Pirinen, Matti; Kallela, Mikko; Kurki, Mitja; Chalmer, Mona A.; Pedersen, Nancy; Sveinsson, Olafur A.; Raitakari, Olli; Gormley, Padhraig; Pozo-Rosich, Patricia; Palta, Priit; Malik, Rainer; Kajanne, Risto; Børte, Sigrid; Magnusson, Sigurdur H.; Lehtimäki, Terho; Hansen, Thomas F.; Thorgeirsson, Thorgeir E.; Freilinger, Tobias; Kurth, Tobias; Esko, Tonu; Anttila, Verneri; Artto, Ville; Wu, Bai-hua; Shi, Miao und Dong, Ming
(2024):
HMG-CoA reductase is a potential therapeutic target for migraine: a mendelian randomization study.
In: Scientific Reports, Bd. 14, Nr. 1, 12094
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Ruch, Francois; Gnoerich, Johannes; Wind, Karin; Koehler, Mara; Zatcepin, Artem; Wiedemann, Thomas; Gildehaus, Franz-Joseph; Lindner, Simon; Boening, Guido; von Ungern-Sternberg, Barbara; Beyer, Leonie; Herms, Jochen; Bartenstein, Peter; Brendel, Matthias und Eckenweber, Florian
(2024):
Validity and value of metabolic connectivity in mouse models of β-amyloid and tauopathy.
In: Neuroimage, Bd. 286, 120513
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Fornix fractional anisotropy mediates the association between Mediterranean diet adherence and memory four years later in older adults without dementia.
In: Neurobiology of Aging, Bd. 136: S. 99-110
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(2024):
Carotid Plaque-RADS A Novel Stroke Risk Classification System.
In: JACC-Cardiovascular Imaging, Bd. 17, Nr. 1: S. 62-75
Sadlon, A.; Takousis, P.; Evangelou, E.; Prokopenko, I.; Alexopoulos, P.; Udeh-Momoh, C.-M.; Price, G.; Middleton, L. und Perneczky, Robert
(2024):
Association of Blood MicroRNA Expression and Polymorphisms with Cognitive and Biomarker Changes in Older Adults.
In: Jpad-Journal of Prevention of Alzheimers Disease, Bd. 11, Nr. 1: S. 230-240
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(2024):
Association of Chronic Pain with Biomarkers of Neurodegeneration, Microglial Activation, and Inflammation in Cerebrospinal Fluid and Impaired Cognitive Function.
In: Annals of Neurology, Bd. 95, Nr. 1: S. 195-206
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(2024):
Extending the phenotypic spectrum assessed by the CDR plus NACC FTLD in genetic frontotemporal dementia.
In: Alzheimer's & Dementia: Diagnosis, Assessment & Disease Monitoring, Bd. 16, Nr. 2, e12571
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Scekic-Zahirovic, Jelena; Benetton, Cristina; Brunet, Aurore; Ye, Xiaoqian; Logunov, Evgeny; Douchamps, Vincent; Megat, Salim; Andry, Virginie; Kan, Vanessa Wing Yin; Stuart-Lopez, Geoffrey; Gilet, Johan; Guillot, Simon J.; Dirrig-Grosch, Sylvie; Gorin, Charlotte; Trombini, Margaux; Dieterle, Stephane; Sinniger, Jerome; Fischer, Mathieu; Rene, Frederique; Gunes, Zeynep; Kessler, Pascal; Dupuis, Luc; Pradat, Pierre-Francois; Goumon, Yannick; Goutagny, Romain; Marchand-Pauvert, Veronique; Liebscher, Sabine und Rouaux, Caroline
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Cortical hyperexcitability in mouse models and patients with amyotrophic lateral sclerosis is linked to noradrenaline deficiency.
In: Science Translational Medicine, Bd. 16, Nr. 738, eadg3665
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Shojaei, Monireh; Zhou, Qihui; Palumbo, Giovanna; Schaefer, Rebecca; Kaskinoro, Janne; Vehmaan-Kreula, Pirjo; Bartenstein, Peter; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843; Edbauer, Dieter und Lindner, Simon ORCID: https://orcid.org/0009-0007-4379-4436
(2024):
Development and Preclinical Evaluation of a Copper-64-Labeled Antibody Targeting Glycine-Alanine Dipeptides for PET Imaging of C9orf72-Associated Amyotrophic Lateral Sclerosis/Frontotemporal Dementia.
In: ACS Pharmacology & Translational Science, Bd. 7, Nr. 5: S. 1404-1414
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Shrouder, Joshua James; Calandra, Gian Marco; Filser, Severin; Varga, Daniel Peter; Besson-Girard, Simon; Mamrak, Uta; Dorok, Maximilian; Bulut-Impraim, Buket; Seker, Fatma Burcu; Gesierich, Benno; Laredo, Fabio; Wehn, Antonia Clarissa; Khalin, Igor; Bayer, Patrick; Liesz, Arthur; Gokce, Ozgun und Plesnila, Nikolaus
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Continued dysfunction of capillary pericytes promotes no-reflow after experimental stroke in vivo.
In: Brain, Bd. 147, Nr. 3: S. 1057-1074
Sonsalla, Giovanna; Malpartida, Ana Belen; Riedemann, Therese; Gusic, Mirjana; Rusha, Ejona; Bulli, Giorgia; Najas, Sonia; Janjic, Aleks; Hersbach, Bob A.; Smialowski, Pawel; Drukker, Micha; Enard, Wolfgang; Prehn, Jochen H. M.; Prokisch, Holger; Goetz, Magdalena und Masserdotti, Giacomo
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Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle.
In: Neuron, Bd. 112, Nr. 7
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CHD8-related disorders redefined: an expanding spectrum of dystonic phenotypes.
In: Journal of Neurology, Bd. 271, Nr. 5: S. 2859-2865
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Myoclonus and Dystonia as Recurrent Presenting Features in Patients with the SCA21-Associated TMEM240 p.Pro170Leu Variant.
In: Tremor and Other Hyperkinetic Movements, Bd. 14, Nr. 1, 16: S. 1-9
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Ambient sound stimulation tunes axonal conduction velocity by regulating radial growth of myelin on an individual, axon- by- axon basis.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 121, Nr. 11, e2316439121
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Metabolic network alterations as a supportive biomarker in dementia with Lewy bodies with preserved dopamine transmission.
In: European Journal of Nuclear Medicine and Molecular Imaging, Bd. 51, Nr. 4: S. 1023-1034
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Strohm, Lea; Daiber, Andreas; Ubbens, Henning; Krishnankutty, Roopesh; Oelze, Matthias; Kuntic, Marin; Hahad, Omar; Klein, Veronique; Hoefer, Imo E.; von Kriegsheim, Alex; Kleinert, Hartmut; Atzler, Dorothee; Lurz, Philipp; Weber, Christian; Wild, Philipp S.; Muenzel, Thomas; Knosalla, Christoph; Lutgens, Esther und Daub, Steffen
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Role of inflammatory signaling pathways involving the CD40-CD40L-TRAF cascade in diabetes and hypertension-insights from animal and human studies.
In: Basic Research in Cardiology
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Tahedl, Marlene; Wiltgen, Tun; Voon, Cui Ci; Berthele, Achim; Kirschke, Jan S.; Hemmer, Bernhard; Muehlau, Mark; Zimmer, Claus und Wiestler, Benedikt
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Cortical Thin Patch Fraction Reflects Disease Burden in MS: The Mosaic Approach.
In: American Journal of Neuroradiology, Bd. 45, Nr. 1: S. 82-89
Tatenhorst, Lars; Maass, Fabian; Paul, Hannah; Dambeck, Vivian; Baehr, Mathias; Dono, Rosanna und Lingor, Paul
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Glypican-4 serum levels are associated with cognitive dysfunction and vascular risk factors in Parkinson's disease.
In: Scientific Reports, Bd. 14, Nr. 1, 5005
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Association of latent factors of neuroinflammation with Alzheimer's disease pathology and longitudinal cognitive decline.
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In: Nature Aging, Bd. 4, Nr. 4
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FARS-ADL across Ataxias: Construct Validity, Sensitivity to Change, and Minimal Important Change.
In: Movement Disorders
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EANM practice guidelines for an appropriate use of PET and SPECT for patients with epilepsy.
In: European Journal of Nuclear Medicine and Molecular Imaging
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Targeting TGFβ-activated kinase-1 activation in microglia reduces CAR T immune effector cell-associated neurotoxicity syndrome.
In: Nature Cancer [Forthcoming]
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T cell specific deletion of Casitas B lineage lymphoma-b reduces atherosclerosis, but increases plaque T cell infiltration and systemic T cell activation.
In: Frontiers in Immunology, Bd. 15, 1297893
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Investigation of sex differences in mutation carriers of the Dominantly Inherited Alzheimer Network.
In: Alzheimers & Dementia, Bd. 20, Nr. 1: S. 47-62
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Downstream Biomarker Effects of Gantenerumab or Solanezumab in Dominantly Inherited Alzheimer Disease.
In: JAMA Neurology, Bd. 81, Nr. 6: S. 582-593
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European stroke organisation (ESO) guideline on cerebral small vessel disease, part 2, lacunar ischaemic stroke.
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EANM position on positron emission tomography in suspected functional pituitary neuroendocrine tumours.
In: European Journal of Nuclear Medicine and Molecular Imaging [Forthcoming]
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IL-23 stabilizes an effector Treg cell program in the tumor microenvironment.
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Retinal small vessel pathology is associated with disease burden in multiple sclerosis.
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Effects of tofersen treatment in patients with SOD1-ALS in a real-world setting - a 12-month multicenter cohort study from the German early access program.
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LST-AI: A deep learning ensemble for accurate MS lesion segmentation.
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Comparison of tau spread in people with Down syndrome versus autosomal-dominant Alzheimer's disease: a cross-sectional study.
In: Lancet Neurology, Bd. 23, Nr. 5: S. 500-510
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Optical coherence tomography angiography suggests different retinal pathologies in multiple sclerosis and Sjögren’s syndrome.
In: Journal of Neurology [Forthcoming]
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Wolff, Andreas W.; Bidner, Helen; Remane, Yvonne; Zimmer, Janine; Aarsland, Dag; Rascol, Olivier; Wyse, Richard K.; Hapfelmeier, Alexander und Lingor, Paul
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Protocol for a randomized, placebo-controlled, double-blind phase IIa study of the safety, tolerability, and symptomatic efficacy of the ROCK-inhibitor Fasudil in patients with Parkinson's disease (ROCK-PD).
In: Frontiers in Aging Neuroscience, Bd. 16, 1308577
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Low-intensity vestibular noise stimulation improves postural symptoms in progressive supranuclear palsy.
In: Journal of Neurology [Forthcoming]
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Xu, Meng; Ito-Kureha, Taku; Kang, Hyun-Seo; Chernev, Aleksandar; Raj, Timsse; Hoefig, Kai P.; Hohn, Christine; Giesert, Florian; Wang, Yinhu; Pan, Wenliang; Zietara, Natalia; Straub, Tobias; Feederle, Regina; Daniel, Carolin; Adler, Barbara; Koenig, Julian; Feske, Stefan; Tsokos, George C.; Wurst, Wolfgang; Urlaub, Henning; Sattler, Michael; Kisielow, Jan; Wulczyn, F. Gregory; Lyszkiewicz, Marcin und Heissmeyer, Vigo
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The thymocyte-specific RNA-binding protein Arpp21 provides TCR repertoire diversity by binding to the 3'-UTR and promoting Rag1 mRNA expression.
In: Nature Communications, Bd. 15, Nr. 1, 2194
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Ye, Lan; Greten, Stephan; Wegner, Florian; Doll-Lee, Johanna; Krey, Lea; Heine, Johanne; Gandor, Florin; Vogel, Annemarie; Berger, Luise; Gruber, Doreen; Levin, Johannes; Katzdobler, Sabrina; Peters, Oliver; Dashti, Eman; Priller, Josef; Spruth, Eike Jakob; Kuehn, Andrea A.; Krause, Patricia; Spottke, Annika; Schneider, Anja; Beyle, Aline; Kimmich, Okka; Donix, Markus; Haussmann, Robert; Brandt, Moritz; Dinter, Elisabeth; Wiltfang, Jens; Schott, Bjoern H.; Zerr, Inga; Baehr, Mathias; Buerger, Katharina; Janowitz, Daniel; Perneczky, Robert; Rauchmann, Boris-Stephan; Weidinger, Endy; Duezel, Emrah; Glanz, Wenzel; Teipel, Stefan; Kilimann, Ingo; Wurster, Isabel; Brockmann, Kathrin; Hoffmann, Daniel C.; Klockgether, Thomas; Krause, Olaf; Heck, Johannes; Hoeglinger, Guenter U. und Klietz, Martin
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The comorbidity profiles and medication issues of patients with multiple system atrophy: a systematic cross-sectional analysis.
In: Journal of Neurology, Bd. 271, Nr. 5: S. 2639-2648
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Yu, Chen; Lad, Eleonora M.; Mathew, Rose; Shiraki, Nobuhiko; Littleton, Sejiro; Chen, Yun; Hou, Jinchao; Schlepckow, Kai; Degan, Simone; Chew, Lindsey; Amason, Joshua; Kalnitsky, Joan; Bowes Rickman, Catherine; Proia, Alan D.; Colonna, Marco; Haass, Christian und Saban, Daniel R.
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Microglia at sites of atrophy restrict the progression of retinal degeneration via galectin-3 and Trem2.
In: Journal of Experimental Medicine, Bd. 221, Nr. 3, e20231011
Yu-Wai-Man, Patrick; Carelli, Valerio; Newman, Nancy J.; Silva, Magda Joana; Linden, Aki; Van Stavern, Gregory; Szaflik, Jacek P.; Banik, Rudrani; Lubinski, Wojciech; Pemp, Berthold; Liao, Yaping Joyce; Subramanian, Prem S.; Misiuk-Hojlo, Marta; Newman, Steven; Castillo, Lorena; Kociecki, Jaroslaw; Levin, Marc H.; Munoz-Negrete, Francisco Jose; Yagan, Ali; Cherninkova, Sylvia; Katz, David; Meunier, Audrey; Votruba, Marcela; Korwin, Magdalena; Dziedziak, Jacek; Jurkute, Neringa; Harvey, Joshua P.; La Morgia, Chiara; Priglinger, Claudia; Lloria, Xavier; Tomasso, Livia und Klopstock, Thomas
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Therapeutic benefit of idebenone in patients with Leber hereditary optic neuropathy: The LEROS nonrandomized controlled trial.
In: Cell Reports Medicine, Bd. 5, Nr. 3, 101437
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Zatcepin, Artem; Kopczak, Anna; Holzgreve, Adrien ORCID: https://orcid.org/0000-0002-9566-8438; Hein, Sandra; Schindler, Andreas; Duering, Marco; Kaiser, Lena; Lindner, Simon; Schidlowski, Martin; Bartenstein, Peter; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Brendel, Matthias ORCID: https://orcid.org/0000-0002-9247-2843 und Ziegler, Sibylle I.
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Machine learning-based approach reveals essential features for simplified TSPO PET quantification in ischemic stroke patients.
In: Zeitschrift für Medizinische Physik, Bd. 34, Nr. 2: S. 218-230
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2023
Afzali, Ali M.; Moog, Philipp; Kalluri, Sudhakar Reddy; Hofauer, Benedikt; Knopf, Andreas; Kirschke, Jan Stefan; Hemmer, Bernhard und Berthele, Achim
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CNS demyelinating events in primary Sjogren's syndrome: A single-center case series on the clinical phenotype.
In: Frontiers in Neurology, Bd. 14, 1128315
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Aggarwal, Abhi; Liu, Rui; Chen, Yang J.; Ralowicz, Amelia J. J.; Bergerson, Samuel J.; Tomaska, Filip; Mohar, Boaz L.; Hanson, Timothy L. P.; Hasseman, Jeremy P.; Reep, Daniel; Tsegaye, Getahun; Yao, Pantong; Ji, Xiang; Kloos, Marinus; Walpita, Deepika; Patel, Ronak A.; Mohr, Manuel A. W.; Tillberg, Paul W. L.; Looger, Loren L. S.; Marvin, Jonathan S. B.; Hoppa, Michael B.; Konnerth, Arthur; Kleinfeld, David R.; Schreiter, Eric R. und Podgorski, Kaspar
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Glutamate indicators with improved activation kinetics and localization for imaging synaptic transmission.
In: Nature Methods, Bd. 20, Nr. 6:
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Persistent virus-specific and clonally expanded antibody-secreting cells respond to induced self-antigen in the CNS.
In: Acta Neuropathologica, Bd. 145, Nr. 3: S. 335-355
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(2023):
Prognostic Value of TSPO PET Before Radiotherapy in Newly Diagnosed IDH-Wild-Type Glioblastoma.
In: Journal of Nuclear Medicine, Bd. 64, Nr. 10: S. 1519-1525
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Synaptogenic gene therapy with FGF22 improves circuit plasticity and functional recovery following spinal cord injury.
In: EMBO Molecular Medicine, Bd. 15, Nr. 2
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Semaphorin 4B is an ADAM17-cleaved adipokine that inhibits adipocyte differentiation and thermogenesis.
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Spatial Transcriptomics-correlated Electron Microscopy maps transcriptional and ultrastructural responses to brain injury.
In: Nature Communications, Bd. 14, Nr. 1
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Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease.
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Hemispheric analysis of mitochondrial Complex I and II activity in the mouse model of ischemia-reperfusion-induced injury.
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Genetic Risk Score for Intracranial Aneurysms: Prediction of Subarachnoid Hemorrhage and Role in Clinical Heterogeneity.
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Linking early-life bilingualism and cognitive advantage in older adulthood.
In: Neurobiology of Aging, Bd. 124: S. 18-28
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[18F]F-DED PET imaging of reactive astrogliosis in neurodegenerative diseases: preclinical proof of concept and first-in-human data.
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Deciphering sources of PET signals in the tumor microenvironment of glioblastoma at cellular resolution.
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(2023):
Visualizing the activation of encephalitogenic T cells in the ileal lamina propria by in vivo two- photon imaging.
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Arterial hypertension and β-amyloid accumulation have spatially overlapping effects on posterior white matter hyperintensity volume: a cross-sectional study.
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A unified classification approach rating clinical utility of protein biomarkers across neurologic diseases.
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sTREM2 is associated with amyloid-related p-tau increases and glucose hypermetabolism in Alzheimer's disease.
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Antibodies Against Glutamic Acid Decarboxylase 65 Are Locally Produced in the CSF and Arise During Affinity Maturation.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 10, Nr. 3, e200090
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The potential clinical value of plasma biomarkers in Alzheimer's disease.
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Structural MRI predicts clinical progression in presymptomatic genetic frontotemporal dementia: findings from the GENetic Frontotemporal dementia Initiative cohort.
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(2023):
Serum IL-6, sAXL, and YKL-40 as systemic correlates of reduced brain structure and function in Alzheimer’s disease: results from the DELCODE study.
In: Alzheimer's Research & Therapy
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(2023):
Automatic covariance pattern analysis outperforms visual reading of 18F-fluorodeoxyglucose-positron emission tomography (FDG-PET) in variant progressive supranuclear palsy.
In: Movement Disorders, Bd. 38, Nr. 10: S. 1901-1913
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PSMA-Expression Is Highly Associated with Histological Subtypes of Renal Cell Carcinoma: Potential Implications for Theranostic Approaches.
In: Biomedicines, Bd. 11, Nr. 11, 3095
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Bussy, Aurelie P.; Levy, Jake P.; Best, Tristin; Patel, Raihaan; Cupo, Lani; Van Langenhove, Tim; Nielsen, Jorgen E.; Pijnenburg, Yolande; Waldo, Maria Landqvist M.; Remes, Anne M. L.; Schroeter, Matthias L.; Santana, Isabel; Pasquier, Florence; Otto, Markus; Danek, Adrian; Levin, Johannes; Le Ber, Isabelle; Vandenberghe, Rik; Synofzik, Matthis; Moreno, Fermin; de Mendonca, Alexandre; Sanchez-Valle, Raquel; Laforce, Robert; Langheinrich, Tobias; Gerhard, Alexander; Graff, Caroline R.; Butler, Chris R.; Sorbi, Sandro; Jiskoot, Lize; Seelaar, Harro C.; van Swieten, John C.; Finger, Elizabeth; Tartaglia, Maria Carmela; Masellis, Mario; Tiraboschi, Pietro; Galimberti, Daniela; Borroni, Barbara B.; Rowe, James B.; Bocchetta, Martina D.; Rohrer, Jonathan D. A.; Devenyi, Gabriel A.; Chakravarty, M. Mallar und Ducharme, Simon
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Cerebellar and subcortical atrophy contribute to psychiatric symptoms in frontotemporal dementia.
In: Human Brain Mapping, Bd. 44, Nr. 7: S. 2684-2700
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(2023):
Letter to the Editor: Novel TREM2 frameshift mutation in a 30-year-old woman with suspected frontotemporal dementia.
In: Neurological Sciences, Bd. 44, Nr. 7: S. 2581-2585
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Cai, Ruiyao; Kolabas, Zeynep Ilgin; Pan, Chenchen; Mai, Hongcheng; Zhao, Shan; Kaltenecker, Doris; Voigt, Fabian F.; Molbay, Muge; Ohn, Tzu-lun; Vincke, Cecile; Todorov, Mihail I.; Helmchen, Fritjof; Van Ginderachter, Jo A. und Ertuerk, Ali
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Whole-mouse clearing and imaging at the cellular level with vDISCO.
In: Nature Protocols, Bd. 18, Nr. 4:
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Calligaris, Matteo; Yang, Chun Y.; Bonelli, Simone; Spano, Donatella Pia; Mueller, Stephan A.; Lichtenthaler, Stefan F.; Troeberg, Linda und Scilabra, Simone D.
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Identification of membrane proteins regulated by ADAM15 by SUSPECS proteomics.
In: Frontiers in Molecular Biosciences, Bd. 10, 1162504
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Carbo-Tano, Martin; Lapoix, Mathilde; Jia, Xinyu; Thouvenin, Olivier; Pascucci, Marco; Auclair, Francois; Quan, Feng B.; Albadri, Shahad; Aguda, Vernie; Farouj, Younes; Hillman, Elizabeth M. C.; Portugues, Ruben; Del Bene, Filippo; Thiele, Tod R.; Dubuc, Rejean und Wyart, Claire
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The mesencephalic locomotor region recruits V2a reticulospinal neurons to drive forward locomotion in larval zebrafish.
In: Nature Neuroscience, Bd. 26, Nr. 10:
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Ceanga, Mihai; Rahmati, Vahid; Haselmann, Holger; Schmidl, Lars; Hunter, Daniel; Brauer, Anna-Katherina; Liebscher, Sabine; Kreye, Jakob; Pruess, Harald; Groc, Laurent; Hallermann, Stefan; Dalmau, Josep; Ori, Alessandro; Heckmann, Manfred und Geis, Christian
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Human NMDAR autoantibodies disrupt excitatory-inhibitory balance, leading to hippocampal network hypersynchrony.
In: Cell Reports, Bd. 42, Nr. 10, 113166
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Cimen, Ismail; Natarelli, Lucia; Kichi, Zahra Abedi; Henderson, James M.; Farina, Floriana M.; Briem, Eva; Aslani, Maria; Megens, Remco T. A.; Jansen, Yvonne; Mann-Fallenbuchel, Elizabeth; Gencer, Selin; Duchene, Johan; Nazari-Jahantigh, Maliheh; van der Vorst, Emiel P. C.; Enard, Wolfgang; Doering, Yvonne; Schober, Andreas; Santovito, Donato und Weber, Christian
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Targeting a cell-specific microRNA repressor of CXCR4 ameliorates atherosclerosis in mice.
In: Science Translational Medicine, Bd. 15, Nr. 720, eadf3357
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Coenen, Mirthe; Biessels, Geert Jan; DeCarli, Charles; Fletcher, Evan F.; Maillard, Pauline M.; Barkhof, Frederik; Barnes, Josephine; Benke, Thomas; Boomsma, Jooske M. F.; Chen, Christopher P. L. H.; Dal-Bianco, Peter; Dewenter, Anna; Duering, Marco; Enzinger, Christian; Ewers, Michael; Exalto, Lieza G.; Franzmeier, Nicolai; Groeneveld, Onno; Hilal, Saima; Hofer, Edith; Koek, Huiberdina L.; Maier, Andrea B.; McCreary, Cheryl R.; Papma, Janne M.; Paterson, Ross W.; Pijnenburg, Yolande A. L.; Rubinski, Anna; Schmidts, Reinhold; Schott, Jonathan M.; Slattery, Catherine F.; Smith, Eric E.; Sudre, Carole H.; Steketee, Rebecca M. E.; Berg, Esther van den; Flier, Wiesje M. van der; Venketasubramanian, Narayanaswamy; Vernoo, Meike W.; Wolters, Frank J.; Xin, Xu; Biesbrok, J. Matthijs und Kuijf, Hugo J.
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Spatial distributions of white matter hyperintensities on brain MRI: A pooled analysis of individual participant data from 11 memory clinic cohorts.
In: Neuroimage-Clinical, Bd. 40, 103547
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Conrad, Julian ORCID: https://orcid.org/0000-0001-7912-0571; Baier, Bernhard ORCID: https://orcid.org/0000-0003-0793-0350; Eberle, Laurenz; Ruehl, Ria Maxine; Boegle, Rainer; Zwergal, Andreas und Dieterich, Marianne
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Network Architecture of Verticality Processing in the Human Thalamus.
In: Annals of Neurology, Bd. 94, Nr. 1: S. 133-145
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Cordts, Isabell; Wachinger, Annika; Scialo, Carlo; Lingor, Paul; Polymenidou, Magdalini; Buratti, Emanuele und Feneberg, Emily
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TDP-43 Proteinopathy Specific Biomarker Development.
In: Cells, Bd. 12, Nr. 4, 597
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(2023):
Extreme phenotypic heterogeneity in non-expansion spinocerebellar ataxias.
In: American Journal of Human Genetics, Bd. 110, Nr. 7:
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Dawkins, Edgar; Derks, Rico J. E.; Schifferer, Martina; Trambauer, Johannes; Winkler, Edith; Simons, Mikael; Paquet, Dominik; Giera, Martin; Kamp, Frits und Steiner, Harald
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Membrane lipid remodeling modulates γ-secretase processivity.
In: Journal of Biological Chemistry, Bd. 299, Nr. 4, 103027
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Biodistribution and dosimetry for combined [177Lu]Lu-PSMA-I&T/[225Ac]Ac-PSMA-I&T therapy using multi-isotope quantitative SPECT imaging.
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Challenges in Establishing the Diagnosis of PRRT2-Related Dystonia: Recurrent Pathogenic Variants in a Homopolymeric Stretch.
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Tissue Inhibitor of Metalloproteinases-1 Interacts with CD74 to Promote AKT Signaling, Monocyte Recruitment Responses, and Vascular Smooth Muscle Cell Proliferation.
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The genetic etiology of periodic limb movement in sleep.
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MOG-IgG-Associated Bilateral Optic Neuritis in Temporal Relation to Monkeypox Vaccination.
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A Residual Marker of Cognitive Reserve Is Associated with Resting-State Intrinsic Functional Connectivity Along the Alzheimer's Disease Continuum.
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Endovascular thrombectomy for basilar artery occlusion stroke: Analysis of the German Stroke Registry‐Endovascular Treatment.
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NEMO reshapes the α-Synuclein aggregate interface and acts as an autophagy adapter by co-condensation with p62.
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A Genetic Risk Variant for Multiple Sclerosis Severity is Associated with Brain Atrophy.
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Validation of the test for finding word retrieval deficits (WoFi) in detecting Alzheimer's disease in a naturalistic clinical setting.
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Single-cell transcriptomic atlas-guided development of CAR-T cells for the treatment of acute myeloid leukemia.
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Discovery of an inhibitor of DNA-driven inflammation that preferentially targets the AIM2 inflammasome.
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Microglia-mediated demyelination protects against CD8+ T cell-driven axon degeneration in mice carrying PLP defects.
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Exome-based gene panel analysis in a cohort of acute juvenile ischemic stroke patients:relevance of NOTCH3 and GLA variants.
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Bony Stroke: Ischemic Stroke Caused by Mechanical Stress on Brain Supplying Arteries From Anatomical Bone or Cartilage Anomalies.
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Retrospective cohort study to devise a treatment decision score predicting adverse 24-month radiological activity in early multiple sclerosis.
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Epigenetic Association Analyses and Risk Prediction of RLS.
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Recessive NUP54 Variants Underlie Early-Onset Dystonia with Striatal Lesions.
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Dystonia Linked to EIF4A2 Haploinsufficiency: A Disorder of Protein Translation Dysfunction.
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Locus for severity implicates CNS resilience in progression of multiple sclerosis.
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A causal effects of gut microbiota in the development of migraine.
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Economic evaluation of Motor Neuron Diseases: a nationwide cross-sectional analysis in Germany.
In: Journal of Neurology, Bd. 270, Nr. 10: S. 4922-4938
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Exploring the ATN classification system using brain morphology.
In: Alzheimers Research & Therapy, Bd. 15, Nr. 1, 50
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Efficacy and Safety of Proposed Biosimilar Natalizumab (PB006) in Patients With Relapsing-Remitting Multiple Sclerosis The Antelope Phase 3 Randomized Clinical Trial.
In: JAMA Neurology, Bd. 80, Nr. 3: S. 298-307
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Loss of TDP-43 causes ectopic endothelial sprouting and migration defects through increased fibronectin, vcam 1 and integrin α4/β1.
In: Frontiers in Cell and Developmental Biology, Bd. 11, 1169962
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Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage.
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Ocrelizumab Treatment Modulates B-Cell Regulating Factors in Multiple Sclerosis.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 10, Nr. 2, e200083
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Uncovering distinct progression patterns of tau deposition in progressive supranuclear palsy using [18F]Florzolotau PET imaging and subtype/stage inference algorithm.
In: Ebiomedicine, Bd. 97, 104835
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Markers of Vitamin B12 Status in Relation to Cerebrospinal Fluid Biomarkers of Alzheimer's Disease and Cognitive Performance.
In: Annals of Neurology, Bd. 94, Nr. 2: S. 223-231
Horie, Kanta; Li, Yan R.; Barthelemy, Nicolas; Gordon, Brian; Hassenstab, Jason; Benzinger, Tammie L. S. M.; Fagan, Anne C.; Morris, John M.; Karch, Celeste; Xiong, Chengjie; Allegri, Ricardo; Mendez, Patricio Chrem; Ikeuchi, Takeshi; Kasuga, Kensaku; Noble, James; Farlow, Martin; Chhatwal, Jasmeer; Day, Gregory R.; Schofield, Peter R.; Masters, Colin; Levin, Johannes; Jucker, Mathias; Lee, Jae-Hong; Roh, Jee Hoon; Sato, Chihiro; Sachdev, Pallavi; Koyama, Akihiko; Reyderman, Larisa J.; Bateman, Randall und McDade, Eric
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Change in Cerebrospinal Fluid Tau Microtubule Binding Region Detects Symptom Onset, Cognitive Decline, Tangles, and Atrophy in Dominantly Inherited Alzheimer's Disease.
In: Annals of Neurology, Bd. 93, Nr. 6: S. 1158-1172
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High-Resolution RNA Sequencing from PFA-Fixed Microscopy Sections.
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Membrane Atg8ylation, stress granule formation, and MTOR regulation during lysosomal damage.
In: Autophagy, Bd. 19, Nr. 6, 2148900: S. 1893-1895
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Altered limbic functional connectivity in individuals with subjective cognitive decline: Converging and diverging findings across Chinese and German cohorts.
In: Alzheimers & Dementia, Bd. 19, Nr. 11: S. 4922-4934
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The Benson Complex Figure Test detects deficits in visuoconstruction and visual memory in symptomatic familial frontotemporal dementia: A GENFI study.
In: Journal of the Neurological Sciences, Bd. 446, 120590
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Cerebrospinal fluid proteomics define the natural history of autosomal dominant Alzheimer's disease.
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Neuron-oligodendrocyte potassium shuttling at nodes of Ranvier protects against.
In: Journal of Clinical Investigation, Bd. 133, Nr. 7, e164223
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Efficacy and Safety of Elamipretide in Individuals With Primary Mitochondrial Myopathy The MMPOWER-3 Randomized Clinical Trial.
In: Neurology, Bd. 101, Nr. 3, E238-E252
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The interplay between inflammatory cytokines and cardiometabolic disease: bi-directional mendelian randomisation study.
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Interplay Between Chronic Kidney Disease, Hypertension, and Stroke Insights From a Multivariable Mendelian Randomization Analysis.
In: Neurology, Bd. 101, Nr. 20, E1960-E1969
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A genome-wide in vivo CRISPR screen identifies essential regulators of T cell migration to the CNS in a multiple sclerosis model.
In: Nature Neuroscience, Bd. 26, Nr. 10:
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Dietary and supplemental intake of vitamins C and E is associated with altered DNA methylation in an epigenome-wide association study meta-analysis.
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Neurons on tape: Automated Tape Collecting Ultramicrotomy-mediated volume EM for targeting neuropathology.
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The impact of disease-modifying therapies on immunoglobulin blood levels in patients with multiple sclerosis: a retrospective cross-sectional study.
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Regulatory and coding sequences of TRNP1 co-evolve with brain size and cortical folding in mammals.
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Long-term environmental enrichment is associated with better fornix microstructure in older adults.
In: Frontiers in Aging Neuroscience, Bd. 15, 1170879
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APOE and immunity: Research highlights.
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Neuropathology of incidental Lewy body & prodromal Parkinson's disease.
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Real-world operation of multiple sclerosis centres in Central-Eastern European countries covering 107 million inhabitants.
In: Multiple Sclerosis and Related Disorders, Bd. 69, 104406
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Distinct molecular profiles of skull bone marrow in health and neurological disorders.
In: Cell, Bd. 186, Nr. 17, 3706-3725.e29
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The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.
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Effect of blood pressure-lowering agents on microvascular function in people with small vessel diseases (TREAT-SVDs): a multicentre, open-label, randomised, crossover trial.
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European Committee for Treatment and Research in Multiple Sclerosis and European Academy of Neurology consensus on vaccination in people with multiple sclerosis: Improving immunization strategies in the era of highly active immunotherapeutic drugs.
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Longitudinal Studies on Alzheimer Disease Mouse Models with Multiple Tracer PET/CT: Application of Reduction and Refinement Principles in Daily Practice to Safeguard Animal Welfare during Progressive Aging.
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Predictors of whole exome sequencing in dystonic cerebral palsy and cerebral palsy-like disorders.
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A microglial activity state biomarker panel differentiates FTD-granulin and Alzheimer's disease patients from controls.
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ATP2B2 de novo variants as a cause of variable neurodevelopmental disorders that feature dystonia, ataxia, intellectual disability, behavioral symptoms, and seizures.
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Nationwide Retrospective Analysis of Combinations of Advanced Therapies in Patients With Parkinson Disease.
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A reversible state of hypometabolism in a human cellular model of sporadic Parkinson's disease.
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PREDICT-juvenile-stroke: PRospective evaluation of a prediction score determining individual clinical outcome three months after ischemic stroke in young adults – a study protocol.
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Brain matters: unveiling the distinct contributions of region, age, and sex to glia diversity and CNS function.
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Copy number analysis from whole-exome sequencing data revealed a novel homozygous deletion in PARK7 leads to severe early-onset Parkinson's disease.
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Etiology of White Matter Hyperintensities in Autosomal Dominant and Sporadic Alzheimer Disease.
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POLR1A variants underlie phenotypic heterogeneity in craniofacial, neural, and cardiac anomalies.
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Differential diagnosis of suspected multiple sclerosis: an updated consensus approach.
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Speech Motor Profiles in Primary Progressive Aphasia.
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Relevance of Minor Neuropsychological Deficits in Patients With Subjective Cognitive Decline.
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ApoE4 and Connectivity-Mediated Spreading of Tau Pathology at Lower Amyloid Levels.
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Investigation of Shared Genetic Risk Factors Between Parkinson's Disease and Cancers.
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The OSCAR-MP Consensus Criteria for Quality Assessment of Retinal Optical Coherence Tomography Angiography.
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Perspective Review of Myeloid Immune Cell Responses and Poststroke Immunosuppression.
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Higher systolic blood pressure in early-mid adulthood is associated with poorer cognitive performance in those with a dominantly inherited Alzheimer's disease mutation but not in non-carriers. Results from the DIAN study.
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Migraine, chronic kidney disease and kidney function: observational and genetic analyses.
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Causal relationships between migraine and microstructural white matter: a Mendelian randomization study.
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Combined Connectomics, MAPT Gene Expression, and Amyloid Deposition to Explain Regional Tau Deposition in Alzheimer Disease.
In: Annals of Neurology
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Zibold, Julia; Lessard, Lola E. R.; Picard, Flavien; da Silva, Lara Gruijs; Zadorozhna, Yelyzaveta; Streichenberger, Nathalie; Belotti, Edwige; Osseni, Alexis; Emerit, Andrea; Errazuriz-Cerda, Elisabeth; Michel-Calemard, Laurence; Menassa, Rita; Coudert, Laurent; Wiessner, Manuela; Stucka, Rolf; Klopstock, Thomas; Simonetti, Francesca; Hutten, Saskia; Nonaka, Takashi; Hasegawa, Masato; Strom, Tim M.; Bernard, Emilien; Ollagnon, Elisabeth; Urtizberea, Andoni; Dormann, Dorothee; Petiot, Philippe; Schaeffer, Laurent; Senderek, Jan und Leblanc, Pascal
(2023):
The new missense G376V-TDP-43 variant induces late-onset distal myopathy but not amyotrophic lateral sclerosis.
In: Brain
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Ziegler, Karin A.; Ahles, Andrea; Dueck, Anne; Esfandyari, Dena; Pichler, Pauline; Weber, Karolin; Kotschi, Stefan; Bartelt, Alexander; Sinicina, Inga; Graw, Matthias; Leonhardt, Heinrich; Weckbach, Ludwig T.; Massberg, Steffen; Schifferer, Martina; Simons, Mikael; Hoeher, Luciano; Luo, Jie; Ertuerk, Ali; Schiattarella, Gabriele G.; Sassi, Yassine; Misgeld, Thomas und Engelhardt, Stefan
(2023):
Immune-mediated denervation of the pineal gland underlies sleep disturbance in cardiac disease.
In: Science, Bd. 381, Nr. 6655: S. 285-290
Zounek, Adrian Jun; Albert, Nathalie Lisa; Holzgreve, Adrien; Unterrainer, Marcus; Brosch-Lenz, Julia; Lindner, Simon; Bollenbacher, Andreas; Boening, Guido; Rupprecht, Rainer; Brendel, Matthias; von Baumgarten, Louisa; Tonn, Joerg-Christian; Bartenstein, Peter; Ziegler, Sibylle und Kaiser, Lena
(2023):
Feasibility of radiomic feature harmonization for pooling of [18F]FET or [18F]GE-180 PET images of gliomas.
In: Zeitschrift Fur Medizinische Physik, Bd. 33, Nr. 1: S. 91-102
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(2023):
A TREM2-activating antibody with a blood-brain barrier transport vehicle enhances microglial metabolism in Alzheimer's disease models.
In: Nature Neuroscience, Bd. 26, Nr. 3:
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(2023):
Hyperlipidaemia elicits an atypical, T helper 1–like CD4+ T-cell response: a key role for very low-density lipoprotein.
In: European Heart Journal Open, Bd. 3, Nr. 2
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2022
Ali, Muhammad M.; Sung, Yun Ju; Wang, Fengxian; Fernandez, Maria; Morris, John M.; Fagan, Anne; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella R.; Kleinberger, Gernot J.; Haass, Christian; Ewers, Michael; Levin, Johannes; Farlow, Martin; Perrin, Richard und Cruchaga, Carlos
(2022):
Leveraging large multi-center cohorts of Alzheimer disease endophenotypes to understand the role of Klotho heterozygosity on disease risk.
In: PLOS One
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(2022):
Brain Abnormalities in Patients with Germline Variants in H3F3: Novel Imaging Findings and Neurologic Symptoms Beyond Somatic Variants and Brain Tumors.
In: American Journal of Neuroradiology, Bd. 43, Nr. 7: S. 1048-1053
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(2022):
Dynamics of Retinal Vessel Loss After Acute Optic Neuritis in Patients With Relapsing Multiple Sclerosis.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 9, Nr. 3, e1159
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Mast Syndrome Outside the Amish Community: SPG21 in Europe.
In: Frontiers in Neurology, Bd. 12, 799953
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Case Series: Acute Hemorrhagic Encephalomyelitis After SARS-CoV-2 Vaccination.
In: Frontiers in Neurology, Bd. 12, 820049
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(11. April 2022):
Longitudinal [18]UCB-H/[18F]FDG imaging depicts complex patterns of structural and functional neuroplasticity following bilateral vestibular loss in the rat.
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Ganglioside lipidomics of CNS myelination using direct infusion shotgun mass spectrometry.
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IKKβ binds NLRP3 providing a shortcut to inflammasome activation for rapid immune responses.
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(17. Oktober 2022):
18 kDa translocator protein positron emission tomography facilitates early and robust tumor detection in the immunocompetent SB28 glioblastoma mouse model.
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New insights into the genetic etiology of Alzheimer's disease and related dementias.
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Glitter in the Darkness? Nonfibrillar beta-Amyloid Plaque Components Significantly Impact the beta-Amyloid PET Signal in Mouse Models of Alzheimer Disease.
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Combining tau-PET and fMRI meta-analyses for patient-centered prediction of cognitive decline in Alzheimer's disease.
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Chronic PPARγ Stimulation Shifts Amyloidosis to Higher Fibrillarity but Improves Cognition.
In: Frontiers in Aging Neuroscience, Bd. 14
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β-secretase inhibition prevents structural spine plasticity deficits in AppNL-G-F mice.
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Musical Activity During Life Is Associated With Multi-Domain Cognitive and Brain Benefits in Older Adults.
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Anomia is present pre-symptomatically in frontotemporal dementia due to MAPT mutations.
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Siponimod Inhibits the Formation of Meningeal Ectopic Lymphoid Tissue in Experimental Autoimmune Encephalomyelitis.
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Indirect Comparison of Lenadogene Nolparvovec Gene Therapy Versus Natural History in Patients with Leber Hereditary Optic Neuropathy Carrying the m.11778G > A MT-ND4 Mutation.
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The Boston criteria version 2.0 for cerebral amyloid angiopathy: a multicentre, retrospective, MRI-neuropathology diagnostic accuracy study.
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Plasma glial fibrillary acidic protein in autosomal dominant Alzheimer's disease: Associations with A beta-PET, neurodegeneration, and cognition.
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Variant-dependent heterogeneity in amyloid beta burden in autosomal dominant Alzheimer's disease: cross-sectional and longitudinal analyses of an observational study.
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White matter volume loss drives cortical reshaping after thalamic infarcts.
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Reorganization of sensory networks after subcortical vestibular infarcts: A longitudinal symptom-related voxel-based morphometry study.
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Successful treatment with azacitidine in VEXAS syndrome with prominent myofasciitis.
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Adult-Onset Neurodegeneration in Nucleotide Excision Repair Disorders (NERDND): Time to Move Beyond the Skin.
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Intrathecally Expanding B Cell Clones in Herpes Simplex Encephalitis: A Case Report.
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Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G(4)C(2))(n) expression in C9orf72 ALS/FTD.
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European Stroke Organisation (ESO) guideline on pharmacological interventions for long-term secondary prevention after ischaemic stroke or transient ischaemic attack.
In: European Stroke Journal, Bd. 7, Nr. 3:
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Cryptococcal Meningitis Reported With Fingolimod Treatment Case Series.
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Best practice approaches to outpatient management of people living with Parkinson's disease during the COVID-19 pandemic.
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The Interaction between HLA-DRB1 and Smoking in Parkinson's Disease Revisited.
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Dairy Intake and Parkinson's Disease: A Mendelian Randomization Study.
In: Movement Disorders, Bd. 37, Nr. 4: S. 857-864
Dormann, Dorothee und Behrends, Christian
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Only solid waste, please!
In: Molecular Cell, Bd. 82, Nr. 8: S. 1408-1410
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Ketogenic diet uncovers differential metabolic plasticity of brain cells.
In: Science Advances, Bd. 8, Nr. 37
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Genetic overlap between dystonia and other neurologic disorders: A study of 1,100 exomes.
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Properties and fate of human mesenchymal stem cells upon miRNA let-7f-promoted recruitment to atherosclerotic plaques.
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Determining the OPTIMAL DTI analysis method for application in cerebral small vessel disease.
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Selective plasticity of callosal neurons in the adult contralesional cortex following murine traumatic brain injury.
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Elevated CSF and plasma complement proteins in genetic frontotemporal dementia: results from the GENFI study.
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Signatures of glial activity can be detected in the CSF proteome.
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Lifelong experiences as a proxy of cognitive reserve moderate the association between connectivity and cognition in Alzheimer's disease.
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From novel discovery tools and biomarkers to precision medicine-basic cardiovascular science highlights of 2021/22.
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Atrial Fibrillation Risk Assessment after Embolic Stroke of Undetermined Source.
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Minor stroke in large vessel occlusion: A matched analysis of patients from the German Stroke Registry-Endovascular Treatment (GSR-ET) and patients from the Safe Implementation of Treatments in Stroke-International Stroke Thrombolysis Register (SITS-ISTR).
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Regional Associations of Cortical Superficial Siderosis and beta-Amyloid-Positron-Emission-Tomography Positivity in Patients With Cerebral Amyloid Angiopathy.
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AOPEP variants as a novel cause of recessive dystonia: Generalized dystonia and dystonia-parkinsonism.
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Structural brain splitting is a hallmark of Granulin-related frontotemporal dementia.
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Parkinson's disease motor symptoms rescue by CRISPRa-reprogramming astrocytes into GABAergic neurons.
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Genome-wide Association and Meta-analysis of Age at Onset in Parkinson Disease Evidence From the COURAGE-PD Consortium.
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Proteolytically generated soluble Tweak Receptor Fn14 is a blood biomarker for gamma-secretase activity.
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The C1q-ApoE complex: A new hallmark pathology of viral hepatitis and nonalcoholic fatty liver disease.
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Neuronal mitochondria transport Pink1 mRNA via synaptojanin 2 to support local mitophagy.
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A de novo BCL11B variant case manifesting with dystonic movement disorder regarding the article BCL11B-related disorder in two canadian children: Expanding the clinical phenotype (Prasad et al., 2020).
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The Role of Optical Coherence Tomography Criteria and Machine Learning in Multiple Sclerosis and Optic Neuritis Diagnosis.
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Dynamic tracing using ultra-bright labeling and multi-photon microscopy identifies endothelial uptake of poloxamer 188 coated poly(lactic-co-glycolic acid) nano-carriers in vivo.
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HOMER-3 Antibodies Were Not Detected in Two German Cohorts of Patients with Multiple System Atrophy.
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Complicated Carotid Artery Plaques and Risk of Recurrent Ischemic Stroke or TIA.
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Molecular Simulations Reveal Distinct Energetic and Kinetic Binding Properties of [F-18]PI-2620 on Tau Filaments from 3R/4R and 4R Tauopathies.
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Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease.
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Safety, tolerability and pharmacokinetics of the oligomer modulator anle138b with exposure levels sufficient for therapeutic efficacy in a murine Parkinson model: A randomised, double-blind placebo-controlled phase 1a trial.
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Regulatory T Cell-Related Gene Indicators in Pulmonary Hypertension.
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Longitudinal Cognitive Changes in Genetic Frontotemporal Dementia Within the GENFI Cohort.
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[PDF, 678kB]
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Cognitive composites for genetic frontotemporal dementia: GENFI-Cog.
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Impact of COVID-19 on multiple sclerosis care and management: Results from the European Committee for Treatment and Research in Multiple Sclerosis survey.
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REM sleep-active hypothalamic neurons may contribute to hippocampal social-memory consolidation.
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Mapping of neuroinflammation-induced hypoxia in the spinal cord using optoacoustic imaging.
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Microglial Activation and Connectivity in Alzheimer Disease and Aging.
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Post-Stroke Cognitive Impairment and Dementia.
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Multicenter F-18-PI-2620 PET for In Vivo Braak Staging of Tau Pathology in Alzheimer's Disease.
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Association between post-operative delirium and use of volatile anesthetics in the elderly: A real-world big data approach.
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Motor symptoms in genetic frontotemporal dementia: developing a new module for clinical rating scales.
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Innate Immune Pathways Promote Oligodendrocyte Progenitor Cell Recruitment to the Injury Site in Adult Zebrafish Brain.
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Primary cilia and SHH signaling impairments in human and mouse models of Parkinson's disease.
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Lipid and protein content profiling of isolated native autophagic vesicles.
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Effects of polygenic risk for major mental disorders and cross-disorder on cortical complexity.
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Development and evaluation of evidence-based patient information handbooks about multiple sclerosis immunotherapies.
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Broader Epstein-Barr virus-specific T cell receptor repertoire in patients with multiple sclerosis.
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Frequency and Longitudinal Course of Motor Signs in Genetic Frontotemporal Dementia.
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Determinants of functioning and health-related quality of life after vestibular stroke.
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Impact of Partial Volume Correction on [F-18]GE-180 PET Quantification in Subcortical Brain Regions of Patients with Corticobasal Syndrome.
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Seizures, ataxia and parvalbumin-expressing interneurons respond to selenium supply in Selenop-deficient mice.
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TPC2 rescues lysosomal storage in mucolipidosis type IV , Niemann–Pick type C1, and Batten disease.
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Utility of the Repeat and Point Test for Subtyping Patients With Primary Progressive Aphasia.
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Vps37a regulates hepatic glucose production by controlling glucagon receptor localization to endosomes.
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Long-term diazepam treatment enhances microglial spine engulfment and impairs cognitive performance via the mitochondrial 18 kDa translocator protein (TSPO).
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WARS2 mutations cause dopa-responsive early-onset parkinsonism and progressive myoclonus ataxia.
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Differential impairment of cerebrospinal fluid synaptic biomarkers in the genetic forms of frontotemporal dementia.
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Whole-Exome Sequencing Study of Consanguineous Parkinson's Disease Families and Related Phenotypes: Report of Twelve Novel Variants.
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Temporal order of clinical and biomarker changes in familial frontotemporal dementia.
In: Nature Medicine, Bd. 28, Nr. 10: S. 2194-2206
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Coordinated neurostimulation promotes circuit rewiring and unlocks recovery after spinal cord injury.
In: Journal of Experimental Medicine, Bd. 220, Nr. 3, e20220615
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DNAJC30 defect: a frequent cause of recessive Leber hereditary optic neuropathy and Leigh syndrome.
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Functional network segregation is associated with attenuated tau spreading in Alzheimer's disease.
In: Alzheimer's & Dementia
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Multi-omics profiling identifies a deregulated FUS-MAP1B axis in ALS/FTD–associated UBQLN2 mutants.
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COVID-19 Infection in Fingolimod- or Siponimod-Treated Patients: Case Series.
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Tissue Clearing Approaches in Atherosclerosis.
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Dystonia as a prominent feature of TCF20-associated neurodevelopmental disorder: Expanding the phenotype.
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A standardised methodology for the extraction and quantification of cell-free DNA in cerebrospinal fluid and application to evaluation of Alzheimer's disease and brain cancers.
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Designed peptides as nanomolar cross-amyloid inhibitors acting via supramolecular nanofiber co-assembly.
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Ca(V)2.1 channel mutations causing familial hemiplegic migraine type 1 increase the susceptibility for cortical spreading depolarizations and seizures and worsen outcome after experimental traumatic brain injury.
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CXCR4 and CD74 together enhance cell survival in response to macrophage migration-inhibitory factor in chronic lymphocytic leukemia.
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ExomeChip-based rare variant association study in restless legs syndrome.
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The risk of infections for multiple sclerosis and neuromyelitis optica spectrum disorder disease-modifying treatments: Eighth European Committee for Treatment and Research in Multiple Sclerosis Focused Workshop Review. April 2021.
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Amino Acid Uptake, Glucose Metabolism, and Neuroinflammation in John Cunningham Virus Associated Progressive Multifocal Leukoencephalopathy.
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Patterns and implications of neurological examination findings in autosomal dominant Alzheimer disease.
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Assessment of perfusion deficit with early phases of [F-18]PI-2620 tau-PET versus [F-18]flutemetamol-amyloid-PET recordings.
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De Novo and Dominantly Inherited SPTAN1 Mutations Cause Spastic Paraplegia and Cerebellar Ataxia.
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Combined Single-Cell RNA and Single-Cell α/β T Cell Receptor Sequencing of the Arterial Wall in Atherosclerosis.
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A Potential Citrate Shunt in Erythrocytes of PKAN Patients Caused by Mutations in Pantothenate Kinase 2.
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Blocking P2X7 by intracerebroventricular injection of P2X7-specific nanobodies reduces stroke lesions.
In: Journal of Neuroinflammation, Bd. 19, Nr. 1, 256
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Development of a sensitive trial-ready poly(GP) CSF biomarker assay for C9orf72-associated frontotemporal dementia and amyotrophic lateral sclerosis.
In: Journal of Neurology Neurosurgery and Psychiatry
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Wise, Rachel M.; Wagener, Annika; Fietzek, Urban M.; Klopstock, Thomas; Mosharov, Eugene V.; Zucca, Fabio A.; Sulzer, David; Zecca, Luigi und Burbulla, Lena F.
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Interactions of dopamine, iron, and alpha-synuclein linked to dopaminergic neuron vulnerability in Parkinson's disease and Neurodegeneration with Brain Iron Accumulation disorders.
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Fast versus slow disease progression in amyotrophic lateral sclerosis-clinical and genetic factors at the edges of the survival spectrum.
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Relevance of Subjective Cognitive Decline in Older Adults with a First-Degree Family History of Alzheimer's Disease.
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C5F glial markers are elevated in a subset of patients with genetic frontotemporal dementia.
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Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
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Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
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Quantitative Proteomics Reveals That ADAM15 Can Have Proteolytic-Independent Functions in the Steady State.
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Clinical implementation of RNA sequencing for Mendelian disease diagnostics.
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TDP-43 condensates and lipid droplets regulate the reactivity of microglia and regeneration after traumatic brain injury.
In: Nature Neuroscience, Bd. 25, Nr. 12: S. 1608-1625
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Reduced Acquisition Time [18F]GE-180 PET Scanning Protocol Replaces Gold-Standard Dynamic Acquisition in a Mouse Ischemic Stroke Model.
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Variants in Mitochondrial ATP Synthase Cause Variable Neurologic Phenotypes.
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Biallelic AOPEP Loss-of-Function Variants Cause Progressive Dystonia with Prominent Limb Involvement.
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Proteomic profiling in cerebral amyloid angiopathy reveals an overlap with CADASIL highlighting accumulation of HTRA1 and its substrates.
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Zhang, Xi; Wang, Zhihua; Zhang, Chuankai; Li, Yutao; Lu, Shu; Steffens, Sabine; Mohanta, Sarajo; Weber, Christian; Habenicht, Andreas und Yin, Changjun
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Laser Capture Microdissection–Based mRNA Expression Microarrays and Single-Cell RNA Sequencing in Atherosclerosis Research.
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Mapping autophagosome contents identifies interleukin-7 receptor-alpha as a key cargo modulating CD4+T cell proliferation.
In: Nature Communications, Bd. 13, Nr. 1, 5174
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Disease-linked TDP-43 hyperphosphorylation suppresses TDP-43 condensation and aggregation.
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Abudu, Yakubu Princely; Shrestha, Birendra Kumar; Zhang, Wenxin; Palara, Anthimi; Brenne, Hanne Britt; Larsen, Kenneth Bowitz; Wolfson, Deanna Lynn; Dumitriu, Gianina; Oie, Cristina Ionica; Ahluwalia, Balpreet Singh; Levy, Gahl; Behrends, Christian; Tooze, Sharon A.; Mouilleron, Stephane; Lamark, Trond und Johansen, Terje
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SAMM50 acts with p62 in piecemeal basal- and OXPHOS-induced mitophagy of SAM and MICOS components.
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Endothelial function in cardiovascular medicine: a consensus paper of the European Society of Cardioloy working Groups on Artherosclerosis and Vascular Biology, Aorta and Perirpheral Vascular Diseases, Coronary Pathophysiology and Microcirculation, and Thrombosis.
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Associations between APOE-, COMT Val108/158Met-and BDNF Val66Met polymorphisms and variations in depressive and anxiety symptoms, sense of coherence and vital exhaustion in the real-life setting of mandatory basic military training.
In: Journal of Neural Transmission, Bd. 128, Nr. 1: S. 105-114
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Optical coherence tomography angiography indicates subclinical retinal disease in neuromyelitis optica spectrum disorders.
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Bipolar multiplex families have an increased burden of common risk variants for psychiatric disorders.
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Markers of early changes in cognition across cohorts of adults with Down syndrome at risk of Alzheimer's disease.
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The gut microbiota modulates brain network connectivity under physiological conditions and after acute brain ischemia.
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Hyperexcitable interneurons trigger cortical spreading depression in an Scn1a migraine model.
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The RNA-binding protein FUS is chaperoned and imported into the nucleus by a network of import receptors.
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Mediterranean Diet, Alzheimer Disease Biomarkers, and Brain Atrophy in Old Age.
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Diabetes type 2 risk gene Dusp8 is associated with altered sucrose reward behavior in mice and humans.
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Microglia facilitate repair of demyelinated lesions via post-squalene sterol synthesis.
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Cognitive reserve hypothesis in frontotemporal dementia: A FDG-PET study.
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A comprehensive phenotypic characterization of a whole-body Wdr45 knock-out mouse.
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Long-Term Follow-Up After Unilateral Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy: The RESTORE Study.
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Quantitative Proteomics Reveals Changes Induced by TIMP-3 on Cell Membrane Composition and Novel Metalloprotease Substrates.
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Acid-Ion Sensing Channel 1a Deletion Reduces Chronic Brain Damage and Neurological Deficits after Experimental Traumatic Brain Injury.
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A Primeval Mechanism of Tolerance to Desiccation Based on Glycolic Acid Saves Neurons in Mammals from Ischemia by Reducing Intracellular Calcium-Mediated Excitotoxicity.
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The Aryl Hydrocarbon Receptor-Dependent TGF-α/VEGF-B Ratio Correlates With Disease Subtype and Prognosis in Multiple Sclerosis.
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Facing the urgency of therapies for progressive MS - a Progressive MS Alliance proposal.
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Davidson, Sean M.; Padro, Teresa; Bollini, Sveva; Vilahur, Gemma; Duncker, Dirk J.; Evans, Paul C.; Guzik, Tomasz; Hoefer, Imo E.; Waltenberger, Johannes; Wojta, Johann und Weber, Christian
(2021):
Progress in cardiac research: from rebooting cardiac regeneration to a complete cell atlas of the heart.
In: Cardiovascular Research, Bd. 117, Nr. 10: S. 2161-2174
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Dobersch, Stephanie; Rubio, Karla; Singh, Indrabahadur; Guenther, Stefan; Graumann, Johannes; Cordero, Julio; Castillo-Negrete, Rafael; Huynh, Minh Bao; Mehta, Aditi; Braubach, Peter; Cabrera-Fuentes, Hector; Bernhagen, Jürgen; Chao, Cho-Ming; Bellusci, Saverio; Guenther, Andreas; Preissner, Klaus T.; Kugel, Sita; Dobreva, Gergana; Wygrecka, Malgorzata; Braun, Thomas; Papy-Garcia, Dulce und Barreto, Guillermo
(2021):
Positioning of nucleosomes containing gamma-H2AX precedes active DNA demethylation and transcription initiation.
In: Nature Communications, Bd. 12, Nr. 1, 1072
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Dominko, Kristina; Rastija, Ana; Sobocanec, Sandra; Vidatic, Lea; Meglaj, Sarah; Lovincic Babic, Andrea; Hutter-Paier, Birgit; Colombo, Alessio-Vittorio; Lichtenthaler, Stefan F.; Tahirovic, Sabina und Hecimovic, Silva
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Impaired Retromer Function in Niemann-Pick Type C Disease Is Dependent on Intracellular Cholesterol Accumulation.
In: International Journal of Molecular Sciences, Bd. 22, Nr. 24, 13256
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Dordevic, Milos; Sulzer, Sabrina; Barche, Doreen; Dieterich, Marianne; Arens, Christoph und Mueller, Notger G.
(2021):
Chronic, Mild Vestibulopathy Leads to Deficits in Spatial Tasks that Rely on Vestibular Input While Leaving Other Cognitive Functions and Brain Volumes Intact.
In: Life-Basel, Bd. 11, Nr. 12, 1369
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Improving 3D convolutional neural network comprehensibility via interactive visualization of relevance maps: evaluation in Alzheimer's disease.
In: Alzheimer's Research & Therapy, Bd. 13, Nr. 1, 191
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Dzinovic, Ivana; Serranova, Tereza; Prouteau, Clement; Colin, Estelle; Ziegler, Alban; Winkelmann, Juliane; Jech, Robert und Zech, Michael
(2021):
Myoclonic dystonia phenotype related to a novel calmodulin-binding transcription activator 1 sequence variant.
In: Neurogenetics, Bd. 22, Nr. 2: S. 137-141
Dzinovic, Ivana; Skorvanek, Matej; Necpal, Jan; Boesch, Sylvia; Svantnerova, Jana; Wagner, Matias; Havrankova, Petra; Pavelekova, Petra; Han, Vladimir; Janzarik, Wibke G.; Berweck, Steffen; Diebold, Isabel; Kuster, Alice; Jech, Robert; Winkelmann, Juliane und Zech, Michael
(2021):
Dystonia as a prominent presenting feature in developmental and epileptic encephalopathies: A case series.
In: Parkinsonism & Related Disorders, Bd. 90: S. 73-78
Dzinovic, Ivana; Skorvanek, Matej; Pavelekova, Petra; Zhao, Chen; Keren, Boris; Whalen, Sandra; Bakhtiari, Somayeh; Chih Jin, Sheng; Kruer, Michael C.; Jech, Robert; Winkelmann, Juliane und Zech, Michael
(2021):
Variant recurrence confirms the existence of a FBXO31-related spastic-dystonic cerebral palsy syndrome.
In: Annals of Clinical and Translational Neurology, Bd. 8, Nr. 4: S. 951-955
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Egea, Virginia; Kessenbrock, Kai; Lawson, Devon; Bartelt, Alexander; Weber, Christian und Ries, Christian
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Let-7f miRNA regulates SDF-1α- and hypoxia-promoted migration of mesenchymal stem cells and attenuates mammary tumor growth upon exosomal release.
In: Cell death & disease, Bd. 12, Nr. 6, 516
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Egle, Marco; Hilal, Saima; Tuladhar, A. M.; Pirpamer, Lukas; Hofer, Edith; Duering, Marco; Wason, James; Morris, Robin G.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Schmidt, Reinhold; Tozer, Daniel; Chen, Christopher; De Leeuw, Frank-Erik und Markus, Hugh S.
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Prediction of dementia using diffusion tensor MRI measures: the OPTIMAL collaboration.
In: Journal of Neurology Neurosurgery and Psychiatry, Bd. 93, Nr. 1: S. 14-23
Eira, Jessica; Magalhaes, Joana; Macedo, Nidia; Pero, Maria Elena; Misgeld, Thomas; Sousa, Monica M.; Bartolini, Francesca und Liz, Marcia A.
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Transthyretin Promotes Axon Growth via Regulation of Microtubule Dynamics and Tubulin Acetylation.
In: Frontiers in Cell and Developmental Biology, Bd. 9, 747699
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Emes, David; Huls, Anke; Baumer, Nicole; Dierssen, Mara; Puri, Shiela; Russell, Lauren; Sherman, Stephanie L.; Strydom, Andre; Bargagna, Stefania; Brandao, Ana Claudia; Costa, Alberto C. S.; Feany, Patrick T.; Chicoine, Brian Allen; Ghosh, Sujay; Rebillat, Anne-Sophie; Sgandurra, Giuseppina; Valentini, Diletta; Rohrer, Tilman R.; Levin, Johannes und Lakhanpaul, Monica
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COVID-19 in Children with Down Syndrome: Data from the Trisomy 21 Research Society Survey.
In: Journal of Clinical Medicine, Bd. 10, Nr. 21, 5125
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Ende, Emma L. van der; Morenas-Rodriguez, Estrella; McMillan, Corey; Grossman, Murray; Irwin, David; Sanchez-Valle, Raquel; Graff, Caroline; Vandenberghe, Rik; Pijnenburg, Yolande A. L.; Laforce, Robert; Le Ber, Isabelle; Lleo, Alberto; Haass, Christian; Suarez-Calvet, Marc; Swieten, John C. van und Seelaar, Harro
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CSF sTREM2 is elevated in a subset in GRN-related frontotemporal dementia.
In: Neurobiology of Aging, Bd. 103
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Ende, Emma L.van der; Bron, Esther E.; Poos, Jackie M.; Jiskoot, Lize C.; Panman, Jessica L.; Papma, Janne M.; Meeter, Lieke H.; Dopper, Elise G. P.; Wilke, Carlo; Synofzik, Matthis; Heller, Carolin; Swift, Imogen J.; Sogorb-Esteve, Aitana; Bouzigues, Arabella; Borroni, Barbara; Sanchez-Valle, Raquel; Moreno, Fermin; Graff, Caroline; Laforce, Robert; Galimberti, Daniela; Masellis, Mario; Tartaglia, Maria Carmela; Finger, Elizabeth; Vandenberghe, Rik; Rowe, James B.; de Mendonca, Alexandre; Tagliavini, Fabrizio; Santana, Isabel; Ducharme, Simon; Butler, Christopher R.; Gerhard, Alexander; Levin, Johannes; Danek, Adrian; Otto, Markus; Pijnenburg, Yolande A. L.; Sorbi, Sandro; Zetterberg, Henrik; Niessen, Wiro J.; Rohrer, Jonathan D.; Klein, Stefan; Swieten, John C. van; Venkatraghavan, Vikram und Seelaar, Harro
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A data-driven disease progression model of fluid biomarkers in genetic frontotemporal dementia.
In: Brain, Bd. 145, Nr. 5: S. 1805-1817
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Engerer, Peter; Petridou, Eleni; Williams, Philip R.; Suzuki, Sachihiro C.; Yoshimatsu, Takeshi; Portugues, Ruben; Misgeld, Thomas und Godinho, Leanne
(2021):
Notch-mediated re-specification of neuronal identity during central nervous system development.
In: Current Biology, Bd. 31, Nr. 21: S. 4870-4878
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Escartin, Carole; Galea, Elena; Lakatos, Andras; O'Callaghan, James P.; Petzold, Gabor C.; Serrano-Pozo, Alberto; Steinhauser, Christian; Volterra, Andrea; Carmignoto, Giorgio; Agarwal, Amit; Allen, Nicola J.; Araque, Alfonso; Barbeito, Luis; Barzilai, Ari; Bergles, Dwight E.; Bonvento, Gilles; Butt, Arthur M.; Chen, Wei-Ting; Cohen-Salmon, Martine; Cunningham, Colm; Deneen, Benjamin; De Strooper, Bart; Diaz-Castro, Blanca; Farina, Cinthia; Freeman, Marc; Gallo, Vittorio; Goldman, James E.; Goldman, Steven A.; Gotz, Magdalena; Gutierrez, Antonia; Haydon, Philip G.; Heiland, Dieter H.; Hol, Elly M.; Holt, Matthew G.; Iino, Masamitsu; Kastanenka, Ksenia V.; Kettenmann, Helmut; Khakh, Baljit S.; Koizumi, Schuichi; Lee, C. Justin; Liddelow, Shane A.; MacVicar, Brian A.; Magistretti, Pierre; Messing, Albee; Mishra, Anusha; Molofsky, Anna V.; Murai, Keith K.; Norris, Christopher M.; Okada, Seiji; Oliet, Stephane H. R.; Oliveira, Joao F.; Panatier, Aude; Parpura, Vladimir; Pekna, Marcela; Pekny, Milos; Pellerin, Luc; Perea, Gertrudis; Perez-Nievas, Beatriz G.; Pfrieger, Frank W.; Poskanzer, Kira E.; Quintana, Francisco J.; Ransohoff, Richard M.; Riquelme-Perez, Miriam; Robel, Stefanie; Rose, Christine R.; Rothstein, Jeffrey D.; Rouach, Nathalie; Rowitch, David H.; Semyanov, Alexey; Sirko, Swetlana; Sontheimer, Harald; Swanson, Raymond A.; Vitorica, Javier; Wanner, Ina-Beate; Wood, Levi B.; Wu, Jiaqian; Zheng, Binhai; Zimmer, Eduardo R.; Zorec, Robert; Sofroniew, Michael V. und Verkhratsky, Alexei
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Reactive astrocyte nomenclature, definitions, and future directions.
In: Nature Neuroscience, Bd. 24, Nr. 3: S. 312-325
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Ewers, Michael; Luan, Ying; Frontzkowski, Lukas; Neitzel, Julia; Rubinski, Anna; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Hassenstab, Jason; Gordon, Brian A.; Chhatwal, Jasmeer P.; Levin, Johannes; Schofield, Peter; Benzinger, Tammie L. S.; Morris, John C.; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Allegri, Ricardo; Berman, Sarah; Chui, Helena; Cruchaga, Carlos; Farlow, Marty; Graff-Radford, Neill; Jucker, Mathias; Lee, Jae-Hong; Martins, Ralph N.; Mori, Hiroshi; Perrin, Richard; Xiong, Chengjie; Rossor, Martin; Fox, Nick C.; O'Connor, Antoinette; Salloway, Stephen; Danek, Adrian; Buerger, Katharina; Bateman, Randall J.; Habeck, Christian; Stern, Yaakov und Franzmeier, Nicolai
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Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease.
In: Brain, Bd. 144: S. 2176-2185
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Fauser, Mareike; Pan-Montojo, Francisco; Richter, Christian; Kahle, Philipp J.; Schwarz, Sigrid C.; Schwarz, Johannes; Storch, Alexander und Hermann, Andreas
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Chronic-Progressive Dopaminergic Deficiency Does Not Induce Midbrain Neurogenesis.
In: Cells, Bd. 10, Nr. 4, 775
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(2021):
Safety and Efficacy of Acetyl-DL-Leucine in Certain Types of Cerebellar Ataxia: The ALCAT Randomized Clinical Crossover Trial.
In: JAMA Network Open, Bd. 4, Nr. 12, e2135841
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Feil, Katharina; Herzberg, Moriz; Dorn, Franziska; Tiedt, Steffen; Kupper, Clemens; Thunstedt, Dennis C.; Papanagiotou, Panagiotis; Meyer, Lukas; Kastrup, Andreas; Dimitriadis, Konstantinos; Liebig, Thomas; Dieterich, Marianne und Kellert, Lars
(2021):
Tandem Lesions in Anterior Circulation Stroke Analysis of the German Stroke Registry-Endovascular Treatment.
In: Stroke, Bd. 52, Nr. 4: S. 1265-1275
Feil, Katharina; Herzberg, Moriz; Dorn, Franziska; Tiedt, Steffen; Küpper, Clemens; Goss, Sebastian; Liebig, Thomas; Dieterich, Marianne; Bayer, Andreas; Kellert, Lars; Thunstedt, Dennis C.; Hinske, Ludwig C. und Mühlbauer, Konstanze
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General Anesthesia versus Conscious Sedation in Mechanical Thrombectomy.
In: Journal of Stroke, Bd. 23, Nr. 1: S. 103-112
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Feil, Katharina; Kuepper, Clemens; Tiedt, Steffen; Dimitriadis, Konstantinos; Herzberg, Moriz; Dorn, Franziska; Liebig, Thomas; Dieterich, Marianne und Kellert, Lars
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Safety and efficacy of mechanical thrombectomy in infective endocarditis: A matched case–control analysis from the German Stroke Registry–Endovascular Treatment.
In: European Journal of Neurology, Bd. 28, Nr. 3: S. 861-867
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Inter-hospital transfer for mechanical thrombectomy within the supraregional stroke network NEVAS.
In: Journal of neurology, Bd. 268, Nr. 2: S. 623-631
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Findeiss, Elisabeth; Schwarz, Sigrid C.; Evsyukov, Valentin; Roesler, Thomas W.; Hoellerhage, Matthias; Chakroun, Tasnim; Nykaenen, Niko-Petteri; Shen, Yimin; Wurst, Wolfgang; Kohl, Michael; Tost, Joerg und Hoeglinger, Guenter U.
(2021):
Comprehensive miRNome-Wide Profiling in a Neuronal Cell Model of Synucleinopathy Implies Involvement of Cell Cycle Genes.
In: Frontiers in Cell and Developmental Biology, Bd. 9, 561086
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(2021):
Genome-wide association study of panic disorder reveals genetic overlap with neuroticism and depression.
In: Molecular Psychiatry, Bd. 26, Nr. 8: S. 4179-4190
Franklin, Hannah D.; Russell, Lucy L.; Peakman, Georgia; Greaves, Caroline V.; Bocchetta, Martina; Nicholas, Jennifer; Poos, Jackie; Convery, Rhian S.; Cash, David M.; Swieten, John van; Jiskoot, Lize; Moreno, Fermin; Sanchez-Valle, Raquel; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Maria Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B.; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; Mendonca, Alexandre de; Tagliavini, Fabrizio; Santana, Isabel; Ducharme, Simon; Butler, Chris; Gerhard, Alex; Levin, Johannes; Danek, Adrian; Otto, Markus; Sorbi, Sandro; Le Ber, Isabelle; Pasquier, Florence und Rohrer, Jonathan D.
(2021):
The Revised Self-Monitoring Scale detects early impairment of social cognition in genetic frontotemporal dementia within the GENFI cohort.
In: Alzheimer's Research & Therapy, Bd. 13, Nr. 1, 127
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Franzmeier, Nicolai; Ossenkoppele, Rik; Brendel, Matthias; Rubinski, Anna; Smith, Ruben; Kumar, Atul; Mattsson-Carlgren, Niklas; Strandberg, Olof; Duering, Marco; Buerger, Katharina; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Hansson, Oskar und Ewers, Michael
(2021):
The BIN1 rs744373 Alzheimer's disease risk SNP is associated with faster A beta-associated tau accumulation and cognitive decline.
In: Alzheimers & Dementia, Bd. 18, Nr. 1: S. 103-115
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Franzmeier, Nicolai; Ren, Jinyi; Damm, Alexander; Monte-Rubio, Gemma; Boada, Merce; Ruiz, Agustin; Ramirez, Alfredo; Jessen, Frank; Duezel, Emrah; Rodriguez Gomez, Octavio; Benzinger, Tammie; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Buerger, Katharina; Levin, Johannes; Duering, Marco; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Suarez-Calvet, Marc; Haass, Christian; Gordon, Brian A.; Lim, Yen Ying; Masters, Colin L.; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Milz, Esther; Moreno-Grau, Sonia; Teipel, Stefan; Grothe, Michel J.; Kilimann, Ingo; Rossor, Martin; Fox, Nick; Laske, Christoph; Chhatwal, Jasmeer; Falkai, Peter; Perneczky, Robert; Lee, Jae-Hong; Spottke, Annika; Boecker, Henning; Brosseron, Frederic; Fliessbach, Klaus; Heneka, Michael T.; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Araque Caballero, Miguel angel; Metzger, Coraline; Bittner, Daniel; Salloway, Stephen; Danek, Adrian; Hassenstab, Jason; Yakushev, Igor; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und Ewers, Michael
(2021):
The BDNFVal66Met SNP modulates the association between beta-amyloid and hippocampal disconnection in Alzheimer's disease.
In: Molecular Psychiatry, Bd. 26, Nr. 2: S. 614-628
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Galanis, Christos; Fellenz, Meike; Becker, Denise; Bold, Charlotte; Lichtenthaler, Stefan F.; Mueller, Ulrike C.; Deller, Thomas und Vlachos, Andreas
(2021):
Amyloid-Beta Mediates Homeostatic Synaptic Plasticity.
In: Journal of Neuroscience, Bd. 41, Nr. 24: S. 5157-5172
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Garvert, Linda; Baune, Bernhard T.; Berger, Klaus; Boomsma, Dorret; Breen, Gerome; Greinacher, Andreas; Hamilton, Steven P.; Levinson, Douglas F.; Lewis, Cathryn M.; Lucae, Susanne; Magnusson, Patrik K. E.; Martin, Nicholas G.; McIntosh, Andrew M.; Mors, Ole; Mueller-Myhsok, Bertram; Penninx, Brenda W. J. H.; Perlis, Roy H.; Pistis, Giorgio; Potash, James B.; Preisig, Martin; Rietschel, Marcella; Shi, Jianxin; Smoller, Jordan W.; Tiemeier, Henning; Uher, Rudolf; Voelker, Uwe; Voelzke, Henry; Weissman, Myrna M.; Grabe, Hans J. und Van der Auwera, Sandra
(2021):
The association between genetically determined ABO blood types and major depressive disorder.
In: Psychiatry Research, Bd. 299, 113837
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Gasperi, Christiane; Hapfelmeier, Alexander; Daltrozzo, Tanja; Schneider, Antonius; Donnachie, Ewan und Hemmer, Bernhard
(2021):
Systematic Assessment of Medical Diagnoses Preceding the First Diagnosis of Multiple Sclerosis.
In: Neurology, Bd. 96, Nr. 24, E2977-E2988
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Gencer, Selin; Doering, Yvonne; Jansen, Yvonne; Bayasgalan, Soyolmaa; Schengel, Olga; Mueller, Madeleine; Peters, Linsey J. F.; Weber, Christian und Vorst, Emiel P. C. van der
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Adipocyte-Specific ACKR3 Regulates Lipid Levels in Adipose Tissue.
In: Biomedicines, Bd. 9, Nr. 4, 394
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Gengatharan, Archana; Malvaut, Sarah; Marymonchyk, Alina; Ghareghani, Majid; Snapyan, Marina; Fischer-Sternjak, Judith; Ninkovic, Jovica; Gotz, Magdalena und Saghatelyan, Armen
(2021):
Adult neural stem cell activation in mice is regulated by the day/night cycle and intracellular calcium dynamics.
In: Cell, Bd. 184, Nr. 3: S. 709-722
Georgakis, Marios K.; Harshfield, Eric L.; Malik, Rainer; Franceschini, Nora; Langenberg, Claudia; Wareham, Nicholas J.; Markus, Hugh S. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2021):
Diabetes Mellitus, Glycemic Traits, and Cerebrovascular Disease A Mendelian Randomization Study.
In: Neurology, Bd. 96, Nr. 13, E1732-E1742
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Georgakis, Marios K.; Laan, Sander W. van der; Asare, Yaw; Mekke, Joost M.; Haitjema, Saskia; Schoneveld, Arjan H.; de Jager, Saskia C. A.; Nurmohamed, Nick S.; Kroon, Jeffrey; Stroes, Erik S. G.; Kleijn, Dominique P. V. de; Borst, Gert J. de; Maegdefessel, Lars; Soehnlein, Oliver; Pasterkamp, Gerard und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2021):
Monocyte-Chemoattractant Protein-1 Levels in Human Atherosclerotic Lesions Associate With Plaque Vulnerability.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 41, Nr. 6: S. 2038-2048
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(2021):
Genetically Downregulated Interleukin-6 Signaling Is Associated With a Favorable Cardiometabolic Profile A Phenome-Wide Association Study.
In: Circulation, Bd. 143, Nr. 11: S. 1177-1180
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Mendelian randomization for studying the effects of perturbing drug targets.
In: Wellcome Open Research, Bd. 6, 16
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Accelerated functional brain aging in pre-clinical familial Alzheimer's disease.
In: Nature Communications, Bd. 12, Nr. 1, 5346
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Gouna, Garyfallia; Klose, Christian; Bosch-Queralt, Mar; Liu, Lu; Gokce, Ozgun; Schifferer, Martina; Cantuti-Castelvetri, Ludovico und Simons, Mikael
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TREM2-dependent lipid droplet biogenesis in phagocytes is required for remyelination.
In: Journal of Experimental Medicine, Bd. 218, Nr. 10, e20210227
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Grahl, S.; Bussas, M.; Pongratz, V.; Kirschke, J. S.; Zimmer, C.; Berthele, A.; Hemmer, B. und Muehlau, M.
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T1-Weighted Intensity Increase After a Single Administration of a Linear Gadolinium-Based Contrast Agent in Multiple Sclerosis.
In: Clinical Neuroradiology, Bd. 31, Nr. 1: S. 235-243
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Differential Effects of Fingolimod and Natalizumab on Magnetic Resonance Imaging Measures in Relapsing-Remitting Multiple Sclerosis.
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Population impact of different hypertension management guidelines based on the prospective population-based Heinz Nixdorf Recall study.
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Metabolic connectivity-based single subject classification by multi-regional linear approximation in the rat.
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Dynamic whole-brain metabolic connectivity during vestibular compensation in the rat.
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(2021):
Obesity-associated hyperleptinemia alters the gliovascular interface of the hypothalamus to promote hypertension.
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Chemokine-like MDL proteins modulate flowering time and innate immunity in plants.
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Novel EDGE encoding method enhances ability to identify genetic interactions.
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Quality of Life in Advanced Dementia with Late Onset, Young Onset, and Very Young Onset.
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Identification of Hypoxia Induced Metabolism Associated Genes in Pulmonary Hypertension.
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Chronic T cell proliferation in brains after stroke could interfere with the efficacy of immunotherapies.
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Unexpected Pro-Fibrotic Effect of MIF in Non-Alcoholic Steatohepatitis Is Linked to a Shift in NKT Cell Populations.
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Held, Friederike; Kalluri, Sudhakar Reddy; Berthele, Achim; Klein, Ana-Katharina; Reindl, Markus und Hemmer, Bernhard
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Frequency of myelin oligodendrocyte glycoprotein antibodies in a large cohort of neurological patients.
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Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity.
In: Nature Immunology, Bd. 22, Nr. 7: S. 880-892
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Acute mental stress drives vascular inflammation and promotes plaque destabilization in mouse atherosclerosis.
In: European Heart Journal, Bd. 42, Nr. 39: S. 4077-4088
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The Role of Macrophage Migration Inhibitory Factor in Adipose-Derived Stem Cells Under Hypoxia.
In: Frontiers in Physiology, Bd. 12, 638448
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(2021):
Endoglycan (PODXL2) is proteolytically processed by ADAM10 (a disintegrin and metalloprotease 10) and controls neurite branching in primary neurons.
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A microRNA signature that correlates with cognition and is a target against cognitive decline.
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Macrophage migration inhibitory factor promotes the migration of dendritic cells through CD74 and the activation of the Src/PI3K/myosin II pathway.
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Phagocyte-mediated synapse removal in cortical neuroinflammation is promoted by local calcium accumulation.
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Longitudinal Accumulation of Cerebral Microhemorrhages in Dominantly Inherited Alzheimer Disease.
In: Neurology, Bd. 96, Nr. 12, E1632-E1645
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TREM2 modulates differential deposition of modified and non-modified A beta species in extracellular plaques and intraneuronal deposits.
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Differential interaction with TREM2 modulates microglial uptake of modified A beta species.
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(2021):
Ponesimod Compared With Teriflunomide in Patients With Relapsing Multiple Sclerosis in the Active-Comparator Phase 3 OPTIMUM Study A Randomized Clinical Trial.
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Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2.
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Multi-shell Diffusion MRI Models for White Matter Characterization in Cerebral Small Vessel Disease.
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Long-term dynamics of aberrant neuronal activity in awake Alzheimer's disease transgenic mice.
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Detection Gap of Right-Asymmetric Neuronal Degeneration by CERAD Test Battery in Alzheimer's Disease.
In: Frontiers in Aging Neuroscience, Bd. 13, 611595
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Keratinocyte-intrinsic BCL10/MALT1 activity initiates and amplifies psoriasiform skin inflammation.
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Cell-specific and divergent roles of the CD40L-CD40 axis in atherosclerotic vascular disease.
In: Nature Communications, Bd. 12, Nr. 1, 3754
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Congenital heart disease risk loci identified by genome-wide association study in European patients.
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Repetitive injury and absence of monocytes promote astrocyte self-renewal and neurological recovery.
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Ethical use of off-label disease-modifying therapies for multiple sclerosis.
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Phosphorylation Regulates CIRBP Arginine Methylation, Transportin-1 Binding and Liquid-Liquid Phase Separation.
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Prioritizing the Role of Major Lipoproteins and Subfractions as Risk Factors for Peripheral Artery Disease.
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A Randomized Controlled Trial Evaluating Integrative Psychotherapeutic Group Treatment Compared to Self-Help Groups in Functional Vertigo/Dizziness.
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Dissociation of microdissected mouse brain tissue for artifact free-cell RNA.
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Highly efficient intercellular spreading of protein misfolding mediated by viral ligand-receptor interactions.
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Circadian Biology and Stroke.
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Quantifying progression in primary progressive aphasia with structural neuroimaging.
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Kognition bei Down-Syndrom: Entwicklung über die Lebensspanne und neuropsychologische Diagnostik im Erwachsenenalter.
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Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
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Modeling autosomal dominant Alzheimer's disease with machine learning.
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Features of MOG required for recognition by patients with MOG antibody-associated disorders.
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TSPO PET imaging of natalizumab-associated progressive multifocal leukoencephalopathy.
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Whole-exome sequencing reveals a role of HTRA1 and EGFL8 in brain white matter hyperintensities.
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Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology.
In: Nature Genetics, Bd. 53, Nr. 6: S. 817-829
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KL-VS heterozygosity is associated with lower amyloid-dependent tau accumulation and memory impairment in Alzheimer's disease.
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Clinical, neuroimaging, and molecular spectrum of TECPR2-associated hereditary sensory and autonomic neuropathy with intellectual disability.
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Intravitreal Gene Therapy vs. Natural History in Patients With Leber Hereditary Optic Neuropathy Carrying the m.11778G>A ND4 Mutation: Systematic Review and Indirect Comparison.
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Efficacy and Safety of Intravitreal Gene Therapy for Leber Hereditary Optic Neuropathy Treated within 6 Months of Disease Onset.
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Mitochondrial disease in adults: recent advances and future promise.
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Galvanic Vestibular Stimulation Improves Spatial Cognition After Unilateral Labyrinthectomy in Mice.
In: Frontiers in Neurology, Bd. 12, 716795
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Nguyen, Thanh Tin; Nam, Gi-Sung; Kang, Jin-Ju; Han, Gyu Cheol; Kim, Ji-Soo; Dieterich, Marianne und Oh, Sun-Young
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The Differential Effects of Acute Right- vs. Left-Sided Vestibular Deafferentation on Spatial Cognition in Unilateral Labyrinthectomized Mice.
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Pro-inflammatory Monocyte Phenotype During Acute Progression of Cerebral Small Vessel Disease.
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Low-degree trisomy 21 mosaicism promotes early-onset Alzheimer disease.
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TRAF6 prevents fatal inflammation by homeostatic suppression of MALT1 protease.
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Endolymphatic Hydrops in Patients With Vestibular Migraine and Concurrent Meniere's Disease.
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The beta-Secretase Substrate Seizure 6-Like Protein (SEZ6L) Controls Motor Functions in Mice.
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Suicidal Ideations and Behavior in Patients With Young and Late Onset Dementia.
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Sunlight exposure exerts immunomodulatory effects to reduce multiple sclerosis severity.
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Recurrent VPS16 p.Arg187*Nonsense Variant in Early- Onset Generalized Dystonia.
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Cortical [F-18]PI-2620 Binding Differentiates Corticobasal Syndrome Subtypes.
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Atypical presentations of DYT1 dystonia with acute craniocervical onset.
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Comparison of clinical rating scales in genetic frontotemporal dementia within the GENFI cohort.
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Proteomic and lipidomic profiling of demyelinating lesions identifies fatty acids as modulators in lesion recovery.
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A Nation-Wide, Multi-Center Study on the Quality of Life of ALS Patients in Germany.
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(2021):
AMPK-regulated miRNA-210-3p is activated during ischaemic neuronal injury and modulates PI3K-p70S6K signalling.
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Impairment of episodic memory in genetic frontotemporal dementia: A GENFI study.
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Smoking and alcohol, health-related quality of life and psychiatric comorbidities in Leber's Hereditary Optic Neuropathy mutation carriers: a prospective cohort study.
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Resting-State Network Alterations Differ between Alzheimer's Disease Atrophy Subtypes.
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Binding of phosphatidylserine-positive microparticles by PSPRINGER NATURE classifies disease severity in COVID-19 patients.
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The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid-liquid phase separation.
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Progression characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS): a 4-year cohort study.
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Circadian rhythm of ischaemic core progression in human stroke.
In: Journal of Neurology, Neurosurgery & Psychiatry, Bd. 94, Nr. 1: S. 70-73
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Sulthiame impairs mitochondrial function in vitro and may trigger onset of visual loss in Leber hereditary optic neuropathy.
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Tissue clearing.
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In: Neuroimage-Clinical, Bd. 30, 102683
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Plasma Neurofilament Light for Prediction of Disease Progression in Familial Frontotemporal Lobar Degeneration.
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How Do Persons with Young and Late Onset Dementia Die?
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Post-injury immunosuppression and secondary infections are caused by an AIM2 inflammasome-driven signaling cascade.
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The Clinical and Neuropathological Features of Sporadic (Late-Onset) and Genetic Forms of Alzheimer's Disease.
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CRISPR-Mediated Induction of Neuron-Enriched Mitochondrial Proteins Boosts Direct Glia-to-Neuron Conversion.
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(2021):
ADAM10-Mediated Ectodomain Shedding Is an Essential Driver of Podocyte Damage.
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White matter aging drives microglial diversity.
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Approved drugs ezetimibe and disulfiram enhance mitochondrial Ca2+ uptake and suppress cardiac arrhythmogenesis.
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Plasma microRNA signature associated with retinopathy in patients with type 2 diabetes.
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Cytoplasmic FUS triggers early behavioral alterations linked to cortical neuronal hyperactivity and inhibitory synaptic defects.
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Mutations in HID1 Cause Syndromic Infantile Encephalopathy and Hypopituitarism.
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(22. März 2021):
Pathophysiological Changes in the Enteric Nervous System of Rotenone-Exposed Mice as Early Radiological Markers for Parkinson's Disease.
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Single-cell profiling of CNS border compartment leukocytes reveals that B cells and their progenitors reside in non-diseased meninges.
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Schindler, Lisa; Zwissler, Leon; Krammer, Christine; Hendgen-Cotta, Ulrike; Rassaf, Tienush; Hampton, Mark B.; Dickerhof, Nina und Bernhagen, Jürgen
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Macrophage migration inhibitory factor inhibits neutrophil apoptosis by inducing cytokine release from mononuclear cells.
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(2021):
Informal Caregiving in Amyotrophic Lateral Sclerosis (ALS): A High Caregiver Burden and Drastic Consequences on Caregivers' Lives.
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Meta-analyses identify DNA methylation associated with kidney function and damage.
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(13. Mai 2021):
Dual-Phase β-Amyloid PET Captures Neuronal Injury and Amyloidosis in Corticobasal Syndrome.
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Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores.
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The Uppsala APP deletion causes early onset autosomal dominant Alzheimer's disease by altering APP processing and increasing amyloid β fibril formation.
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Knocking out C9ORF72 Exacerbates Axonal Trafficking Defects Associated with Hexanucleotide Repeat Expansion and Reduces Levels of Heat Shock Proteins.
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Modern machine-learning can support diagnostic differentiation of central and peripheral acute vestibular disorders.
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Analysis of brain atrophy and local gene expression in genetic frontotemporal dementia.
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Inner retinal layer thinning in radiologically isolated syndrome predicts conversion to multiple sclerosis.
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Treatment- and population-specific genetic risk factors for anti-drug antibodies against interferon-beta: a GWAS.
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Age‐dependent amyloid deposition is associated with white matter alterations in cognitively normal adults during the adult life span.
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Common Genetic Variation Indicates Separate Causes for Periventricular and Deep White Matter Hyperintensities.
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Aggressive multiple sclerosis (2): Treatment.
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Histone Deacetylase 9 Activates IKK to Regulate Atherosclerotic Plaque Vulnerability.
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Differential Role for Activating Fc gamma RIII in Neointima Formation After Arterial Injury and Diet-Induced Chronic Atherosclerosis inApolipoprotein E-Deficient Mice.
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Functional characterization of the first missense variant in CEP78, a founder allele associated with cone-rod dystrophy, hearing loss, and reduced male fertility.
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(2020):
TheMacrophage Migration Inhibitory Factor(MIF) Promoter Polymorphisms (rs3063368, rs755622) Predict Acute Kidney Injury and Death after Cardiac Surgery.
In: Journal of Clinical Medicine, Bd. 9, Nr. 9, 2936
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Proteome profiling in cerebrospinal fluid reveals novel biomarkers of Alzheimer's disease.
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Genome-wide association study of intracranial aneurysms identifies 17 risk loci and genetic overlap with clinical risk factors.
In: Nature Genetics, Bd. 52, Nr. 12: S. 1303-1313
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A soluble phosphorylated tau signature links tau, amyloid and the evolution of stages of dominantly inherited Alzheimer's disease.
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Barykina, Natalia V.; Sotskov, Vladimir P.; Gruzdeva, Anna M.; Wu, You Kure; Portugues, Ruben; Subach, Oksana M.; Chefanova, Elizaveta S.; Plusnin, Viktor V.; Ivashkina, Olga I.; Anokhin, Konstantin V.; Vlaskina, Anna V.; Korzhenevskiy, Dmitry A.; Nikolaeva, Alena Y.; Boyko, Konstantin M.; Rakitina, Tatiana V.; Varizhuk, Anna M.; Pozmogova, Galina E. und Subach, Fedor V.
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FGCaMP7, an Improved Version of Fungi-Based Ratiometric Calcium Indicator for In Vivo Visualization of Neuronal Activity.
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Regulatory myeloid cells paralyze T cells through cell-cell transfer of the metabolite methylglyoxal.
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Archeological neuroimmunology: resurrection of a pathogenic immune response from a historical case sheds light on human autoimmune encephalomyelitis and multiple sclerosis.
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Vitamin D, smoking, EBV, and long-term cognitive performance in MS 11-year follow-up of BENEFIT.
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Cserép, C.; Pósfai, B.; Lénárt, N.; Fekete, R.; László, Z. I.; Lele, Z.; Orsolits, B.; Molnár, G.; Heindl, S.; Schwarcz, A. D.; Ujvári, K.; Környei, Z.; Tóth, K.; Szabadits, E.; Sperlágh, B.; Baranyi, M.; Csiba, L.; Hortobágyi, T.; Maglóczky, Z.; Martinecz, B.; Szabó, G.; Erdélyi, F.; Szipőcs, R.; Tamkun, M. M.; Gesierich, B.; Duering, M.; Katona, I.; Liesz, Arthur; Tamás, G. und Dénes, Á.
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Microglia monitor and protect neuronal function through specialized somatic purinergic junctions.
In: Science, Bd. 367, Nr. 6477: S. 528-537
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Pro-inflammatory activation following demyelination is required for myelin clearance and oligodendrogenesis.
In: Journal of Experimental Medicine, Bd. 217, Nr. 5, e20191390
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Cystatin B is essential for proliferation and interneuron migration in individuals with EPM1 epilepsy.
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Protective effects of 4-aminopyridine in experimental optic neuritis and multiple sclerosis.
In: Brain, Bd. 143: S. 1127-1142
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Dincer, Aylin; Gordon, Brian A.; Hari-Raj, Amrita; Keefe, Sarah J.; Flores, Shaney; McKay, Nicole S.; Paulick, Angela M.; Lewis, Kristine E. Shady; Feldman, Rebecca L.; Hornbeck, Russ C.; Allegri, Ricardo; Ances, Beau M.; Berman, Sarah B.; Brickman, Adam M.; Brooks, William S.; Cash, David M.; Chhatwal, Jasmeer P.; Farlow, Martin R.; La Fougere, Christian; Fox, Nick C.; Fulham, Michael J.; Jack, Clifford R.; Joseph-Mathurin, Nelly; Karch, Celeste M.; Lee, Athene; Levin, Johannes; Masters, Colin L.; McDade, Eric M.; Oh, Hwamee; Perrin, Richard J.; Raji, Cyrus; Salloway, Stephen P.; Schofield, Peter R.; Su, Yi; Villemagne, Victor L.; Wang, Qing; Weiner, Michael W.; Xiong, Chengjie; Yakushev, Igor; Morris, John C.; Bateman, Randall J. und Benzinger, Tammie L. S.
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Comparing cortical signatures of atrophy between late-onset and autosomal dominant Alzheimer disease.
In: Neuroimage-Clinical, Bd. 28, 102491
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(2020):
Brain Iron and Metabolic Abnormalities in C19orf12 Mutation Carriers: A 7.0 Tesla MRI Study in Mitochondrial Membrane Protein–Associated Neurodegeneration.
In: Movement Disorders, Bd. 35, Nr. 1: S. 142-150
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(2020):
B-Cell–Specific CXCR4 Protects Against Atherosclerosis Development and Increases Plasma IgM Levels.
In: Circulation Research, Bd. 126, Nr. 6: S. 787-788
Eck, Franziska; Phuyal, Santosh; Smith, Matthew D.; Kaulich, Manuel; Wilkinson, Simon; Farhan, Hesso und Behrends, Christian
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ACSL3 is a novel GABARAPL2 interactor that links ufmylation and lipid droplet biogenesis.
In: Journal of Cell Science, Bd. 133, Nr. 18, jcs243477
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Chemokines and galectins form heterodimers to modulate inflammation.
In: Embo Reports, e47852
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Longitudinal TSPO expression in tau transgenic P301S mice predicts increased tau accumulation and deteriorated spatial learning.
In: Journal of Neuroinflammation, Bd. 17, Nr. 1, 208
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Ende, Emma L. van der; Xiao, Meifang; Xu, Desheng; Poos, Jackie M.; Panman, Jessica L.; Jiskoot, Lize C.; Meeter, Lieke H.; Dopper, Elise G. P.; Papma, Janne M.; Heller, Carolin; Convery, Rhian; Moore, Katrina; Bocchetta, Martina; Neason, Mollie; Peakman, Georgia; Cash, David M.; Teunissen, Charlotte E.; Graff, Caroline; Synofzik, Matthis; Moreno, Fermin; Finger, Elizabeth; Sanchez-Valle, Raquel; Vandenberghe, Rik; Laforce, Robert; Masellis, Mario; Tartaglia, Maria Carmela; Rowe, James B.; Butler, Christopher R.; Ducharme, Simon; Gerhard, Alex; Danek, Adrian; Levin, Johannes; Pijnenburg, Yolande A. L.; Otto, Markus; Borroni, Barbara; Tagliavini, Fabrizio; de Mendonca, Alexandre; Santana, Isabel; Galimberti, Daniela; Seelaar, Harro; Rohrer, Jonathan D.; Worley, Paul F. und Swieten, John C. van
(2020):
Neuronal pentraxin 2: a synapse-derived CSF biomarker in genetic frontotemporal dementia.
In: Journal of Neurology Neurosurgery and Psychiatry, Bd. 91, Nr. 6: S. 612-621
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Cognitive impairment in early MS: contribution of white matter lesions, deep grey matter atrophy, and cortical atrophy.
In: Journal of Neurology, Bd. 267, Nr. 8: S. 2307-2318
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Trnp1 organizes diverse nuclear membrane‐less compartments in neural stem cells.
In: EMBO, Bd. 39, Nr. 16, e103373
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(2020):
Endothelial dysfunction in COVID-19: a position paper of the ESC Working Group for Atherosclerosis and Vascular Biology, and the ESC Council of Basic Cardiovascular Science.
In: Cardiovascular Research, Bd. 116, Nr. 14: S. 2177-2184
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Higher CSF sTREM2 and microglia activation are associated with slower rates of beta-amyloid accumulation.
In: EMBO, Bd. 12, Nr. 9, e12308
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(2020):
Association between altered hippocampal oligodendrocyte number and neuronal circuit structures in schizophrenia: a postmortem analysis.
In: European Archives of Psychiatry and Clinical Neuroscience, Bd. 270, Nr. 4: S. 413-424
Fang, Renpeng; Haxaire, Coline; Otero, Miguel; Lessard, Samantha; Weskamp, Gisela; McIlwain, David R.; Mak, Tak W.; Lichtenthaler, Stefan E. und Blobel, Carl P.
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Role of iRhoms 1 and 2 in Endochondral Ossification.
In: International Journal of Molecular Sciences, Bd. 21, Nr. 22, 8732
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(2020):
What Is the Best Mix of Population-Wide and High-Risk Targeted Strategies of Primary Stroke and Cardiovascular Disease Prevention?
In: Journal of the American Heart Association, Bd. 9, Nr. 3, e014494
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The global burden of neurological disorders: translating evidence into policy.
In: Lancet Neurology, Bd. 19, Nr. 3: S. 255-265
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(2020):
Drip and ship for mechanical thrombectomy within the Neurovascular Network of Southwest Bavaria.
In: Neurology, Bd. 94, Nr. 5, E453-E463
Ferreiro, Dardo N.; Amaro, Diana; Schmidtke, Daniel; Sobolev, Andrey; Gundi, Paula T.; Belliveau, Lucile; Sirota, Anton ORCID: https://orcid.org/0000-0002-4700-6587; Grothe, Benedikt ORCID: https://orcid.org/0000-0001-7317-0615 und Pecka, Michael ORCID: https://orcid.org/0000-0001-8960-1651
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Sensory Island Task (SIT): A New Behavioral Paradigm to Study Sensory Perception and Neural Processing in Freely Moving Animals.
In: Frontiers in Behavioral Neuroscience, Bd. 14, 576154: S. 1-16
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Finsterwalder, Sofia; Vlegels, Naomi; Gesierich, Benno; Caballero, Miguel A. Araque; Weaver, Nick A.; Franzmeier, Nicolai; Georgakis, Marios K.; Konieczny, Marek J.; Koek, Huiberdina L.; Karch, Celeste M.; Graff-Radford, Neill R.; Salloway, Stephen; Oh, Hwamee; Allegri, Ricardo F.; Chhatwal, Jasmeer P.; Jessen, Frank; Duezel, Emrah; Dobisch, Laura; Metzger, Coraline; Peters, Oliver; Incesoy, Enise I.; Priller, Josef; Spruth, Eike J.; Schneider, Anja; Fliessbach, Klaus; Buerger, Katharina; Janowitz, Daniel; Teipel, Stefan J.; Kilimann, Ingo; Laske, Christoph; Buchmann, Martina; Heneka, Michael T.; Brosseron, Frederic; Spottke, Annika; Roy, Nina; Ertl-Wagner, Birgit; Scheffler, Klaus; Seo, Sang Won; Kim, Yeshin; Na, Duk L.; Kim, Hee Jin; Jang, Hyemin; Ewers, Michael; Levin, Johannes; Schmidt, Reinhold; Pasternak, Ofer; Dichgans, Martin; Biessels, Geert Jan und Duering, Marco
(2020):
Small vessel disease more than Alzheimer's disease determines diffusion MRI alterations in memory clinic patients.
In: Alzheimer's and Dementia, Bd. 16, Nr. 11: S. 1504-1514
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Fitzner, Dirk; Bader, Jakob M.; Penkert, Horst; Bergner, Caroline G.; Su, Minhui; Weil, Marie-Theres; Surma, Michal A.; Mann, Matthias; Klose, Christian und Simons, Mikael
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Cell-Type- and Brain-Region-Resolved Mouse Brain Lipidome.
In: Cell Reports, Bd. 32, Nr. 11, 108132
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Lysosomal targeting of autophagosomes by the TECPR domain of TECPR2.
In: Autophagy
Franzmeier, Nicolai; Dewenter, Anna; Frontzkowski, Lukas; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Rubinski, Anna; Neitzel, Julia; Smith, Ruben; Strandberg, Olof; Ossenkoppele, Rik; Buerger, Katharina; Duering, Marco; Hansson, Oskar und Ewers, Michael
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Patient-centered connectivity-based prediction of tau pathology spread in Alzheimer's disease.
In: Science Advances, Bd. 6, Nr. 48, abd1327
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Franzmeier, Nicolai; Koutsouleris, Nikolaos; Benzinger, Tammie; Goate, Alison; Karch, Celeste M.; Fagan, Anne M.; McDade, Eric; Duering, Marco; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Levin, Johannes; Gordon, Brian A.; Lim, Yen Ying; Masters, Colin L.; Rossor, Martin; Fox, Nick C.; O'Connor, Antoinette; Chhatwal, Jasmeer; Salloway, Stephen; Danek, Adrian; Hassenstab, Jason; Schofield, Peter R.; Morris, John C.; Bateman, Randall J. und Ewers, Michael
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Predicting sporadic Alzheimer's disease progression via inherited Alzheimer's disease-informed machine-learning.
In: Alzheimer's and Dementia, Bd. 16, Nr. 3: S. 501-511
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Franzmeier, Nicolai; Suarez-Calvet, M.; Frontzkowski, Lukas; Moore, Annah; Hohman, Timothy J.; Morenas-Rodriguez, Estrella; Nuscher, Brigitte; Shaw, Leslie; Trojanowski, John Q.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Kleinberger, Gernot; Haass, Christian und Ewers, Michael
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Higher CSF sTREM2 attenuates ApoE4-related risk for cognitive decline and neurodegeneration.
In: Molecular Neurodegeneration, Bd. 15, Nr. 1, 57
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Frederiksen, Kristian S.; Nielsen, Thomas R.; Appollonio, Ildebrando; Andersen, Birgitte Bo; Riverol, Mario; Boada, Merce; Ceccaldi, Mathieu; Dubois, Bruno; Engelborghs, Sebastiaan; Froelich, Lutz; Hausner, Lucrezia; Gabelle, Audrey; Gabryelewicz, Tomasz; Grimmer, Timo; Hanseeuw, Bernard; Hort, Jakub; Hugon, Jacques; Jelic, Vesna; Koivisto, Anne; Kramberger, Milica G.; Lebouvier, Thibaud; Lleo, Alberto; de Mendonca, Alexandre; Nobili, Flavio; Ousset, Pierre-Jean; Perneczky, Robert; Olde Rikkert, Marcel; Robinson, David; Rouaud, Olivier; Sanchez, Elisabet; Santana, Isabel; Scarmeas, Nikolaos; Sheardova, Katerina; Sloan, Stephanie; Spiru, Luiza; Stefanova, Elka; Traykov, Latchezar; Yener, Gorsev und Waldemar, Gunhild
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Biomarker counseling, disclosure of diagnosis and follow-up in patients with mild cognitive impairment: A European Alzheimer's disease consortium survey.
In: International Journal of Geriatric Psychiatry, Bd. 36, Nr. 2: S. 324-333
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Impact of Collateral Filling Delay on the Development of Subacute Complications After Acute Ischemic Stroke.
In: Clinical Neuroradiology, Bd. 30, Nr. 2: S. 331-337
Garcia-Cortadella, Ramon; Schäfer, Nathan; Cisneros-Fernandez, Jose; Ré, Lucia; Illa, Xavi; Schwesig, Gerrit; Moya, Ana; Santiago, Sara; Guirado, Gonzalo; Villa, Rosa; Sirota, Anton ORCID: https://orcid.org/0000-0002-4700-6587; Serra-Graells, Francesc; Garrido, Jose A. und Guimerà-Brunet, Anton
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Switchless Multiplexing of Graphene Active Sensor Arrays for Brain Mapping.
In: Nano Letters, Bd. 20, Nr. 5: S. 3528-3537
Garcia‐Cortadella, Ramon; Masvidal‐Codina, Eduard; De la Cruz, Jose M.; Schäfer, Nathan; Schwesig, Gerrit; Jeschke, Christoph; Martinez‐Aguilar, Javier; Sanchez‐Vives, Maria V.; Villa, Rosa; Illa, Xavi; Sirota, Anton ORCID: https://orcid.org/0000-0002-4700-6587; Guimerà, Anton und Garrido, Jose A.
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Distortion‐Free Sensing of Neural Activity Using Graphene Transistors.
In: Small, Bd. 16, Nr. 16, 1906640
Garrett, Lillian; Chang, Yoon Jeung; Niedermeier, Kristina M.; Heermann, Tamara; Enard, Wolfgang; Fuchs, Helmut; Gailus-Durner, Valerie; Hrabe de Angelis, Martin; Huttner, Wieland B.; Wurst, Wolfgang und Hoelter, Sabine M.
(2020):
A truncating Aspm allele leads to a complex cognitive phenotype and region-specific reductions in parvalbuminergic neurons.
In: Translational Psychiatry, Bd. 10, Nr. 1, 66
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Gasperi, Christiane; Andlauer, Till F. M.; Keating, Ana; Knier, Benjamin; Klein, Ana; Pernpeintner, Verena; Lichtner, Peter; Gold, Ralf; Zipp, Frauke; Bergh, Florian Then; Stangel, Martin; Tumani, Hayrettin; Wildemann, Brigitte; Wiendl, Heinz; Bayas, Antonios; Kuempfel, Tania; Zettl, Uwe K.; Linker, Ralf A.; Ziemann, Ulf; Knop, Matthias; Warnke, Clemens; Friese, Manuel A.; Paul, Friedemann; Tackenberg, Björn; Berthele, Achim und Hemmer, Bernhard
(2020):
Genetic determinants of the humoral immune response in MS.
In: Neurology-Neuroimmunology & Neuroinflammation, Bd. 7, Nr. 5, e827
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Gencer, Selin; Lacy, Michael; Atzler, Dorothee; Vorst, Emiel P. C. van der; Döring, Yvonne und Weber, Christian
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Immunoinflammatory, Thrombohaemostatic, and Cardiovascular Mechanisms in COVID-19.
In: Thrombosis and Haemostasis, Bd. 120, Nr. 12: S. 1629-1641
Georgakis, Marios K.; Gill, Dipender; Webb, Alastair J. S.; Evangelou, Evangelos; Elliott, Paul; Sudlow, Cathie L. M.; Dehghan, Abbas; Malik, Rainer; Tzoulaki, Ioanna und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
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Genetically determined blood pressure, antihypertensive drug classes, and risk of stroke subtypes.
In: Neurology, Bd. 95, Nr. 4, E353-E361
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Georgakis, Marios K.; de Lemos, James A.; Ayers, Colby; Wang, Biqi; Bjorkbacka, Harry; Pana, Tiberiu A.; Thorand, Barbara; Sun, Caroline; Fani, Lana; Malik, Rainer; Dupuis, Josee; Engstrom, Gunnar; Orho-Melander, Marju; Melander, Olle; Boekholdt, S. Matthijs; Zierer, Astrid; Elhadad, Mohamed A.; König, Wolfgang; Herder, Christian; Hoogeveen, Ron C.; Kavousi, Maryam; Ballantyne, Christie M.; Peters, Annette ORCID: https://orcid.org/0000-0001-6645-0985; Myint, Phyo K.; Nilsson, Jan; Benjamin, Emelia J. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2020):
Association of Circulating Monocyte Chemoattractant Protein-1 Levels With Cardiovascular Mortality A Meta-analysis of Population-Based Studies.
In: Jama Cardiology, Bd. 6, Nr. 5: S. 587-592
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Gerdes, Lisa Ann; Janoschka, Claudia; Eveslage, Maria; Mannig, Bianca; Wirth, Timo; Schulte-Mecklenbeck, Andreas; Lauks, Sarah; Glau, Laura; Gross, Catharina C.; Tolosa, Eva; Flierl-Hecht, Andrea; Ertl-Wagner, Birgit; Barkhof, Frederik; Meuth, Sven G.; Kuempfel, Tania; Wiendl, Heinz; Hohlfeld, Reinhard und Klotz, Luisa
(2020):
Immune signatures of prodromal multiple sclerosis in monozygotic twins.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 117, Nr. 35: S. 21546-21556
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Gerhards, Ramona; Pfeffer, Lena Kristina; Lorenz, Jessica; Starost, Laura; Nowack, Luise; Thaler, Franziska S.; Schlueter, Miriam; Ruebsamen, Heike; Macrini, Caterina; Winklmeier, Stephan; Mader, Simone; Bronge, Mattias; Groenlund, Hans; Feederle, Regina; Hsia, Hung-En; Lichtenthaler, Stefan F.; Merl-Pham, Juliane; Hauck, Stefanie M.; Kuhlmann, Tanja; Bauer, Isabel J.; Beltran, Eduardo; Gerdes, Lisa Ann; Mezydlo, Aleksandra; Bar-Or, Amit; Banwell, Brenda; Khademi, Mohsen; Olsson, Tomas; Hohlfeld, Reinhard; Lassmann, Hans; Kuempfel, Tania; Kawakami, Naoto und Meinl, Edgar
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Oligodendrocyte myelin glycoprotein as a novel target for pathogenic autoimmunity in the CNS.
In: Acta Neuropathologica Communications, Bd. 8, Nr. 1, 207
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Gesierich, Benno; Tuladhar, Anil Man; ter Telgte, Annemieke; Wiegertjes, Kim; Konieczny, Marek J.; Finsterwalder, Sofia; Huebner, Mathias; Pirpamer, Lukas; Koini, Marisa; Abdulkadir, Ahmed; Franzmeier, Nicolai; Norris, David G.; Marques, Jose P.; zu Eulenburg, Peter; Ewers, Michael; Schmidt, Reinhold; de Leeuw, Frank-Erik und Duering, Marco
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Alterations and test-retest reliability of functional connectivity network measures in cerebral small vessel disease.
In: Human Brain Mapping, Bd. 41, Nr. 10: S. 2629-2641
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Genome-wide association study reveals new insights into the heritability and genetic correlates of developmental dyslexia.
In: Molecular psychiatry
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Gill, Dipender; Georgakis, Marios K.; Zuber, Verena; Karhunen, Ville; Burgess, Stephen; Malik, Rainer und Dichgans, Martin
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Genetically Predicted Midlife Blood Pressure and Coronary Artery Disease Risk: Mendelian Randomization Analysis.
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(2020):
Classical Human Leukocyte Antigen Alleles and C4 Haplotypes Are Not Significantly Associated With Depression.
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Granier, Charlene; Schwarting, Julian; Fourli, Evangelia; Laage-Gaupp, Fabian; Hennrich, Alexandru A.; Schmalz, Anja; Jacobi, Anne; Wesolowski, Marta; Conzelmann, Karl-Klaus und Bareyre, Florence M.
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The genetic architecture of the human cerebral cortex.
In: Science, Bd. 367, Nr. 6484, eaay6690:
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A genome-wide cross-phenotype meta-analysis of the association of blood pressure with migraine.
In: Nature Communications, Bd. 11, 3368
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(2020):
Genetic comorbidity between major depression and cardio‐metabolic traits, stratified by age at onset of major depression.
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Hamid, Syed Muhammad; Citir, Mevlut; Terzi, Erdem Murat; Cimen, Ismail; Yildirim, Zehra; Dogan, Asli Ekin; Kocaturk, Begum; Onat, Umut Inci; Arditi, Moshe; Weber, Christian; Traynor-Kaplan, Alexis; Schultz, Carsten und Erbay, Ebru
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Inositol-requiring enzyme-1 regulates phosphoinositide signaling lipids and macrophage growth.
In: EMBO Reports, Bd. 21, Nr. 12, e51462
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Hassler, Signe; Bachelet, Delphine; Duhaze, Julianne; Szely, Natacha; Gleizes, Aude; Abina, Salima Hacein-Bey; Aktas, Orhan; Auer, Michael; Avouac, Jerome; Birchler, Mary; Bouhnik, Yoram; Brocq, Olivier; Buck-Martin, Dorothea; Cadiot, Guillaume; Carbonnel, Franck; Chowers, Yehuda; Comabella, Manuel; Derfuss, Tobias; De Vries, Niek; Donnellan, Naoimh; Doukani, Abiba; Guger, Michael; Hartung, Hans-Peter; Havrdova, Eva Kubala; Hemmer, Bernhard; Huizinga, Tom; Ingenhoven, Kathleen; Hyldgaard-Jensen, Poul Erik; Jury, Elizabeth C.; Khalil, Michael; Kieseier, Bernd; Lauren, Anna; Lindberg, Raija; Loercher, Amy; Maggi, Enrico; Manson, Jessica; Mauri, Claudia; Oumoussa, Badreddine Mohand; Montalban, Xavier; Nachury, Maria; Nytrova, Petra; Richez, Christophe; Ryner, Malin; Sellebjerg, Finn; Sievers, Claudia; Sikkema, Dan; Soubrier, Martin; Tourdot, Sophie; Trang, Caroline; Vultaggio, Alessandra; Warnke, Clemens; Spindeldreher, Sebastian; Donnes, Pierre; Hickling, Timothy P.; Mery, Agnes Hincelin; Allez, Matthieu; Deisenhammer, Florian; Fogdell-Hahn, Anna; Mariette, Xavier; Pallardy, Marc und Broet, Philippe
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Clinicogenomic factors of biotherapy immunogenicity in autoimmune disease: A prospective multicohort study of the ABIRISK consortium.
In: PLOS Medicine
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(2020):
Longitudinal prevalence and determinants of pain in multiple sclerosis: results from the German National Multiple Sclerosis Cohort study.
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Heller, Carolin; Foiani, Martha S.; Moore, Katrina; Convery, Rhian; Bocchetta, Martina; Neason, Mollie; Cash, David M.; Thomas, David; Greaves, Caroline V.; Woollacott, Ione O. C.; Shafei, Rachelle; Swieten, John C. van; Moreno, Fermin; Sanchez-Valle, Raquel; Borroni, Barbara; Laforce, Robert; Masellis, Mario; Tartaglia, Maria Carmela; Graff, Caroline; Galimberti, Daniela; Rowe, James B.; Finger, Elizabeth; Synofzik, Matthis; Vandenberghe, Rik; de Mendonca, Alexandre; Tagliavini, Fabrizio; Santana, Isabel; Ducharme, Simon; Butler, Christopher R.; Gerhard, Alex; Levin, Johannes; Danek, Adrian; Frisoni, Giovanni; Sorbi, Sandro; Otto, Markus; Heslegrave, Amanda J.; Zetterberg, Henrik und Rohrer, Jonathan D.
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Plasma glial fibrillary acidic protein is raised in progranulin-associated frontotemporal dementia.
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BAG3 Proteomic Signature under Proteostasis Stress.
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Hoffmann, Adrian; Zwißler, Leon Christian; El Bounkari, Omar und Bernhagen, Jürgen
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Studying the Pro-Migratory Effects of MIF.
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(2020):
beta-adrenoreceptors and the risk of Parkinson's disease.
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Private variants in PRKN are associated with late-onset Parkinson's disease.
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Rare Variants in Specific Lysosomal Genes Are Associated With Parkinson's Disease.
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Bi-allelic HPDL Variants Cause a Neurodegenerative Disease Ranging from Neonatal Encephalopathy to Adolescent-Onset Spastic Paraplegia.
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Neural Correlates of Transient Mal de Debarquement Syndrome: Activation of Prefrontal and Deactivation of Cerebellar Networks Correlate With Neuropsychological Assessment.
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AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.
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Genome-Wide Association Study Meta-Analysis of Stroke in 22 000 Individuals of African Descent Identifies Novel Associations With Stroke.
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Defining the Adult Neural Stem Cell Niche Proteome Identifies Key Regulators of Adult Neurogenesis.
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Fosmetpantotenate Randomized Controlled Trial in Pantothenate Kinase-Associated Neurodegeneration.
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A comprehensive and comparative phenotypic analysis of the collaborative founder strains identifies new and known phenotypes.
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Designed CXCR4 mimic acts as a soluble chemokine receptor that blocks atherogenic inflammation by agonist-specific targeting.
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The tetraspanin Tspan15 is an essential subunit of an ADAM10 scissor complex.
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Complicated Carotid Artery Plaques as a Cause of Cryptogenic Stroke.
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A MIF-Derived Cyclopeptide that Inhibits MIF Binding and Atherogenic Signaling via the Chemokine Receptor CXCR2.
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In vivo identification of apoptotic and extracellular vesicle-bound live cells using image-based deep learning.
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Basic Fibroblast Growth Factor 2-Induced Proteome Changes Endorse Lewy Body Pathology in Hippocampal Neurons.
In: Iscience, Bd. 23, Nr. 8, 101349
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Fibroblast Growth Factor 2-Mediated Regulation of Neuronal Exosome Release Depends on VAMP3/Cellubrevin in Hippocampal Neurons.
In: Advanced Science, Bd. 7, Nr. 6, 1902372
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Endovascular stroke treatment in orally anticoagulated patients: an analysis from the German Stroke Registry-Endovascular Treatment.
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Congenic expression of poly-GA but not poly-PR in mice triggers selective neuron loss and interferon responses found in C9orf72 ALS.
In: Acta Neuropathologica, Bd. 140, Nr. 2: S. 121-142
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Reduced mitochondrial resilience enables non-canonical induction of apoptosis after TNF receptor signaling in virus-infected hepatocytes.
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Variability of clinical syndromes and cerebral glucose metabolism in symptomatic frontotemporal lobar degeneration associated with progranulin mutations.
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The Deep Genome Project.
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In-depth phenotyping reveals common and novel disease symptoms in a hemizygous knock-in mouse model (Mut-ko/ki) of mut-type methylmalonic aciduria.
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The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons.
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A Mendelian randomization of gamma ' and total fibrinogen levels in relation to venous thromboembolism and ischemic stroke.
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Progressive Histopathological Damage Occurring Up to One Year after Experimental Traumatic Brain Injury Is Associated with Cognitive Decline and Depression-Like Behavior.
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Mendelian Randomization Study of Obesity and Cerebrovascular Disease.
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A phenome-wide association and Mendelian Randomisation study of polygenic risk for depression in UK Biobank.
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Myelin replacement triggered by single-cell demyelination in mouse cortex.
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2019
Abdelhak, Ahmed; Hottenrott, Tilman; Morenas-Rodriguez, Estrella; Suarez-Calvet, Marc; Zettl, Uwe K.; Haass, Christian; Meuth, Sven G.; Rauer, Sebastian; Otto, Markus; Tumani, Hayrettin und Huss, Andre
(März 2019):
Glial Activation Markers in CSF and Serum From Patients With Primary Progressive Multiple Sclerosis: Potential of Serum GFAP as Disease Severity Marker?
In: Frontiers in Neurology, Bd. 10, 280: S. 1-9
[PDF, 1MB]
Abraham, G.; Malik, Rainer; Yonova-Doing, E.; Salim, Agus; Wang, T.; Danesh, John; Butterworth, Adam S.; Howson, Joanna M. M.; Inouye, M. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(20. Dezember 2019):
Genomic risk score offers predictive performance comparable to clinical risk factors for ischaemic stroke.
In: Nature Communications, 5819
[PDF, 1MB]
Aftabizadeh, Maryam; Tatarek-Nossol, Marianna; Andreetto, Erika; El Bounkari, Omar; Kipp, Markus; Beyer, Cordian; Latz, Eicke; Bernhagen, Jürgen und Kapurniotu, Aphrodite
(2019):
Blocking Inflammasome Activation Caused by beta-Amyloid Peptide (A beta) and Islet Amyloid Polypeptide (IAPP) through an IAPP Mimic.
In: ACS Chemical Neuroscience, Bd. 10, Nr. 8: S. 3703-3717
[PDF, 2MB]
Alexopoulos, Panagiotis; Thierjung, Nathalie; Economou, Polychronis; Werle, Lukas; Buhl, Felix; Kagerbauer, Simone; Papanastasiou, Anastasios D.; Grimmer, Timo; Gourzis, Philippos; Berthele, Achim; Hemmer, Bernhard; Kuebler, Hubert; Martin, Jan; Politis, Antonios und Perneczky, Robert
(2019):
Plasma Levels of Soluble A beta PP beta as a Biomarker for Alzheimer's Disease with Dementia.
In: Journal of Alzheimers Disease, Bd. 69, Nr. 1: S. 83-90
Andreas, Nico; Potthast, Maria; Geiselhoeringer, Anna-Lena; Garg, Garima; de Jong, Renske; Riewaldt, Julia; Russkamp, Dennis; Riemann, Marc; Girard, Jean-Philippe; Blank, Simon; Kretschmer, Karsten; Schmidt-Weber, Carsten; Korn, Thomas; Weih, Falk und Ohnmacht, Caspar
(2019):
RelB Deficiency in Dendritic Cells Protects from Autoimmune Inflammation Due to Spontaneous Accumulation of Tissue T Regulatory Cells.
In: Journal of Immunology, Bd. 203, Nr. 10: S. 2602-2613
[PDF, 1MB]
Baker, Emily; Sims, Rebecca; Leonenko, Ganna; Frizzati, Aura; Harwood, Janet C.; Grozeva, Detelina; Morgan, Kevin; Passmore, Peter; Holmes, Clive; Powell, John; Brayne, Carol; Gill, Michael; Mead, Simon; Bossu, Paola; Spalletta, Gianfranco; Cruchaga, Carlos; Maier, Wolfgang; Heun, Reinhard; Jessen, Frank; Peters, Oliver; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Frölich, Lutz; Ramirez, Alfredo; Jones, Lesley; Hardy, John; Ivanov, Dobril; Hill, Matthew; Holmans, Peter; Allen, Nicholas D.; Morgan, B. Paul; Seshadri, Sudha; Schellenberg, Gerard D.; Amouyel, Philippe; Williams, Julie und Escott-Price, Valentina
(2019):
Gene-based analysis in HRC imputed genome wide association data identifies three novel genes for Alzheimer's disease.
In: PLOS One
14(7), e0218111
[PDF, 905kB]
Balk, Lisanne J.; Coric, Danko; Knier, Benjamin; Zimmermann, Hanna G.; Behbehani, Raed; Alroughani, Raed; Martinez-Lapiscina, Elena H.; Brandt, Alexander U.; Sanchez-Dalmau, Bernardo; Vidal-Jordana, Angela; Albrecht, Philipp; Koska, Valeria; Havla, Joachim; Pisa, Marco; Nolan, Rachel C.; Leocani, Letizia; Paul, Friedemann; Aktas, Orhan; Montalban, Xavier; Balcer, Laura J.; Villoslada, Pablo; Outteryck, Olivier; Korn, Thomas und Petzold, Axel
(2019):
Retinal inner nuclear layer volume reflects inflammatory disease activity in multiple sclerosis;a longitudinal OCT study.
In: Multiple Sclerosis Journal-Experimental Translational and Clinical, Bd. 5, Nr. 3
[PDF, 1MB]
Bartels, Martin; Weckbecker, Daniel; Kuhn, Peer-Hendrik; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Lichtenthaler, Stefan F.; Boetzel, Kai und Giese, Armin
(2019):
Iron-mediated aggregation and toxicity in a novel neuronal cell culture model with inducible alpha-synuclein expression.
In: Scientific Reports, Bd. 9, 9100
[PDF, 7MB]
Baumann, Peter; Schriever, Sonja C.; Kullmann, Stephanie; Zimprich, Annemarie; Feuchtinger, Annette; Amarie, Oana; Peter, Andreas; Walch, Axel; Gailus-Durner, Valerie; Fuchs, Helmut; de Angelis, Martin Hrabe; Wurst, Wolfgang; Tschoep, Matthias H.; Heni, Martin; Hoelter, Sabine M. und Pfluger, Paul T.
(2019):
Dusp8 affects hippocampal size and behavior in mice and humans.
In: Scientific Reports, Bd. 9, 19483
[PDF, 1MB]
Bax, Bridget E.; Levene, Michelle; Bain, Murray D.; Fairbanks, Lynette D.; Filosto, Massimiliano; Ucar, Sema Kalkan; Klopstock, Thomas ORCID: https://orcid.org/0000-0003-2805-4652; Kornblum, Cornelia; Mandel, Hanna; Rahman, Shamima; Roubertie, Agathe; Scarpelli, Mauro; Sedgwick, Philip M.; Baru, Moshe; Sellos-Moura, Marcia; Price, Jeanie; Horn, Patrick und Nirmalananthan, Niranjanan
(2019):
Erythrocyte Encapsulated Thymidine Phosphorylase for the Treatment of Patients with Mitochondrial Neurogastrointestinal Encephalomyopathy: Study Protocol for a Multi-Centre, Multiple Dose, Open Label Trial.
In: Journal of Clinical Medicine, Bd. 8, Nr. 8, 1096
[PDF, 1MB]
Beltran, Eduardo; Gerdes, Lisa Ann; Hansen, Julia; Flierl-Hecht, Andrea; Krebs, Stefan; Blum, Helmut; Ertl-Wagner, Birgit; Barkhof, Frederik; Kuempfel, Tania; Hohlfeld, Reinhard und Dornmair, Klaus
(2019):
Early adaptive immune activation detected in monozygotic twins with prodromal multiple sclerosis.
In: Journal of Clinical Investigation, Bd. 129, Nr. 11: S. 4758-4768
[PDF, 5MB]
Beyer, Leonie; Schnabel, Jonas; Kazmierczak, Philipp; Ewers, Michael; Schönecker, Sonja; Prix, Catharina; Meyer-Wilmes, Johanna; Unterrainer, Marcus; Catak, Cihan; Pogarell, Oliver; Perneczky, Robert; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Bartenstein, Peter; Danek, Adrian; Buerger, Katharina; Levin, Johannes; Rominger, Axel und Brendel, Matthias
(2019):
Neuronal injury biomarkers for assessment of the individual cognitive reserve in clinically suspected Alzheimer's disease.
In: Neuroimage-Clinical, Bd. 24, 101949
[PDF, 3MB]
Bittner, Stefan; Engel, Sinah; Lange, Christoph; Weber, Martin S.; Haghikia, Aiden; Luessi, Felix; Korn, Thomas; Klotz, Luisa; Bayas, Antonios; Paul, Friedemann; Heesen, Christoph; Stangel, Martin; Wildemann, Brigitte; Bergh, Florian Then; Tackenberg, Björn; Trebst, Corinna; Warnke, Clemens; Linker, Ralf; Kerschensteiner, Martin; Zettl, Uwe; Tumani, Hayrettin; Brueck, Wolfgang; Meuth, Sven G.; Kuempfel, Tanja; Hemmer, Bernhard; Wiendl, Heinz; Gold, Ralf und Zipp, Frauke
(2019):
Diagnostik und Therapie von Tuberkulose unter Immuntherapien für Multiple Sklerose. Aktueller Stand und Empfehlungen in Deutschland.
In: Nervenarzt, Bd. 90, Nr. 12: S. 1245-1253
Blumenstock, Sonja; Angelo, Maria Florencia; Peters, Finn; Dorostkar, Mario M.; Ruf, Viktoria C.; Luckner, Manja; Crux, Sophie; Slapakova, Lenka; Arzberger, Thomas; Claverol, Stephane; Herzog, Etienne und Herms, Jochen
(2019):
Early defects in translation elongation factor 1 alpha levels at excitatory synapses in alpha-synucleinopathy.
In: Acta Neuropathologica, Bd. 138, Nr. 6: S. 971-986
[PDF, 8MB]
Brendel, Matthias; Deussing, Maximilian; Blume, Tanja; Kaiser, Lena; Probst, Federico; Overhoff, Felix; Peters, Finn; Ungern-Sternberg, Barbara von; Ryazanov, Sergey; Leonov, Andrei; Griesinger, Christian; Zwergal, Andreas; Levin, Johannes; Bartenstein, Peter; Yakushev, Igor; Cumming, Paul; Boening, Guido; Ziegler, Sibylle; Herms, Jochen; Giese, Armin und Rominger, Axel
(2019):
Late-stage Anle138b treatment ameliorates tau pathology and metabolic decline in a mouse model of human Alzheimer's disease tau.
In: Alzheimer's Research & Therapy, Bd. 11, 67
[PDF, 7MB]
Brenner, David; Rosenbohm, Angela; Yilmaz, Ruestem; Mueller, Kathrin; Grehl, Torsten; Petri, Susanne; Meyer, Thomas; Grosskreutz, Julian; Weydt, Patrick; Ruf, Wolfgang; Neuwirth, Christoph; Weber, Markus; Pinto, Susana; Claeys, Kristl G.; Schrank, Berthold; Jordan, Berit; Knehr, Antje; Guenther, Kornelia; Huebers, Annemarie; Zeller, Daniel; Kubisch, Christian; Jablonka, Sibylle; Sendtner, Michael; Klopstock, Thomas; de Carvalho, Mamede; Sperfeld, Anne; Borck, Guntram; Volk, Alexander E.; Dorst, Johannes; Weis, Joachim; Otto, Markus; Schuster, Joachim; Del Tredici, Kelly; Braak, Heiko; Danzer, Karin M.; Freischmidt, Axel; Meitinger, Thomas; Ludolph, Albert C.; Andersen, Peter M.; Weishaupt, Jochen H.; Weyen, Ute; Hermann, Andreas; Winkler, Juergen; Hagenacker, Tim; Koch, Jan Christoph; Lingor, Paul; Goericke, Bettina; Zierz, Stephan; Baum, Petra; Wolf, Joachim; Winkler, Andrea; Young, Peter; Bogdahn, Ulrich; Prudlo, Johannes und Kassubek, Jan
(2019):
Reply: Adult-onset distal spinal muscular atrophy: a new phenotype associated with KIF5A mutations.
In: Brain, Bd. 142, e67
[PDF, 190kB]
Brummer, Tobias; Müller, Stephan A.; Pan-Montojo, Francisco; Yoshida, Fumiaki; Fellgiebel, Andreas; Tomita, Taisuke; Endres, Kristina und Lichtenthaler, Stefan F.
(2019):
NrCAM is a marker for substrate-selective activation of ADAM10 in Alzheimer's disease.
In: EMBO Molecular Medicine, Bd. 11, Nr. 4, e9695
[PDF, 3MB]
Burgold, Johanna; Schulz-Trieglaff, Elena Katharina; Voelkl, Kerstin; Gutierrez-Angel, Sara; Bader, Jakob Maximilian; Hosp, Fabian; Mann, Matthias; Arzberger, Thomas; Klein, Rüdiger; Liebscher, Sabine und Dudanova, Irina
(2019):
Cortical circuit alterations precede motor impairments in Huntington's disease mice.
In: Scientific Reports, Bd. 9, 6634
[PDF, 4MB]
Centonze, Federica G.; Reiterer, Veronika; Nalbach, Karsten; Saito, Kota; Pawlowski, Krzysztof; Behrends, Christian und Farhan, Hesso
(2019):
LTK is an ER-resident receptor tyrosine kinase that regulates secretion.
In: Journal of Cell Biology, Bd. 218, Nr. 8: S. 2470-2480
[PDF, 2MB]
Chung, Jaeyoon; Marini, Sandro; Pera, Joanna; Norrving, Bo; Jimenez-Conde, Jordi; Roquer, Jaume; Fernandez-Cadenas, Israel; Tirschwell, David L.; Selim, Magdy; Brown, Devin L.; Silliman, Scott L.; Worrall, Bradford B.; Meschia, James F.; Demel, Stacie; Greenberg, Steven M.; Slowik, Agnieszka; Lindgren, Arne; Schmidt, Reinhold; Traylor, Matthew; Sargurupremraj, Muralidharan; Tiedt, Steffen; Malik, Rainer; Debette, Stephanie; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Langefeld, Carl D.; Woo, Daniel; Rosand, Jonathan und Anderson, Christopher D.
(2019):
Genome-wide association study of cerebral small vessel disease reveals established and novel loci.
In: Brain, Bd. 142: S. 3176-3189
[PDF, 922kB]
Coarelli, Giulia; Schule, Rebecca; van de Warrenburg, Bart P. C.; De Jonghe, Peter; Ewenczyk, Claire; Martinuzzi, Andrea; Synofzik, Matthis; Hamer, Elisa G.; Baets, Jonathan; Anheim, Mathieu; Schoels, Ludger; Deconinck, Tine; Masrori, Pegah; Fontaine, Bertrand; Klockgether, Thomas; D'Angelo, Maria Grazia; Monin, Marie-Lorraine; De Bleecker, Jan; Migeotte, Isabelle; Charles, Perrine; Bassi, Maria Teresa; Klopstock, Thomas; Mochel, Fanny; Ollagnon-Roman, Elisabeth; D'Hooghe, Marc; Kamm, Christoph; Kurzwelly, Delia; Papin, Melanie; Davoine, Claire-Sophie; Banneau, Guillaume; du Montcel, Sophie Tezenas; Seilhean, Danielle; Brice, Alexis; Duyckaerts, Charles; Stevanin, Giovanni und Durr, Alexandra
(2019):
Loss of paraplegin drives spasticity rather than ataxia in a cohort of 241 patients with SPG7.
In: Neurology, Bd. 92, Nr. 23, E2679-E2690
Costa Jordao, Marta Joana; Sankowski, Roman; Brendecke, Stefanie M.; Locatelli, Giuseppe; Tai, Yi-Heng; Tay, Tuan Leng; Schramm, Eva; Armbruster, Stephan; Hagemeyer, Nora; Gross, Olaf; Mai, Dominic; Cicek, Ozgun; Falk, Thorsten; Kerschensteiner, Martin; Grun, Dominic und Prinz, Marco
(2019):
Single-cell profiling identifies myeloid cell subsets with distinct fates during neuroinflammation.
In: Science, Bd. 363, Nr. 6425, eaat7554
Czamara, Darina; Eraslan, Goekcen; Page, Christian M.; Lahti, Jari; Lahti-Pulkkinen, Marius; Hamalainen, Esa; Kajantie, Eero; Laivuori, Hannele; Villa, Pia M.; Reynolds, Rebecca M.; Nystad, Wenche; Haberg, Siri E.; London, Stephanie J.; O'Donnell, Kieran J.; Garg, Elika; Meaney, Michael J.; Entringer, Sonja; Wadhwa, Pathik D.; Buss, Claudia; Jones, Meaghan J.; Lin, David T. S.; MacIsaac, Julie L.; Kobor, Michael S.; Koen, Nastassja; Zar, Heather J.; Koenen, Karestan C.; Dalvie, Shareefa; Stein, Dan J.; Kondofersky, Ivan; Müller, Nikola S.; Theis, Fabian J.; Raikkonen, Katri; Binder, Elisabeth B.; Wray, Naomi R.; Ripke, Stephan; Mattheisen, Manuel; Trzaskowski, Maciej; Byrne, Enda M.; Abdellaoui, Abdel; Adams, Mark J.; Agerbo, Esben; Air, Tracy M.; Andlauer, Till F. M.; Bacanu, Silviu-Alin; Baekvad-Hansen, Marie; Beekman, Aartjan T. F.; Bigdeli, Tim B.; Blackwood, Douglas H. R.; Bryois, Julien; Buttenschon, Henriette N.; Bybjerg-Grauholm, Jonas; Cai, Na; Castelao, Enrique; Christensen, Jane Hvarregaard; Clarke, Toni-Kim; Coleman, Jonathan R.; Colodro-Conde, Lucia; Couvy-Duchesne, Baptiste; Craddock, Nick; Crawford, Gregory E.; Davies, Gail; Deary, Ian J.; Degenhardt, Franziska; Derks, Eske M.; Direk, Nese; Dolan, Conor; Dunn, Erin C.; Eley, Thalia C.; Escott-Price, Valentina; Kiadeh, Farnush Farhadi Hassan; Finucane, Hilary K.; Forstner, Andreas J.; Frank, Josef; Gaspar, Helena A.; Gill, Michael; Goes, Fernando S.; Gordon, Scott D.; Grove, Jakob; Hall, Lynsey S.; Hansen, Christine Soholm; Hansen, Thomas F.; Herms, Stefan; Hickie, Ian B.; Hoffmann, Per; Homuth, Georg; Horn, Carsten; Hottenga, Jouke-Jan; Hougaard, David M.; Ising, Marcus; Jansen, Rick; Jörgenson, Eric; Knowles, James A.; Kohane, Isaac S.; Kraft, Julia; Kretzschmar, Warren W.; Krogh, Jesper; Kutalik, Zoltan; Li, Yihan; Lind, Penelope A.; MacIntyre, Donald J.; MacKinnon, Dean F.; Maier, Robert M.; Maier, Wolfgang; Marchini, Jonathan; Mbarek, Hamdi; McGrath, Patrick; McGuffin, Peter; Medland, Sarah E.; Mehta, Divya; Middeldorp, Christel M.; Mihailov, Evelin; Milaneschi, Yuri; Milani, Lili; Mondimore, Francis M.; Montgomery, Grant W.; Mostafavi, Sara; Mullins, Niamh; Nauck, Matthias; Ng, Bernard; Nivard, Michel G.; Nyholt, Dale R.; O'Reilly, Paul F.; Oskarsson, Hogni; Owen, Michael J.; Painter, Jodie N.; Pedersen, Carsten Bocker; Pedersen, Marianne Girtz; Peterson, Roseann E.; Pettersson, Erik; Peyrot, Wouter J.; Pistis, Giorgio; Posthuma, Danielle; Quiroz, Jörge A.; Qvist, Per; Rice, John P.; Riley, Brien P.; Rivera, Margarita; Mirza, Saira Saeed; Schoevers, Robert; Schulte, Eva C.; Shen, Ling; Shi, Jianxin; Shyn, Stanley; Sigurdsson, Engilbert; Sinnamon, Grant C. B.; Smit, Johannes H.; Smith, Daniel J.; Stefansson, Hreinn; Steinberg, Stacy; Streit, Fabian; Strohmaier, Jana; Tansey, Katherine E.; Teismann, Henning; Teumer, Alexander; Thompson, Wesley; Thomson, Pippa A.; Thorgeirsson, Thorgeir E.; Traylor, Matthew; Treutlein, Jens; Trubetskoy, Vassily; Uitterlinden, Andre G.; Umbricht, Daniel; Van der Auwera, Sandra; van Hemert, Albert M.; Viktorin, Alexander; Visscher, Peter M.; Wang, Yunpeng; Webb, Bradley T.; Weinsheimer, Shantel Marie; Wellmann, Jürgen; Willemsen, Gonneke; Witt, Stephanie H.; Wu, Yang; Xi, Hualin S.; Yang, Jian; Zhang, Futao; Arolt, Volker; Baune, Bernhard T.; Berger, Klaus; Boomsma, Dorret; Cichon, Sven; Dannlowski, Udo; de Geus, E. J. C.; DePaulo, J. Raymond; Domenici, Enrico; Domschke, Katharina; Esko, Tonu; Grabe, Hans J.; Hamilton, Steven P.; Hayward, Caroline; Heath, Andrew C.; Kendler, Kenneth S.; Kloiber, Stefan; Lewis, Glyn; Li, Qingqin S.; Lucae, Susanne; Madden, Pamela A. F.; Magnusson, Patrik K.; Martin, Nicholas G.; McIntosh, Andrew M.; Metspalu, Andres; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Nordentoft, Merete; Noethen, Markus M.; O'Donovan, Michael C.; Paciga, Sara A.; Pedersen, Nancy L.; Penninx, Brenda W. J. H.; Perlis, Roy H.; Porteous, David J.; Potash, James B.; Preisig, Martin; Rietschel, Marcella; Schäfer, Catherine; Schulze, Thomas G.; Smoller, Jordan W.; Stefansson, Kari; Tiemeier, Henning; Uher, Rudolf; Voelzke, Henry; Weissman, Myrna M.; Werge, Thomas; Lewis, Cathryn M.; Levinson, Douglas F.; Breen, Gerome; Borglum, Anders D. und Sullivan, Patrick F.
(2019):
Integrated analysis of environmental and genetic influences on cord blood DNA methylation in new-borns.
In: Nature Communications, Bd. 10, 2548
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Dana, Hod; Sun, Yi; Mohar, Boaz; Hulse, Brad K.; Kerlin, Aaron M.; Hasseman, Jeremy P.; Tsegaye, Getahun; Tsang, Arthur; Wong, Allan; Patel, Ronak; Macklin, John J.; Chen, Yang; Konnerth, Arthur; Jayaraman, Vivek; Looger, Loren L.; Schreiter, Eric R.; Svoboda, Karel und Kim, Douglas S.
(2019):
High-performance calcium sensors for imaging activity in neuronal populations and microcompartments.
In: Nature Methods, Bd. 16, Nr. 7:
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Dannheisig, David P.; Beck, Eileen; Calzia, Enrico; Walther, Paul; Behrends, Christian und Pfister, Astrid S.
(2019):
Loss of Peter Pan (PPAN) Affects Mitochondrial Homeostasis and Autophagic Flux.
In: Cells, Bd. 8, Nr. 8, 894
[PDF, 11MB]
De Guio, Francois; Duering, Marco; Fazekas, Franz; De Leeuw, Frank-Erik; Greenberg, Steven M.; Pantoni, Leonardo; Aghetti, Agnes; Smith, Eric E.; Wardlaw, Joanna und Jouvent, Eric
(2019):
Brain atrophy in cerebral small vessel diseases: Extent, consequences, technical limitations and perspectives: The HARNESS initiative.
In: Journal of Cerebral Blood Flow and Metabolism, Bd. 40, Nr. 2: S. 231-245
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Deming, Yuetiva; Filipello, Fabia; Cignarella, Francesca; Cantoni, Claudia; Hsu, Simon; Mikesell, Robert; Li, Zeran; Del-Aguila, Jörge L.; Dube, Umber; Farias, Fabiana Geraldo; Bradley, Joseph; Budde, John; Ibanez, Laura; Fernandez, Maria Victoria; Blennow, Kaj; Zetterberg, Henrik; Heslegrave, Amanda; Johansson, Per M.; Svensson, Johan; Nellgard, Bengt; Lleo, Alberto; Alcolea, Daniel; Clarimon, Jordi; Rami, Lorena; Molinuevo, Jose Luis; Suarez-Calvet, Marc; Morenas-Rodriguez, Estrella; Kleinberger, Gernot; Ewers, Michael; Harari, Oscar; Haass, Christian; Brett, Thomas J.; Benitez, Bruno A.; Karch, Celeste M.; Piccio, Laura und Cruchaga, Carlos
(2019):
The MS4A gene cluster is a key modulator of soluble TREM2 and Alzheimer's disease risk.
In: Science Translational Medicine, Bd. 11, Nr. 505, eaau2291
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Deretic, Vojo; Prossnitz, Eric; Burge, Mark; Campen, Matthew J.; Cannon, Judy; Liu, Ke Jian; Liu, Meilian; Hall, Pamela; Sklar, Larry A.; Allers, Lee; Mariscal, Luisa; Garcia, Sally Ann; Weaver, John; Baehrecke, Eric H.; Behrends, Christian; Cecconi, Francesco; Codogno, Patrice; Chen, Guang-Chao; Elazar, Zvulun; Eskelinen, Eeva-Liisa; Fourie, Bernard; Gozuacik, Devrim; Hong, Wanjin; Jo, Eun-Kyeong; Johansen, Terje; Juhasz, Gabor; Kimch, Adi; Ktistakis, Nicholas; Kroemer, Guido; Mizushima, Noboru; Muenz, Christian; Reggiori, Fulvio; Rubinsztein, David; Ryan, Kevin; Schroder, Kate; Shen, Han-Min; Simonsen, Anne; Tooze, Sharon A.; Vaccaro, Maria; Yoshimori, Tamotsu; Yu, Li; Zhang, Hong und Klionsky, Daniel J.
(2019):
Autophagy, Inflammation, and Metabolism (AIM) Center in its second year.
In: Autophagy, Bd. 15, Nr. 10: S. 1829-1833
Dias, Mariana Castro; Coisne, Caroline; Baden, Pascale; Enzmann, Gaby; Garrett, Lillian; Becker, Lore; Hoelter, Sabine M.; de Angelis, Martin Hrabe; Deutsch, Urban; Engelhardt, Britta; Aguilar-Pimentel, Antonio; Adler, Thure; Busch, Dirk H.; Spielmann, Nadine; Moreth, Kristin; Hans, Wolfgang; Amarie, Oana; Graw, Jochen; Rozman, Jan; Radc, Ildiko; Neff, Frauke; Calzada-Wack, Julia; Rathkolb, Birgit; Wolf, Eckhard; Klopstock, Thomas; Wurst, Wolfgang; Beckers, Johannes; Oestereicher, Manuela; Miller, Gregor; Maier, Holger; Stoeger, Claudia; Leuchtenberger, Stefanie; Gailus-Durner, Valerie und Fuchs, Helmut
(2019):
Claudin-12 is not required for blood-brain barrier tight junction function.
In: Fluids and Barriers of the Cns, Bd. 16, Nr. 1, 30
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Diehl-Schmid, Janine; Licata, Abigail; Goldhardt, Oliver; Foerstl, Hans; Yakushew, Igor; Otto, Markus; Anderl-Straub, Sarah; Beer, Ambros; Ludolph, Albert Christian; Landwehrmeyer, Georg Bernhard; Levin, Johannes; Danek, Adrian; Fliessbach, Klaus; Spottke, Annika; Fassbender, Klaus; Lyros, Epameinondas; Prudlo, Johannes; Krause, Bernd Joachim; Volk, Alexander; Edbauer, Dieter; Schroeter, Matthias Leopold; Drzezga, Alexander; Kornhuber, Johannes; Lauer, Martin; Ackl, Nibal; Arnim, Christine V.; Brumberg, Joachim; Gaertner, Florian; Jahn, Holger; Kasper, Elisabeth; Kassubek, Jan; Prix, Catharina; Riedl, Lina; Rossmeier, Carola; Schönecker, Sonja; Semler, Elisa; Teipel, Stefan; Westerteicher, Christine; Wlasich, Elisabeth und Grimmer, Timo
(2019):
FDG-PET underscores the key role of the thalamus in frontotemporal lobar degeneration caused by C9ORF72 mutations.
In: Translational Psychiatry, Bd. 9, 54
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Djannatian, Minou; Timmler, Sebastian; Arends, Martina; Luckner, Manja; Weil, Marie-Theres; Alexopoulos, Ioannis; Snaidero, Nicolas; Schmid, Bettina; Misgeld, Thomas; Moebius, Wiebke; Schifferer, Martina; Peles, Elior und Simons, Mikael
(2019):
Two adhesive systems cooperatively regulate axon ensheathment and myelin growth in the CNS.
In: Nature Communications, Bd. 10, 4794
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Dorst, Johannes; Chen, Lu; Rosenbohm, Angela; Dreyhaupt, Jens; Huebers, Annemarie; Schuster, Joachim; Weishaupt, Jochen H.; Kassubek, Jan; Gess, Burkhard; Meyer, Thomas; Weyen, Ute; Hermann, Andreas; Winkler, Jürgen; Grehl, Torsten; Hagenacker, Tim; Lingor, Paul; Koch, Jan C.; Sperfeld, Anne; Petri, Susanne; Grosskreutz, Julian; Metelmann, Moritz; Wolf, Joachim; Winkler, Andrea S.; Klopstock, Thomas; Boentert, Matthias; Johannesen, Siw; Storch, Alexander; Schrank, Bertold; Zeller, Daniel; Liu, Xiao-lu; Tang, Lu; Fan, Dong-Sheng und Ludolph, Albert C.
(2019):
Prognostic factors in ALS: a comparison between Germany and China.
In: Journal of Neurology, Bd. 266, Nr. 6: S. 1516-1525
Duering, Marco; Adam, Ruth; Wollenweber, Frank A.; Bayer-Karpinska, Anna; Baykara, Ebru; Cubillos-Pinilla, Leidy Y.; Gesierich, Benno; Caballero, Miguel A. Araque; Stöcklein, Sophia; Ewers, Michael; Pasternak, Ofer und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2019):
Within-lesion heterogeneity of subcortical DWI lesion evolution, and stroke outcome: A voxel-based analysis.
In: Journal of Cerebral Blood Flow and Metabolism, Bd. 40, Nr. 7: S. 1482-1491
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Eichinger, Paul; Schoen, Simon; Pongratz, Viola; Wiestler, Hanni; Zhang, Haike; Bussas, Matthias; Hoshi, Muna-Miriam; Kirschke, Jan; Berthele, Achim; Zimmer, Claus; Hemmer, Bernhard; Muehlau, Mark und Wiestler, Benedikt
(2019):
Accuracy of Unenhanced MRI in the Detection of New Brain Lesions in Multiple Sclerosis.
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Addressing a real‐life problem: treatment with intravenous thrombolysis and mechanical thrombectomy in acute stroke patients with an extended time window beyond 4.5 h based on computed tomography perfusion imaging.
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The nucleolus functions as a phase-separated protein quality control compartment.
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Association of Intrathecal Immunoglobulin G Synthesis With Disability Worsening in Multiple Sclerosis.
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Use of Genetic Variants Related to Antihypertensive Drugs to Inform on Efficacy and Side Effects.
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Vascular contributions to cognitive impairment and dementia: Research consortia that focus on etiology and treatable targets to lessen the burden of dementia worldwide.
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A beta-induced acceleration of Alzheimer-related tau-pathology spreading and its association with prion protein.
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Evidence for a white matter lesion size threshold to support the diagnosis of relapsing remitting multiple sclerosis.
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Plasminogen activator inhibitor-1 augments damage by impairing fibrinolysis after traumatic brain injury.
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Cardiovascular Risk and Atherosclerosis Progression in Hypertensive Persons Treated to Blood Pressure Targets.
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CD8(+) T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome.
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Translational research on reserve against neurodegenerative disease: consensus report of the International Conference on Cognitive Reserve in the Dementias and the Alzheimer's Association Reserve, Resilience and Protective Factors Professional Interest Area working groups.
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Automated segmentation of changes in FLAIR-hyperintense white matter lesions in multiple sclerosis on serial magnetic resonance imaging.
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PET Imaging of Astrogliosis and Tau Facilitates Diagnosis of Parkinsonian Syndromes.
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Hepatic Rab24 controls blood glucose homeostasis via improving mitochondrial plasticity.
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Dendritic Cell Accumulation in the Gut and Central Nervous System Is Differentially Dependent on alpha 4 Integrins.
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Iron-Sequestering Nanocompartments as Multiplexed Electron Microscopy Gene Reporters.
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Genome-wide association study identifies 30 loci associated with bipolar disorder.
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Brain-resident memory T cells generated early in life predispose to autoimmune disease in mice.
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Iron Metabolism, Hepcidin, and Mortality (the Ludwigshafen Risk and Cardiovascular Health Study).
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A prospective study of serum metabolites and risk of ischemic stroke.
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Clinical, pathophysiological and genetic features of motor symptoms in autosomal dominant Alzheimer's disease.
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Genetic Variants in the Promoter Region of the Macrophage Migration Inhibitory Factor are Associated with the Severity of Hepatitis C Virus-Induced Liver Fibrosis.
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QUINT: Workflow for Quantification and Spatial Analysis of Features in Histological Images From Rodent Brain.
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ApoE attenuates unresolvable inflammation by complex formation with activated C1q.
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Epigenetic upregulation of FKBP5 by aging and stress contributes to NF-κB-driven inflammation and cardiovascular risk.
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Active poly-GA vaccination prevents microglia activation and motor deficits in a C9orf72 mouse model.
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A vicious cycle of β amyloid-dependent neuronal hyperactivation.
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Serum neurofilament light chain in genetic frontotemporal dementia: a longitudinal, multicentre cohort study.
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A nonsynonymous mutation in PLCG2 reduces the risk of Alzheimer's disease, dementia with Lewy bodies and frontotemporal dementia, and increases the likelihood of longevity.
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A Novel Chimeric Oncolytic Virus Vector for Improved Safety and Efficacy as a Platform for the Treatment of Hepatocellular Carcinoma.
In: Journal of Virology, Bd. 92, Nr. 23, e01386-18
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The USP8 mutational status may predict long‐term remission in patients with Cushing's disease.
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Laboratory mouse housing conditions can be improved using common environmental enrichment without compromising data.
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Early uneven ear input induces long-lasting differences in left-right motor function.
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Progressive multifocal leukoencephalopathy after fingolimod treatment.
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Clinical Routine FDG-PET Imaging of Suspected Progressive Supranuclear Palsy and Corticobasal Degeneration: A Gatekeeper for Subsequent TauPET Imaging?
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Treatment choices and neuropsychological symptoms of a large cohort of early MS.
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The wide genetic landscape of clinical frontotemporal dementia: systematic combined sequencing of 121 consecutive subjects.
In: Genetics in Medicine, Bd. 20, Nr. 2: S. 240-249
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BACE1 Inhibitor MK-8931 Alters Formation but Not Stability of Dendritic Spines.
In: Frontiers in Aging Neuroscience, Bd. 10, 229
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Microglial response to increasing amyloid load saturates with aging: a longitudinal dual tracer in vivo PET-study.
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CXCR4 involvement in neurodegenerative diseases.
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Efficacy of chronic BACE1 inhibition in PS2APP mice depends on the regional A beta deposition rate and plaque burden at treatment initiation.
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Comparison of F-18-T807 and F-18-THK5117 PET in a Mouse Mode of Tau Pathology.
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Blockade of MCAM/CD146 impedes CNS infiltration of T cells over the choroid plexus.
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Immune-related genetic enrichment in frontotemporal dementia: An analysis of genome-wide association studies.
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Understanding the role of the perivascular space in cerebral small vessel disease.
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White matter diffusion alterations precede symptom onset in autosomal dominant Alzheimer’s disease.
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Defective cholesterol clearance limits remyelination in the aged central nervous system.
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(2018):
Brain diffusion tensor imaging changes in cerebrotendinous xanthomatosis reversed with treatment.
In: Journal of Neurology, Bd. 265, Nr. 2: S. 388-393
Causevic, Mirsada; Dominko, Kristina; Malnar, Martina; Vidatic, Lea; Cermak, Stjepko; Pigoni, Martina; Kuhn, Peer-Hendrik; Colombo, Alessio; Havas, Daniel; Flunkert, Stefanie; McDonald, Jessica; Gunnersen, Jenny M.; Hutter-Paier, Birgit; Tahirovic, Sabina; Windisch, Manfred; Krainc, Dimitri; Lichtenthaler, Stefan F. und Hecimovic, Silva
(2018):
BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains.
In: PLOS One
13(7), e0200344
[PDF, 74MB]
Chang, H.; Hoshina, N.; Zhang, C.; Ma, Y.; Cao, H.; Wang, Y.; Wu, D-d; Bergen, S. E.; Landen, M.; Hultman, C. M.; Preisig, M.; Kutalik, Z.; Castelao, E.; Grigoroiu-Serbanescu, M.; Forstner, A. J.; Strohmaier, J.; Hecker, J.; Schulze, T. G.; Müller-Myhsok, B.; Reif, A.; Mitchell, P. B.; Martin, N. G.; Schofield, P. R.; Cichon, S.; Nöthen, M. M.; Walter, H.; Erk, S.; Heinz, A.; Amin, N.; Duijn, C. M. van; Meyer-Lindenberg, A.; Tost, H.; Xiao, X.; Yamamoto, T.; Rietschel, M. und Li, M.
(2018):
The protocadherin 17 gene affects cognition, personality, amygdala structure and function, synapse development and risk of major mood disorders.
In: Molecular Psychiatry, Bd. 23, Nr. 2: S. 400-412
Danhauser, Katharina; Alhaddad, Bader; Makowski, Christine; Piekutowska-Abramczuk, Dorota; Syrbe, Steffen; Gomez-Ospina, Natalia; Manning, Melanie A.; Kostera-Pruszczyk, Anna; Krahn-Peper, Claudia; Berutti, Riccardo; Kovacs-Nagy, Reka; Gusic, Mirjana; Graf, Elisabeth; Laugwitz, Lucia; Roeblitz, Michaela; Wroblewski, Andreas; Hartmann, Hans; Das, Anibh M.; Bueltmann, Eva; Fang, Fang; Xu, Manting; Schatz, Ulrich A.; Karall, Daniela; Zellner, Herta; Haberlandt, Edda; Feichtinger, Rene G.; Mayr, Johannes A.; Meitinger, Thomas; Prokisch, Holger; Strom, Tim M.; Ploski, Rafal; Hoffmann, Georg F.; Pronicki, Maciej; Bonnen, Penelope E.; Morlot, Susanne und Haack, Tobias B.
(2018):
Bi-allelic ADPRHL2 Mutations Cause Neurodegeneration with Developmental Delay, Ataxia, and Axonal Neuropathy.
In: American Journal of Human Genetics, Bd. 103, Nr. 5: S. 817-825
Debette, S.; Strbian, D.; Wardlaw, J. M.; Worp, H. B. van der; Rinkel, G. J. E.; Caso, V. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2018):
Fourth European stroke science workshop.
In: European Stroke Journal, Bd. 3, Nr. 3: S. 206-219
[PDF, 183kB]
Deussing, Maximilian; Blume, Tanja; Vomacka, Lena; Mahler, Christoph; Focke, Carola; Todica, Andrei; Unterrainer, Marcus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2018):
Coupling between physiological TSPO expression in brain and myocardium allows stabilization of late-phase cerebral [F-18]GE180 PET quantification.
In: Neuroimage, Bd. 165: S. 83-91
Deussing, Maximilian; Blume, Tanja; Vomacka, Lena; Mahler, Christoph; Focke, Carola; Todica, Andrei; Unterrainer, Marcus; Albert, Nathalie L. ORCID: https://orcid.org/0000-0003-0953-7624; Lindner, Simon; Ungern-Sternberg, Barbara von; Baumann, Karlheinz; Zwergal, Andreas; Bartenstein, Peter; Herms, Jochen; Rominger, Axel und Brendel, Matthias
(2018):
Data on specificity of [F-18]GE180 uptake for TSPO expression in rodent brain and myocardium.
In: Data in Brief, Bd. 19: S. 331-336
[PDF, 1MB]
Di Giaimo, Rossella; Durovic, Tamara; Barquin, Pablo; Kociaj, Anita; Lepko, Tjasa; Aschenbroich, Sven; Breunig, Christopher T.; Irmler, Martin; Cernilogar, Filippo M.; Schotta, Gunnar; Barbosa, Joana S.; Trümbach, Dietrich; Baumgart, Emily Violette; Neuner, Andrea M.; Beckers, Johannes; Wurst, Wolfgang; Stricker, Stefan H. und Ninkovic, Jovica
(2018):
The Aryl Hydrocarbon Receptor Pathway Defines the Time Frame for Restorative Neurogenesis.
In: Cell Reports, Bd. 25, Nr. 12: S. 3241-3251
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Duering, Marco; Finsterwalder, Sofia; Baykara, Ebru; Tuladhar, Anil Man; Gesierich, Benno; Konieczny, Marek J.; Malik, Rainer; Franzmeier, Nicolai; Ewers, Michael; Jouvent, Eric; Biessels, Geert Jan; Schmidt, Reinhold; Leeuw, Frank-Erik de; Pasternak, Ofer und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2018):
Free water determines diffusion alterations and clinical status in cerebral small vessel disease.
In: Alzheimers & Dementia, Bd. 14, Nr. 6: S. 764-774
Duering, Marco; Konieczny, Marek J.; Tiedt, Steffen; Baykara, Ebru; Tuladhar, Anil Man; Leijsen, Esther van; Lyrer, Philippe; Engelter, Stefan T.; Gesierich, Benno; Achmüller, Melanie; Barro, Christian; Adam, Ruth; Ewers, Michael; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Kuhle, Jens; Leeuw, Frank-Erik de und Peters, Nils
(2018):
Serum Neurofilament Light Chain Levels Are Related to Small Vessel Disease Burden.
In: Journal of Stroke, Bd. 20, Nr. 2: S. 228-238
Duernberger, Yvonne; Liu, Shu; Riemschoss, Katrin; Paulsen, Lydia; Bester, Romina; Kuhn, Peer-Hendrik; Schölling, Manuel; Lichtenthaler, Stefan F. und Vorberg, Ina
(2018):
Prion Replication in the Mammalian Cytosol: Functional Regions within a Prion Domain Driving Induction, Propagation, and Inheritance.
In: Molecular and Cellular Biology, Bd. 38, Nr. 15
[PDF, 8MB]
Dörr, Jan; Wernecke, Klaus-Dieter; Wuerfel, Jens; Bellmann-Strobl, Judith; Siffrin, Volker; Saettler, Muriel B.; Simons, Mikael; Linsa, Andreas; Tumani, Hayrettin und Paul, Friedemann
(2018):
Disease Modification in Multiple Sclerosis by Flupirtine-Results of a Randomized Placebo Controlled Phase II Trial.
In: Frontiers in Neurology, Bd. 9, 842
[PDF, 543kB]
Ederle, Helena; Funk, Christina; Abou-Ajram, Claudia; Hutten, Saskia; Funk, Eva B. E.; Kehlenbach, Ralph H.; Bailer, Susanne M. und Dormann, Dorothee
(2018):
Nuclear egress of TDP-43 and FUS occurs independently of Exportin-1/CRM1.
In: Scientific Reports, Bd. 8, 7084
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Erhart, Gertraud; Lamina, Claudia; Lehtimaki, Terho; Marques-Vidal, Pedro; Kahonen, Mika; Vollenweider, Peter; Raitakari, Olli T.; Waeber, Gerard; Thorand, Barbara; Strauch, Konstantin; Gieger, Christian; Meitinger, Thomas; Peters, Annette; Kronenberg, Florian und Coassin, Stefan
(2018):
Genetic Factors Explain a Major Fraction of the 50% Lower Lipoprotein(a) Concentrations in Finns.
In: Arteriosclerosis Thrombosis and Vascular Biology, Bd. 38, Nr. 5: S. 1230-1241
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Fornasiero, Eugenio F.; Mandad, Sunit; Wildhagen, Hanna; Alevra, Mihai; Rammner, Burkhard; Keihani, Sarva; Opazo, Felipe; Urban, Inga; Ischebeck, Till; Sakib, M. Sadman; Fard, Maryam K.; Kirli, Koray; Centeno, Tonatiuh Pena; Vidal, Ramon O.; Rahman, Raza-Ur; Benito, Eva; Fischer, Andre; Dennerlein, Sven; Rehling, Peter; Feussner, Ivo; Bonn, Stefan; Simons, Mikael; Urlaub, Henning und Rizzoli, Silvio O.
(2018):
Precisely measured protein lifetimes in the mouse brain reveal differences across tissues and subcellular fractions.
In: Nature Communications, Bd. 9, 4230
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Franceschini, Nora; Giambartolomei, Claudia; Vries, Paul S. de; Finan, Chris; Bis, Joshua C.; Huntley, Rachael P.; Lovering, Ruth C.; Tajuddin, Salman M.; Winkler, Thomas W.; Graff, Misa; Kavousi, Maryam; Dale, Caroline; Smith, Albert V.; Hofer, Edith; Leeuwen, Elisabeth M. van; Nolte, Ilja M.; Lu, Lingyi; Scholz, Markus; Sargurupremraj, Muralidharan; Pitkanen, Niina; Franzen, Oscar; Joshi, Peter K.; Noordam, Raymond; Marioni, Riccardo E.; Hwang, Shih-Jen; Musani, Solomon K.; Schminke, Ulf; Palmas, Walter; Isaacs, Aaron; Correa, Adolfo; Zonderman, Alan B.; Hofman, Albert; Teumer, Alexander; Cox, Amanda J.; Uitterlinden, Andre G.; Wong, Andrew; Smit, Andries J.; Newman, Anne B.; Britton, Annie; Ruusalepp, Arno; Sennblad, Bengt; Hedblad, Bo; Pasaniuc, Bogdan; Penninx, Brenda W.; Langefeld, Carl D.; Wassel, Christina L.; Tzourio, Christophe; Fava, Cristiano; Baldassarre, Damiano; O'Leary, Daniel H.; Teupser, Daniel; Kuh, Diana; Tremoli, Elena; Mannarino, Elmo; Grossi, Enzo; Börwinkle, Eric; Schadt, Eric E.; Ingelsson, Erik; Veglia, Fabrizio; Rivadeneira, Fernando; Beutner, Frank; Chauhan, Ganesh; Heiss, Gerardo; Snieder, Harold; Campbell, Harry; Völzke, Henry; Markus, Hugh S.; Deary, Ian J.; Jukema, J. Wouter; Graaf, Jacqueline de; Price, Jacqueline; Pott, Janne; Hopewell, Jemma C.; Liang, Jingjing; Thiery, Joachim; Engmann, Jorgen; Gertow, Karl; Rice, Kenneth; Taylor, Kent D.; Dhana, Klodian; Kiemeney, Lambertus A. L. M.; Lind, Lars; Raffield, Laura M.; Launer, Lenore J. und Holdt, Lesca M.
(2018):
GWAS and colocalization analyses implicate carotid intima-media thickness and carotid plaque loci in cardiovascular outcomes.
In: Nature Communications, Bd. 9, 5141
[PDF, 1MB]
Franzmeier, Nicolai; Düzel, Emrah; Jessen, Frank; Bürger, Katharina; Levin, Johannes; Duering, Marco; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Suarez-Calvet, Marc; Fagan, Anne M.; Paumier, Katrina; Benzinger, Tammie; Masters, Colin L.; Morris, John C.; Perneczky, Robert; Janowitz, Daniel; Catak, Cihan; Wolfsgruber, Steffen; Wagner, Michael; Teipel, Stefan; Kilimann, Ingo; Ramirez, Alfredo; Rossor, Martin; Jucker, Mathias; Chhatwal, Jasmeer; Spottke, Annika; Böcker, Henning; Brosseron, Frederic; Falkai, Peter ORCID: https://orcid.org/0000-0003-2873-8667; Fliessbach, Klaus; Heneka, Michael T.; Laske, Christoph; Nestor, Peter; Peters, Oliver; Fuentes, Manuel; Menne, Felix; Priller, Josef; Spruth, Eike J.; Franke, Christiana; Schneider, Anja; Kofler, Barbara; Westerteicher, Christine; Speck, Oliver; Wiltfang, Jens; Bartels, Claudia; Caballero, Miguel Angel Araque; Metzger, Coraline; Bittner, Daniel; Weiner, Michael; Lee, Jae-Hong; Salloway, Stephen; Danek, Adrian; Goate, Alison; Schofield, Peter R.; Bateman, Randall J. und Ewers, Michael
(2018):
Left frontal hub connectivity delays cognitive impairment in autosomal-dominant and sporadic Alzheimer’s disease.
In: Brain, Bd. 141: S. 1186-1200
Franzmeier, Nicolai; Hartmann, Julia; Taylor, Alexander N. W.; Araque-Caballero, Miguel A.; Simon-Vermot, Lee; Kambeitz-Ilankovic, Lana; Bürger, Katharina; Catak, Cihan; Janowitz, Daniel; Müller, Claudia; Ertl-Wagner, Birgit; Stahl, Robert; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X; Duering, Marco und Ewers, Michael
(2018):
The left frontal cortex supports reserve in aging by enhancing functional network efficiency.
In: Alzheimers Research & Therapy
10:28
[PDF, 3MB]
Fussi, Natascha; Höllerhage, Matthias; Chakroun, Tasnim; Nykänen, Niko-Petteri; Roesler, Thomas W.; Köglsperger, Thomas; Wurst, Wolfgang; Behrends, Christian und Höglinger, Guenter U.
(2018):
Exosomal secretion of alpha-synuclein as protective mechanism after upstream blockage of macroautophagy.
In: Cell Death & Disease, Bd. 9, 757
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Garrett, Lillian; Becker, Lore; Rozman, Jan; Puk, Oliver; Stoeger, Tobias; Yildirim, Ali Onder; Bohla, Alexander; Eickelberg, Oliver; Hans, Wolfgang; Prehn, Cornelia; Adamski, Jerzy; Klopstock, Thomas; Racz, Ildiko; Zimmer, Andreas; Klingenspor, Martin; Fuchs, Helmut; Gailus-Durner, Valerie; Wurst, Wolfgang; Hrabe de Angelis, Martin; Graw, Jochen und Hölter, Sabine M.
(2018):
Fgf9(Y162C) Mutation Alters Information Processing and Social Memory in Mice.
In: Molecular Neurobiology, Bd. 55, Nr. 6: S. 4580-4595
Gelderblom, Mathias; Gallizioli, Mattia; Ludewig, Peter; Thom, Vivien; Arunachalam, Priyadharshini; Rissiek, Björn; Bernreuther, Christian; Glatzel, Markus; Korn, Thomas; Arumugam, Thiruma Valavan; Sedlacik, Jan; Gerloff, Christian; Tolosa, Eva; Planas, Anna M. und Magnus, Tim
(2018):
IL-23 (Interleukin-23)-Producing Conventional Dendritic Cells Control the Detrimental IL-17 (Interleukin-17) Response in Stroke.
In: Stroke, Bd. 49, Nr. 1: S. 155-164
Gruber, Anselm; Hornburg, Daniel; Antonin, Matthias; Krahmer, Natalie; Collado, Javier; Schaffer, Miroslava; Zubaite, Greta; Luechtenborg, Christian; Sachsenheimer, Timo; Bruegger, Britta; Mann, Matthias; Baumeister, Wolfgang; Hartl, F. Ulrich; Hipp, Mark S. und Fernandez-Busnadiego, Ruben
(2018):
Molecular and structural architecture of polyQ aggregates in yeast.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 115, Nr. 15, E3446-E3453
Guo, Qiang; Lehmer, Carina; Martinez-Sanchez, Antonio; Rudack, Till; Beck, Florian; Hartmann, Hannelore; Perez-Berlanga, Manuela; Frottin, Frederic; Hipp, Mark S.; Hartl, F. Ulrich; Edbauer, Dieter; Baumeister, Wolfgang und Fernandez-Busnadiego, Ruben
(2018):
In Situ Structure of Neuronal C9orf72 Poly-GA Aggregates Reveals Proteasome Recruitment.
In: Cell, Bd. 172, Nr. 4: S. 696-705
Haeusler, Darius; Haeusser-Kinzel, Silke; Feldmann, Linda; Torke, Sebastian; Lepennetier, Gildas; Bernard, Claude C. A.; Zamvil, Scott S.; Brueck, Wolfgang; Lehmann-Horn, Klaus und Weber, Martin S.
(2018):
Functional characterization of reappearing B cells after anti-CD20 treatment of CNS autoimmune disease.
In: Proceedings of the National Academy of Sciences of the United States of America, Bd. 115, Nr. 39: S. 9773-9778
Hartlage-Ruebsamen, Maike; Bluhm, Alexandra; Piechotta, Anke; Linnert, Miriam; Rahfeld, Jens-Ulrich; Demuth, Hans-Ulrich; Lues, Inge; Kuhn, Peer-Hendrik; Lichtenthaler, Stefan F.; Rossner, Steffen und Hoefling, Corinna
(2018):
Immunohistochemical Evidence from APP-Transgenic Mice for Glutaminyl Cyclase as Drug Target to Diminish pE-Abeta Formation.
In: Molecules, Bd. 23, Nr. 4, 924
[PDF, 48MB]
Hartmann, Hannelore; Hornburg, Daniel; Czuppa, Mareike; Bader, Jakob; Michaelsen, Meike; Farny, Daniel; Arzberger, Thomas; Mann, Matthias; Meissner, Felix und Edbauer, Dieter
(2018):
Proteomics and C9orf72 neuropathology identify ribosomes as poly-GR/PR interactors driving toxicity.
In: Life Science Alliance, Bd. 1, Nr. 2, e201800070
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Herber, Julia; Njavro, Jasenka; Feederle, Regina; Schepers, Ute; Müller, Ulrike C.; Braese, Stefan; Müller, Stephan A. und Lichtenthaler, Stefan F.
(2018):
Click Chemistry-mediated Biotinylation Reveals a Function for the Protease BACE1 in Modulating the Neuronal Surface Glycoproteome.
In: Molecular & Cellular Proteomics, Bd. 17, Nr. 8: S. 1487-1501
Hertelendy, Johannes; Reumuth, Georg; Simons, David; Stoppe, Christian; Kim, Bong-Sung; Stromps, Jan-Philipp; Fuchs, Paul C.; Bernhagen, Jürgen; Pallua, Norbert und Grieb, Gerrit
(2018):
Macrophage Migration Inhibitory Factor - A Favorable Marker in Inflammatory Diseases?
In: Current Medicinal Chemistry, Bd. 25, Nr. 5: S. 601-605
Hock, Eva-Maria; Maniecka, Zuzanna; Hruska-Plochan, Marian; Reber, Stefan; Laferriere, Florent; Sahadevan, Sonu M. K.; Ederle, Helena; Gittings, Lauren; Pelkmans, Lucas; Dupuis, Luc; Lashley, Tammaryn; Ruepp, Marc-David; Dormann, Dorothee und Polymenidou, Magdalini
(2018):
Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function.
In: Cell Reports, Bd. 24, Nr. 4: S. 987-1000
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Hong, Wei; Wang, Zemin; Liu, Wen; O'Malley, Tiernan T.; Jin, Ming; Willem, Michael; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Frosch, Matthew P. und Walsh, Dominic M.
(2018):
Diffusible, highly bioactive oligomers represent a critical minority of soluble A beta in Alzheimer's disease brain.
In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 19-40
Irving, Stephanie; Schöberl, Florian; Pradhan, Cauchy; Brendel, Matthias; Bartenstein, Peter; Dieterich, Marianne; Brandt, Thomas und Zwergal, Andreas
(2018):
A novel real-space navigation paradigm reveals age- and gender-dependent changes of navigational strategies and hippocampal activation.
In: Journal of Neurology, Bd. 265, Nr. Suppl. 1: S. 113-126
Jabbari, Edwin; Woodside, John; Tan, Manuela M. X.; Shoai, Maryam; Pittman, Alan; Ferrari, Raffaele; Mok, Kin Y.; Zhang, David; Reynolds, Regina H.; Silva, Rohan de; Grimm, Max-Joseph; Respondek, Gesine; Müller, Ulrich; Al-Sarraj, Safa; Gentleman, Stephen M.; Lees, Andrew J.; Warner, Thomas T.; Hardy, John; Revesz, Tamas; Höglinger, Guenter U.; Holton, Janice L.; Ryten, Mina und Morris, Huw R.
(2018):
Variation at the TRIM11 locus modifies progressive supranuclear palsy phenotype.
In: Annals of Neurology, Bd. 84, Nr. 4: S. 485-496
Jong, Simone de; Abdalla Diniz, Mateus Jose; Saloma, Andiara; Gadelha, Ary; Santoro, Marcos L.; Ota, Vanessa K.; Noto, Cristiano; Curtis, Charlesg; Newhouse, Stephen J.; Patel, Hamel; Hall, Lynsey S.; O'Reilly, Paul F.; Belangero, Sintia I.; Bressan, Rodrigo A.; Breen, Gerome; Wray, Naomi R.; Ripke, Stephan; Mattheisen, Manuel; Trzaskowski, Maciej; Byrne, Enda M.; Abdellaoui, Abdel; Adams, Mark J.; Agerbo, Esben; Air, Tracy M.; Andlauer, Till F. M.; Bacanu, Silviu-Alin; Baekvad-Hansen, Marie; Beekman, Aartjan T. F.; Bigdeli, Tim B.; Binder, Elisabeth B.; Blackwood, Douglas H. R.; Bryois, Julien; Buttenschon, Henriette N.; Bybjerg-Grauholm, Jonas; Cai, Na; Castelao, Enrique; Christensen, Jane Hvarregaard; Clarke, Toni-Kim; Coleman, Jonathan R. 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Applying polygenic risk scoring for psychiatric disorders to a large family with bipolar disorder and major depressive disorder.
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Selective Genetic Overlap Between Amyotrophic Lateral Sclerosis and Diseases of the Frontotemporal Dementia Spectrum.
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Apheresis therapies for NMOSD attacks A retrospective study of 207 therapeutic interventions.
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Myeloid-derived suppressor cells control B cell accumulation in the central nervous system during autoimmunity.
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Arginine Methylation Regulates MEIS2 Nuclear Localization to Promote Neuronal Differentiation of Adult SVZ Progenitors.
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MacroH2A histone variants limit chromatin plasticity through two distinct mechanisms.
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DNA methylation as a mediator of HLA-DRB1(star)15:01 and a protective variant in multiple sclerosis.
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Genetic Susceptibility Loci for Cardiovascular Disease and Their Impact on Atherosclerotic Plaques.
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A novel CHCHD10 mutation implicates a Mia40-dependent mitochondrial import deficit in ALS.
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Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders.
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Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model.
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Label-free 3D-CLEM Using Endogenous Tissue Landmarks.
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Genome-wide meta-analysis identifies 3 novel loci associated with stroke.
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Whole-Brain Analysis of Cells and Circuits by Tissue Clearing and Light-Sheet Microscopy.
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Friedreich and dominant ataxias: quantitative differences in cerebellar dysfunction measurements.
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[PDF, 363kB]
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ECTRIMS/EAN guideline on the pharmacological treatment of people with multiple sclerosis.
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ECTRIMS/EAN Guideline on the pharmacological treatment of people with multiple sclerosis.
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Gene set enrichment analysis and expression pattern exploration implicate an involvement of neurodevelopmental processes in bipolar disorder.
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Comprehensive analysis of the mutation spectrum in 301 German ALS families.
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Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation.
In: Nature Communications, Bd. 9, 335
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Cellular Mechanisms Controlling Surfacing of AICL Glycoproteins, Cognate Ligands of the Activating NK Receptor NKp80.
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Action Plan for Stroke in Europe 2018-2030.
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Simultaneous recording of cervical and ocular vestibular-evoked myogenic potentials.
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BACE1 inhibition more effectively suppresses initiation than progression of beta-amyloid pathology.
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Potential genetic modifiers of disease risk and age at onset in patients with frontotemporal lobar degeneration and GRN mutations: a genome-wide association study.
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From Epigenetic Associations to Biological and Psychosocial Explanations in Mental Health.
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Multi-ethnic genome-wide association study for atrial fibrillation.
In: Nature Genetics, Bd. 50, Nr. 9: S. 1225-1233
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Brain-released alarmins and stress response synergize in accelerating atherosclerosis progression after stroke.
In: Science Translational Medicine, Bd. 10, Nr. 432, eaao1313
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Genetic risk, incident stroke, and the benefits of adhering to a healthy lifestyle: cohort study of 306 473 UK Biobank participants.
In: BMJ-British Medical Journal, Bd. 363, k4168
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K-variant BCHE and pesticide exposure: Gene-environment interactions in a case-control study of Parkinson's disease in Egypt.
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FoxO Function Is Essential for Maintenance of Autophagic Flux and Neuronal Morphogenesis in Adult Neurogenesis.
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Neuron-specific inactivation of Wt1 alters locomotion in mice and changes interneuron composition in the spinal cord.
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Diagnostic exome sequencing in early-onset Parkinson's disease confirms VPS13C as a rare cause of autosomal-recessive Parkinson's disease.
In: Clinical Genetics, Bd. 93, Nr. 3: S. 603-612
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Atrophy in the Thalamus But Not Cerebellum Is Specific for C9orf72 FTD and ALS Patients - An Atlas-Based Volumetric MRI Study.
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Antibiotics protect against EAE by increasing regulatory and anti-inflammatory cells.
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Gait analysis in PSP and NPH Dual-task conditions make the difference.
In: Neurology, Bd. 90, Nr. 12, E1021-E1028
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Arginine Methyltransferase PRMT8 Provides Cellular Stress Tolerance in Aging Motoneurons.
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CCPG1 Is a Non-canonical Autophagy Cargo Receptor Essential for ER-Phagy and Pancreatic ER Proteostasis.
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Soluble CD74 Reroutes MIF/CXCR4/AKT-Mediated Survival of Cardiac Myofibroblasts to Necroptosis.
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The protective role of macrophage migration inhibitory factor in acute kidney injury after cardiac surgery.
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CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline.
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TSPO PET with [F-18]GE-180 sensitively detects focal neuroinflammation in patients with relapsing-remitting multiple sclerosis.
In: European Journal of Nuclear Medicine and Molecular Imaging, Bd. 45, Nr. 8: S. 1423-1431
Vincenz-Donnelly, Lisa; Holthusen, Hauke; Koerner, Roman; Hansen, Erik C.; Presto, Jenny; Johansson, Jan; Sawarkar, Ritwick; Hartl, F. Ulrich und Hipp, Mark S.
(2018):
High capacity of the endoplasmic reticulum to prevent secretion and aggregation of amyloidogenic proteins.
In: EMBO Journal, Bd. 37, Nr. 3: S. 337-350
Weber, Axel; Schwarz, Sigrid C.; Tost, Jörg; Truembach, Dietrich; Winter, Pia; Busato, Florence; Tacik, Pawel; Windhorst, Anita C.; Fagny, Maud; Arzberger, Thomas; McLean, Catriona; Swieten, John C. van; Schwarz, Johannes; Weisenhorn, Daniela Vogt; Wurst, Wolfgang; Adhikary, Till; Dickson, Dennis W.; Höglinger, Günter U. und Müller, Ulrich
(2018):
Epigenome-wide DNA methylation profiling in Progressive Supranuclear Palsy reveals major changes at DLX1.
In: Nature Communications, Bd. 9, 2929
[PDF, 1MB]
Wettmarshausen, Jennifer; Goh, Valerie; Huang, Kai-Ting; Arduino, Daniela M.; Tripathi, Utkarsh; Leimpek, Anja; Cheng, Yiming; Pittis, Alexandros A.; Gabaldon, Toni; Mokranjac, Dejana; Hajnoczky, Gyorgy und Perocchi, Fabiana
(2018):
MICU1 Confers Protection from MCU-Dependent Manganese Toxicity.
In: Cell Reports, Bd. 25, Nr. 6: S. 1425-1435
[PDF, 3MB]
Winkelmann, Juliane; Allen, Richard P.; Högl, Birgit; Inoue, Yuichi; Oertel, Wolfgang; Salminen, Aaro V.; Winkelman, John W.; Trenkwalder, Claudia und Sampaio, Cristina
(2018):
Treatment of Restless Legs Syndrome: Evidence-Based Review and Implications for Clinical Practice (Revised 2017).
In: Movement Disorders, Bd. 33, Nr. 7: S. 1077-1091
Woodsmith, Jonathan; Casado-Medrano, Victoria; Benlasfer, Nouhad; Eccles, Rebecca L.; Hutten, Saskia; Heine, Christian L.; Thormann, Verena; Abou-Ajram, Claudia; Rocks, Oliver; Dormann, Dorothee und Stelzl, Ulrich
(2018):
Interaction modulation through arrays of clustered methyl-arginine protein modifications.
In: Life Science Alliance, Bd. 1, Nr. 5, e201800178
[PDF, 2MB]
Wray, Naomi R.; Ripke, Stephan; Mattheisen, Manuel; Trzaskowski, Maciej; Byrne, Enda M.; Abdellaoui, Abdel; Adams, Mark J.; Agerbo, Esben; Air, Tracy M.; Andlauer, Till M. F.; Bacanu, Silviu-Alin; Baekvad-Hansen, Marie; Beekman, Aartjan F. T.; Bigdeli, Tim B.; Binder, Elisabeth B.; Blackwood, Douglas R. H.; Bryois, Julien; Buttenschon, Henriette N.; Bybjerg-Grauholm, Jonas; Cai, Na; Castelao, Enrique; Christensen, Jane Hvarregaard; Clarke, Toni-Kim; Coleman, Jonathan I. R.; Colodro-Conde, Lucia; Couvy-Duchesne, Baptiste; Craddock, Nick; Crawford, Gregory E.; Crowley, Cheynna A.; Dashti, Hassan S.; Davies, Gail; Deary, Ian J.; Degenhardt, Franziska; Derks, Eske M.; Direk, Nese; Dolan, Conor V.; Dunn, Erin C.; Eley, Thalia C.; Eriksson, Nicholas; Escott-Price, Valentina; Kiadeh, Farnush Hassan Farhadi; Finucane, Hilary K.; Forstner, Andreas J.; Frank, Josef; Gaspar, Helena A.; Gill, Michael; Giusti-Rodriguez, Paola; Goes, Fernando S.; Gordon, Scott D.; Grove, Jakob; Hall, Lynsey S.; Hannon, Eilis; Hansen, Christine Soholm; Hansen, Thomas F.; Herms, Stefan; Hickie, Ian B.; Hoffmann, Per; Homuth, Georg; Horn, Carsten; Hottenga, Jouke-Jan; Hougaard, David M.; Hu, Ming; Hyde, Craig L.; Ising, Marcus; Jansen, Rick; Jin, Fulai; Jorgenson, Eric; Knowles, James A.; Kohane, Isaac S.; Kraft, Julia; Kretzschmar, Warren W.; Krogh, Jesper; Kutalik, Zoltan; Lane, Jacqueline M.; Li, Yihan; Li, Yun; Lind, Penelope A.; Liu, Xiaoxiao; Lu, Leina; MacIntyre, Donald J.; MacKinnon, Dean F.; Maier, Robert M.; Maier, Wolfgang; Marchini, Jonathan; Mbarek, Hamdi; McGrath, Patrick; McGuffin, Peter; Medland, Sarah E.; Mehta, Divya; Middeldorp, Christel M.; Mihailov, Evelin; Milaneschi, Yuri; Milani, Lili; Mill, Jonathan; Mondimore, Francis M.; Montgomery, Grant W.; Mostafavi, Sara; Mullins, Niamh; Nauck, Matthias; Ng, Bernard; Nivard, Michel G.; Nyholt, Dale R.; O'Reilly, Paul F.; Oskarsson, Hogni; Owen, Michael J.; Painter, Jodie N.; Pedersen, Carsten Bocker; Pedersen, Marianne Giortz; Peterson, Roseann E.; Pettersson, Erik; Peyrot, Wouter J.; Pistis, Giorgio; Posthuma, Danielle; Purcell, Shaun M.; Quiroz, Jorge A.; Qvist, Per; Rice, John P.; Riley, Brien P.; Rivera, Margarita; Mirza, Saira Saeed; Saxena, Richa; Schövers, Robert; Schulte, Eva C.; Shen, Ling; Shi, Jianxin; Shyn, Stanley I.; Sigurdsson, Engilbert; Sinnamon, Grant B. C.; Smit, Johannes H.; Smith, Daniel J.; Stefansson, Hreinn; Steinberg, Stacy; Stockmeier, Craig A.; Streit, Fabian; Strohmaier, Jana; Tansey, Katherine E.; Teismann, Henning; Teumer, Alexander; Thompson, Wesley; Thomson, Pippa A.; Thorgeirsson, Thorgeir E.; Tian, Chao; Traylor, Matthew; Treutlein, Jens; Trubetskoy, Vassily; Uitterlinden, Andre G.; Umbricht, Daniel; Auwera, Sandra van der; Hemert, Albert M. van; Viktorin, Alexander; Visscher, Peter M.; Wang, Yunpeng; Webb, Bradley T.; Weinsheimer, Shantel Marie; Wellmann, Juegen; Willemsen, Gonneke; Witt, Stephanie H.; Wu, Yang; Xi, Hualin S.; Yang, Jian; Zhang, Futao; Arolt, Volker; Baune, Bernhard T.; Berger, Klaus; Boomsma, Dorret I.; Cichon, Sven; Dannlowski, Udo; Geus, E. C. J. de; DePaulo, J. Raymond; Domenici, Enrico; Domschke, Katharina; Esko, Tonu; Grabe, Hans J.; Hamilton, Steven P.; Hayward, Caroline; Heath, Andrew C.; Hinds, David A.; Kendler, Kenneth S.; Kloiber, Stefan; Lewis, Glyn; Li, Qingqin S.; Lucae, Susanne; Madden, Pamela F. A.; Magnusson, Patrik K.; Martin, Nicholas G.; McIntosh, Andrew M.; Metspalu, Andres; Mors, Ole; Mortensen, Preben Bo; Müller-Myhsok, Bertram; Nordentoft, Merete; Nöthen, Markus M.; O'Donovan, Michael C.; Paciga, Sara A.; Pedersen, Nancy L.; Penninx, Brenda W. J. H.; Perlis, Roy H.; Porteous, David J.; Potash, James B.; Preisig, Martin; Rietschel, Marcella; Schaefer, Catherine; Schulze, Thomas G.; Smoller, Jordan W.; Stefansson, Kari; Tiemeier, Henning; Uher, Rudolf; Völzke, Henry; Weissman, Myrna M.; Werge, Thomas; Winslow, Ashley R.; Lewis, Cathryn M.; Levinson, Douglas F.; Breen, Gerome; Borglum, Anders D. und Sullivan, Patrick F.
(2018):
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
In: Nature Genetics, Bd. 50, Nr. 5: S. 668-681
Xiang, Xianyuan; Piers, Thomas M.; Wefers, Benedikt; Zhu, Kaichuan; Mallach, Anna; Brunner, Bettina; Kleinberger, Gernot; Song, Wilbur; Colonna, Marco; Herms, Jochen; Wurst, Wolfgang; Pocock, Jennifer M. und Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627
(2018):
The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans.
In: Molecular Neurodegeneration
13:49
[PDF, 2MB]
Zellner, Andreas; Scharrer, Eva; Arzberger, Thomas; Oka, Chio; Domenga-Denier, Valerie; Joutel, Anne; Lichtenthaler, Stefan F.; Müller, Stephan A.; Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X und Haffner, Christof
(2018):
CADASIL brain vessels show a HTRA1 loss-of-function profile.
In: Acta Neuropathologica, Bd. 136, Nr. 1: S. 111-125
Zhu, Kaichuan; Xiang, Xianyuan; Filser, Severin; Marinkovic, Petar; Dorostkar, Mario M.; Crux, Sophie; Neumann, Ulf; Shimshek, Derya R.; Rammes, Gerhard; Haass, Christian ORCID: https://orcid.org/0000-0002-4869-1627; Lichtenthaler, Stefan F.; Gunnersen, Jenny M. und Herms, Jochen
(2018):
Beta-Site Amyloid Precursor Protein Cleaving Enzyme 1 Inhibition Impairs Synaptic Plasticity via Seizure Protein 6.
In: Biological Psychiatry, Bd. 83, Nr. 5: S. 428-437
Zietemann, Vera; Georgakis, Marios K.; Dondaine, Thibaut; Müller, Claudia; Mendyk, Anne-Marie; Kopczak, Anna; Henon, Hilde; Bombois, Stephanie; Wollenweber, Frank Arne; Bordet, Regis und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2018):
Early MoCA predicts long-term cognitive and functional outcome and mortality after stroke.
In: Neurology, Bd. 91, Nr. 20, E1838-E1850
[PDF, 738kB]
Zimmermann, Hanna G.; Knier, Benjamin; Oberwahrenbrock, Timm; Behrens, Janina; Pfuhl, Catherina; Aly, Lilian; Kaminski, Miriam; Hoshi, Muna-Miriam; Specovius, Svenja; Giess, Rene M.; Scheel, Michael; Mühlau, Mark; Bellmann-Strobl, Judith; Ruprecht, Klemens; Hemmer, Bernhard; Korn, Thomas; Paul, Friedemann und Brandt, Alexander U.
(2018):
Association of Retinal Ganglion Cell Layer Thickness With Future Disease Activity in Patients With Clinically Isolated Syndrome.
In: Jama Neurology, Bd. 75, Nr. 9: S. 1071-1079
Zimprich, Annemarie; Ostereicher, Manuela A.; Becker, Lore; Dirscherl, Petra; Ernst, Luise; Fuchs, Helmut; Gailus-Durner, Valerie; Garrett, Lillian; Giesert, Florian; Glasl, Lisa; Hummel, Angelika; Rozman, Jan; Hrabe de Angelis, Martin; Vogt-Weisenhorn, Daniela; Wurst, Wolfgang und Hölter, Sabine M.
(2018):
Analysis of locomotor behavior in the German Mouse Clinic.
In: Journal of Neuroscience Methods, Bd. 300: S. 77-91
2016
Beaufort, N.; Scharrer, E.; Kremmer, E.; Lux, V.; Ehrmann, M.; Huber, R.; Houlden, H.; Werring, D.; Haffner, C. und Dichgans, Martin ORCID: https://orcid.org/0000-0002-0654-387X
(2016):
Cerebral small vessel disease-related protease HtrA1 processes latent TGF-beta binding protein 1 and facilitates TGF-beta signalling.
In: Journal of Cerebral Blood Flow and Metabolism, Bd. 36: S. 746
Jiang, Jie; Zhu, Qiang; Gendron, Tania F.; Saberi, Shahram; McAlonis-Downes, Melissa; Seelman, Amanda; Stauffer, Jennifer E.; Jafar-nejad, Paymaan; Drenner, Kevin; Schulte, Derek; Chun, Seung; Sun, Shuying; Ling, Shuo-Chien; Myers, Brian; Engelhardt, Jeffery; Katz, Melanie; Baughn, Michael; Platoshyn, Oleksandr; Marsala, Martin; Watt, Andy; Heyser, Charles J.; Ard, M. Colin; Muynck, Louis de; Daughrity, Lillian M.; Swing, Deborah A.; Tessarollo, Lino; Jung, Chris J.; Delpoux, Arnaud; Utzschneider, Daniel T.; Hedrick, Stephen M.; Jong, Pieter J. de; Edbauer, Dieter; Damme, Philip van; Petrucelli, Leonard; Shaw, Christopher E.; Bennett, C. Frank; Da Cruz, Sandrine; Ravits, John; Rigo, Frank; Cleveland, Don W. und Lagier-Tourenne, Clotilde
(2016):
Gain of Toxicity from ALS/FTD-Linked Repeat Expansions in C9ORF72 Is Alleviated by Antisense Oligonucleotides Targeting GGGGCC-Containing RNAs.
In: Neuron, Bd. 90, Nr. 3: S. 535-550
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