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Gruber, Tim und Garcia-Caceres, Cristina (2022): Astroglial clean-up of satiety synapses. In: Nature Metabolism, Bd. 4, Nr. 5: S. 505-506

Volltext auf 'Open Access LMU' nicht verfügbar.

Abstract

Until now, the BDNF-TrkB signalling pathway was thought to be exclusively regulated by neurons. Ameroso et al. show that astrocytic TrkB.T1 is a critical substrate of BDNF in the regulation of energy balance and that its defective signalling in hypothalamic circuits leads to obesity.

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